Ube3a unsilencer for the potential treatment of Angelman syndrome von Vihma, Hanna, Li, Kelin, Welton-Arndt, Anna, Smith, Audrey L., Bettadapur, Kiran R., Gilmore, Rachel B., Gao, Eric, Cotney, Justin L., Huang, Hsueh-Cheng, Collins, Jon L., Chamberlain, Stormy J., Lee, Hyeong-Min, Aubé, Jeffrey, Philpot, Benjamin D.

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Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120) von Sparks, Steven M., Chen, Grace, Collins, Jon L., Danger, Dana, Dock, Steven T., Jayawickreme, Channa, Jenkinson, Stephen, Laudeman, Christopher, Leesnitzer, M. Anthony, Liang, Xi, Maloney, Patrick, McCoy, David C., Moncol, David, Rash, Vincent, Rimele, Thomas, Vulimiri, Padmaja, Way, James M., Ross, Sean

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Synthetic LXR Ligand Inhibits the Development of Atherosclerosis in Mice von Joseph, Sean B., McKilligin, Elaine, Pei, Liming, Watson, Michael A., Collins, Alan R., Laffitte, Bryan A., Chen, Mingyi, Noh, Grace, Goodman, Joanne, Hagger, Graham N., Tran, Jonathan, Tippin, Tim K., Wang, Xuping, Lusis, Aldons J., Hsueh, Willa A., Law, Ronald E., Collins, Jon L., Willson, Timothy M., Tontonoz, Peter

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Direct and Indirect Mechanisms for Regulation of Fatty Acid Synthase Gene Expression by Liver X Receptors von Joseph, Sean B., Laffitte, Bryan A., Patel, Parthive H., Watson, Michael A., Matsukuma, Karen E., Walczak, Robert, Collins, Jon L., Osborne, Timothy F., Tontonoz, Peter

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Activation of Liver X Receptor Improves Glucose Tolerance through Coordinate Regulation of Glucose Metabolism in Liver and Adipose Tissue von Laffitte, Bryan A., Chao, Lily C., Li, Jing, Walczak, Robert, Hummasti, Sarah, Joseph, Sean B., Castrillo, Antonio, Wilpitz, Damien C., Mangelsdorf, David J., Collins, Jon L., Saez, Enrique, Tontonoz, Peter

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The Nuclear Receptor Superfamily and Drug Discovery von Moore, John T., Collins, Jon L., Pearce, Kenneth H.

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The Human Nuclear Xenobiotic Receptor PXR: Structural Determinants of Directed Promiscuity von Watkins, Ryan E., Wisely, G. Bruce, Moore, Linda B., Collins, Jon L., Lambert, Millard H., Williams, Shawn P., Willson, Timothy M., Kliewer, Steven A., Redinbo, Matthew R.

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Identification of a Novel Human Constitutive Androstane Receptor (CAR) Agonist and Its Use in the Identification of CAR Target Genes von Maglich, Jodi M., Parks, Derek J., Moore, Linda B., Collins, Jon L., Goodwin, Bryan, Billin, Andrew N., Stoltz, Catherine A., Kliewer, Steven A., Lambert, Millard H., Willson, Timothy M., Moore, John T.

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Functional Consequences of Cysteine Modification in the Ligand Binding Sites of Peroxisome Proliferator Activated Receptors by GW9662 von Leesnitzer, Lisa M, Parks, Derek J, Bledsoe, Randy K, Cobb, Jeff E, Collins, Jon L, Consler, Thomas G, Davis, Roderick G, Hull-Ryde, Emily A, Lenhard, James M, Patel, Lisa, Plunket, Kelli D, Shenk, Jennifer L, Stimmel, Julie B, Therapontos, Christina, Willson, Timothy M, Blanchard, Steven G

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Structural Disorder in the Complex of Human Pregnane X Receptor and the Macrolide Antibiotic Rifampicin von Chrencik, Jill E, Orans, Jillian, Moore, Linda B, Xue, Yu, Peng, Li, Collins, Jon L, Wisely, G. Bruce, Lambert, Millard H, Kliewer, Steven A, Redinbo, Matthew R

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Discovery of Tertiary Sulfonamides as Potent Liver X Receptor Antagonists von Zuercher, William J, Buckholz, Richard G, Campobasso, Nino, Collins, Jon L, Galardi, Cristin M, Gampe, Robert T, Hyatt, Stephen M, Merrihew, Susan L, Moore, John T, Oplinger, Jeffrey A, Reid, Paul R, Spearing, Paul K, Stanley, Thomas B, Stewart, Eugene L, Willson, Timothy M

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Crystal structure of the PXR–T1317 complex provides a scaffold to examine the potential for receptor antagonism von Xue, Yu, Chao, Esther, Zuercher, William J., Willson, Timothy M., Collins, Jon L., Redinbo, Matthew R.

