TIGIT can inhibit T cell activation via ligation-induced nanoclusters, independent of CD226 co-stimulation von Worboys, Jonathan D., Vowell, Katherine N., Hare, Roseanna K., Ambrose, Ashley R., Bertuzzi, Margherita, Conner, Michael A., Patel, Florence P., Zammit, William H., Gali-Moya, Judit, Hazime, Khodor S., Jones, Katherine L., Rey, Camille, Jonjic, Stipan, Rovis, Tihana Lenac, Tannahill, Gillian M., Cruz De Matos, Gabriela Dos Santos, Waight, Jeremy D., Davis, Daniel M.

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Discovery of a Novel Bromodomain and Extra Terminal Domain (BET) Protein Inhibitor, I-BET282E, Suitable for Clinical Progression von Jones, Katherine L, Beaumont, Dominic M, Bernard, Sharon G, Bit, Rino A, Campbell, Simon P, Chung, Chun-Wa, Cutler, Leanne, Demont, Emmanuel H, Dennis, Kate, Gordon, Laurie, Gray, James R, Haase, Michael V, Lewis, Antonia J, McCleary, Scott, Mitchell, Darren J, Moore, Susanne M, Parr, Nigel, Robb, Olivia J, Smithers, Nicholas, Soden, Peter E, Suckling, Colin J, Taylor, Simon, Walker, Ann L, Watson, Robert J, Prinjha, Rab K

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Dissecting the role of adult hippocampal neurogenesis towards resilience versus susceptibility to stress-related mood disorders von Jones, Katherine L., Zhou, Mei, Jhaveri, Dhanisha J.

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A protocol to develop clinical guidelines for inclusion-body myositis von Jones, Katherine L., Sejersen, Thomas, Amato, Anthony A., Hilton-Jones, David, Schmidt, Jens, Wallace, Amanda C., Badrising, Umesh A., Rose, Michael R.

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Microplastic accumulation in a Zostera marina L. bed at Deerness Sound, Orkney, Scotland von Jones, Katherine L., Hartl, Mark G.J., Bell, Michael C., Capper, Angela

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Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3‑Kinase δ for the Treatment of Respiratory Disease von Down, Kenneth, Amour, Augustin, Baldwin, Ian R, Cooper, Anthony W. J, Deakin, Angela M, Felton, Leigh M, Guntrip, Stephen B, Hardy, Charlotte, Harrison, Zoë A, Jones, Katherine L, Jones, Paul, Keeling, Suzanne E, Le, Joelle, Livia, Stefano, Lucas, Fiona, Lunniss, Christopher J, Parr, Nigel J, Robinson, Ed, Rowland, Paul, Smith, Sarah, Thomas, Daniel A, Vitulli, Giovanni, Washio, Yoshiaki, Hamblin, J. Nicole

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Discovery of a Potent, Cell Penetrant, and Selective p300/CBP-Associated Factor (PCAF)/General Control Nonderepressible 5 (GCN5) Bromodomain Chemical Probe von Humphreys, Philip G, Bamborough, Paul, Chung, Chun-wa, Craggs, Peter D, Gordon, Laurie, Grandi, Paola, Hayhow, Thomas G, Hussain, Jameed, Jones, Katherine L, Lindon, Matthew, Michon, Anne-Marie, Renaux, Jessica F, Suckling, Colin J, Tough, David F, Prinjha, Rab K

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The experience of treatment barriers and their influence on quality of life in American Indian/Alaska Native breast cancer survivors von Goodwin, Elizabeth A., Burhansstipanov, Linda, Dignan, Mark, Jones, Katherine L., Kaur, Judith Salmon

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Identification and Optimization of a Ligand-Efficient Benzoazepinone Bromodomain and Extra Terminal (BET) Family Acetyl-Lysine Mimetic into the Oral Candidate Quality Molecule I‑BE... von Humphreys, Philip G., Anderson, Niall A., Bamborough, Paul, Baxter, Andrew, Chung, Chun-wa, Cookson, Rosa, Craggs, Peter D., Dalton, Toryn, Fournier, Julie C. L., Gordon, Laurie J., Gray, Heather F., Gray, Matthew W., Gregory, Richard, Hirst, David J., Jamieson, Craig, Jones, Katherine L., Kessedjian, Hripsimee, Lugo, David, McGonagle, Grant, Patel, Vipulkumar K., Patten, Christopher, Poole, Darren L., Prinjha, Rab K., Ramirez-Molina, Cesar, Rioja, Inmaculada, Seal, Gail, Stafford, Kayleigh A. J., Shah, Rishi R., Tape, Daniel, Theodoulou, Natalie H., Tomlinson, Laura, Ukuser, Sabri, Wall, Ian D., Wellaway, Natalie, White, Gemma

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Structure- and Property-Based Optimization of Efficient Pan-Bromodomain and Extra Terminal Inhibitors to Identify Oral and Intravenous Candidate I‑BET787 von Hirst, David J., Bamborough, Paul, Al-Mahdi, Niam, Angell, Davina C., Barnett, Heather A., Baxter, Andrew, Bit, Rino A., Brown, Jack A., Chung, Chun-wa, Craggs, Peter D., Davis, Robert P., Demont, Emmanuel H., Ferrie, Alan, Gordon, Laurie J., Harada, Isobel, Ho, Tim C. T., Holyer, Ian D., Hooper-Greenhill, Edward, Jones, Katherine L., Lindon, Matthew J., Lovatt, Cerys, Lugo, David, Maller, Claire, McGonagle, Grant, Messenger, Cassie, Mitchell, Darren J., Pascoe, David D., Patel, Vipulkumar K., Patten, Christopher, Poole, Darren L., Shah, Rishi R., Rioja, Inmaculada, Stafford, Kayleigh A. J., Tape, Daniel, Taylor, Simon, Theodoulou, Natalie H., Tomlinson, Laura, Wall, Ian D., Wellaway, Christopher R., White, Gemma, Prinjha, Rab K., Humphreys, Philip G.

