Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application von Jackson, Aimee L, Linsley, Peter S

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Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity von Jackson, Aimee L, Burchard, Julja, Schelter, Janell, Chau, B Nelson, Cleary, Michele, Lim, Lee, Linsley, Peter S

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MicroRNAs in the miR-106b Family Regulate p21/CDKN1A and Promote Cell Cycle Progression von Ivanovska, Irena, Ball, Alexey S., Diaz, Robert L., Magnus, Jill F., Kibukawa, Miho, Schelter, Janell M., Kobayashi, Sumire V., Lim, Lee, Burchard, Julja, Jackson, Aimee L., Linsley, Peter S., Cleary, Michele A.

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Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing von Jackson, Aimee L, Burchard, Julja, Leake, Devin, Reynolds, Angela, Schelter, Janell, Guo, Jie, Johnson, Jason M, Lim, Lee, Karpilow, Jon, Nichols, Kim, Marshall, William, Khvorova, Anastasia, Linsley, Peter S

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Noise amidst the silence: off-target effects of siRNAs? von Jackson, Aimee L., Linsley, Peter S.

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Coordinated regulation of cell cycle transcripts by p53-Inducible microRNAs, miR-192 and miR-215 von Georges, Sara A, Biery, Matthew C, Kim, Soo-Yeon, Schelter, Janell M, Guo, Jane, Chang, Aaron N, Jackson, Aimee L, Carleton, Michael O, Linsley, Peter S, Cleary, Michele A, Chau, B Nelson

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Transcripts Targeted by the MicroRNA-16 Family Cooperatively Regulate Cell Cycle Progression von Linsley, Peter S., Schelter, Janell, Burchard, Julja, Kibukawa, Miho, Martin, Melissa M., Bartz, Steven R., Johnson, Jason M., Cummins, Jordan M., Raymond, Christopher K., Dai, Hongyue, Chau, Nelson, Cleary, Michele, Jackson, Aimee L., Carleton, Michael, Lim, Lee

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Genome-scale RNAi profiling of cell division in human tissue culture cells von Wagner, Jan, Kozak, Karol, Kittler, Ralf, Richter, Constance, Pelletier, Laurence, Surendranath, Vineeth, Hyman, Anthony A, Miroslaw, Lukasz, Lawo, Steffen, Bowen, Wayne, Jackson, Aimee L, Heninger, Anne-Kristine, Theis, Mirko, Poser, Ina, Buchholz, Frank, Grabner, Hannes, Habermann, Bianca, Slabicki, Mikolaj

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Minimizing the risk of reporting false positives in large-scale RNAi screens von Echeverri, Christophe J, Beachy, Philip A, Baum, Buzz, Boutros, Michael, Buchholz, Frank, Chanda, Sumit K, Downward, Julian, Ellenberg, Jan, Fraser, Andrew G, Hacohen, Nir, Hahn, William C, Jackson, Aimee L, Kiger, Amy, Linsley, Peter S, Lum, Lawrence, Ma, Yong, Mathey-Prévôt, Bernard, Root, David E, Sabatini, David M, Taipale, Jussi, Perrimon, Norbert, Bernards, René

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Developing microRNA Therapeutics: Approaching the Unique Complexities von Jackson, Aimee L., Levin, Arthur A.

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Cobomarsen, an oligonucleotide inhibitor of miR‐155, co‐ordinately regulates multiple survival pathways to reduce cellular proliferation and survival in cutaneous T‐cell lymphoma... von Seto, Anita G., Beatty, Xuan, Lynch, Joshua M., Hermreck, Melanie, Tetzlaff, Michael, Duvic, Madeleine, Jackson, Aimee L.

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Small Interfering RNA Screens Reveal Enhanced Cisplatin Cytotoxicity in Tumor Cells Having both BRCA Network and TP53 Disruptions von Bartz, Steven R., Zhang, Zhan, Burchard, Julja, Imakura, Maki, Martin, Melissa, Palmieri, Anthony, Needham, Rachel, Guo, Jie, Gordon, Marcia, Chung, Namjin, Warrener, Paul, Jackson, Aimee L., Carleton, Michael, Oatley, Melissa, Locco, Louis, Santini, Francesca, Smith, Todd, Kunapuli, Priya, Ferrer, Marc, Strulovici, Berta, Friend, Stephen H., Linsley, Peter S.

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A MicroRNA-29 Mimic (Remlarsen) Represses Extracellular Matrix Expression and Fibroplasia in the Skin von Gallant-Behm, Corrie L., Piper, Joseph, Lynch, Joshua M., Seto, Anita G., Hong, Seok Jong, Mustoe, Thomas A., Maari, Catherine, Pestano, Linda A., Dalby, Christina M., Jackson, Aimee L., Rubin, Paul, Marshall, William S.

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Gene expression profiling following NRF2 and KEAP1 siRNA knockdown in human lung fibroblasts identifies CCL11/Eotaxin-1 as a novel NRF2 regulated gene von Fourtounis, Jimmy, Wang, I-Ming, Mathieu, Marie-Claude, Claveau, David, Loo, Tenneille, Jackson, Aimee L, Peters, Mette A, Therien, Alex G, Boie, Yves, Crackower, Michael A

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MicroRNA-like off-target transcript regulation by siRNAs is species specific von Burchard, Julja, Jackson, Aimee L, Malkov, Vladislav, Needham, Rachel H V, Tan, Yejun, Bartz, Steven R, Dai, Hongyue, Sachs, Alan B, Linsley, Peter S

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Cobomarsen, an Oligonucleotide Inhibitor of miR-155, Slows DLBCL Tumor Cell Growth In Vitro and In Vivo von Anastasiadou, Eleni, Seto, Anita G., Beatty, Xuan, Hermreck, Melanie, Gilles, Maud-Emmanuelle, Stroopinsky, Dina, Pinter-Brown, Lauren C., Pestano, Linda, Marchese, Cinzia, Avigan, David, Trivedi, Pankaj, Escolar, Diana M., Jackson, Aimee L., Slack, Frank J.

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A synthetic microRNA-92a inhibitor (MRG-110) accelerates angiogenesis and wound healing in diabetic and nondiabetic wounds von Gallant-Behm, Corrie L, Piper, Joseph, Dickinson, Brent A, Dalby, Christina M, Pestano, Linda A, Jackson, Aimee L

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A microRNA component of the p53 tumour suppressor network von Cleary, Michele A, Hannon, Gregory J, He, Lin, He, Xingyue, Lim, Lee P, de Stanchina, Elisa, Xuan, Zhenyu, Liang, Yu, Xue, Wen, Zender, Lars, Magnus, Jill, Ridzon, Dana, Jackson, Aimee L, Linsley, Peter S, Chen, Caifu, Lowe, Scott W

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Induction of Microsatellite Instability by Oxidative DNA Damage von Jackson, Aimee L., Chen, Ru, Loeb, Lawrence A.

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The Mutation Rate and Cancer von Jackson, Aimee L, Loeb, Lawrence A

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