A Hybrid Structural Approach to Analyze Ligand Binding by the Serotonin Type 4 Receptor (5-HT4) von Padayatti, Pius S., Wang, Liwen, Gupta, Sayan, Orban, Tivadar, Sun, Wenyu, Salom, David, Jordan, Steven R., Palczewski, Krzysztof, Chance, Mark R.

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A Nucleic Acid Triple Helix Formed by a Peptide Nucleic Acid-DNA Complex von Betts, Laurie, Josey, John A., Veal, James M., Jordan, Steven R.

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Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors von Lloyd, David J., St Jean, David J., Kurzeja, Robert J. M., Wahl, Robert C., Michelsen, Klaus, Cupples, Rod, Chen, Michelle, Wu, John, Sivits, Glenn, Helmering, Joan, Komorowski, Renée, Ashton, Kate S., Pennington, Lewis D., Fotsch, Christopher, Vazir, Mukta, Chen, Kui, Chmait, Samer, Zhang, Jiandong, Liu, Longbin, Norman, Mark H., Andrews, Kristin L., Bartberger, Michael D., Van, Gwyneth, Galbreath, Elizabeth J., Vonderfecht, Steven L., Wang, Minghan, Jordan, Steven R., Véniant, Murielle M., Hale, Clarence

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Small Molecule Disruptors of the Glucokinase–Glucokinase Regulatory Protein Interaction: 3. Structure–Activity Relationships within the Aryl Carbinol Region of the N‑Arylsulfonamid... von Nishimura, Nobuko, Norman, Mark H, Liu, Longbin, Yang, Kevin C, Ashton, Kate S, Bartberger, Michael D, Chmait, Samer, Chen, Jie, Cupples, Rod, Fotsch, Christopher, Helmering, Joan, Jordan, Steven R, Kunz, Roxanne K, Pennington, Lewis D, Poon, Steve F, Siegmund, Aaron, Sivits, Glenn, Lloyd, David J, Hale, Clarence, St. Jean, David J

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Crystal Structure of the Ribonuclease H Domain of HIV-1 Reverse Transcriptase von Davies, Jay F., Hostomska, Zuzana, Hostomsky, Zdenek, Jordan, Steven R., Matthews, David A.

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Discovery and Structure-Guided Optimization of Diarylmethanesulfonamide Disrupters of Glucokinase–Glucokinase Regulatory Protein (GK–GKRP) Binding: Strategic Use of a N → S (nN → σ... von Pennington, Lewis D, Bartberger, Michael D, Croghan, Michael D, Andrews, Kristin L, Ashton, Kate S, Bourbeau, Matthew P, Chen, Jie, Chmait, Samer, Cupples, Rod, Fotsch, Christopher, Helmering, Joan, Hong, Fang-Tsao, Hungate, Randall W, Jordan, Steven R, Kong, Ke, Liu, Longbin, Michelsen, Klaus, Moyer, Carolyn, Nishimura, Nobuko, Norman, Mark H, Reichelt, Andreas, Siegmund, Aaron C, Sivits, Glenn, Tadesse, Seifu, Tegley, Christopher M, Van, Gwyneth, Yang, Kevin C, Yao, Guomin, Zhang, Jiandong, Lloyd, David J, Hale, Clarence, St. Jean, David J

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Small Molecule Disruptors of the Glucokinase–Glucokinase Regulatory Protein Interaction: 5. A Novel Aryl Sulfone Series, Optimization Through Conformational Analysis von Tamayo, Nuria A, Norman, Mark H, Bartberger, Michael D, Hong, Fang-Tsao, Bo, Yunxin, Liu, Longbin, Nishimura, Nobuko, Yang, Kevin C, Tadesse, Seifu, Fotsch, Christopher, Chen, Jie, Chmait, Samer, Cupples, Rod, Hale, Clarence, Jordan, Steven R, Lloyd, David J, Sivits, Glenn, Van, Gwyneth, St. Jean, David J

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Structure of the Lambda Complex at 2.5 Å Resolution: Details of the Repressor-Operator Interactions von Jordan, Steven R., Pabo, Carl O.

