Design of Protein Multi-specificity Using an Independent Sequence Search Reduces the Barrier to Low Energy Sequences von Sevy, Alexander M, Jacobs, Tim M, Crowe, Jr, James E, Meiler, Jens

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Macromolecular modeling and design in Rosetta: recent methods and frameworks von Leman, Julia Koehler, Weitzner, Brian D., Lewis, Steven M., Adolf-Bryfogle, Jared, Alam, Nawsad, Alford, Rebecca F., Aprahamian, Melanie, Baker, David, Barlow, Kyle A., Basanta, Benjamin, Bender, Brian J., Blacklock, Kristin, Bonet, Jaume, Boyken, Scott E., Bradley, Phil, Bystroff, Chris, Conway, Patrick, Cooper, Seth, Correia, Bruno E., Coventry, Brian, Das, Rhiju, DiMaio, Frank, Dsilva, Lorna, Dunbrack, Roland, Ford, Alexander S., Fu, Darwin Y., Geniesse, Caleb, Goldschmidt, Lukasz, Gowthaman, Ragul, Gray, Jeffrey J., Gront, Dominik, Guffy, Sharon, Huang, Po-Ssu, Jacobs, Tim M., Jeliazkov, Jeliazko R., Johnson, David K., Kappel, Kalli, Karanicolas, John, Khakzad, Hamed, Khar, Karen R., Khare, Sagar D., Khatib, Firas, Khramushin, Alisa, King, Indigo C., Kleffner, Robert, Koepnick, Brian, Kortemme, Tanja, Kuenze, Georg, Kuhlman, Brian, Kuroda, Daisuke, Labonte, Jason W., Lai, Jason K., Lapidoth, Gideon, Leaver-Fay, Andrew, Lindert, Steffen, Linsky, Thomas, London, Nir, Lubin, Joseph H., Lyskov, Sergey, Maguire, Jack, Malmström, Lars, Marcos, Enrique, Marcu, Orly, Marze, Nicholas A., Meiler, Jens, Moretti, Rocco, Mulligan, Vikram Khipple, Nerli, Santrupti, Norn, Christoffer, Ollikainen, Noah, Ovchinnikov, Sergey, Pacella, Michael S., Pan, Xingjie, Park, Hahnbeom, Pavlovicz, Ryan E., Pethe, Manasi, Pilla, Kala Bharath, Raveh, Barak, Renfrew, P. Douglas, Burman, Shourya S. Roy, Rubenstein, Aliza, Sauer, Marion F., Scheck, Andreas, Schief, William, Schueler-Furman, Ora, Sedan, Yuval, Sevy, Alexander M., Sgourakis, Nikolaos G., Shi, Lei, Siegel, Justin B., Silva, Daniel-Adriano, Smith, Shannon, Song, Yifan, Stein, Amelie, Szegedy, Maria, Teets, Frank D., Thyme, Summer B., Wang, Ray Yu-Ruei, Watkins, Andrew, Zimmerman, Lior

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AlphaFold accurately predicts distinct conformations based on the oligomeric state of a de novo designed protein von Cummins, Matthew C., Jacobs, Tim M., Teets, Frank D., DiMaio, Frank, Tripathy, Ashutosh, Kuhlman, Brian

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UbSRD: The Ubiquitin Structural Relational Database von Harrison, Joseph S., Jacobs, Tim M., Houlihan, Kevin, Van Doorslaer, Koenraad, Kuhlman, Brian

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Engineering Polymer‐Binding Bispecific Antibodies for Enhanced Pretargeted Delivery of Nanoparticles to Mucus‐Covered Epithelium von Huckaby, Justin T., Parker, Christina L., Jacobs, Tim M., Schaefer, Alison, Wadsworth, Daniel, Nguyen, Alexander, Wang, Anting, Newby, Jay, Lai, Samuel K.

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Structure of an anti-PEG antibody reveals an open ring that captures highly flexible PEG polymers von Huckaby, Justin T., Jacobs, Tim M., Li, Zhongbo, Perna, Robert J., Wang, Anting, Nicely, Nathan I., Lai, Samuel K.

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Data in support of UbSRD: The Ubiquitin Structural Relational Database von Harrison, Joseph S., Jacobs, Tim M., Houlihan, Kevin, Van Doorslaer, Koenraad, Kuhlman, Brian

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Engineering Polymer‐Binding Bispecific Antibodies for Enhanced Pretargeted Delivery of Nanoparticles to Mucus‐Covered Epithelium von Huckaby, Justin T., Parker, Christina L., Jacobs, Tim M., Schaefer, Alison, Wadsworth, Daniel, Nguyen, Alexander, Wang, Anting, Newby, Jay, Lai, Samuel K.

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Design of Protein Multi-specificity Using an Independent Sequence Search Reduces the Barrier to Low Energy Sequences: e1004300 von Sevy, Alexander M, Jacobs, Tim M, Jr, James ECrowe, Meiler, Jens

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Abstract 1886: Identifying T-cell engagers with optimal potency and cytokine-release profiles with a diverse panel of CD3-binding antibodies von Mai, Juntao (Matt), Caldwell, Kate, DeVorkin, Lindsay, Leung, Grace P., Herve, Karine, Hwang, Yuri, Faralla, Cristina, Wei, Wei, Lathouwers, Emma, Puyraimond, Valentine de, Clifford, Lauren, Chappell, Rhys S., Hannie, Stefan, Lam, Katherine J., Dhupar, Harveer, Tran, Tran N., Cid, Melissa, Bolten, Lena M., Pinsky, Tova, Xiang, Ping, Lai, Courteney, Lee, Ahn, Li, Vivian Z., Chan, Patrick, Chin, Jasmine, Booth, Steve, Lee, Amy C., Masterman, Stephanie, Duncan, Sherie, Yamniuk, Aaron, Dalal, Kush, Jacobs, Tim M., Tonikian, Raffi, Barnhart, Bryan C.

