Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4′-Substituted triclosan... von Freundlich, Joel S., Anderson, John W., Sarantakis, Dimitri, Shieh, Hong-Ming, Yu, Min, Valderramos, Juan-Carlos, Lucumi, Edinson, Kuo, Mack, Jacobs, William R., Fidock, David A., Schiehser, Guy A., Jacobus, David P., Sacchettini, James C.

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Synthesis and biological activity of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 2: 2′-Substituted triclosan derivatives von Freundlich, Joel S., Yu, Min, Lucumi, Edinson, Kuo, Mack, Tsai, Han-Chun, Valderramos, Juan-Carlos, Karagyozov, Luchezar, Jacobs, William R., Schiehser, Guy A., Fidock, David A., Jacobus, David P., Sacchettini, James C.

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Phenoxypropoxybiguanides, Prodrugs of DHFR−Inhibiting Diaminotriazine Antimalarials von Jensen, Norman P, Ager, Arba L, Bliss, Robert A, Canfield, Craig J, Kotecka, Barbara M, Rieckmann, Karl H, Terpinski, Jacek, Jacobus, David P

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Novel Saccharomyces cerevisiae Screen Identifies WR99210 Analogues That Inhibit Mycobacterium tuberculosis Dihydrofolate Reductase von GERUM, A'Lissa B, ULMER, Jonathan E, JACOBUS, David P, JENSEN, Norman P, SHERMAN, David R, SIBLEY, Carol Hopkins

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In Vitro Metabolism of Phenoxypropoxybiguanide Analogues in Human Liver Microsomes to Potent Antimalarial Dihydrotriazines von Shearer, Todd. W, Kozar, Michael. P, O'Neil, Michael T, Smith, Philip L, Schiehser, Guy A, Jacobus, David. P, Diaz, Damaris S, Yang, Young-Sun, Milhous, Wilbur. K, Skillman, Donald. R

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Identification of the optimal third generation antifolate against P. falciparum and P. vivax von Hunt, Sonia Y., Detering, Carsten, Varani, Gabriele, Jacobus, David P., Schiehser, Guy A., Shieh, Hong-Ming, Nevchas, Isabelle, Terpinski, Jacek, Sibley, Carol Hopkins

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The antimalarial triazine WR99210 and the prodrug PS-15: folate reversal of in vitro activity against Plasmodium falciparum and a non-antifolate mode of action of the prodrug von Kinyanjui, SM, Mberu, EK, Winstanley, PA, Jacobus, DP, Watkins, WM

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Randomization to Iron Supplementation of Patients with Advanced Human Immunodeficiency Virus Disease—An Inadvertent but Controlled Study with Results Important for Patient Care von Jacobus, David P., Vildé, J. L., Salmon-Céron, D.

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Methaemoglobin formation due to nitrite, disulfiram, 4-aminophenol and monoacetyldapsone hydroxylamine in diabetic and non-diabetic human erythrocytes in vitro von Coleman, Michael D, Hayes, Pamela J, Jacobus, David P

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Anti-Pneumocystis carinii activity of PS-15, a new biguanide folate antagonist von HUGHES, W. T, JACOBUS, D. P, CANFIELD, C, KILLMAR, J

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Failure of Prophylaxis with Dapsone in Patients Taking Dideoxyinosine von Metroka, C E, McMechan, M F, Andrada, R, Laubenstein, L J, Jacobus, D P

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Studies on the differential sensitivity between diabetic and non-diabetic human erythrocytes to monoacetyl dapsone hydroxylamine-mediated methaemoglobin formation in vitro von Coleman, Michael D., Ogg, Malcolm S., Holmes, Jan L., Gardiner, John M., Jacobus, David P.

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Successful treatment and prevention of murine Pneumocystis carinii pneumonitis with 4,4'-sulfonylbisformanilide von Hughes, W T, Smith, B L, Jacobus, D P

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Laboratory evaluation of the phototoxic potency of quinolinemethanols von Rothe, W E, Jacobus, D P

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Synthesis and analgesic activity of 1,3-dihydro-3-(substituted phenyl)imidazo[4,5-b]pyridin-2-ones and 3-(substituted phenyl)-1,2,3-triazolo[4,5-b]pyridines von Clark, Robert L, Pessolano, Arsenio A, Shen, Tsung-Ying, Jacobus, David P, Jones, Howard, Lotti, Victor J, Flataker, Lars M

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Effects of the Germfree State on Responses of Mice to Whole-Body Irradiation von McLaughlin, Mary M., Dacquisto, Michael P., Jacobus, David P., Horowitz, Richard E.

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Potential antiradiation agents. 3. N-substituted aminoethanethiosulfuric acids von Klayman, D L, Grenan, M M, Jacobus, D P

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Direct User Access to the Biological Literature Through Abstracts: A Cooperative Experiment in Customized Service von Jacobus, David P., Gulick, Robert R., Schultz, Louise, Parkins, Phyllis V.

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Response of the DBA/2J Mouse Strain to Acute Ionizing Radiation: The Biphasic Death Pattern von Yuhas, John M., Jacobus, David P., Crenshaw, John W.

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Depression of the isolated guinea pig atrium by β-mercaptoethylamine, β-adrenergic blocking agents, and metabolic inhibitors von Demaree, Gale E., Heiffer, Melvin H., Jacobus, David P., Mundy, Roy L.

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