Cabozantinib (XL184), a novel MET and VEGFR2 inhibitor, simultaneously suppresses metastasis, angiogenesis, and tumor growth von Yakes, F Michael, Chen, Jason, Tan, Jenny, Yamaguchi, Kyoko, Shi, Yongchang, Yu, Peiwen, Qian, Fawn, Chu, Felix, Bentzien, Frauke, Cancilla, Belinda, Orf, Jessica, You, Andrew, Laird, A Douglas, Engst, Stefan, Lee, Lillian, Lesch, Justin, Chou, Yu-Chien, Joly, Alison H

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Inhibition of Tumor Cell Growth, Invasion, and Metastasis by EXEL-2880 (XL880, GSK1363089), a Novel Inhibitor of HGF and VEGF Receptor Tyrosine Kinases von FAWN QIAN, ENGST, Stefan, LOUGHEED, Julie, YAKSE, F. Michael, BENTZIEN, Frauke, WEI XU, ZAKS, Tal, WOOSTER, Richard, GRESHOCK, Joel, JOLY, Alison H, YAMAGUCHI, Kyoko, PEIWEN YU, WON, Kwang-Ai, MOCK, Lillian, LOU, Tracy, TAN, Jenny, CONNIE LI, TAM, Danny

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In Vitro and In Vivo Activity of Cabozantinib (XL184), an Inhibitor of RET, MET, and VEGFR2, in a Model of Medullary Thyroid Cancer von Bentzien, Frauke, Zuzow, Marcus, Heald, Nathan, Gibson, Anna, Shi, Yongchang, Goon, Leanne, Yu, Peiwen, Engst, Stefan, Zhang, Wentao, Huang, Donghui, Zhao, Lora, Vysotskaia, Valentina, Chu, Felix, Bautista, Rajana, Cancilla, Belinda, Lamb, Peter, Joly, Alison H., Yakes, F. Michael

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Inhibition of the T790M Gatekeeper Mutant of the Epidermal Growth Factor Receptor by EXEL-7647 von GENDREAU, Steven B, VENTURA, Richard, JACKMAN, Lisa, YONGCHANG SHI, PEIWEN YU, JING WANG, AFTAB, Dana T, JAEGER, Christopher T, MEYER, Stephanie M, DE COSTA, Anushka, ENGELL, Kelly, CHEN, Jason, KEAST, Paul, MARTINI, Jean-Francois, JOLY, Alison H, LAIRD, A. Douglas, YAKES, F. Michael, WENTAO ZHANG, BENTZIEN, Frauke, CANCILLA, Belinda, LUTMAN, Jeffery, CHU, Felix

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CTGF Expression is Induced by TGF- β in Cardiac Fibroblasts and Cardiac Myocytes: a Potential Role in Heart Fibrosis von Chen, Michelle M, Lam, Andrew, Abraham, Judith A, Schreiner, George F, Joly, Alison H

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Impaired angiogenesis in the remnant kidney model : I. Potential role of vascular endothelial growth factor and thrombospondin-1 von KANG, Duk-Hee, JOLY, Alison H, SCHREINER, George F, JOHNSON, Richard J, OH, Se-Woong, HUGO, Christian, KERJASCHKI, Dontscho, GORDON, Katherine L, MAZZALI, Marilda, JEFFERSON, J. Ashley, HUGHES, Jeremy, MADSEN, Kirsten M

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Advanced Glycosylation End Products Up-Regulate Connective Tissue Growth Factor (Insulin-Like Growth Factor-Binding Protein-Related Protein 2) in Human Fibroblasts: A Potential Mec... von Twigg, Stephen M., Chen, Michelle M., Joly, Alison H., Chakrapani, Sanjay D., Tsubaki, Junko, Kim, Ho-Seong, Oh, Youngman, Rosenfeld, Ron G.

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Connective Tissue Growth Factor/IGF-Binding Protein-Related Protein-2 Is a Mediator in the Induction of Fibronectin by Advanced Glycosylation End-Products in Human Dermal Fibroblas... von Twigg, Stephen M, Joly, Alison H, Chen, Michelle M, Tsubaki, Junko, Kim, Ho-Seong, Hwa, Vivian, Oh, Youngman, Rosenfeld, Ron G

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Inhibition of the mitogen activated protein kinase, p38α, prevents proinflammatory cytokine induction by human adherent mononuclear leukocytes in response to lipid loading von Feng, Ying, Schreiner, George F., Chakravarty, Sarvajit, Liu, David Y., Joly, Alison H.

