Design and Synthesis of a Novel and Potent Series of Inhibitors of Cytosolic Phospholipase A2 Based on a 1,3-Disubstituted Propan-2-one Skeleton von Connolly, Stephen, Bennion, Colin, Botterell, Sarah, Croshaw, Pamela J, Hallam, Catherine, Hardy, Kim, Hartopp, Paul, Jackson, Clive G, King, Sarah J, Lawrence, Louise, Mete, Antonio, Murray, David, Robinson, David H, Smith, Gillian M, Stein, Linda, Walters, Iain, Wells, Edward, Withnall, W. John

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Design of novel and potent cPLA2α inhibitors containing an α-methyl-2-ketothiazole as a metabolically stable serine trap von METE, Antonio, ANDREWS, Glen, ROBINSON, David H, SMITH, Gill M, WELLS, Edward, WITHNALL, W. John, BERNSTEIN, Mike, CONNOLLY, Stephen, HARTOPP, Paul, JACKSON, Clive G, LEWIS, Richard, MARTIN, Lain, MURRAY, David, RILEY, Rob

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Synthesis and evaluation of substrate-mimicking cytosolic phospholipase A2 inhibitors: reducing the lipophilicity of the arachidonyl chain isostere von WALTERS, Lain, BENNION, Colin, MURRAY, David, ROBINSON, David H, STEIN, Linda, WELLS, Edward, WITHNALL, W. John, CONNOLLY, Stephen, CROSHAW, Pamela J, HARDY, Kim, HARTOPP, Paul, JACKSON, Clive G, KING, Sarah J, LAWRENCE, Louise, METE, Antonio

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Monocarboxylate transporter MCT1 is a target for immunosuppression von Murray, Clare M, Hutchinson, Raymond, Bantick, John R, Belfield, Graham P, Benjamin, Amanda D, Brazma, Diana, Bundick, Robert V, Cook, I David, Craggs, Robert I, Edwards, Susan, Evans, Leslie R, Harrison, Richard, Holness, Elain, Jackson, Andrew P, Jackson, Clive G, Kingston, Lee P, Perry, Matthew W D, Ross, Andrew R J, Rugman, Paul A, Sidhu, Sasvinder S, Sullivan, Michael, Taylor-Fishwick, David A, Walker, P Craig, Whitehead, Yvonne M, Wilkinson, David J, Wright, Andrew, Donald, David K

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The regulation by phosphorylation of ‘priming’ of phospholipase A 2 activity in the neutrophil model system, differentiated HL60 cells von Stewart, Allison, Jackson, Clive G., Wakelam, Michael J. O.

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Discovery of new non-phospholipid inhibitors of the secretory phospholipases A2 von Beaton, Haydn G, Bennion, Colin, Connolly, Stephen, Cook, Anthony R, Gensmantel, Nigel P, Hallam, Catherine, Hardy, Kim, Hitchin, Barbara, Jackson, Clive G, Robinson, David H

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The regulation by phosphorylation of ‘priming’ of phospholipase A2 activity in the neutrophil model system, differentiated HL60 cells von Stewart, Allison, Jackson, Clive G., Wakelam, Michael J. O.

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Design and synthesis of some substrate analog inhibitors of phospholipase A2 and investigations by NMR and molecular modeling into the binding interactions in the enzyme-inhibitor... von Bennion, Colin, Connolly, Stephen, Gensmantel, Nigel P, Hallam, Catherine, Jackson, Clive G, Primrose, William U, Roberts, Gordon C. K, Robinson, David H, Slaich, Pritpal K

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Design of novel and potent cPLA sub(2 alpha inhibitors containing an alpha -methyl-2-ketothiazole as a metabolically stable serine trap) von Mete, Antonio, Andrews, Glen, Bernstein, Mike, Connolly, Stephen, Hartopp, Paul, Jackson, Clive G, Lewis, Richard, Martin, Iain, Murray, David, Riley, Rob, Robinson, David H, Smith, Gill M, Wells, Edward, Withnall, WJohn

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Design and synthesis of a novel and potent series of inhibitors of cytosolic phospholipase A(2) based on a 1,3-disubstituted propan-2-one skeleton von Connolly, Stephen, Bennion, Colin, Botterell, Sarah, Croshaw, Pamela J, Hallam, Catherine, Hardy, Kim, Hartopp, Paul, Jackson, Clive G, King, Sarah J, Lawrence, Louise, Mete, Antonio, Murray, David, Robinson, David H, Smith, Gillian M, Stein, Linda, Walters, Iain, Wells, Edward, Withnall, W John

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Design of novel and potent cPLA 2α inhibitors containing an α-methyl-2-ketothiazole as a metabolically stable serine trap von Mete, Antonio, Andrews, Glen, Bernstein, Mike, Connolly, Stephen, Hartopp, Paul, Jackson, Clive G., Lewis, Richard, Martin, Iain, Murray, David, Riley, Rob, Robinson, David H., Smith, Gill M., Wells, Edward, Withnall, W. John

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Synthesis and evaluation of substrate-mimicking cytosolic phospholipase A 2 inhibitors––reducing the lipophilicity of the arachidonyl chain isostere von Walters, Iain, Bennion, Colin, Connolly, Stephen, Croshaw, Pamela J, Hardy, Kim, Hartopp, Paul, Jackson, Clive G, King, Sarah J, Lawrence, Louise, Mete, Antonio, Murray, David, Robinson, David H, Stein, Linda, Wells, Edward, John Withnall, W

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Antigen receptors on immature, but not mature, B and T cells are coupled to cytosolic phospholipase A2 activation: expression and activation of cytosolic phospholipase A2 correlate... von Gilbert, JJ, Stewart, A, Courtney, CA, Fleming, MC, Reid, P, Jackson, CG, Wise, A, Wakelam, MJ, Harnett, MM

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The isolation and purification of the elvapeptins von Bullough, David A., Jackson, Clive G., Henderson, Peter J.F., Beechey, R.Brian, Linnett, Paul E.

