Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity von Meng, Bo, Abdullahi, Adam, Ferreira, Isabella A. T. M., Goonawardane, Niluka, Saito, Akatsuki, Kimura, Izumi, Yamasoba, Daichi, Gerber, Pehuén Pereyra, Fatihi, Saman, Rathore, Surabhi, Zepeda, Samantha K., Papa, Guido, Kemp, Steven A., Ikeda, Terumasa, Toyoda, Mako, Tan, Toong Seng, Kuramochi, Jin, Mitsunaga, Shigeki, Ueno, Takamasa, Shirakawa, Kotaro, Takaori-Kondo, Akifumi, Brevini, Teresa, Mallery, Donna L., Charles, Oscar J., Bowen, John E., Joshi, Anshu, Walls, Alexandra C., Jackson, Laurelle, Martin, Darren, Smith, Kenneth G. C., Bradley, John, Briggs, John A. G., Choi, Jinwook, Madissoon, Elo, Meyer, Kerstin B., Mlcochova, Petra, Ceron-Gutierrez, Lourdes, Doffinger, Rainer, Teichmann, Sarah A., Fisher, Andrew J., Pizzuto, Matteo S., de Marco, Anna, Corti, Davide, Hosmillo, Myra, Lee, Joo Hyeon, James, Leo C., Thukral, Lipi, Veesler, David, Sigal, Alex, Sampaziotis, Fotios, Goodfellow, Ian G., Matheson, Nicholas J., Sato, Kei, Gupta, Ravindra K.

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SARS-CoV-2 evolution during treatment of chronic infection von Kemp, Steven A., Collier, Dami A., Datir, Rawlings P., Ferreira, Isabella A. T. M., Gayed, Salma, Jahun, Aminu, Hosmillo, Myra, Rees-Spear, Chloe, Mlcochova, Petra, Lumb, Ines Ushiro, Roberts, David J., Chandra, Anita, Temperton, Nigel, Sharrocks, Katherine, Blane, Elizabeth, Modis, Yorgo, Leigh, Kendra E., Briggs, John A. G., van Gils, Marit J., Smith, Kenneth G. C., Bradley, John R., Smith, Chris, Doffinger, Rainer, Ceron-Gutierrez, Lourdes, Barcenas-Morales, Gabriela, Pollock, David D., Goldstein, Richard A., Smielewska, Anna, Skittrall, Jordan P., Gouliouris, Theodore, Goodfellow, Ian G., Gkrania-Klotsas, Effrossyni, Illingworth, Christopher J. R., McCoy, Laura E., Gupta, Ravindra K.

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Age-related immune response heterogeneity to SARS-CoV-2 vaccine BNT162b2 von Collier, Dami A., Ferreira, Isabella A. T. M., Kotagiri, Prasanti, Datir, Rawlings P., Lim, Eleanor Y., Touizer, Emma, Meng, Bo, Abdullahi, Adam, Elmer, Anne, Kingston, Nathalie, Graves, Barbara, Le Gresley, Emma, Caputo, Daniela, Bergamaschi, Laura, Smith, Kenneth G. C., Bradley, John R., Ceron-Gutierrez, Lourdes, Cortes-Acevedo, Paulina, Barcenas-Morales, Gabriela, Linterman, Michelle A., McCoy, Laura E., Davis, Chris, Thomson, Emma, Lyons, Paul A., McKinney, Eoin, Doffinger, Rainer, Wills, Mark, Gupta, Ravindra K.

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Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies von Collier, Dami A., De Marco, Anna, Ferreira, Isabella A. T. M., Meng, Bo, Datir, Rawlings P., Walls, Alexandra C., Kemp, Steven A., Bassi, Jessica, Pinto, Dora, Silacci-Fregni, Chiara, Bianchi, Siro, Tortorici, M. Alejandra, Bowen, John, Culap, Katja, Jaconi, Stefano, Cameroni, Elisabetta, Snell, Gyorgy, Pizzuto, Matteo S., Pellanda, Alessandra Franzetti, Garzoni, Christian, Riva, Agostino, Elmer, Anne, Kingston, Nathalie, Graves, Barbara, McCoy, Laura E., Smith, Kenneth G. C., Bradley, John R., Temperton, Nigel, Ceron-Gutierrez, Lourdes, Barcenas-Morales, Gabriela, Harvey, William, Virgin, Herbert W., Lanzavecchia, Antonio, Piccoli, Luca, Doffinger, Rainer, Wills, Mark, Veesler, David, Corti, Davide, Gupta, Ravindra K.