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The Phytoestrogen Coumestrol Is a Naturally Occurring Antagonist of the Human Pregnane X Receptor von Wang, Hongwei, Li, Hao, Moore, Linda B, Johnson, Michael D. L, Maglich, Jodi M, Goodwin, Bryan, Ittoop, Olivia R. R, Wisely, Bruce, Creech, Katrina, Parks, Derek J, Collins, Jon L, Willson, Timothy M, Kalpana, Ganjam V, Venkatesh, Madhukumar, Xie, Wen, Cho, Sool Y, Roboz, John, Redinbo, Matthew, Moore, John T, Mani, Sridhar

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Identification of a Nonsteroidal Liver X Receptor Agonist through Parallel Array Synthesis of Tertiary Amines von Collins, Jon L, Fivush, Adam M, Watson, Michael A, Galardi, Cristin M, Lewis, Michael C, Moore, Linda B, Parks, Derek J, Wilson, Joan G, Tippin, Tim K, Binz, Jane G, Plunket, Kelli D, Morgan, Daniel G, Beaudet, Elizabeth J, Whitney, Karl D, Kliewer, Steven A, Willson, Timothy M

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Identification of Bile Acid Precursors as Endogenous Ligands for the Nuclear Xenobiotic Pregnane X Receptor von Goodwin, Bryan, Gauthier, Karine C., Umetani, Michihisa, Watson, Michael A., Lochansky, Matthew I., Collins, Jon L., Leitersdorf, Eran, Mangelsdorf, David J., Kliewer, Steven A., Repa, Joyce J.

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Liver X Receptor Activators Display Anti-Inflammatory Activity in Irritant and Allergic Contact Dermatitis Models: Liver-X-Receptor-Specific Inhibition of Inflammation and Primary... von Fowler, Ashley J., Sheu, Mary Y., Schmuth, Matthias, Kao, Jack, Fluhr, Joachim W., Rhein, Linda, Collins, Jon L., Willson, Timothy M., Mangelsdorf, David J., Elias, Peter M., Feingold, Kenneth R.

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Novel Role for the Liver X Nuclear Receptor in the Suppression of Lung Inflammatory Responses von Birrell, Mark A., Catley, Matthew C., Hardaker, Elizabeth, Wong, Sissie, Willson, Timothy M., McCluskie, Kerryn, Leonard, Thomas, Farrow, Stuart N., Collins, Jon L., Haj-Yahia, Saleem, Belvisi, Maria G.

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ApoE Promotes the Proteolytic Degradation of Aβ von Jiang, Qingguang, Lee, C.Y. Daniel, Mandrekar, Shweta, Wilkinson, Brandy, Cramer, Paige, Zelcer, Noam, Mann, Karen, Lamb, Bruce, Willson, Timothy M., Collins, Jon L., Richardson, Jill C., Smith, Jonathan D., Comery, Thomas A., Riddell, David, Holtzman, David M., Tontonoz, Peter, Landreth, Gary E.

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Regulation of Cholesterol Homeostasis by the Liver X Receptors in the Central Nervous System von Whitney, Karl D, Watson, Michael A, Collins, Jon L, Benson, William G, Stone, Tammy M, Numerick, Mary Jo, Tippin, Timothy K, Wilson, Joan G, Winegar, Deborah A, Kliewer, Steven A

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Recruitment of FBXO22 for targeted degradation of NSD2 von Nie, David Y., Tabor, John R., Li, Jianping, Kutera, Maria, St-Germain, Jonathan, Hanley, Ronan P., Wolf, Esther, Paulakonis, Ethan, Kenney, Tristan M. G., Duan, Shili, Shrestha, Suman, Owens, Dominic D. G., Maitland, Matthew E. R., Pon, Ailing, Szewczyk, Magdalena, Lamberto, Anthony Joseph, Menes, Michael, Li, Fengling, Penn, Linda Z., Barsyte-Lovejoy, Dalia, Brown, Nicholas G., Barsotti, Anthony M., Stamford, Andrew W., Collins, Jon L., Wilson, Derek J., Raught, Brian, Licht, Jonathan D., James, Lindsey I., Arrowsmith, Cheryl H.

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