PARPi Triggers the STING-Dependent Immune Response and Enhances the Therapeutic Efficacy of Immune Checkpoint Blockade Independent of BRCAness von Shen, Jianfeng, Zhao, Wei, Ju, Zhenlin, Wang, Lulu, Peng, Yang, Labrie, Marilyne, Yap, Timothy A, Mills, Gordon B, Peng, Guang

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Clinical relevance of TP53 hotspot mutations in high-grade serous ovarian cancers von Tuna, Musaffe, Ju, Zhenlin, Yoshihara, Kosuke, Amos, Christopher I., Tanyi, Janos L., Mills, Gordon B.

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ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade von Shen, Jianfeng, Ju, Zhenlin, Zhao, Wei, Wang, Lulu, Peng, Yang, Ge, Zhongqi, Nagel, Zachary D., Zou, Jun, Wang, Chen, Kapoor, Prabodh, Ma, Xiangyi, Ma, Ding, Liang, Jiyong, Song, Shumei, Liu, Jinsong, Samson, Leona D., Ajani, Jaffer A., Li, Guo-Min, Liang, Han, Shen, Xuetong, Mills, Gordon B., Peng, Guang

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TCPA: a resource for cancer functional proteomics data von Li, Jun, Lu, Yiling, Akbani, Rehan, Ju, Zhenlin, Roebuck, Paul L, Liu, Wenbin, Yang, Ji-Yeon, Broom, Bradley M, Verhaak, Roeland G W, Kane, David W, Wakefield, Chris, Weinstein, John N, Mills, Gordon B, Liang, Han

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Immuno-genomic landscape of osteosarcoma von Wu, Chia-Chin, Beird, Hannah C., Andrew Livingston, J., Advani, Shailesh, Mitra, Akash, Cao, Shaolong, Reuben, Alexandre, Ingram, Davis, Wang, Wei-Lien, Ju, Zhenlin, Hong Leung, Cheuk, Lin, Heather, Zheng, Youyun, Roszik, Jason, Wang, Wenyi, Patel, Shreyaskumar, Benjamin, Robert S., Somaiah, Neeta, Conley, Anthony P., Mills, Gordon B., Hwu, Patrick, Gorlick, Richard, Lazar, Alexander, Daw, Najat C., Lewis, Valerae, Futreal, P. Andrew

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ARID1A Deficiency Impairs the DNA Damage Checkpoint and Sensitizes Cells to PARP Inhibitors von Shen, Jianfeng, Peng, Yang, Wei, Leizhen, Zhang, Wei, Yang, Lin, Lan, Li, Kapoor, Prabodh, Ju, Zhenlin, Mo, Qianxing, Shih, Ie-Ming, Uray, Ivan P, Wu, Xiangwei, Brown, Powel H, Shen, Xuetong, Mills, Gordon B, Peng, Guang

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The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers von Han, Leng, Diao, Lixia, Yu, Shuangxing, Xu, Xiaoyan, Li, Jie, Zhang, Rui, Yang, Yang, Werner, Henrica M.J., Eterovic, A. Karina, Yuan, Yuan, Li, Jun, Nair, Nikitha, Minelli, Rosalba, Tsang, Yiu Huen, Cheung, Lydia W.T., Jeong, Kang Jin, Roszik, Jason, Ju, Zhenlin, Woodman, Scott E., Lu, Yiling, Scott, Kenneth L., Li, Jin Billy, Mills, Gordon B., Liang, Han

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YAP/TAZ-Mediated Upregulation of GAB2 Leads to Increased Sensitivity to Growth Factor-Induced Activation of the PI3K Pathway von Wang, Chao, Gu, Chao, Jeong, Kang Jin, Zhang, Dong, Guo, Wei, Lu, Yiling, Ju, Zhenlin, Panupinthu, Nattapon, Yang, Ji Yeon, Gagea, Mihai Mike, Ng, Patrick Kwok Shing, Zhang, Fan, Mills, Gordon B

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DNA-Methyltransferase 1 Induces Dedifferentiation of Pancreatic Cancer Cells through Silencing of Krüppel-Like Factor 4 Expression von Xie, Victoria K, Li, Zhiwei, Yan, Yongmin, Jia, Zhiliang, Zuo, Xiangsheng, Ju, Zhenlin, Wang, Jing, Du, Jiawei, Xie, Dacheng, Xie, Keping, Wei, Daoyan

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Gene signature associated with resistance to fluvastatin chemoprevention for breast cancer von Bhardwaj, Anjana, Embury, Matthew D, Ju, Zhenlin, Wang, Jing, Bedrosian, Isabelle