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Single-cell multi-omics analysis of the immune response in COVID-19 von Stephenson, Emily, Reynolds, Gary, Botting, Rachel A., Calero-Nieto, Fernando J., Morgan, Michael D., Tuong, Zewen Kelvin, Bach, Karsten, Sungnak, Waradon, Worlock, Kaylee B., Yoshida, Masahiro, Kumasaka, Natsuhiko, Kania, Katarzyna, Engelbert, Justin, Olabi, Bayanne, Spegarova, Jarmila Stremenova, Wilson, Nicola K., Mende, Nicole, Jardine, Laura, Gardner, Louis C. S., Goh, Issac, Horsfall, Dave, McGrath, Jim, Webb, Simone, Mather, Michael W., Lindeboom, Rik G. H., Dann, Emma, Huang, Ni, Polanski, Krzysztof, Prigmore, Elena, Gothe, Florian, Scott, Jonathan, Payne, Rebecca P., Baker, Kenneth F., Hanrath, Aidan T., Schim van der Loeff, Ina C. D., Barr, Andrew S., Sanchez-Gonzalez, Amada, Bergamaschi, Laura, Mescia, Federica, Barnes, Josephine L., Kilich, Eliz, de Wilton, Angus, Saigal, Anita, Saleh, Aarash, Janes, Sam M., Smith, Claire M., Gopee, Nusayhah, Wilson, Caroline, Coupland, Paul, Coxhead, Jonathan M., Kiselev, Vladimir Yu, van Dongen, Stijn, Bacardit, Jaume, King, Hamish W., Rostron, Anthony J., Simpson, A. John, Hambleton, Sophie, Laurenti, Elisa, Lyons, Paul A., Meyer, Kerstin B., Nikolić, Marko Z., Duncan, Christopher J. A., Smith, Kenneth G. C., Teichmann, Sarah A., Clatworthy, Menna R., Marioni, John C., Göttgens, Berthold, Haniffa, Muzlifah

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Longitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease von Bergamaschi, Laura, Mescia, Federica, Turner, Lorinda, Hanson, Aimee L., Kotagiri, Prasanti, Dunmore, Benjamin J., Ruffieux, Hélène, De Sa, Aloka, Huhn, Oisín, Morgan, Michael D., Gerber, Pehuén Pereyra, Wills, Mark R., Baker, Stephen, Calero-Nieto, Fernando J., Doffinger, Rainer, Dougan, Gordon, Elmer, Anne, Goodfellow, Ian G., Gupta, Ravindra K., Hosmillo, Myra, Hunter, Kelvin, Kingston, Nathalie, Lehner, Paul J., Matheson, Nicholas J., Nicholson, Jeremy K., Petrunkina, Anna M., Richardson, Sylvia, Saunders, Caroline, Thaventhiran, James E.D., Toonen, Erik J.M., Weekes, Michael P., Göttgens, Berthold, Toshner, Mark, Hess, Christoph, Bradley, John R., Lyons, Paul A., Smith, Kenneth G.C.

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A thermostable, closed SARS-CoV-2 spike protein trimer von Xiong, Xiaoli, Qu, Kun, Ciazynska, Katarzyna A., Hosmillo, Myra, Carter, Andrew P., Ebrahimi, Soraya, Ke, Zunlong, Scheres, Sjors H. W., Bergamaschi, Laura, Grice, Guinevere L., Zhang, Ying, Nathan, James A., Baker, Stephen, James, Leo C., Baxendale, Helen E., Goodfellow, Ian, Doffinger, Rainer, Briggs, John A. G.