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Abstract 312: Redirecting T cells to tumor targets with functionally diverse CD3-binding antibodies von DeVorkin, Lindsay, Jacobs, Tim M., Tonikian, Raffi, Hervé, Karine, Caldwell, Kate, Hwang, Yuri, Faralla, Cristina, Wei, Wei, Lam, Katherine J., Dhupar, Harveer, Tran, Tran NT, Cid, Melissa, Bolten, Lena M., Pinsky, Tova, Dalal, Kush, Heyries, Kevin A., Barnhart, Bryan C.

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Hemolysis results in impaired intestinal microcirculation and intestinal epithelial cell injury von Hanssen, Sebastiaan J, Lubbers, Tim, Hodin, Caroline M, Prinzen, Frits W, Buurman, Wim A, Jacobs, Michael J

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Metabolic and proteomic indications of diabetes progression in human aqueous humor von Fortenbach, Christopher R, Skeie, Jessica M, Sevcik, Kristina M, Johnson, A Tim, Oetting, Thomas A, Haugsdal, Jaclyn M, Sales, Christopher S, Nishimura, Darryl Y, Taylor, Eric B, Schmidt, Gregory A, Greiner, Mark A

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Faecal Volatile Organic Compounds to Detect Colorectal Neoplasia in Lynch Syndrome—A Prospective Longitudinal Multicentre Study von Liere, Elsa L. S. A., Ramsoekh, Dewkoemar, Daulton, Emma, Dakkak, Maya, Lingen, Joris M., Stewart, Trenton K., Bosch, Sofie, Carvalho, Beatriz, Dekker, Evelien, Jacobs, Maarten A. J. M., Koornstra, Jan Jacob, Kuijvenhoven, Johan P., Leerdam, Monique E., Meij, Tim G. J., Meijer, Gerrit A., Spaander, Manon C. W., Covington, James A., Boer, Nanne K. H.

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Safety and efficacy of riluzole in patients undergoing decompressive surgery for degenerative cervical myelopathy (CSM-Protect): a multicentre, double-blind, placebo-controlled, ra... von Fehlings, Michael G, Badhiwala, Jetan H, Ahn, Henry, Farhadi, H Francis, Shaffrey, Christopher I, Nassr, Ahmad, Mummaneni, Praveen, Arnold, Paul M, Jacobs, W Bradley, Riew, K Daniel, Kelly, Michael, Brodke, Darrel S, Vaccaro, Alexander R, Hilibrand, Alan S, Wilson, Jason, Harrop, James S, Yoon, S Tim, Kim, Kee D, Fourney, Daryl R, Santaguida, Carlo, Massicotte, Eric M, Kopjar, Branko

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Glucose management for exercise using continuous glucose monitoring (CGM) and intermittently scanned CGM (isCGM) systems in type 1 diabetes: position statement of the European Asso... von Moser, Othmar, Riddell, Michael C., Eckstein, Max L., Adolfsson, Peter, Rabasa-Lhoret, Rémi, van den Boom, Louisa, Gillard, Pieter, Nørgaard, Kirsten, Oliver, Nick S., Zaharieva, Dessi P., Battelino, Tadej, de Beaufort, Carine, Bergenstal, Richard M., Buckingham, Bruce, Cengiz, Eda, Deeb, Asma, Heise, Tim, Heller, Simon, Kowalski, Aaron J., Leelarathna, Lalantha, Mathieu, Chantal, Stettler, Christoph, Tauschmann, Martin, Thabit, Hood, Wilmot, Emma G., Sourij, Harald, Smart, Carmel E., Jacobs, Peter G., Bracken, Richard M., Mader, Julia K.

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Simultaneous Presence of Non- and Highly Mutated Keyhole Limpet Hemocyanin (KLH)-Specific Plasmablasts Early after Primary KLH Immunization Suggests Cross-Reactive Memory B Cell Ac... von Giesecke, Claudia, Meyer, Tim, Durek, Pawel, Maul, Jochen, Preiß, Jan, Jacobs, Joannes F M, Thiel, Andreas, Radbruch, Andreas, Ullrich, Reiner, Dörner, Thomas

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Primary cilia mediate mechanosensing in bone cells by a calcium-independent mechanism von Malone, Amanda M.D, Anderson, Charles T, Tummala, Padmaja, Kwon, Ronald Y, Johnston, Tyler R, Stearns, Tim, Jacobs, Christopher R

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Method comparison of four clinically available assays for serum free light chain analysis von Fleming, Chérina K.A., Swarttouw, Tim, de Kat Angelino, Corrie M., Jacobs, Joannes F.M., Russcher, Henk

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Clinically Significant Change in Stroke Volume in Pulmonary Hypertension von van Wolferen, Serge A., MD, van de Veerdonk, Marielle C., BSc, Mauritz, Gert-Jan, BSc, Jacobs, Wouter, MD, Marcus, J. Tim, PhD, Marques, Koen M.J., MD, Bronzwaer, Jean G.F., MD, PhD, Heymans, Martijn W., PhD, Boonstra, Anco, MD, PhD, Postmus, Pieter E., MD, PhD, FCCP, Westerhof, Nico, PhD, Vonk Noordegraaf, Anton, MD, PhD

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