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Design and Synthesis of a Novel and Potent Series of Inhibitors of Cytosolic Phospholipase A 2 Based on a 1,3-Disubstituted Propan-2-one Skeleton von Connolly, Stephen, Bennion, Colin, Botterell, Sarah, Croshaw, Pamela J., Hallam, Catherine, Hardy, Kim, Hartopp, Paul, Jackson, Clive G., King, Sarah J., Lawrence, Louise, Mete, Antonio, Murray, David, Robinson, David H., Smith, Gillian M., Stein, Linda, Walters, Iain, Wells, Edward, Withnall, W. John

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pHG165: A pBR322 copy number derivative of pUC8 for cloning and expression von Stewart, Gordon S.A.B., Lubinsky-Mink, Sharon, Jackson, Clive G., Cassel, Aliza, Kuhn, Jonathan

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Bombesin stimulates the rapid activation of phospholipase A2-catalyzed phosphatidylcholine hydrolysis in Swiss 3T3 cells von CURRIE, S, SMITH, G. L, CRICHTON, C. A, JACKSON, C. G, HALLAM, C, WAKELAM, M. J. O

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The isolation and purification of the elvapeptins: A family of peptide inhibitors of mitochondrial ATPase activity von Bullough, David A., Jackson, Clive G., Henderson, Peter J.F., Beechey, R.Brian, Linnett, Paul E.

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Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity von Shepherd, James, Koshy, Cherian, Wise, Emma, Curran, Tanya, Adams, Helen, Moore, Catrin, Khokhar, Fahad A., Reynolds, Nicola, Afifi, Safiah, Price, Anna, Kitchen, Christine, Merrick, Ian, Connor, Thomas R., Bresner, Catherine, Robson, Samuel C., Menegazzo, Mirko, Clark, Gemma, Fleming, Vicki M., Howson-Wells, Hannah C., Bird, Paul, Helmer, Thomas, Fallon, Karlie, du Plessis, Louis, Attwood, Stephen, Vasylyeva, Tetyana, Chaudhry, Yasmin, Moses, Samuel, Ryan, Felicity, Brown, Julianne Rose, Lee, Jack C.D., Alcolea-Medina, Adela, Moore, Nathan, Cortes, Nicholas, Williams, Rebecca, Smith, Darren L., Holmes, Alison, Price, James, Rowan, Aileen, Taylor, Graham P., Watts, Joanne, Ludden, Catherine, George, Ryan P., Li, Kathy K., Carmichael, Stephen N., Johnson, Natasha, Orton, Richard J., Hale, Antony D., Harper, Katherine L., Eltringham, Gary, Coupland, Lindsay J., Barton, Edward, Scott, Garren, Yew, Wen C., Resende Silva, Paola C., Justice, Anita, Chand, Meera, Williams, David, Harrison, Ian, Chalker, Vicki, Heyburn, David, Downing, Fatima, Watkins, Joanne, Howe, Robin, Taylor, Sarah, Wain, John, Rudder, Steven, Gilroy, Rachel A.J., Alikhan, Nabil-Fareed, Casey, Anna, Liggett, Steven, Caller, Laura G., Panchbhaya, Yasmin N., Forrest, Leysa M., Findlay, Jacqueline, Beggs, Andrew, Hesketh, Andrew R., Higginson, Ellen E., Aggarwal, Dinesh, Colquhoun, Rachel, Ashworth, Jordan, McCrone, J.T., Michell, Stephen L., Hughes, Margaret, Rainbow, Lucille, Haldenby, Sam T., Green, Luke R., Parker, Matthew D., Bridgewater, Hannah E., Alam, Mohammad T., Quail, Mike, Thurston, Scott, Beaver, Charlotte, McMinn, Liz, Puethe, Christoph, Tonkin-Hill, Gerry, Smith, Christen, Jamrozy, Dorota, Patel, Minal, Drury, Eleanor, Loman, Nicholas J.

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Aspirin in Patients Undergoing Noncardiac Surgery von Devereaux, P.J, Mrkobrada, Marko, Sessler, Daniel I, Leslie, Kate, Alonso-Coello, Pablo, Kurz, Andrea, Villar, Juan Carlos, Sigamani, Alben, Biccard, Bruce M, Meyhoff, Christian S, Parlow, Joel L, Guyatt, Gordon, Robinson, Andrea, Garg, Amit X, Rodseth, Reitze N, Botto, Fernando, Lurati Buse, Giovanna, Xavier, Denis, Chan, Matthew T.V, Tiboni, Maria, Cook, Deborah, Kumar, Priya A, Forget, Patrice, Malaga, German, Fleischmann, Edith, Amir, Mohammed, Eikelboom, John, Mizera, Richard, Torres, David, Wang, C.Y, VanHelder, Tomas, Paniagua, Pilar, Berwanger, Otavio, Srinathan, Sadeesh, Graham, Michelle, Pasin, Laura, Le Manach, Yannick, Gao, Peggy, Pogue, Janice, Whitlock, Richard, Lamy, André, Kearon, Clive, Baigent, Colin, Chow, Clara, Pettit, Shirley, Chrolavicius, Susan, Yusuf, Salim

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