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Small Molecule Disruptors of the Glucokinase–Glucokinase Regulatory Protein Interaction: 2. Leveraging Structure-Based Drug Design to Identify Analogues with Improved Pharmacokinet... von St. Jean, David J., Ashton, Kate S., Bartberger, Michael D., Chen, Jie, Chmait, Samer, Cupples, Rod, Galbreath, Elizabeth, Helmering, Joan, Hong, Fang-Tsao, Jordan, Steven R., Liu, Longbin, Kunz, Roxanne K., Michelsen, Klaus, Nishimura, Nobuko, Pennington, Lewis D., Poon, Steve F., Reid, Darren, Sivits, Glenn, Stec, Markian M., Tadesse, Seifu, Tamayo, Nuria, Van, Gwyneth, Yang, Kevin C., Zhang, Jiandong, Norman, Mark H., Fotsch, Christopher, Lloyd, David J., Hale, Clarence

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Crystal Structures of Recombinant 19-kDa Human Fibroblast Collagenase Complexed to Itself von Lovejoy, Brett, Hassell, Anne M, Luther, Michael A, Weigl, Debra, Jordan, Steven R

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Small Molecule Disruptors of the Glucokinase–Glucokinase Regulatory Protein Interaction: 4. Exploration of a Novel Binding Pocket von Hong, Fang-Tsao, Norman, Mark H, Ashton, Kate S, Bartberger, Michael D, Chen, Jie, Chmait, Samer, Cupples, Rod, Fotsch, Christopher, Jordan, Steven R, Lloyd, David J, Sivits, Glenn, Tadesse, Seifu, Hale, Clarence, St. Jean, David J

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Hydroxyethylamine-based inhibitors of BACE1: P1–P3 macrocyclization can improve potency, selectivity, and cell activity von Pennington, Lewis D., Whittington, Douglas A., Bartberger, Michael D., Jordan, Steven R., Monenschein, Holger, Nguyen, Thomas T., Yang, Bryant H., Xue, Qiufen M., Vounatsos, Filisaty, Wahl, Robert C., Chen, Kui, Wood, Stephen, Citron, Martin, Patel, Vinod F., Hitchcock, Stephen A., Zhong, Wenge

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2-Amino-1,3-thiazol-4(5H)-ones as Potent and Selective 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors: Enzyme−Ligand Co-Crystal Structure and Demonstration of Pharmacodynamic E... von Johansson, Lars, Fotsch, Christopher, Bartberger, Michael D, Castro, Victor M, Chen, Michelle, Emery, Maurice, Gustafsson, Sonja, Hale, Clarence, Hickman, Dean, Homan, Evert, Jordan, Steven R, Komorowski, Renee, Li, Aiwen, McRae, Kenneth, Moniz, George, Matsumoto, Guy, Orihuela, Carlos, Palm, Gunnar, Veniant, Murielle, Wang, Minghan, Williams, Meredith, Zhang, Jiandong

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Crystal Structure of Murine 11β-Hydroxysteroid Dehydrogenase 1:  An Important Therapeutic Target for Diabetes von Zhang, Jiandong, Osslund, Timothy D, Plant, Matthew H, Clogston, Christi L, Nybo, Rebecca E, Xiong, Fei, Delaney, John M, Jordan, Steven R

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A novel dimer configuration revealed by the crystal structure at 2.4 resolution of human interleukin-5 von Milburn, Michael V, Hassell, Anne M, Lambert, Millard H, Jordan, Steven R, Proudfoot, Amanda E. I, Graber, Pierre, Wells, Timothy N. C

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Structure of the Catalytic Domain of Fibroblast Collagenase Complexed with an Inhibitor von Lovejoy, Brett, Cleasby, Anne, Hassell, Anne M., Longley, Kelly, Luthe, Michael A., Weigl, Debra, McGeehan, Gerard, McElroy, Andrew B., Drewry, David, Lambert, Millard H., Jordan, Steven R.

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Design and synthesis of novel 6,7-imidazotetrahydroquinoline inhibitors of thymidylate synthase using iterative protein crystal structure analysis von Reich, Siegfried H, Fuhry, Mary Ann M, Nguyen, Dzuy, Pino, Mark J, Welsh, Katherine M, Webber, Stephanie, Janson, Cheryl A, Jordan, Steven R, Matthews, David A

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Peptide Ligands of pp60c-src SH2 Domains:  A Thermodynamic and Structural Study von Charifson, Paul S, Shewchuk, Lisa M, Rocque, Warren, Hummel, Conrad W, Jordan, Steven R, Mohr, Christopher, Pacofsky, Gregory J, Peel, Michael R, Rodriguez, Marc, Sternbach, Daniel D, Consler, Thomas G

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Conserved Residues Make Similar Contacts in Two Repressor-Operator Complexes von Pabo, Carl O., Aggarwal, Aneel K., Jordan, Steven R., Beamer, Lesa J., Obeysekare, Upul R., Harrison, Stephen C.

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Potent Dipeptide Inhibitors of the pp60 c - src SH2 Domain von Pacofsky, Gregory J, Lackey, Karen, Alligood, Krystal J, Berman, Judd, Charifson, Paul S, Crosby, Renae M, Dorsey, George F, Feldman, Paul L, Gilmer, Tona M, Hummel, Conrad W, Jordan, Steven R, Mohr, Christopher, Shewchuk, Lisa M, Sternbach, Daniel D, Rodriguez, Marc

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