NADPH oxidase 1 supports proliferation of colon cancer cells by modulating reactive oxygen species-dependent signal transduction von Juhasz, Agnes, Markel, Susan, Gaur, Shikha, Liu, Han, Lu, Jiamo, Jiang, Guojian, Wu, Xiwei, Antony, Smitha, Wu, Yongzhong, Melillo, Giovanni, Meitzler, Jennifer L., Haines, Diana C., Butcher, Donna, Roy, Krishnendu, Doroshow, James H.

Volltext

NADPH oxidase 1 is highly expressed in human large and small bowel cancers von Lu, Jiamo, Jiang, Guojian, Wu, Yongzhong, Antony, Smitha, Meitzler, Jennifer L, Juhasz, Agnes, Liu, Han, Roy, Krishnendu, Makhlouf, Hala, Chuaqui, Rodrigo, Butcher, Donna, Konaté, Mariam M, Doroshow, James H

Volltext

Decoding NADPH oxidase 4 expression in human tumors von Meitzler, Jennifer L., Makhlouf, Hala R., Antony, Smitha, Wu, Yongzhong, Butcher, Donna, Jiang, Guojian, Juhasz, Agnes, Lu, Jiamo, Dahan, Iris, Jansen-Dürr, Pidder, Pircher, Haymo, Shah, Ajay M., Roy, Krishnendu, Doroshow, James H.

Volltext

Characterization of potent and selective iodonium-class inhibitors of NADPH oxidases von Lu, Jiamo, Risbood, Prabhakar, Kane, Charles T., Hossain, Md Tafazzal, Anderson, Larry, Hill, Kimberly, Monks, Anne, Wu, Yongzhong, Antony, Smitha, Juhasz, Agnes, Liu, Han, Jiang, Guojian, Harris, Erik, Roy, Krishnendu, Meitzler, Jennifer L., Konaté, Mariam, Doroshow, James H.

Volltext

The novel histone deacetylase inhibitor, LBH589, induces expression of DNA damage response genes and apoptosis in Ph− acute lymphoblastic leukemia cells von Scuto, Anna, Kirschbaum, Mark, Kowolik, Claudia, Kretzner, Leo, Juhasz, Agnes, Atadja, Peter, Pullarkat, Vinod, Bhatia, Ravi, Forman, Stephen, Yen, Yun, Jove, Richard

Volltext

Kinetics of Exhaled Carbon Monoxide After Water-pipe Smoking Indoors and Outdoors von Juhasz, Agnes, MD, Pap, Dalma, MD, Barta, Imre, PhD, Drozdovszky, Orsolya, MSc, Egresi, Andrea, PhD, Antus, Balazs, MD, DSc

Volltext

Antiproliferative mechanisms of action of the flavin dehydrogenase inhibitors diphenylene iodonium and di-2-thienyliodonium based on molecular profiling of the NCI-60 human tumor c... von Doroshow, James H., Juhasz, Agnes, Ge, Yun, Holbeck, Susan, Lu, Jiamo, Antony, Smitha, Wu, Yongzhong, Jiang, Guojian, Roy, Krishnendu

Volltext

Human Papillomavirus Infection as a Prognostic Factor in Oropharyngeal Squamous Cell Carcinomas Treated in a Prospective Phase II Clinical Trial von JO, Solomon, JUHASZ, Agnes, PAZ, Benjamin, SOMLO, George, VORA, Nayana, SHIBATA, Stephen, KEQIANG ZHANG, RUEL, Christopher, LOERA, Sofia, WILCZYNSKI, Sharon P, YUN YEN, XIYONG LIU, ELLENHORN, Joshua, LIM, Dean

Volltext

A phase II study of the antisense oligonucleotide GTI-2040 plus docetaxel and prednisone as first-line treatment in castration-resistant prostate cancer von Sridhar, Srikala S., Canil, Christina M., Chi, Kim N., Hotte, Sebastien J., Ernst, Scott, Wang, Lisa, Chen, Eric X., Juhasz, Agnes, Yen, Yun, Murray, Peter, Zwiebel, James A., Moore, Malcolm J.

Volltext

NADPH oxidases: a perspective on reactive oxygen species production in tumor biology von Meitzler, Jennifer L, Antony, Smitha, Wu, Yongzhong, Juhasz, Agnes, Liu, Han, Jiang, Guojian, Lu, Jiamo, Roy, Krishnendu, Doroshow, James H

Volltext

Exogenous DNA enhances DUOX2 expression and function in human pancreatic cancer cells by activating the cGAS-STING signaling pathway von Wang, Stephen L., Wu, Yongzhong, Konaté, Mariam, Lu, Jiamo, Mallick, David, Antony, Smitha, Meitzler, Jennifer L., Jiang, Guojian, Dahan, Iris, Juhasz, Agnes, Diebold, Becky, Roy, Krishnendu, Doroshow, James H.

