Safety, efficacy, and dose response of the maturation inhibitor GSK3532795 (formerly known as BMS-955176) plus tenofovir/emtricitabine once daily in treatment-naive HIV-1-infected... von Morales-Ramirez, Javier, Bogner, Johannes R, Molina, Jean-Michel, Lombaard, Johan, Dicker, Ira B, Stock, David A, DeGrosky, Michelle, Gartland, Margaret, Pene Dumitrescu, Teodora, Min, Sherene, Llamoso, Cyril, Joshi, Samit R, Lataillade, Max

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Viral Drug Resistance through 48 Weeks, in a Phase 2b, Randomized, Controlled Trial of the HIV-1 Attachment Inhibitor Prodrug, Fostemsavir von Lataillade, Max, Zhou, Nannan, Joshi, Samit R, Lee, Sangil, Stock, David A, Hanna, George J, Krystal, Mark

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Dysregulation of human Toll-like receptor function in aging von Shaw, Albert C, Panda, Alexander, Joshi, Samit R, Qian, Feng, Allore, Heather G, Montgomery, Ruth R

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A Phase I Evaluation of the Pharmacokinetics and Tolerability of the HIV-1 Maturation Inhibitor GSK3640254 and Tenofovir Alafenamide/Emtricitabine in Healthy Participants von Dumitrescu, Teodora Pene, Joshi, Samit R., Xu, Jianfeng, Zhan, Joyce, Johnson, Mark, Butcher, Laurie, Zimmerman, Eric, Webster, Lindsey, Davidson, Antonia M., Lataillade, Max, Min, Sherene

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Phase IIa Proof-of-Concept Evaluation of the Antiviral Efficacy, Safety, Tolerability, and Pharmacokinetics of the Next-Generation Maturation Inhibitor GSK3640254 von Spinner, Christoph D, Felizarta, Franco, Rizzardini, Giuliano, Philibert, Patrick, Mitha, Essack, Domingo, Pere, Stephan, Christoph J, DeGrosky, Michelle, Bainbridge, Veronica, Zhan, Joyce, Dumitrescu, Teodora Pene, Jeffrey, Jerry L, Xu, Jianfeng, Halliday, Fiona, Gan, Jianjun, Johnson, Mark, Gartland, Martin, Joshi, Samit R, Lataillade, Max

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Phase I evaluation of pharmacokinetics and tolerability of the HIV‐1 maturation inhibitor GSK3640254 and dolutegravir in healthy adults von Pene Dumitrescu, Teodora, Joshi, Samit R., Xu, Jianfeng, Greene, Thomas J., Johnson, Mark, Butcher, Laurie, Zimmerman, Eric, Webster, Lindsey, Pham, Theresa T., Lataillade, Max, Min, Sherene

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Lack of pharmacokinetic interaction between the HIV‐1 maturation inhibitor GSK3640254 and combination oral contraceptives in healthy women von Pene Dumitrescu, Teodora, Greene, Thomas J., Joshi, Samit R., Xu, Jianfeng, Johnson, Mark, Halliday, Fiona, Butcher, Laurie, Zimmerman, Eric, Webster, Lindsey, Pham, Theresa T., Lataillade, Max, Min, Sherene

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Top3β is an RNA topoisomerase that works with fragile X syndrome protein to promote synapse formation von Xu, Dongyi, Shen, Weiping, Guo, Rong, Xue, Yutong, Peng, Wei, Sima, Jian, Yang, Jay, Sharov, Alexei, Srikantan, Subramanya, Yang, Jiandong, Fox, David, Qian, Yong, Martindale, Jennifer L, Piao, Yulan, Machamer, James, Joshi, Samit R, Mohanty, Subhasis, Shaw, Albert C, Lloyd, Thomas E, Brown, Grant W, Ko, Minoru S H, Gorospe, Myriam, Zou, Sige, Wang, Weidong

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Resistance profile of the HIV-1 maturation inhibitor GSK3532795 in vitro and in a clinical study von Dicker, Ira, Zhang, Sharon, Ray, Neelanjana, Beno, Brett R, Regueiro-Ren, Alicia, Joshi, Samit, Cockett, Mark, Krystal, Mark, Lataillade, Max

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Metabolomic and transcriptomic signatures of influenza vaccine response in healthy young and older adults von Chou, Chih‐Hung, Mohanty, Subhasis, Kang, Heather A., Kong, Lingjia, Avila‐Pacheco, Julian, Joshi, Samit R., Ueda, Ikuyo, Devine, Lesley, Raddassi, Khadir, Pierce, Kerry, Jeanfavre, Sarah, Bullock, Kevin, Meng, Hailong, Clish, Clary, Santori, Fabio R., Shaw, Albert C., Xavier, Ramnik J.

