A novel and efficient approach to high-throughput production of HLA-E/peptide monomer for T-cell epitope screening von Vaurs, Juliette, Douchin, Gaël, Echasserieau, Klara, Oger, Romain, Jouand, Nicolas, Fortun, Agnès, Hesnard, Leslie, Croyal, Mikaël, Pecorari, Frédéric, Gervois, Nadine, Bernardeau, Karine

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The inhibitory receptor CD94/NKG2A on CD8+ tumor-infiltrating lymphocytes in colorectal cancer: a promising new druggable immune checkpoint in the context of HLAE/β2m overexpressio... von Eugène, Juliette, Jouand, Nicolas, Ducoin, Kathleen, Dansette, Delphine, Oger, Romain, Deleine, Cécile, Leveque, Edouard, Meurette, Guillaume, Podevin, Juliette, Matysiak, Tamara, Bennouna, Jaafar, Bezieau, Stéphane, Volteau, Christelle, Thomas, Wassila El Alami, Chetritt, Jerôme, Kerdraon, Olivier, Fourquier, Pierre, Thibaudeau, Emilie, Dumont, Frédéric, Mosnier, Jean-François, Toquet, Claire, Jarry, Anne, Gervois, Nadine, Bossard, Céline

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Targeting NKG2A to boost anti-tumor CD8 T-cell responses in human colorectal cancer von Ducoin, Kathleen, Oger, Romain, Bilonda Mutala, Linda, Deleine, Cécile, Jouand, Nicolas, Desfrançois, Juliette, Podevin, Juliette, Duchalais, Emilie, Cruard, Jonathan, Benlalam, Houssem, Labarrière, Nathalie, Bossard, Céline, Jarry, Anne, Gervois-Segain, Nadine

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HCMV triggers frequent and persistent UL40-specific unconventional HLA-E-restricted CD8 T-cell responses with potential autologous and allogeneic peptide recognition von Jouand, Nicolas, Bressollette-Bodin, Céline, Gérard, Nathalie, Giral, Magali, Guérif, Pierrick, Rodallec, Audrey, Oger, Romain, Parrot, Tiphaine, Allard, Mathilde, Cesbron-Gautier, Anne, Gervois, Nadine, Charreau, Béatrice

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Phase I/II clinical trial of adoptive cell transfer of sorted specific T cells for metastatic melanoma patients von Dréno, Brigitte, Khammari, Amir, Fortun, Agnès, Vignard, Virginie, Saiagh, Soraya, Beauvais, Tiffany, Jouand, Nicolas, Bercegay, Sylvain, Simon, Sylvain, Lang, François, Labarrière, Nathalie

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Human gut microbiota-reactive DP8α regulatory T cells, signature and related emerging functions von Jotereau, Francine, Alameddine, Joudy, Teusan, Raluca, Pédron, Annabelle, Jouand, Nicolas, Altare, Frédéric, Godefroy, Emmanuelle

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Interplay between oncolytic measles virus, macrophages and cancer cells induces a proinflammatory tumor microenvironment von Chatelain, Camille, Berland, Laurine, Grard, Marion, Jouand, Nicolas, Fresquet, Judith, Nader, Joëlle, Hirigoyen, Ugo, Petithomme, Tacien, Combredet, Chantal, Pons-Tostivint, Elvire, Fradin, Delphine, Treps, Lucas, Blanquart, Christophe, Boisgerault, Nicolas, Tangy, Frédéric, Fonteneau, Jean-François

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PD-1 and TIGIT coexpression identifies a circulating CD8 T cell subset predictive of response to anti-PD-1 therapy von Simon, Sylvain, Voillet, Valentin, Vignard, Virginie, Wu, Zhong, Dabrowski, Camille, Jouand, Nicolas, Beauvais, Tiffany, Khammari, Amir, Braudeau, Cécile, Josien, Régis, Adotevi, Olivier, Laheurte, Caroline, Aubin, François, Nardin, Charles, Rulli, Samuel, Gottardo, Raphael, Ramchurren, Nirasha, Cheever, Martin, Fling, Steven P, Church, Candice D, Nghiem, Paul, Dreno, Brigitte, Riddell, Stanley R, Labarriere, Nathalie

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Low Levels of Natural Anti-α- N -Acetylgalactosamine (Tn) Antibodies Are Associated With COVID-19 von Breiman, Adrien, Ruvoën-Clouet, Nathalie, Deleers, Marie, Beauvais, Tiffany, Jouand, Nicolas, Rocher, Jézabel, Bovin, Nicolai, Labarrière, Nathalie, El Kenz, Hanane, Le Pendu, Jacques

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High-Density of FcγRIIIA+ (CD16+) Tumor-Associated Neutrophils in Metastases Improves the Therapeutic Response of Cetuximab in Metastatic Colorectal Cancer Patients, Independently... von Denis Musquer, Marie, Jouand, Nicolas, Pere, Morgane, Lamer, Juliette Eugène, Bézieau, Stéphane, Matysiak, Tamara, Faroux, Roger, Caroli Bosc, François-Xavier, Rousselet, Marie-Christine, Leclair, François, Mosnier, Jean-François, Toquet, Claire, Gervois, Nadine, Bossard, Céline