Volltext

Interleukin-4 and interleukin-13 increase NADPH oxidase 1-related proliferation of human colon cancer cells von Liu, Han, Antony, Smitha, Roy, Krishnendu, Juhasz, Agnes, Wu, Yongzhong, Lu, Jiamo, Meitzler, Jennifer L, Jiang, Guojian, Polley, Eric, Doroshow, James H

Volltext

IL-4 and IL-17A Cooperatively Promote Hydrogen Peroxide Production, Oxidative DNA Damage, and Upregulation of Dual Oxidase 2 in Human Colon and Pancreatic Cancer Cells von Wu, Yongzhong, Konaté, Mariam M, Lu, Jiamo, Makhlouf, Hala, Chuaqui, Rodrigo, Antony, Smitha, Meitzler, Jennifer L, Difilippantonio, Michael J, Liu, Han, Juhasz, Agnes, Jiang, Guojian, Dahan, Iris, Roy, Krishnendu, Doroshow, James H

Volltext

Abstract 514: DUOX2-related H2O2 production contributes to pro-inflammatory cytokine-related DNA damage and tumor cell growth in models of pancreatic ductal adenocarcinoma von Wu, Yongzhong, Lu, Jiamo, Antony, Smitha, Meitzler, Jennifer L., Juhasz, Agnes, Jiang, Guojian, Dahan, Iris, Doroshow, James H.

Volltext

Abstract 3348: Exogenous DNA upregulates DUOX2 expression in pancreatic cancer via activation of the cGAS-STING signaling pathway von Wang, Stephen L., Wu, Yongzhong, Antony, Smitha, Juhasz, Agnes, Meitzler, Jennifer, Jiang, Goujian, Dahan, Iris, Lu, Jiamo, Roy, Krishnendu, Doroshow, James

Volltext

Abstract 3571: Oxidative stress and the ovarian surface epithelium: TGF-β1 stimulation of IOSE cell lines reveals novel upregulation of NADPH oxidase 4, a membrane bound hydrogen p... von Meitzler, Jennifer L., Diebold, Becky A., Antony, Smitha, Wu, Yongzhong, Juhasz, Agnes, Dahan, Iris, Jiang, Guojian, Lu, Jiamo, Wang, Stephen, Konaté, Mariam M., Roy, Krishnendu, Doroshow, James H.

Volltext

Up-regulation and Sustained Activation of Stat1 Are Essential for Interferon-γ (IFN-γ)-induced Dual Oxidase 2 (Duox2) and Dual Oxidase A2 (DuoxA2) Expression in Human Pancreatic Ca... von Wu, Yongzhong, Antony, Smitha, Juhasz, Agnes, Lu, Jiamo, Ge, Yun, Jiang, Guojian, Roy, Krishnendu, Doroshow, James H.

Volltext

Abstract 2915: Synergistic, cytokine mediated stimulation (IL-1α/β + IL-6) of colon cancer cells reveals a novel mechanism of DNA damage facilitated by up-regulation of NOX1 and DU... von Meitzler, Jennifer L., Wu, Yongzhong, Juhasz, Agnes, Rapisarda, Annamaria, Campbell, Petreena, Diebold, Becky A., Antony, Smitha, Jiang, Guojian, Lu, Jiamo, Mallick, David J., Konaté, Mariam M., Roy, Krishnendu, Doroshow, James H.

Volltext

Abstract 876: CD40-induced growth inhibition of Burkitt lymphoma: A possible role for NADPH oxidase by upregulation of p67phox von Dahan, Mazal Iris, Antony, Smitha, Juhasz, Agnes, Jiang, Guojian, Konate, Mariam, Lu, Jiamo, Meitzler, Jennifer, Wu, YongZhong, Roy, Krishnendu, Doroshow, James H.

Volltext

Activation of TLR4 is required for the synergistic induction of dual oxidase 2 and dual oxidase A2 by IFN-γ and lipopolysaccharide in human pancreatic cancer cell lines von Wu, Yongzhong, Lu, Jiamo, Antony, Smitha, Juhasz, Agnes, Liu, Han, Jiang, Guojian, Meitzler, Jennifer L, Hollingshead, Melinda, Haines, Diana C, Butcher, Donna, Roy, Krishnendu, Doroshow, James H

Volltext