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Insulin-like growth factor-binding protein-3 induces fetalization in neonatal rat cardiomyocytes von Henson, M, Damm, D, Lam, A, Garrard, L J, White, T, Abraham, J A, Schreiner, G F, Stanton, L W, Joly, A H

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Advanced Glycosylation End Products Up-Regulate Connective Tissue Growth Factor (Insulin-Like Growth Factor-Binding Protein-Related Protein 2) in Human Fibroblasts: A Potential Mec... von Twigg, Stephen M, Chen, Michelle M, Joly, Alison H, Chakrapani, Sanjay D, Tsubaki, Junko, Kim, Ho-Seong, Oh, Youngman, Rosenfeld, Ron G

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ZMIZ1 Variants Cause a Syndromic Neurodevelopmental Disorder von Carapito, Raphael, Ivanova, Ekaterina L., Morlon, Aurore, Meng, Linyan, Molitor, Anne, Erdmann, Eva, Kieffer, Bruno, Pichot, Angélique, Naegely, Lydie, Kolmer, Aline, Paul, Nicodème, Hanauer, Antoine, Tran Mau-Them, Frédéric, Jean-Marçais, Nolwenn, Hiatt, Susan M., Cooper, Gregory M., Tvrdik, Tatiana, Muir, Alison M., Dimartino, Clémantine, Chopra, Maya, Amiel, Jeanne, Gordon, Christopher T., Dutreux, Fabien, Garde, Aurore, Thauvin-Robinet, Christel, Wang, Xia, Leduc, Magalie S., Phillips, Meredith, Crawford, Heather P., Kukolich, Mary K., Hunt, David, Harrison, Victoria, Kharbanda, Mira, Smigiel, Robert, Gold, Nina, Hung, Christina Y., Viskochil, David H., Dugan, Sarah L., Bayrak-Toydemir, Pinar, Joly-Helas, Géraldine, Guerrot, Anne-Marie, Schluth-Bolard, Caroline, Rio, Marlène, Wentzensen, Ingrid M., McWalter, Kirsty, Schnur, Rhonda E., Lewis, Andrea M., Lalani, Seema R., Mensah-Bonsu, Noël, Céraline, Jocelyn, Sun, Zijie, Ploski, Rafal, Bacino, Carlos A., Mefford, Heather C., Faivre, Laurence, Bodamer, Olaf, Chelly, Jamel, Isidor, Bertrand, Bahram, Seiamak

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Identifying urban built environment factors in pregnancy care and maternal mental health outcomes von Zhang, Yiyel, Tayarani, Mohammad, Wang, Shuojia, Liu, Yifan, Sharma, Mohit, Joly, Rochelle, RoyChoudhury, Arindam, Hermann, Alison, Gao, Oliver H., Pathak, Jyotishman

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Exome sequencing identifies breast cancer susceptibility genes and defines the contribution of coding variants to breast cancer risk von Wilcox, Naomi, Dumont, Martine, González-Neira, Anna, Carvalho, Sara, Joly Beauparlant, Charles, Crotti, Marco, Luccarini, Craig, Soucy, Penny, Dubois, Stéphane, Nuñez-Torres, Rocio, Pita, Guillermo, Gardner, Eugene J., Dennis, Joe, Alonso, M. Rosario, Álvarez, Nuria, Baynes, Caroline, Collin-Deschesnes, Annie Claude, Desjardins, Sylvie, Becher, Heiko, Behrens, Sabine, Bolla, Manjeet K., Castelao, Jose E., Chang-Claude, Jenny, Cornelissen, Sten, Dörk, Thilo, Engel, Christoph, Gago-Dominguez, Manuela, Guénel, Pascal, Hadjisavvas, Andreas, Hahnen, Eric, Hartman, Mikael, Herráez, Belén, Jung, Audrey, Keeman, Renske, Kiechle, Marion, Li, Jingmei, Loizidou, Maria A., Lush, Michael, Michailidou, Kyriaki, Panayiotidis, Mihalis I., Sim, Xueling, Teo, Soo Hwang, Tyrer, Jonathan P., van der Kolk, Lizet E., Wahlström, Cecilia, Wang, Qin, Perry, John R. B., Benitez, Javier, Schmidt, Marjanka K., Schmutzler, Rita K., Pharoah, Paul D. P., Droit, Arnaud, Dunning, Alison M., Kvist, Anders, Devilee, Peter, Easton, Douglas F., Simard, Jacques

