The Ciliary G-Protein-Coupled Receptor Gpr161 Negatively Regulates the Sonic Hedgehog Pathway via cAMP Signaling von Mukhopadhyay, Saikat, Wen, Xiaohui, Ratti, Navneet, Loktev, Alexander, Rangell, Linda, Scales, Suzie J., Jackson, Peter K.

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The primary cilium as a cellular receiver: organizing ciliary GPCR signaling von Hilgendorf, Keren I, Johnson, Carl T, Jackson, Peter K

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Neuropeptide Y Family Receptors Traffic via the Bardet-Biedl Syndrome Pathway to Signal in Neuronal Primary Cilia von Loktev, Alexander V., Jackson, Peter K.

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CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities von Han, Kyuho, Pierce, Sarah E., Li, Amy, Spees, Kaitlyn, Anderson, Gray R., Seoane, Jose A., Lo, Yuan-Hung, Dubreuil, Michael, Olivas, Micah, Kamber, Roarke A., Wainberg, Michael, Kostyrko, Kaja, Kelly, Marcus R., Yousefi, Maryam, Simpkins, Scott W., Yao, David, Lee, Keonil, Kuo, Calvin J., Jackson, Peter K., Sweet-Cordero, Alejandro, Kundaje, Anshul, Gentles, Andrew J., Curtis, Christina, Winslow, Monte M., Bassik, Michael C.

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Ethacridine inhibits SARS-CoV-2 by inactivating viral particles von Li, Xiaoquan, Lidsky, Peter, Xiao, Yinghong, Wu, Chien-Ting, Garcia-Knight, Miguel, Yang, Junjiao, Nakayama, Tsuguhisa, Nayak, Jayakar, Jackson, Peter K., Andino, Raul, Shu, Xiaokun

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Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity von Maurer, Till, Garrenton, Lindsay S, Oh, Angela, Pitts, Keith, Anderson, Daniel J, Skelton, Nicholas J, Fauber, Benjamin P, Pan, Borlan, Malek, Shiva, Stokoe, David, Ludlam, Mary J. C, Bowman, Krista K, Wu, Jiansheng, Giannetti, Anthony M, Starovasnik, Melissa A, Mellman, Ira, Jackson, Peter K, Rudolph, Joachim, Wang, Weiru, Fang, Guowei

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Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation von Lu, Quanlong, Insinna, Christine, Ott, Carolyn, Stauffer, Jimmy, Pintado, Petra A., Rahajeng, Juliati, Baxa, Ulrich, Walia, Vijay, Cuenca, Adrian, Hwang, Yoo-Seok, Daar, Ira O., Lopes, Susana, Lippincott-Schwartz, Jennifer, Jackson, Peter K., Caplan, Steve, Westlake, Christopher J.

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Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition von Boudreau, Aaron, Purkey, Hans E, Hitz, Anna, Robarge, Kirk, Peterson, David, Labadie, Sharada, Kwong, Mandy, Hong, Rebecca, Gao, Min, Del Nagro, Christopher, Pusapati, Raju, Ma, Shuguang, Salphati, Laurent, Pang, Jodie, Zhou, Aihe, Lai, Tommy, Li, Yingjie, Chen, Zhongguo, Wei, Binqing, Yen, Ivana, Sideris, Steve, McCleland, Mark, Firestein, Ron, Corson, Laura, Vanderbilt, Alex, Williams, Simon, Daemen, Anneleen, Belvin, Marcia, Eigenbrot, Charles, Jackson, Peter K, Malek, Shiva, Hatzivassiliou, Georgia, Sampath, Deepak, Evangelista, Marie, O'Brien, Thomas