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Rapid diagnostic testing method to detect ROB β-lactamase gene in Neisseria meningitidis von Peifer, Andrew, Kidney, Anna, Nattanmai, Geetha, Wahl, Kate, Jose, Sherly, Owuor, Elizabeth, Randall, Linnell, Klingbeil, Erin, Musser, Kimberlee A, Mitchell, Kara

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Streptococcus sciuri sp. nov., Staphylococcus marylandisciuri sp. nov. and Staphylococcus americanisciuri sp. nov., isolated from faeces of eastern grey squirrel ( Sciurus caroline... von Volokhov, Dmitriy V, Zagorodnyaya, Tatiana A, Furtak, Vyacheslav A, Nattanmai, Geetha, Randall, Linnell, Jose, Sherly, Gao, Yamei, Eisenberg, Tobias, Delmonte, Pierluigi, Blom, Jochen, Mitchell, Kara K

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Age-associated B cells predict impaired humoral immunity after COVID-19 vaccination in patients receiving immune checkpoint blockade von Yam-Puc, Juan Carlos, Hosseini, Zhaleh, Horner, Emily C., Gerber, Pehuén Pereyra, Beristain-Covarrubias, Nonantzin, Hughes, Robert, Lulla, Aleksei, Rust, Maria, Boston, Rebecca, Ali, Magda, Fischer, Katrin, Simmons-Rosello, Edward, O’Reilly, Martin, Robson, Harry, Booth, Lucy H., Kahanawita, Lakmini, Correa-Noguera, Andrea, Favara, David, Ceron-Gutierrez, Lourdes, Keller, Baerbel, Craxton, Andrew, Anderson, Georgina S. F., Sun, Xiao-Ming, Elmer, Anne, Saunders, Caroline, Bermperi, Areti, Jose, Sherly, Kingston, Nathalie, Mulroney, Thomas E., Piñon, Lucia P. G., Chapman, Michael A., Grigoriadou, Sofia, MacFarlane, Marion, Willis, Anne E., Patil, Kiran R., Spencer, Sarah, Staples, Emily, Warnatz, Klaus, Buckland, Matthew S., Hollfelder, Florian, Hyvönen, Marko, Döffinger, Rainer, Parkinson, Christine, Lear, Sara, Matheson, Nicholas J., Thaventhiran, James E. D.

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SARS-CoV-2 spike N-terminal domain modulates TMPRSS2-dependent viral entry and fusogenicity von Meng, Bo, Choi, Jinwook, Baker, Stephen, Dougan, Gordon, Hess, Christoph, Kingston, Nathalie, Lehner, Paul J., Lyons, Paul A., Matheson, Nicholas J., Owehand, Willem H., Saunders, Caroline, Summers, Charlotte, Thaventhiran, James E.D., Toshner, Mark, Weekes, Michael P., Maxwell, Patrick, Shaw, Ashley, Calder, Jo, Canna, Laura, Domingo, Jason, Fuller, Stewart, Harris, Julie, Hewitt, Sarah, Kennet, Jane, Jose, Sherly, Kourampa, Jenny, Meadows, Anne, O’Brien, Criona, Price, Jane, Publico, Cherry, Rastall, Rebecca, Ribeiro, Carla, Rowlands, Jane, Ruffolo, Valentina, Tordesillas, Hugo, Dunmore, Benjamin J., Gräf, Stefan, Hodgson, Josh, Huang, Christopher, Hunter, Kelvin, Jones, Emma, Legchenko, Ekaterina, Matara, Cecilia, Martin, Jennifer, O’Donnell, Ciara, Pointon, Linda, Shih, Joy, Sutcliffe, Rachel, Tilly, Tobias, Treacy, Carmen, Tong, Zhen, Wylot, Marta, Betancourt, Ariana, Bower, Georgie, Cossetti, Chiara, De Sa, Aloka, Epping, Madeline, Gleadall, Nick, Hinch, Andrew, Jackson, Sarah, Jarvis, Isobel, Krishna, Ben, Omarjee, Ommar, Perera, Marianne, Potts, Martin, Richoz, Nathan, Romashova, Veronika, Stefanucci, Luca, Strezlecki, Mateusz, Turner, Lori, De Bie, Eckart M.D.D., Bunclark, Katherine, Josipovic, Masa, Mackay, Michael, Allison, John, Butcher, Helen, Caputo, Daniela, Dewhurst, Eleanor, Furlong, Anita, Graves, Barbara, Gray, Jennifer, Ivers, Tasmin, Le Gresley, Emma, Linger, Rachel, Meloy, Sarah, Muldoon, Francesca, Ovington, Nigel, Papadia, Sofia, Stark, Hannah, Stirrups, Kathleen E., Townsend, Paul, Walker, Neil, Webster, Jennifer, Scholtes, Ingrid, Hein, Sabine, King, Rebecca, Bradley, John R., Smith, Kenneth G.C., Lee, Joo Hyeon, Gupta, Ravindra K.

