Confirming the RNAi-mediated mechanism of action of siRNA-based cancer therapeutics in mice von Judge, Adam D, Robbins, Marjorie, Tavakoli, Iran, Levi, Jasna, Hu, Lina, Fronda, Anna, Ambegia, Ellen, McClintock, Kevin, MacLachlan, Ian

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Overcoming the Innate Immune Response to Small Interfering RNA von JUDGE, Adam, MACLACHLAN, Ian

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Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA von MacLachlan, Ian, Judge, Adam D, Sood, Vandana, Shaw, Janet R, Fang, Dianne, McClintock, Kevin

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Antitumor Effects in Hepatocarcinoma of Isoform-Selective Inhibition of HDAC2 von LEE, Yun-Han, DAEKWAN SEO, CONNER, Elizabeth A, MACLACHLAN, Ian, FACTOR, Valentina M, THORGEIRSSON, Snorri S, CHOI, Kyung-Ju, ANDERSEN, Jesper B, WON, Min-Ah, KITADE, Mitsuteru, GOMEZ-QUIROZ, Luis E, JUDGE, Adam D, MARQUARDT, Jens U, RAGGI, Chiara

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Design of noninflammatory synthetic siRNA mediating potent gene silencing in vivo von Judge, Adam D, Bola, Gurneet, Lee, Amy C H, MacLachlan, Ian

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Postexposure protection of non-human primates against a lethal Ebola virus challenge with RNA interference: a proof-of-concept study von Geisbert, Thomas W, Prof, Lee, Amy CH, MSc, Robbins, Marjorie, PhD, Geisbert, Joan B, Honko, Anna N, PhD, Sood, Vandana, MSc, Johnson, Joshua C, BSc, de Jong, Susan, PhD, Tavakoli, Iran, BSc, Judge, Adam, PhD, Hensley, Lisa E, PhD, MacLachlan, Ian, PhD

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Hypersensitivity and Loss of Disease Site Targeting Caused by Antibody Responses to PEGylated Liposomes von Judge, Adam, McClintock, Kevin, Phelps, Janet R, Maclachlan, Ian

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Misinterpreting the Therapeutic Effects of Small Interfering RNA Caused by Immune Stimulation von ROBBINS, Marjorie, JUDGE, Adam, AMBEGIA, Ellen, CHOI, Catherine, YAWORSKI, Ed, PALMER, Lorne, MCCLINTOCK, Kevin, MACLACHLAN, Ian

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Definition of Ubiquitination Modulator COP1 as a Novel Therapeutic Target in Human Hepatocellular Carcinoma von LEE, Yun-Han, ANDERSEN, Jesper B, HYUN GOO WOO, CONNER, Elizabeth A, AVITAL, Itzhak, MACLACHLAN, Ian, FACTOR, Valentina M, THORGEIRSSON, Snorri S, SONG, Ho-Taek, JUDGE, Adam D, SEO, Daekwan, ISHIKAWA, Tsuyoshi, MARQUARDT, Jens U, KITADE, Mitsuteru, DURKIN, Marian E, RAGGI, Chiara

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Interleukin 15 controls both proliferation and survival of a subset of memory-phenotype CD8(+) T cells von Judge, Adam D, Zhang, Xiaohong, Fujii, Hideki, Surh, Charles D, Sprent, Jonathan

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Postexposure Protection of Guinea Pigs against a Lethal Ebola Virus Challenge Is Conferred by RNA Interference von Geisbert, Thomas W., Hensley, Lisa E., Kagan, Elliott, Yu, Erik Zhaoying, Geisbert, Joan B., Daddario-DiCaprio, Kathleen, Fritz, Elizabeth A., Jahrling, Peter B., McClintock, Kevin, Phelps, Janet R., Lee, Amy C. H., Judge, Adam, Jeffs, Lloyd B., MacLachlan, Ian

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RNAi-mediated gene silencing in non-human primates von Wheat, Amanda J, Vornlocher, Hans-Peter, Röhl, Ingo, Lam, Kieu, McClintock, Kevin, Koteliansky, Victor, Yaworski, Ed, Jeffs, Lloyd B, MacLachlan, Ian, Soutschek, Jürgen, Toudjarska, Ivanka, Palmer, Lorne R, Heyes, James A, Zedalis, William, Akinc, Akin, Lee, Amy C. H, Bumcrot, David, Manoharan, Muthiah, Judge, Adam D, Racie, Timothy, Shanmugam, Sumi, Sood, Vandana, Seiffert, Stephan, Bramlage, Birgit, Fedoruk, Matthew N, Harborth, Jens, Zimmermann, Tracy S, John, Matthias, Nechev, Lubomir V

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CD4 T cell traffic control: in vivo evidence that ligation of OX40 on CD4 T cells by OX40‐ligand expressed on dendritic cells leads to the accumulation of CD4 T cells in B follicle... von Brocker, Thomas, Gulbranson‐Judge, Adam, Flynn, Sarah, Riedinger, Mireille, Raykundalia, Chandra, Lane, Peter

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2′-O-methyl-modified RNAs Act as TLR7 Antagonists von Robbins, Marjorie, Judge, Adam, Liang, Lisa, McClintock, Kevin, Yaworski, Ed, MacLachlan, Ian

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The changing preference of T and B cells for partners as T-dependent antibody responses develop von MacLennan, Ian C. M., Gulbranson-Judge, Adam, Toellner, Kai-Michael, Casamayor-Palleja, Montserrat, Sze, Daniel M -Y., Chan, Eric Y-T, Luther, Sanjiv A., Orbea, Hans Acha

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Minimal-length Synthetic shRNAs Formulated with Lipid Nanoparticles are Potent Inhibitors of Hepatitis C Virus IRES-linked Gene Expression in Mice von Dallas, Anne, Ilves, Heini, Shorenstein, Joshua, Judge, Adam, Spitler, Ryan, Contag, Christopher, Wong, Suet Ping, Harbottle, Richard P, MacLachlan, Ian, Johnston, Brian H

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Dendritic cells associated with plasmablast survival von García de Vinuesa, Carola, Gulbranson‐Judge, Adam, Khan, Mahmood, O'Leary, Paula, Cascalho, Marilia, Wabl, Matthias, Klaus, Gerry G. B., Owen, Michael J., MacLennan, Ian C. M.

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Sequential antigen‐specific growth of T cells in the T zones and follicles in response to pigeon cytochrome c von Gulbranson‐Judge, Adam, Maclennan, Ian

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Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs von Morrissey, David V, Lockridge, Jennifer A, Shaw, Lucinda, Blanchard, Karin, Jensen, Kristi, Breen, Wendy, Hartsough, Kimberly, Machemer, Lynn, Radka, Susan, Jadhav, Vasant, Vaish, Narendra, Zinnen, Shawn, Vargeese, Chandra, Bowman, Keith, Shaffer, Chris S, Jeffs, Lloyd B, Judge, Adam, MacLachlan, Ian, Polisky, Barry

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Abstract 2829: Preclinical characterization of TKM-080301, a lipid nanoparticle formulation of a small interfering RNA directed against polo-like kinase 1 von Semple, Sean C., Judge, Adam D., Robbins, Marjorie, Klimuk, Sandra, Eisenhardt, Merete, Crosley, Erin, Leung, Ada, Kwok, Raymond, Ambegia, Ellen, McClintock, Kevin, MacLachlan, Ian

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