Regulation of small GTPases by GEFs, GAPs, and GDIs von Cherfils, Jacqueline, Zeghouf, Mahel

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Ras superfamily GEFs and GAPs: validated and tractable targets for cancer therapy? von Vigil, Dominico, Cherfils, Jacqueline, Rossman, Kent L., Der, Channing J.

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Multiple interactions between an Arf/GEF complex and charged lipids determine activation kinetics on the membrane von Karandur, Deepti, Nawrotek, Agata, Kuriyan, John, Cherfils, Jacqueline

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A Ca2+-regulated deAMPylation switch in human and bacterial FIC proteins von Veyron, Simon, Oliva, Giulia, Rolando, Monica, Buchrieser, Carmen, Peyroche, Gérald, Cherfils, Jacqueline

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Small GTPase signaling hubs at the surface of cellular membranes in physiology and disease von Cherfils, Jacqueline

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Membranes prime the RapGEF EPAC1 to transduce cAMP signaling von Sartre, Candice, Peurois, François, Ley, Marie, Kryszke, Marie-Hélène, Zhang, Wenhua, Courilleau, Delphine, Fischmeister, Rodolphe, Ambroise, Yves, Zeghouf, Mahel, Cianferani, Sarah, Ferrandez, Yann, Cherfils, Jacqueline

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Arf GTPases and their effectors: assembling multivalent membrane-binding platforms von Cherfils, Jacqueline

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Structural snapshots of the mechanism and inhibition of a guanine nucleotide exchange factor von Renault, Louis, Guibert, Bernard, Cherfils, Jacqueline

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Interfacial inhibition of macromolecular interactions: nature's paradigm for drug discovery von Pommier, Yves, Cherfils, Jacqueline

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Mapping the Cellular Response to Small Molecules Using Chemogenomic Fitness Signatures von Lee, Anna Y., St.Onge, Robert P., Proctor, Michael J., Wallace, Iain M., Nile, Aaron H., Spagnuolo, Paul A., Jitkova, Yulia, Gronda, Marcela, Wu, Yan, Kim, Moshe K., Cheung-Ong, Kahlin, Torres, Nikko P., Spear, Eric D., Han, Mitchell K. L., Schlecht, Ulrich, Suresh, Sundari, Duby, Geoffrey, Heisler, Lawrence E., Surendra, Anuradha, Fung, Eula, Urbanus, Malene L., Gebbia, Marinella, Lissina, Elena, Miranda, Molly, Chiang, Jennifer H., Aparicio, Ana Maria, Zeghouf, Mahel, Davis, Ronald W., Cherfils, Jacqueline, Boutry, Marc, Kaiser, Chris A., Cummins, Carolyn L., Trimble, William S., Brown, Grant W., Schimmer, Aaron D., Bankaitis, Vytas A., Nislow, Corey, Bader, Gary D., Giaever, Guri

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MglA functions as a three-state GTPase to control movement reversals of Myxococcus xanthus von Galicia, Christian, Lhospice, Sébastien, Varela, Paloma Fernández, Trapani, Stefano, Zhang, Wenhua, Navaza, Jorge, Herrou, Julien, Mignot, Tâm, Cherfils, Jacqueline

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On the explicit use of experimental images in high resolution cryo-EM refinement [version 1; peer review: 2 approved] von Cherfils, Jacqueline, Navaza, Jorge

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Encoding Allostery in mTOR Signaling: The Structure of the Rag GTPase/Ragulator Complex von Cherfils, Jacqueline

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Allosteric inhibition of the guanine nucleotide exchange factor DOCK5 by a small molecule von Ferrandez, Yann, Zhang, Wenhua, Peurois, François, Akendengué, Lurlène, Blangy, Anne, Zeghouf, Mahel, Cherfils, Jacqueline

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Pharmacological inhibition of Dock5 prevents osteolysis by affecting osteoclast podosome organization while preserving bone formation von Vives, Virginie, Cres, Gaëlle, Richard, Christian, Busson, Muriel, Ferrandez, Yann, Planson, Anne-Gaelle, Zeghouf, Mahel, Cherfils, Jacqueline, Malaval, Luc, Blangy, Anne

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Structural Organization and Dynamics of Homodimeric Cytohesin Family Arf GTPase Exchange Factors in Solution and on Membranes von Das, Sanchaita, Malaby, Andrew W., Nawrotek, Agata, Zhang, Wenhua, Zeghouf, Mahel, Maslen, Sarah, Skehel, Mark, Chakravarthy, Srinivas, Irving, Thomas C., Bilsel, Osman, Cherfils, Jacqueline, Lambright, David G.

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Nomenclature for the human Arf family of GTP-binding proteins: ARF, ARL, and SAR proteins von Kahn, Richard A, Cherfils, Jacqueline, Elias, Marek, Lovering, Ruth C, Munro, Sean, Schurmann, Annette

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PH-domain-binding inhibitors of nucleotide exchange factor BRAG2 disrupt Arf GTPase signaling von Nawrotek, Agata, Benabdi, Sarah, Niyomchon, Supaporn, Kryszke, Marie-Hélène, Ginestier, Christophe, Cañeque, Tatiana, Tepshi, Livia, Mariani, Angelica, St.Onge, Robert P., Giaever, Guri, Nislow, Corey, Charafe-Jauffret, Emmanuelle, Rodriguez, Raphaël, Zeghouf, Mahel, Cherfils, Jacqueline

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On the explicit use of experimental images in high resolution cryo-EM refinement [version 2; peer review: 2 approved] von Cherfils, Jacqueline, Navaza, Jorge

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EFA6 controls Arf1 and Arf6 activation through a negative feedback loop von Padovani, Dominique, Folly-Klan, Marcia, Labarde, Audrey, Boulakirba, Sonia, Campanacci, Valérie, Franco, Michel, Zeghouf, Mahel, Cherfils, Jacqueline

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