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Human Cytomegalovirus Infection of Epithelial Cells Increases SARS-CoV-2 Superinfection by Upregulating the ACE2 Receptor von Perera, Marianne R, Greenwood, Edward J D, Crozier, Thomas W M, Elder, Elizabeth G, Schmitt, Janika, Crump, Colin M, Lehner, Paul J, Wills, Mark R, Sinclair, John H

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Neisseria montereyensis sp. nov., Isolated from Oropharynx of California Sea Lion (Zalophus californianus): Genomic, Phylogenetic, and Phenotypic Study von Volokhov, Dmitriy V., Zagorodnyaya, Tatiana A., Furtak, Vyacheslav A., Nattanmai, Geetha, Randall, Linnell, Jose, Sherly, Gao, Yamei, Gulland, Frances M., Eisenberg, Tobias, Delmonte, Pierluigi, Blom, Jochen, Mitchell, Kara K.

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Efficacy and safety of baricitinib or ravulizumab in adult patients with severe COVID-19 (TACTIC-R): a randomised, parallel-arm, open-label, phase 4 trial von Hall, Frances C, Cheriyan, Joseph, Galloway, James, Bond, Simon, Norton, Sam, Kostapanos, Michalis, Nodale, Marianna, Jayne, David R, Galloway, James, Wilkinson, Ian, Banham-Hall, Edward, Bayes, Hannah, Kostapanos, Michalis, Nodale, Marianna, Petchey, William, Nagra, Deepak, Bird, Georgina, Nye, Clemency, Britten, Vianne, Broad, Lauren, Frayling, Sharon, Gray, Laura, Haynes, Matthew, Oliver, Catherine, Ahmed, Tanwir, Byrne, Natalie, Hernan-Sancho, Elena, Stockley, Louise, Templin, Heike, Fisk, Marie, Gray, Joanna, Gudu, Tania, Kulkarni, Spoorthy, Masters, Peta, Mir, Fraz, Stober, Carmel, Abercrombie, Donna, Bermperi, Areti, Burns, Stella, Canna, Laura, Hodges, Kathy, Jose, Sherly, Kourampa, Evgenia, Meadows, Anne, Nacorda, Aileen, Pasquale, Ciro, Read, Debbie, Rowlands, Jane, Ruffulo, Valentina, Soave, Carlotta, Tordesillas, Hugo, Wright, Samantha, Scott, Kathryn, Cathcart, Susanne, Rimmer, Dominic, Semple, Gary, Sheeran, Tom, Phiri, Laurence, Bhagat, Shweta, Kellett, Jo, Bukhari, Marwan, Simpson, Kerry, Makkuni, Damodar, Patrick, Jean, Kavanagh, David, Barr, Andrew, Baldwin, Kelly, McAlinden, Paul, McCormack, Louise, Stephenson, Elaine, Cross, Elizabeth L A, Musiol, Monika, Cope, Andrew, Koduri, Gouri, Mercioniu, Mihaela, Kunhunny, Swapna, Pollard, Louise, Coakley, Gerald, Gupta, Sunil, Pilgrim, Samia, Treus, Estefania, Boehmer, Gabriele, Beranova, Eva, Knight, Alicia, Tilbey, Sorrell, Willis, Joanna, Putensen, Daniel, Dimitriadis, Georgios K, Gogoi, Sukanya, Griffiths, Nicola, Rajasekaran, Arvind, Nisar, Muhammad, Ustianowski, Andrew, Lindergard, Gabriella, Uriel, Alison, Hey, Samuel, Bruce, Michelle, Flaherty, Jan, Fox, Claire, Parfrey, Helen