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ZMIZ1 Variants Cause a Syndromic Neurodevelopmental Disorder von Carapito, Raphael, Ivanova, Ekaterina L., Morlon, Aurore, Meng, Linyan, Molitor, Anne, Erdmann, Eva, Kieffer, Bruno, Pichot, Angélique, Naegely, Lydie, Kolmer, Aline, Paul, Nicodème, Hanauer, Antoine, Tran Mau-Them, Frédéric, Jean-Marçais, Nolwenn, Hiatt, Susan M., Cooper, Gregory M., Tvrdik, Tatiana, Muir, Alison M., Dimartino, Clémantine, Chopra, Maya, Amiel, Jeanne, Gordon, Christopher T., Dutreux, Fabien, Garde, Aurore, Thauvin-Robinet, Christel, Wang, Xia, Leduc, Magalie S., Phillips, Meredith, Crawford, Heather P., Kukolich, Mary K., Hunt, David, Harrison, Victoria, Kharbanda, Mira, Smigiel, Robert, Gold, Nina, Hung, Christina Y., Viskochil, David H., Dugan, Sarah L., Bayrak-Toydemir, Pinar, Joly-Helas, Géraldine, Guerrot, Anne-Marie, Schluth-Bolard, Caroline, Rio, Marlène, Wentzensen, Ingrid M., McWalter, Kirsty, Schnur, Rhonda E., Lewis, Andrea M., Lalani, Seema R., Mensah-Bonsu, Noël, Céraline, Jocelyn, Sun, Zijie, Ploski, Rafal, Bacino, Carlos A., Mefford, Heather C., Faivre, Laurence, Bodamer, Olaf, Chelly, Jamel, Isidor, Bertrand, Bahram, Seiamak

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Vertebrate genome evolution and the zebrafish gene map von Postlethwait, John H, Yan, Yi-Lin, Gates, Michael A, Horne, Sally, Amores, Angel, Brownlie, Alison, Donovan, Adriana, Egan, Elizabeth S, Force, Allan, Gong, Zhiyuan, Goutel, Carole, Fritz, Andreas, Kelsh, Robert, Knapik, Ela, Liao, Eric, Paw, Barry, Ransom, David, Singer, Amy, Thomson, Margaret, Abduljabbar, Tariq S, Yelick, Pam, Beier, Dave, Joly, J.-S, Larhammar, Dan, Rosa, Frederic, Westerfield, Monte, Zon, Leonard I, Johnson, Steve L, Talbot, William S

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Vascular endothelial growth factor (VEGF121) protects rats from renal infarction in thrombotic microangiopathy von Suga, Shin-Ichi, Kim, Yoon-Goo, Joly, Alison, Puchacz, Ela, Kang, Duk-Hee, Jefferson, J. Ashley, Abraham, Judith A., Hughes, Jeremy, Johnson, Richard J., Schreiner, George F.

