ANTI-FLT-1 ANTIBODIES IN TREATING DUCHENNE MUSCULAR DYSTROPHY FLT-1 von LUBY, Thomas M. TM, JOSIAH, Serene S, CHARNAS, Lawrence L, KEEFE, Dennis D, ASAKURA, Atsushi A

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Inhibition of FLT1 ameliorates muscular dystrophy phenotype by increased vasculature in a mouse model of Duchenne muscular dystrophy von Verma, Mayank, Shimizu-Motohashi, Yuko, Asakura, Yoko, Ennen, James P, Bosco, Jennifer, Zhou, Zhiwei, Fong, Guo-Hua, Josiah, Serene, Keefe, Dennis, Asakura, Atsushi

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Randomized, Double-Masked, Placebo-Controlled Dose Escalation Study of TAK-639 Topical Ophthalmic Solution in Subjects with Ocular Hypertension or Primary Open-Angle Glaucoma von Martin, Patrick, Cohen, Alisa, Uddin, Sharif, Epelbaum, Laura, Josiah, Serene

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Effects of TAK-639, a novel topical C-type natriuretic peptide analog, on intraocular pressure and aqueous humor dynamics in mice von Millar, J. Cameron, Savinainen, Anneli, Josiah, Serene, Pang, Iok-Hou

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Interpretation of Uniform-Well Readouts von Josiah, Serene

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Pharmacokinetics and intraocular pressure–lowering activity of TAK-639, a novel C-type natriuretic peptide analog, in rabbit, dog, and monkey von Savinainen, Anneli, Prusakiewicz, Jeffery J., Oswald, Justine, Spencer, Elizabeth, Lou, Zhen, Cohen, Marita Larsson, Rashidzadeh, Hassan, Josiah, Serene

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Hypothermia associated with a putative ophthalmic therapeutic in preclinical species von Derakhchan, Kathy, Savinainen, Anneli, Newman, Jennifer, Josiah, Serene, Carey, Galen

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Individualized Prediction of Changes in 6-Minute Walk Distance for Patients with Duchenne Muscular Dystrophy von Goemans, Nathalie, Vanden Hauwe, Marleen, Signorovitch, James, Swallow, Elyse, Song, Jinlin

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VEGFR-1/Flt-1 inhibition increases angiogenesis and improves muscle function in a mouse model of Duchenne muscular dystrophy von Bosco, Jennifer, Zhou, Zhiwei, Gabriëls, Sofie, Verma, Mayank, Liu, Nan, Miller, Brian K., Gu, Sheng, Lundberg, Dianna M., Huang, Yan, Brown, Eilish, Josiah, Serene, Meiyappan, Muthuraman, Traylor, Matthew J., Chen, Nancy, Asakura, Atsushi, De Jonge, Natalie, Blanchetot, Christophe, de Haard, Hans, Duffy, Heather S., Keefe, Dennis

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Evaluation of SRD005825 as a substrate and inhibitor of a panel of human drug transporters von Luo, Gang, Welty, Devin, Josiah, Serene, Gast, Manuela, Lee, Deborah, Keehn, Ryan, Albaugh, Daniel, McKenzie, Donald, Lou, Zhen

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Identification of human cyp enzymes involved in the metabolism of 14 C-SRD005825 von Luo, Gang, Welty, Devin, Leitz, Sara, Wanta, Jody, Albaugh, Daniel, Josiah, Serene, McKenzie, Donald, Lou, Zhen

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Evaluation of inhibitory potential of SRD005825 on human CYP enzymes von Lou, Zhen, Leitz, Sara, Welty, Devin, Wanta, Jody, Albaugh, Daniel, Nehmer, Amy, Josiah, Serene, McKenzie, Donald, Luo, Gang

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Metabolism of 14 C-SRD005825 in mouse, rat, dog, monkey, and human hepatic microsomes von Lou, Zhen, Braga, Thiago, Welty, Devin, Josiah, Serene, Wanta, Jody, Leitz, Sara, Gohdes, Mark, Albaugh, Daniel, Nehmer, Amy, McKenzie, Donald, Luo, Gang

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Identification of human cyp enzymes involved in the metabolism of 14C-SRD005825 von Luo, Gang, Welty, Devin, Leitz, Sara, Wanta, Jody, Albaugh, Daniel, Josiah, Serene, McKenzie, Donald, Lou, Zhen

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Direct cloning of double-stranded RNAs from RNase protection analysis reveals processing patterns of C/D box snoRNAs and provides evidence for widespread antisense transcript expre... von Shen, Manli, Eyras, Eduardo, Wu, Jie, Khanna, Amit, Josiah, Serene, Rederstorff, Mathieu, Zhang, Michael Q., Stamm, Stefan

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Metabolism of 14C-SRD005825 in mouse, rat, dog, monkey, and human hepatic microsomes von Lou, Zhen, Braga, Thiago, Welty, Devin, Josiah, Serene, Wanta, Jody, Leitz, Sara, Gohdes, Mark, Albaugh, Daniel, Nehmer, Amy, McKenzie, Donald, Luo, Gang

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SRD005825 Acts as a Pharmacologic Chaperone of Opsin and Promotes Survival of Photoreceptors in an Animal Model of Autosomal Dominant Retinitis Pigmentosa von Ahmed, Chulbul M, Dwyer, Brian T, Romashko, All, Van Adestine, Stev, Park, Eun-He, Lou, Zhe, Welty, Devi, Josiah, Seren, Savinainen, Annel, Zhang, Bohon, Lewin, Alfred S

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Intracellular TGF-β Receptor Blockade Abrogates Smad-Dependent Fibroblast Activation In Vitro and In Vivo von Ishida, Wataru, Mori, Yasuji, Lakos, Gabriella, Sun, Lihong, Shan, Feng, Bowes, Scott, Josiah, Serene, Lee, Wen-Cherng, Singh, Juswinder, Ling, Leona E., Varga, John

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Successful shape-based virtual screening: The discovery of a potent inhibitor of the type I TGFβ receptor kinase (TβRI) von JUSWINDER SINGH, CHUAQUI, Claudio E, PAPADATOS, James L, BOWES, Scott, JOSIAH, Serene, LING, Leona E, BORIACK-SJODIN, P. Ann, LEE, Wen-Cherng, PONTZ, Timothy, CORBLEY, Michael J, CHEUNG, H.-Kam, ARDUINI, Robert M, MEAD, Jonathan N, NEWMAN, Miki N

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Direct cloning of double-stranded RNAs from RNase protection analysis reveals processing patterns of C/D box snoRNAs and provides evidence for widespread antisense transcript expre... von Shen, Manli, Eyras Jiménez, Eduardo, Wu, Jie, Josiah, Serene, Rederstorff, Mathieu, Zhang, Michael Q, Stamm, Stefan

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