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Author Correction: Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies von Collier, Dami A., De Marco, Anna, Ferreira, Isabella A. T. M., Meng, Bo, Datir, Rawlings P., Walls, Alexandra C., Kemp, Steven A., Bassi, Jessica, Pinto, Dora, Silacci-Fregni, Chiara, Bianchi, Siro, Tortorici, M. Alejandra, Bowen, John, Culap, Katja, Jaconi, Stefano, Cameroni, Elisabetta, Snell, Gyorgy, Pizzuto, Matteo S., Pellanda, Alessandra Franzetti, Garzoni, Christian, Riva, Agostino, Elmer, Anne, Kingston, Nathalie, Graves, Barbara, McCoy, Laura E., Smith, Kenneth G. C., Bradley, John R., Temperton, Nigel, Ceron-Gutierrez, Lourdes, Barcenas-Morales, Gabriela, Harvey, William, Virgin, Herbert W., Lanzavecchia, Antonio, Piccoli, Luca, Doffinger, Rainer, Wills, Mark, Veesler, David, Corti, Davide, Gupta, Ravindra K.

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Author Correction: SARS-CoV-2 evolution during treatment of chronic infection von Kemp, Steven A., Collier, Dami A., Datir, Rawlings P., Ferreira, Isabella A. T. M., Gayed, Salma, Jahun, Aminu, Hosmillo, Myra, Rees-Spear, Chloe, Mlcochova, Petra, Lumb, Ines Ushiro, Roberts, David J., Chandra, Anita, Temperton, Nigel, Sharrocks, Katherine, Blane, Elizabeth, Modis, Yorgo, Leigh, Kendra E., Briggs, John A. G., van Gils, Marit J., Smith, Kenneth G. C., Bradley, John R., Smith, Chris, Doffinger, Rainer, Ceron-Gutierrez, Lourdes, Barcenas-Morales, Gabriela, Pollock, David D., Goldstein, Richard A., Smielewska, Anna, Skittrall, Jordan P., Gouliouris, Theodore, Goodfellow, Ian G., Gkrania-Klotsas, Effrossyni, Illingworth, Christopher J. R., McCoy, Laura E., Gupta, Ravindra K.

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Complement lectin pathway activation is associated with COVID-19 disease severity, independent of MBL2 genotype subgroups von Hurler, Lisa, Szilágyi, Ágnes, Mescia, Federica, Bergamaschi, Laura, Mező, Blanka, Sinkovits, György, Réti, Marienn, Müller, Veronika, Iványi, Zsolt, Gál, János, Gopcsa, László, Reményi, Péter, Szathmáry, Beáta, Lakatos, Botond, Szlávik, János, Bobek, Ilona, Prohászka, Zita Z, Förhécz, Zsolt, Csuka, Dorottya, Kajdácsi, Erika, Cervenak, László, Kiszel, Petra, Masszi, Tamás, Vályi-Nagy, István, Würzner, Reinhard, Lyons, Paul A, Toonen, Erik J M, Prohászka, Zoltán