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MicroRNAs in Tumor Exosomes Drive Immune Escape in Melanoma von Vignard, Virginie, Labbé, Maureen, Marec, Nadège, André-Grégoire, Gwennan, Jouand, Nicolas, Fonteneau, Jean-François, Labarrière, Nathalie, Fradin, Delphine

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Defining the Immune Checkpoint Landscape in Human Colorectal Cancer Highlights the Relevance of the TIGIT/CD155 Axis for Optimizing Immunotherapy von Ducoin, Kathleen, Bilonda-Mutala, Linda, Deleine, Cécile, Oger, Romain, Duchalais, Emilie, Jouand, Nicolas, Bossard, Céline, Jarry, Anne, Gervois-Segain, Nadine

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Abstract 4061: The inflammasome of tumor cells modulates the biology of tumor-infiltrating T lymphocytes in colorectal cancer von Bilonda, Linda, Dansette, Delphine, Deleine, Cecile, Oger, Romain, Jouand, Nicolas, Podevin, Juliette, Fourquier, Pierre, Thibaudeau, Emilie, Chetritt, Jerome, Mosnier, Jean-François, Bossard, Celine, Gervois, Nadine, Jarry, Anne

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Low levels of natural anti-a-N-acetylgalactosamine (Tn) antibodies are associated with COVID-19 von Breiman, Adrien, Ruvoën-Clouet, Nathalie, Deleers, Marie, Beauvais, Tiffany, Jouand, Nicolas, Rocher, Jézabel, Bovin, Nicolai, Labarrière, Nathalie, El Kenz, Hanane, Le Pendu, Jacques

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Abstract 4476: PD-1 and TIGIT co-expression identifies a circulating CD8 T cell population predictive of response to anti-PD-1 therapy in melanoma and Merkel-cell carcinoma patient... von Simon, Sylvain, Voillet, Valentin, Vignard, Virginie, Wu, Zhong, Dabrowski, Camille, Jouand, Nicolas, Beauvais, Tiffany, Khammari, Amir, Braudeau, Cecile, Josien, Regis, Adotevi, Olivier, Laheurte, Caroline, Aubin, Francçois, Nardin, Charles, Rulli, Samuel, Gottardo, Raphaël, Ramchurren, Nirasha, Martin, Cheever, Fling, Steven P., Church, Candice D., Nghiem, Paul, Dreno, Brigitte, Riddell, Stanley R., Labarriere, Nathalie

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Role of the inflammasome of tumor cells in modulating the biology of Tumor Infiltrating T lymphocytes (TILs) in colorectal cancer von Jarry, Anne, Ouairy, Adrien, Dansette, Delphine, Deleine, Cécile, Jouand, Nicolas, Oger, Romain, Podevin, Juliette, Fourquier, Pierre, Thibaudeau, Emilie, Chetritt, Jerome, Mosnier, Jean-François, Gervois, Nadine, Bossard, Celine

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Role of the inflammasome of tumor cells in modulating the biology of Tumor Infiltrating T lymphocytes (TILs) in colorectal cancer von Bossard, Celine, Dansette, Delphine, Ouairy, Adrien, Jouand, Nicolas, Oger, Romain, Bou-Hanna, Chantal, Laboisse, Christian, Mosnier, Jean-François, Gervois, Nadine, Jarry, Anne

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Intraepithelial CD94+ tumor-infiltrating lymphocytes in a context of HLA-E overexpression as a new immune checkpoint to predict prognosis in colorectal carcinomas von Bossard, Celine, Eugene, Juliette, Jouand, Nicolas, Dansette, Delphine, Leveque, Edouard, Podevin, Juliette, Matysiak, Tamara, Bezieau, Stephane, Chetritt, Jerome, Kerdraon, Olivier, Fourquier, Pierre, Thibaudeau, Emilie, Mosnier, Jean-François, Jarry, Anne, Gervois, Nadine

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Abstract LB-142: CD94/NKG2A+ tumor-infiltrating lymphocytes in a context of HLA-E overexpression could be a promising new druggable inhibitory immune checkpoint in colorectal adeno... von EUGENE, Juliette, JOUAND, Nicolas, DANSETTE, Delphine, MEURETTE, Guillaume, Podevin, Juliette, MATYSIAK, Tamara, BEZIEAU, Stephane, VOLTEAU, Christelle, THOMAS, Wassila EL ALAMI, CHETRITT, Jerome, KERDRAON, Olivier, Fourquier, Pierre, THIBAUDEAU, Emilie, DUMONT, Frederic, MOSNIER, Jean-Francois, TOQUET, Claire, JARRY, Anne, GERVOIS, Nadine, Bossard, Celine

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CD40L confers helper functions to human intra-melanoma class-I-restricted CD4+CD8+ double positive T cells von Parrot, Tiphaine, Oger, Romain, Benlalam, Houssem, Raingeard de la Blétière, Diane, Jouand, Nicolas, Coutolleau, Anne, Preisser, Laurence, Khammari, Amir, Dréno, Brigitte, Guardiola, Philippe, Delneste, Yves, Labarrière, Nathalie, Gervois, Nadine

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