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High frequency of PIK3R1 and PIK3R2 mutations in endometrial cancer elucidates a novel mechanism for regulation of PTEN protein stability von Cheung, Lydia W T, Hennessy, Bryan T, Li, Jie, Yu, Shuangxing, Myers, Andrea P, Djordjevic, Bojana, Lu, Yiling, Stemke-Hale, Katherine, Dyer, Mary D, Zhang, Fan, Ju, Zhenlin, Cantley, Lewis C, Scherer, Steven E, Liang, Han, Lu, Karen H, Broaddus, Russell R, Mills, Gordon B

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Essential roles of mitochondrial biogenesis regulator Nrf1 in retinal development and homeostasis von Kiyama, Takae, Chen, Ching-Kang, Wang, Steven W, Pan, Ping, Ju, Zhenlin, Wang, Jing, Takada, Shinako, Klein, William H, Mao, Chai-An

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The molecular heterogeneity of the precancerous breast affects drug efficacy von Bhardwaj, Anjana, Rojo, Raniv Dawey, Ju, Zhenlin, Koh, Alexander, Tachibana, Kazunoshin, Wang, Jing, Bedrosian, Isabelle

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Neomorphic PDGFRA extracellular domain driver mutations are resistant to PDGFRA targeted therapies von Ip, Carman K. M., Ng, Patrick K. S., Jeong, Kang Jin, Shao, S. H., Ju, Zhenlin, Leonard, P. G., Hua, Xu, Vellano, Christopher P., Woessner, Richard, Sahni, Nidhi, Scott, Kenneth L., Mills, Gordon B.

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Whole genome and reverse protein phase array landscapes of patient derived osteosarcoma xenograft models von Wu, Chia-Chin, Huang, Licai, Zhang, Zhongting, Ju, Zhenlin, Song, Xingzhi, Kolb, E. Anders, Zhang, Wendong, Gill, Jonathan, Ha, Min, Smith, Malcolm A., Houghton, Peter, Morton, Christopher L., Kurmasheva, Raushan, Maris, John, Mosse, Yael, Lu, Yiling, Gorlick, Richard, Futreal, P. Andrew, Beird, Hannah C.

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Integrated Molecular and Clinical Analysis of AKT Activation in Metastatic Melanoma von DAVIES, Michael A, STEMKE-HALE, Katherine, PRIETO, Victor G, ALDAPE, Kenneth, MILLS, Gordon B, GERSHENWALD, Jeffrey E, LIN, E, TELLEZ, Carmen, WANLENG DENG, GOPAL, Yennu N, WOODMAN, Scott E, CALDERONE, Tiffany C, ZHENLIN JU, LAZAR, Alexander J

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Naturally Occurring Neomorphic PIK3R1 Mutations Activate the MAPK Pathway, Dictating Therapeutic Response to MAPK Pathway Inhibitors von Cheung, Lydia W.T., Yu, Shuangxing, Zhang, Dong, Li, Jie, Ng, Patrick K.S., Panupinthu, Nattapon, Mitra, Shreya, Ju, Zhenlin, Yu, Qinghua, Liang, Han, Hawke, David H., Lu, Yiling, Broaddus, Russell R., Mills, Gordon B.

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Adaptation and Changes in Actin Dynamics and Cell Motility as Early Responses of Cultured Mammalian Cells to Altered Gravitational Vector von Ju, Zhenlin, Thomas, Tamlyn N, Chiu, Yi-Jen, Yamanouchi, Sakuya, Yoshida, Yukari, Abe, Jun-Ichi, Takahashi, Akihisa, Wang, Jing, Fujiwara, Keigi, Hada, Megumi

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Pla2g16 phospholipase mediates gain-of-function activities of mutant p53 von Xiong, Shunbin, Tu, Huolin, Kollareddy, Madhusudhan, Pant, Vinod, Li, Qin, Zhang, Yun, Jackson, James G., Suh, Young-Ah, Elizondo-Fraire, Ana C., Yang, Peirong, Chau, Gilda, Tashakori, Mehrnoosh, Wasylishen, Amanda R., Ju, Zhenlin, Solomon, Hilla, Rotter, Varda, Liu, Bin, El-Naggar, Adel K., Donehower, Lawrence A., Martinez, Luis Alfonso, Lozano, Guillermina

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Frequent mutation of receptor protein tyrosine phosphatases provides a mechanism for STAT3 hyperactivation in head and neck cancer von Lui, Vivian Wai Yan, Peyser, Noah D., Ng, Patrick Kwok-Shing, Hritz, Jozef, Zenga, Yan, Lu, Yiling, Li, Hua, Wang, Lin, Gilbert, Breean R., General, Ignacio J., Bahar, Ivet, Ju, Zhenlin, Wang, Zhenghe, Pendleton, Kelsey P., Xiao, Xiao, Yu Dua, Vries, John K., Hammerman, Peter S., Garraway, Levi A., Mills, Gordon B., Johnson, Daniel E., Grandis, Jennifer R.

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