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Combined Point-of-Care Nucleic Acid and Antibody Testing for SARS-CoV-2 following Emergence of D614G Spike Variant von Mlcochova, Petra, Collier, Dami, Ritchie, Allyson, Assennato, Sonny M., Hosmillo, Myra, Goel, Neha, Chatterjee, Krishna, Mendoza, Vivien, Temperton, Nigel, Kiss, Leo, Ciazynska, Katarzyna A., Xiong, Xiaoli, Barmpounakis, Petros, Demeris, Nikos, Skells, Richard, Bradley, John, Baker, Steven, Wilson, Michael, Amoroso, Glenn, Gkrania-Klotsas, Effrosyni, Gupta, Ravindra K., Bradley, John, Dougan, Gordon, Goodfellow, Ian, Gupta, Ravi, Lehner, Paul J., Lyons, Paul, Matheson, Nicholas J., Smith, Kenneth G.C., Toshner, Mark, Weekes, Michael P., Brown, Nick, Curran, Martin, Palmar, Surendra, Chapman, Daniel, Shaw, Ashley, Bermperi, Areti, Worsley, Jieniean, de Jesus, Ranalie, Vergese, Bensi, Vargas, Phoebe, Fabiculana, Marivic, Perales, Marlyn, Mynott, Lee, Bates, Amy, Williams, Alexandra, Phillips, David, Overhill, Alex, Sipple, Jamal, Frost, Steven, Knock, Helena, Rundell, Viona, Abeseabe, Richmond, Vicente, Isabel, Rowlands, Jane, O’Brien, Criona, Rastall, Rebecca, Hewitt, Sarah, Calder, Jo, Graves, Barbara, Caputo, Daniela, Le Gresley, Emma, Martin, Jennifer, Legchenko, Ekaterina, Huang, Christopher, Sutcliffe, Rachel, Hodgson, Josh, Shih, Joy, Graf, Stefan, Tong, Zhen, Hunter, Kelvin, Wylot, Marta, Fawke, Stuart, Bullman, Ben, Jarvis, Isobel, Omarjee, Ommar, De Sa, Aloka, Marsden, Joe, Betancourt, Ariana, Richoz, Nathan, Sharma, Rahul, Nice, Francesca, Huhn, Oisin, Savoinykh Yarkoni, Natalia, Lewis, Daniel, Cossetti, Chiara, Walker, Neil, Stirrups, Kathy, Ovington, Nigel, Li, Emily, Papadia, Sofia, Torok, Estee, Hall, Grant, Jahun, Aminu, Chaudhry, Yasmin, Yakovleva, Anna, Feltwell, Theresa, Khokhar, Fahad, Holdcroft, Charlotte, Parmar, Surendra

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Point of Care Nucleic Acid Testing for SARS-CoV-2 in Hospitalized Patients: A Clinical Validation Trial and Implementation Study von Collier, Dami A., Assennato, Sonny M., Warne, Ben, Sithole, Nyarie, Sharrocks, Katherine, Ritchie, Allyson, Ravji, Pooja, Routledge, Matthew, Sparkes, Dominic, Skittrall, Jordan, Smielewska, Anna, Ramsey, Isobel, Goel, Neha, Curran, Martin, Enoch, David, Tassell, Rhys, Lineham, Michelle, Vaghela, Devan, Leong, Clare, Mok, Hoi Ping, Bradley, John, Smith, Kenneth G.C., Mendoza, Vivienne, Demiris, Nikos, Besser, Martin, Dougan, Gordon, Lehner, Paul J., Siedner, Mark J., Zhang, Hongyi, Waddington, Claire S., Lee, Helen, Gupta, Ravindra K., Baker, Stephen, Bradley, John, Dougan, Gordon, Goodfellow, Ian, Gupta, Ravindra K., Lehner, Paul J., Lyons, Paul, Matheson, Nicholas J., Smith, Kenneth G.C., Toshner, Mark, Weekes, Michael P., Brown, Nick, Curran, Martin, Palmar, Surendra, Zhang, Hongyi, Enoch, David, Chapman, Daniel, Shaw, Ashley, Mendoza, Vivien, Jose, Sherly, Bermperi, Areti, Zerrudo, Julie Ann, Kourampa, Evgenia, Saunders, Caroline, de Jesus, Ranalie, Domingo, Jason, Pasquale, Ciro, Vergese, Bensi, Vargas, Phoebe, Fabiculana, Marivic, Perales, Marlyn, Skells, Richard, Mynott, Lee, Blake, Elizabeth, Bates, Amy, Vallier, Anne-laure, Williams, Alexandra, Phillips, David, Chiu, Edmund, Overhill, Alex, Ramenante, Nicola, Sipple, Jamal, Frost, Steven, Knock, Helena, Hardy, Richard, Foster, Emily, Davidson, Fiona, Rundell, Viona, Bundi, Purity, Abeseabe, Richmond, Clark, Sarah, Vicente, Isabel

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Levels of soluble complement regulators predict severity of COVID-19 symptoms von Tierney, Anna L, Alali, Wajd Mohammed, Scott, Thomas, Rees-Unwin, Karen S, Clark, Simon J, Unwin, Richard D

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