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Prolonged Proinflammatory Cytokine Production in Monocytes Modulated by Interleukin 10 After Influenza Vaccination in Older Adults von Mohanty, Subhasis, Joshi, Samit R., Ueda, Ikuyo, Wilson, Jean, Blevins, Tamara P., Siconolfi, Barbara, Meng, Hailong, Devine, Lesley, Raddassi, Khadir, Tsang, Sui, Belshe, Robert B., Hafler, David A., Kaech, Susan M., Kleinstein, Steven H., Trentalange, Mark, Allore, Heather G., Shaw, Albert C.

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Multiple network-constrained regressions expand insights into influenza vaccination responses von Avey, Stefan, Mohanty, Subhasis, Wilson, Jean, Zapata, Heidi, Joshi, Samit R, Siconolfi, Barbara, Tsang, Sui, Shaw, Albert C, Kleinstein, Steven H

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Phase I evaluation of the safety, tolerability, and pharmacokinetics of GSK3640254, a next‐generation HIV‐1 maturation inhibitor von Joshi, Samit R., Fernando, Disala, Igwe, Stephanie, McKenzie, Litza, Krishnatry, Anu S., Halliday, Fiona, Zhan, Joyce, Greene, Thomas J., Xu, Jianfeng, Ferron‐Brady, Geraldine, Lataillade, Max, Min, Sherene

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Relative Bioavailability and Food Effect of GSK3640254 Tablet and Capsule Formulations in Healthy Participants von Johnson, Mark, Pene Dumitrescu, Teodora, Joshi, Samit R., Mathew, Ashwin, Bainbridge, Veronica, Zhan, Joyce, Lataillade, Max

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Exploring HIV-1 Maturation: A New Frontier in Antiviral Development von McGraw, Aidan, Hillmer, Grace, Medehincu, Stefania M, Hikichi, Yuta, Gagliardi, Sophia, Narayan, Kedhar, Tibebe, Hasset, Marquez, Dacia, Mei Bose, Lilia, Keating, Adleigh, Izumi, Coco, Peese, Kevin, Joshi, Samit, Krystal, Mark, DeCicco-Skinner, Kathleen L, Freed, Eric O, Sardo, Luca, Izumi, Taisuke

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Effects of the HIV‐1 maturation inhibitor GSK3640254 on QT interval in healthy participants von Zhang, Ying, Bush, Mark, Yazdani, Parto, Zhan, Joyce, Wen, Bo, Bainbridge, Veronica, Wynne, Brian R., Joshi, Samit, Lataillade, Max

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Safety and efficacy of the HIV-1 attachment inhibitor prodrug BMS-663068 in treatment-experienced individuals: 24 week results of AI438011, a phase 2b, randomised controlled trial von Lalezari, Jacob P, Dr, Latiff, Gulam H, MD, Brinson, Cynthia, MD, Echevarría, Juan, MD, Treviño-Pérez, Sandra, MD, Bogner, Johannes R, Prof, Thompson, Melanie, MD, Fourie, Jan, MD, Sussmann Pena, Otto A, MD, Mendo Urbina, Fernando C, MD, Martins, Marcelo, MD, Diaconescu, Iulian G, MD, Stock, David A, PhD, Joshi, Samit R, DO, Hanna, George J, MD, Lataillade, Max, DO

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Aging-dependent alterations in gene expression and a mitochondrial signature of responsiveness to human influenza vaccination von Thakar, Juilee, Mohanty, Subhasis, West, A Phillip, Joshi, Samit R, Ueda, Ikuyo, Wilson, Jean, Meng, Hailong, Blevins, Tamara P, Tsang, Sui, Trentalange, Mark, Siconolfi, Barbara, Park, Koonam, Gill, Thomas M, Belshe, Robert B, Kaech, Susan M, Shadel, Gerald S, Kleinstein, Steven H, Shaw, Albert C

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Safety and efficacy of the HIV-1 attachment inhibitor prodrug fostemsavir in antiretroviral-experienced subjects: week 48 analysis of AI438011, a Phase IIb, randomized controlled t... von Thompson, Melanie, Lalezari, Jacob P, Kaplan, Richard, Pinedo, Yvett, Pena, Otto A Sussmann, Cahn, Pedro, Stock, David A, Joshi, Samit R, Hanna, George J, Lataillade, Max

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Multicolor Digital Flow Cytometry in Human Translational Immunology von Joshi, Samit R., Mohanty, Subhasis, Shaw, Albert C.

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