Discovery of Novel STING Inhibitors Based on the Structure of the Mouse STING Agonist DMXAA von Chang, Jiajia, Hou, Shi, Yan, Xinlin, Li, Wei, Xiao, Junhai

Volltext

Phencynonate S-isomer as a eutomer is a novel central anticholinergic drug for anti-motion sickness von Xu, Pingxiang, Liu, Ying, Wang, Liyun, Wu, Yi, Zhou, Xuelin, Xiao, Junhai, Zheng, Jianquan, Xue, Ming

Volltext

Design, Synthesis, Bioactivity Evaluation, Crystal Structures, and In Silico Studies of New α-Amino Amide Derivatives as Potential Histone Deacetylase 6 Inhibitors von Xu, Yangrong, Tang, Hangjun, Xu, Yijie, Guo, Jialin, Zhao, Xu, Meng, Qingguo, Xiao, Junhai

Volltext

Design, Synthesis, and Biological Evaluation of the Quorum-Sensing Inhibitors of Pseudomonas aeruginosa PAO1 von Yan, Xinlin, Hou, Shi, Xing, Cheng, Zhang, Yuanyuan, Chang, Jiajia, Xiao, Junhai, Lin, Feng

Volltext

Design, Synthesis, and Renal Targeting of Methylprednisolone-Lysozyme von Pan, Xingquan, Xie, Fei, Xiao, Dian, Zhou, Xinbo, Xiao, Junhai

Volltext

Design, Synthesis, and Structure–Activity Relationship Study of Epoxysuccinyl–Peptide Derivatives as Cathepsin B Inhibitors von Zhang, Xiaoye, Yang, Xiaohong, Wang, Hongqiang, Li, Song, Guo, Kun, Jiang, Dan, Xiao, Junhai, Liang, Di

Volltext

Phenoxyaromatic Acid Analogues as Novel Radiotherapy Sensitizers: Design, Synthesis and Biological Evaluation von Zhang, Hongquan, Wen, Chunxi, Li, Bingting, Yan, Xinlin, Xu, Yangrong, Guo, Jialin, Hou, Shi, Chang, Jiajia, Li, Song, Xiao, Junhai

Volltext

Chlorotheolides A and B, Spiroketals Generated via Diels–Alder Reactions in the Endophytic Fungus Pestalotiopsis theae von Liu, Ling, Han, Yu, Xiao, Junhai, Li, Li, Guo, Liangdong, Jiang, Xuejun, Kong, Lingyi, Che, Yongsheng

Volltext

Effect of Autoinducer-2 Quorum Sensing Inhibitor on Interspecies Quorum Sensing von Jiang, Kai, Xu, Yijie, Yuan, Bo, Yue, Yuandong, Zhao, Meihua, Luo, Rui, Wu, Hao, Wang, Lei, Zhang, Yuanyuan, Xiao, Junhai, Lin, Feng

Volltext

Discovery of AI-2 Quorum Sensing Inhibitors Targeting the LsrK/HPr Protein-Protein Interaction Site by Molecular Dynamics Simulation, Virtual Screening, and Bioassay Evaluation von Xu, Yijie, Zeng, Chunlan, Wen, Huiqi, Shi, Qianqian, Zhao, Xu, Meng, Qingbin, Li, Xingzhou, Xiao, Junhai

Volltext

Novel potent molecular glue degraders against broad range of hematological cancer cell lines via multiple neosubstrates degradation von Li, Pengyun, Hu, Xiaotong, Fan, Zhiya, Sun, Shiyang, Ran, Qijie, Wei, Ting, Wei, Pengli, Jiang, Qiyu, Yan, Jian, Yang, Ning, Jia, Changkai, Yang, Tingting, Mao, Yaqiu, Cai, Xu, Xu, Tingting, Zhao, Zhiyuan, Qian, Xiaohong, Qin, Weijie, Zhuang, Xiaomei, Fan, Feng, Xiao, Junhai, Zheng, Zhibing, Li, Song

Volltext

Discovery of novel exceptionally potent and orally active c-MET PROTACs for the treatment of tumors with MET alterations von Li, Pengyun, Jia, Changkai, Fan, Zhiya, Hu, Xiaotong, Zhang, Wenjuan, Liu, Ke, Sun, Shiyang, Guo, Haoxin, Yang, Ning, Zhu, Maoxiang, Zhuang, Xiaomei, Xiao, Junhai, Zheng, Zhibing, Li, Song

Volltext

Virtual screening-based discovery of AI-2 quorum sensing inhibitors that interact with an allosteric hydrophobic site of LsrK and their functional evaluation von Shi, Qianqian, Wen, Huiqi, Xu, Yijie, Zhao, Xu, Zhang, Jing, Li, Ye, Meng, Qingbin, Yu, Fang, Xiao, Junhai, Li, Xingzhou

Volltext

Beclin 1-independent autophagy induced by a Bcl-XL/Bcl-2 targeting compound, Z18 von Tian, Songhai, Lin, Jian, Zhou, Jun, Wang, Xiaolong, Li, Yanjun, Ren, Xiaobai, Yu, Wenyu, Zhong, Wu, Xiao, Junhai, Sheng, Fugeng, Chen, Yingyu, Jin, Changwen, Li, Song, Zheng, Zhibing, Xia, Bin

Volltext

Design, synthesis and biological evaluation of N-sulfonyl homoserine lactone derivatives as inhibitors of quorum sensing in Chromobacterium violaceum von Zhao, Mingming, Yu, Yingying, Hua, Yuhui, Feng, Fan, Tong, Yigang, Yang, Xiaohong, Xiao, Junhai, Song, Hongrui

Volltext

Design and synthesis of a series of pyrido[2,3-d]pyrimidine derivatives as CCR4 antagonists von Gong, Hongwei, Qi, Hui, Sun, Wei, Zhang, Yang, Jiang, Dan, Xiao, Junhai, Yang, Xiaohong, Wang, Ying, Li, Song

Volltext

Design, synthesis and SAR study of novel trisubstituted pyrimidine amide derivatives as CCR4 antagonists von Xu, Libao, Zhang, Yang, Dai, Wenjie, Wang, Ying, Jiang, Dan, Wang, Lili, Xiao, Junhai, Yang, Xiaohong, Li, Song

Volltext

Novel substituted heteroaromatic piperazine and piperidine derivatives as inhibitors of human enterovirus 71 and coxsackievirus a16 von Zhang, Xian, Wang, Hongliang, Li, Yuhuan, Cao, Ruiyuan, Zhong, Wu, Zheng, Zhibing, Wang, Gang, Xiao, Junhai, Li, Song

Volltext

Nanocellulose aerogel prepared using discarded cotton textiles: For constructing water evaporation and self-cooling thermoelectric systems von Xiao, Junhai, Wu, Fucai, Hu, Chunyan, Zhu, Zhijia, Liu, Baojiang

Volltext

Synthesis and biological evaluation of 1,2,4-trisubstituted imidazoles and 1,3,5-trisubstituted pyrazoles as inhibitors of transforming growth factor β type 1 receptor (ALK5) von Li, Xingzhou, Wang, Lili, Long, Long, Xiao, Junhai, Hu, Yuandong, Li, Song

Volltext