Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening von Joung, Julia, Konermann, Silvana, Gootenberg, Jonathan S, Abudayyeh, Omar O, Platt, Randall J, Brigham, Mark D, Sanjana, Neville E, Zhang, Feng

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High-resolution interrogation of functional elements in the noncoding genome von Sanjana, Neville E., Wright, Jason, Zheng, Kaijie, Shalem, Ophir, Fontanillas, Pierre, Joung, Julia, Cheng, Christine, Regev, Aviv, Zhang, Feng

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A cytosine deaminase for programmable single-base RNA editing von Abudayyeh, Omar O., Gootenberg, Jonathan S., Franklin, Brian, Koob, Jeremy, Kellner, Max J., Ladha, Alim, Joung, Julia, Kirchgatterer, Paul, Cox, David B. T., Zhang, Feng

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C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector von Abudayyeh, Omar O., Gootenberg, Jonathan S., Konermann, Silvana, Joung, Julia, Slaymaker, Ian M., Cox, David B. T., Shmakov, Sergey, Makarova, Kira S., Semenova, Ekaterina, Minakhin, Leonid, Severinov, Konstantin, Regev, Aviv, Lander, Eric S., Koonin, Eugene V., Zhang, Feng

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Novel allele-dependent role for APOE in controlling the rate of synapse pruning by astrocytes von Chung, Won-Suk, Verghese, Philip B., Chakraborty, Chandrani, Joung, Julia, Hyman, Bradley T., Ulrich, Jason D., Holtzman, David M., Barres, Ben A.

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CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity von Joung, Julia, Kirchgatterer, Paul C., Singh, Ankita, Cho, Jang H., Nety, Suchita P., Larson, Rebecca C., Macrae, Rhiannon K., Deasy, Rebecca, Tseng, Yuen-Yi, Maus, Marcela V., Zhang, Feng

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Rapid SARS-CoV-2 testing in primary material based on a novel multiplex RT-LAMP assay von Schermer, Bernhard, Fabretti, Francesca, Damagnez, Maximilian, Di Cristanziano, Veronica, Heger, Eva, Arjune, Sita, Tanner, Nathan A, Imhof, Thomas, Koch, Manuel, Ladha, Alim, Joung, Julia, Gootenberg, Jonathan S, Abudayyeh, Omar O, Burst, Volker, Zhang, Feng, Klein, Florian, Benzing, Thomas, Müller, Roman-Ulrich

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Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma von Nie, Man, Du, Likun, Ren, Weicheng, Joung, Julia, Ye, Xiaofei, Shi, Xi, Ciftci, Sibel, Liu, Dongbing, Wu, Kui, Zhang, Feng, Pan-Hammarström, Qiang

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Application of CRISPR genetic screens to investigate neurological diseases von So, Raphaella W L, Chung, Sai Wai, Lau, Heather H C, Watts, Jeremy J, Gaudette, Erin, Al-Azzawi, Zaid A M, Bishay, Jossana, Lin, Lilian Tsai-Wei, Joung, Julia, Wang, Xinzhu, Schmitt-Ulms, Gerold

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221 CRISPR screen identifies loss of IFNγR signaling and downstream adhesion as a resistance mechanism to CAR T-cell cytotoxicity in solid but not liquid tumors von Larson, Rebecca, Kann, Michael, Bailey, Stefanie, Haradhvala, Nicholas, Stewart, Kai, Bouffard, Amanda, Scarfo, Irene, Leick, Mark, Berger, Trisha, Jan, Max, Joung, Julia, Ouspenskaia, Tamara, Law, Travis, Regev, Aviv, Getz, Gad, Maus, Marcela

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Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6 von Gootenberg, Jonathan S, Abudayyeh, Omar O, Kellner, Max J, Joung, Julia, Collins, James J, Zhang, Feng

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CRISPR technologies for genome, epigenome and transcriptome editing von Villiger, Lukas, Joung, Julia, Koblan, Luke, Weissman, Jonathan, Abudayyeh, Omar O., Gootenberg, Jonathan S.

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RNA editing with CRISPR-Cas13 von Cox, David B. T., Gootenberg, Jonathan S., Abudayyeh, Omar O., Franklin, Brian, Kellner, Max J., Joung, Julia, Zhang, Feng

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Orthogonal gene knockout and activation with a catalytically active Cas9 nuclease von Dahlman, James E, Abudayyeh, Omar O, Joung, Julia, Gootenberg, Jonathan S, Zhang, Feng, Konermann, Silvana

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Nucleic acid detection with CRISPR-Cas13a/C2c2 von Gootenberg, Jonathan S., Abudayyeh, Omar O., Lee, Jeong Wook, Essletzbichler, Patrick, Dy, Aaron J., Joung, Julia, Verdine, Vanessa, Donghia, Nina, Daringer, Nichole M., Freije, Catherine A., Myhrvold, Cameron, Bhattacharyya, Roby P., Livny, Jonathan, Regev, Aviv, Koonin, Eugene V., Hung, Deborah T., Sabeti, Pardis C., Collins, James J., Zhang, Feng

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RNA targeting with CRISPR–Cas13 von Abudayyeh, Omar O., Gootenberg, Jonathan S., Essletzbichler, Patrick, Han, Shuo, Joung, Julia, Belanto, Joseph J., Verdine, Vanessa, Cox, David B. T., Kellner, Max J., Regev, Aviv, Lander, Eric S., Voytas, Daniel F., Ting, Alice Y., Zhang, Feng

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Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex von Konermann, Silvana, Brigham, Mark D., Trevino, Alexandro E., Joung, Julia, Abudayyeh, Omar O., Barcena, Clea, Hsu, Patrick D., Habib, Naomi, Gootenberg, Jonathan S., Nishimasu, Hiroshi, Nureki, Osamu, Zhang, Feng

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CAR T cell killing requires the IFNγR pathway in solid but not liquid tumours von Larson, Rebecca C., Kann, Michael C., Bailey, Stefanie R., Haradhvala, Nicholas J., Llopis, Paula Montero, Bouffard, Amanda A., Scarfó, Irene, Leick, Mark B., Grauwet, Korneel, Berger, Trisha R., Stewart, Kai, Anekal, Praju Vikas, Jan, Max, Joung, Julia, Schmidts, Andrea, Ouspenskaia, Tamara, Law, Travis, Regev, Aviv, Getz, Gad, Maus, Marcela V.

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Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems von Shmakov, Sergey, Abudayyeh, Omar O., Makarova, Kira S., Wolf, Yuri I., Gootenberg, Jonathan S., Semenova, Ekaterina, Minakhin, Leonid, Joung, Julia, Konermann, Silvana, Severinov, Konstantin, Zhang, Feng, Koonin, Eugene V.

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Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System von Zetsche, Bernd, Gootenberg, Jonathan S., Abudayyeh, Omar O., Slaymaker, Ian M., Makarova, Kira S., Essletzbichler, Patrick, Volz, Sara E., Joung, Julia, van der Oost, John, Regev, Aviv, Koonin, Eugene V., Zhang, Feng

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