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Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death von Magnaghi, Paola, D'Alessio, Roberto, Valsasina, Barbara, Avanzi, Nilla, Rizzi, Simona, Asa, Daniela, Gasparri, Fabio, Cozzi, Liviana, Cucchi, Ulisse, Orrenius, Christian, Polucci, Paolo, Ballinari, Dario, Perrera, Claudia, Leone, Antonella, Cervi, Giovanni, Casale, Elena, Xiao, Yang, Wong, Chihunt, Anderson, Daniel J, Galvani, Arturo, Donati, Daniele, O'Brien, Tom, Jackson, Peter K, Isacchi, Antonella

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E2F4 regulates transcriptional activation in mouse embryonic stem cells independently of the RB family von Hsu, Jenny, Arand, Julia, Chaikovsky, Andrea, Mooney, Nancie A., Demeter, Janos, Brison, Caileen M., Oliverio, Romane, Vogel, Hannes, Rubin, Seth M., Jackson, Peter K., Sage, Julien

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Primary cilia on muscle stem cells are critical to maintain regenerative capacity and are lost during aging von Palla, Adelaida R., Hilgendorf, Keren I., Yang, Ann V., Kerr, Jaclyn P., Hinken, Aaron C., Demeter, Janos, Kraft, Peggy, Mooney, Nancie A., Yucel, Nora, Burns, David M., Wang, Yu Xin, Jackson, Peter K., Blau, Helen M.

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Primary cilia membrane assembly is initiated by Rab11 and transport protein particle II (TRAPPII) complex-dependent trafficking of Rabin8 to the centrosome von Westlake, Christopher J, Baye, Lisa M, Nachury, Maxence V, Wright, Kevin J, Ervin, Karen E, Phu, Lilian, Chalouni, Cecile, Beck, John S, Kirkpatrick, Donald S, Slusarski, Diane C, Sheffield, Val C, Scheller, Richard H, Jackson, Peter K

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Nek8 Couples Renal Ciliopathies to DNA Damage and Checkpoint Control von Jackson, Peter K.

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A fast-acting lipid checkpoint in G1 prevents mitotic defects von Köberlin, Marielle S., Fan, Yilin, Liu, Chad, Chung, Mingyu, Pinto, Antonio F. M., Jackson, Peter K., Saghatelian, Alan, Meyer, Tobias

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An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium von Wright, Kevin J, Baye, Lisa M, Olivier-Mason, Anique, Mukhopadhyay, Saikat, Sang, Liyun, Kwong, Mandy, Wang, Weiru, Pretorius, Pamela R, Sheffield, Val C, Sengupta, Piali, Slusarski, Diane C, Jackson, Peter K

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Regulating Microtubules and Genome Stability via the CUL7/3M Syndrome Complex and CUL9 von Jackson, Peter K.

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Tip60-mediated H2A.Z acetylation promotes neuronal fate specification and bivalent gene activation von Janas, Justyna A., Zhang, Lichao, Luu, Jacklyn H., Demeter, Janos, Meng, Lingjun, Marro, Samuele G., Mall, Moritz, Mooney, Nancie A., Schaukowitch, Katie, Ng, Yi Han, Yang, Nan, Huang, Yuhao, Neumayer, Gernot, Gozani, Or, Elias, Joshua E., Jackson, Peter K., Wernig, Marius

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p73 and FoxJ1: Programming Multiciliated Epithelia von Jackson, Peter K, Attardi, Laura D

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Deubiquitinase USP37 Is Activated by CDK2 to Antagonize APCCᴰᴴ¹ and Promote S Phase Entry von Huang, XiaoDong, Summers, Matthew K, Pham, Victoria, Lill, Jennie R, Liu, Jinfeng, Lee, Gwanghee, Kirkpatrick, Donald S, Jackson, Peter K, Fang, Guowei, Dixit, Vishva M

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UHRF1 is a mediator of KRAS driven oncogenesis in lung adenocarcinoma von Kostyrko, Kaja, Román, Marta, Lee, Alex G., Simpson, David R., Dinh, Phuong T., Leung, Stanley G., Marini, Kieren D., Kelly, Marcus R., Broyde, Joshua, Califano, Andrea, Jackson, Peter K., Sweet-Cordero, E. Alejandro

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