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Direct, Late‐Stage Mono‐N‐arylation of Pentamidine: Method Development, Mechanistic Insight, and Expedient Access to Novel Antiparastitics against Diamidine‐Resistant Parasites... von Robertson, Jack, Ungogo, Marzuq A., Aldfer, Mustafa M., Lemgruber, Leandro, McWhinnie, Fergus S., Bode, Bela E., Jones, Katherine L., Watson, Allan J. B., Koning, Harry P., Burley, Glenn A.

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p38α Mitogen-Activated Protein Kinase Inhibitors: Optimization of a Series of Biphenylamides to Give a Molecule Suitable for Clinical Progression von Aston, Nicola M, Bamborough, Paul, Buckton, Jacqueline B, Edwards, Christopher D, Holmes, Duncan S, Jones, Katherine L, Patel, Vipulkumar K, Smee, Penny A, Somers, Donald O, Vitulli, Giovanni, Walker, Ann L

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Biphenyl amide p38 kinase inhibitors 3: Improvement of cellular and in vivo activity von Angell, Richard, Aston, Nicola M., Bamborough, Paul, Buckton, Jacky B., Cockerill, Stuart, deBoeck, Suzanne J., Edwards, Chris D., Holmes, Duncan S., Jones, Katherine L., Laine, Dramane I., Patel, Shila, Smee, Penny A., Smith, Kathryn J., Somers, Don O., Walker, Ann L.

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Biphenyl amide p38 kinase inhibitors 4: DFG-in and DFG-out binding modes von Angell, Richard M., Angell, Tony D., Bamborough, Paul, Bamford, Mark J., Chung, Chun-wa, Cockerill, Stuart G., Flack, Stephen S., Jones, Katherine L., Laine, Dramane I., Longstaff, Timothy, Ludbrook, Steve, Pearson, Rosannah, Smith, Kathryn J., Smee, Penny A., Somers, Don O., Walker, Ann L.

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Biphenyl amide p38 kinase inhibitors 1: Discovery and binding mode von Angell, Richard M., Bamborough, Paul, Cleasby, Anne, Cockerill, Stuart G., Jones, Katherine L., Mooney, Christopher J., Somers, Donald O., Walker, Ann L.

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A Comparison of Quality of Life Between Native and Non-Native Cancer Survivors: Native and Non-Native Cancer Survivors’ QOL von Burhansstipanov, Linda, Dignan, Mark, Jones, Katherine L., Krebs, Linda U., Marchionda, Paula, Kaur, Judith Salmon

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Evaluating the two-component inspection model in a simplified luggage search task von Wales, Alan W. J., Anderson, Clare, Jones, Katherine L., Schwaninger, Adrian, Horne, James A.

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Biphenyl amide p38 kinase inhibitors 2: Optimisation and SAR von Angell, Richard M., Angell, Tony D., Bamborough, Paul, Brown, David, Brown, Murray, Buckton, Jacky B., Cockerill, Stuart G., Edwards, Chris D., Jones, Katherine L., Longstaff, Tim, Smee, Penny A., Smith, Kathryn J., Somers, Don O., Walker, Ann L., Willson, Malcolm

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Discovery of a Bromodomain and Extraterminal Inhibitor with a Low Predicted Human Dose through Synergistic Use of Encoded Library Technology and Fragment Screening von Wellaway, Christopher R, Amans, Dominique, Bamborough, Paul, Barnett, Heather, Bit, Rino A, Brown, Jack A, Carlson, Neil R, Chung, Chun-wa, Cooper, Anthony W. J, Craggs, Peter D, Davis, Robert P, Dean, Tony W, Evans, John P, Gordon, Laurie, Harada, Isobel L, Hirst, David J, Humphreys, Philip G, Jones, Katherine L, Lewis, Antonia J, Lindon, Matthew J, Lugo, Dave, Mahmood, Mahnoor, McCleary, Scott, Medeiros, Patricia, Mitchell, Darren J, O’Sullivan, Michael, Le Gall, Armelle, Patel, Vipulkumar K, Patten, Chris, Poole, Darren L, Shah, Rishi R, Smith, Jane E, Stafford, Kayleigh A. J, Thomas, Pamela J, Vimal, Mythily, Wall, Ian D, Watson, Robert J, Wellaway, Natalie, Yao, Gang, Prinjha, Rab K

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Attenuation of Barium, Strontium, Cobalt, and Nickel Plumes Formed during Microbial Iron Reduction in a Crude-Oil-Contaminated Aquifer von Jones, Katherine L., Ziegler, Brady A., Davis, Audrey M., Cozzarelli, Isabelle M.

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