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Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus von , Long, Jirong, Droit, Arnaud, Freeman, Adam, Milne, Roger L, Wang, Qin, Agata, Simona, Ahmed, Shahana, Aittomäki, Kristiina, Arason, Adalgeir, Arun, Banu K, Bacot, Francois, Barrowdale, Daniel, Beeghly-Fadiel, Alicia, Bermisheva, Marina, Bojesen, Stig E, Brand, Judith S, Brennan, Paul, Broeks, Annegien, Campbell, Ian, Chang-Claude, Jenny, Choi, Ji-Yeob, Claes, Kathleen B. M, Clarke, Christine, Cross, Simon S, Daly, Mary B, de la Hoya, Miguel, Devilee, Peter, Dorfling, Cecilia M, dos-Santos-Silva, Isabel, Dwek, Miriam, Egan, Kathleen, Eilber, Ursula, Einbeigi, Zakaria, Ejlertsen, Bent, Frost, Debra, Lalloo, Fiona, Figueroa, Jonine, Friedlander, Michael, Gambino, Gaetana, Garber, Judy, García-Closas, Montserrat, Gehrig, Andrea, Damiola, Francesca, Lesueur, Fabienne, González-Neira, Anna, Hallberg, Emily, Hansen, Thomas V. O, Hartman, Mikael, Hendricks, Carolyn B, Hillemanns, Peter, Imyanitov, Evgeny N, Jaworska-Bieniek, Katarzyna, John, Esther M, Jones, Michael, Kang, Daehee, Khusnutdinova, Elza, Knight, Julia A, Konstantopoulou, Irene, Laitman, Yael, Lambrechts, Diether, Lazaro, Conxi, Lee, Chuen Neng, Liljegren, Annelie, Lophatananon, Artitaya, Mannermaa, Arto, Matsuo, Keitaro, McGuffog, Lesley, Menegaux, Florence, Muir, Kenneth, Nathanson, Katherine L, Neuhausen, Susan L, Nussbaum, Robert L, Offit, Kenneth, Olah, Edith, Olopade, Olufunmilayo I, Peeters, Stephanie, Peterlongo, Paolo, Peto, Julian, Radice, Paolo, Rudolph, Anja, Sangrajrang, Suleeporn, Schmidt, Marjanka K, Schürmann, Peter, Shen, Chen-Yang, Shu, Xiao-Ou, Sigurdson, Alice, Slager, Susan, Soucy, Penny, Steinemann, Doris, Teo, Soo H, Terry, Mary Beth, Thomassen, Mads, Tihomirova, Laima, Tung, Nadine, Vijai, Joseph, Yannoukakos, Drakoulis, Pharoah, Paul D. P, Hall, Per, Dunning, Alison M

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Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus von Long, Jirong, Bolla, Manjeet K, Wang, Qin, Dennis, Joe, Agata, Simona, Aittomäki, Kristiina, Arason, Adalgeir, Arver, Brita, Beeghly-Fadiel, Alicia, Bermisheva, Marina, Blomqvist, Carl, Blot, William J, Bogdanova, Natalia V, Brauch, Hiltrud, Brennan, Paul, Cai, Qiuyin, Cox, Angela, Cross, Simon S, de la Hoya, Miguel, Domchek, Susan M, Dorfling, Cecilia M, Dumont, Martine, Dworniczak, Bernd, Eilber, Ursula, Ejlertsen, Bent, Frost, Debra, Lalloo, Fiona, Figueroa, Jonine, Friedlander, Michael, Gambino, Gaetana, Garber, Judy, García-Closas, Montserrat, Gehrig, Andrea, Damiola, Francesca, Lesueur, Fabienne, behalf of GEMO Study Collaborators, Godwin, Andrew K, Greene, Mark H, Hallberg, Emily, Hart, Steven, Hartman, Mikael, Verhoef, Senno, Hendricks, Carolyn B, Hulick, Peter J, Hunter, David J, Imyanitov, Evgeny N, Isaacs, Claudine, Jakubowska, Anna, Jaworska-Bieniek, Katarzyna, Jensen, Uffe Birk, Joly Beauparlant, Charles, Kabisch, Maria, Karlan, Beth Y, Kerin, Michael J, Knight, Julia A, Kwong, Ava, Laitman, Yael, Lambrechts, Diether, Lazaro, Conxi, Lee, Chuen Neng, Lee, Min Hyuk, Li, Jingmei, Lophatananon, Artitaya, Mai, Phuong L, Manoukian, Siranoush, Meindl, Alfons, Mulligan, Anna Marie, Nevanlinna, Heli, Nord, Silje, Olswold, Curtis, Osorio, Ana, Papi, Laura, Park-Simon, Tjoung-Won, Paulsson-Karlsson, Ylva, Peissel, Bernard, Peterlongo, Paolo, Pfeiler, Georg, Phelan, Catherine M, Radice, Paolo, Rashid, Muhammad Usman, Rennert, Gad, Salani, Ritu, Schmutzler, Rita K, Schoemaker, Minouk J, Shen, Chen-Yang, Shrubsole, Martha J, Shu, Xiao-Ou, Slager, Susan, Southey, Melissa, Szabo, Csilla I, Tchatchou, Sandrine, Teixeira, Manuel R, Tihomirova, Laima, Weitzel, Jeffrey N, Winqvist, Robert, Wong, Tien Y, Yu, Jyh-Cherng, Chenevix-Trench, Georgia, AOCS Investigators, Antoniou, Antonis C

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Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus von Long, Jirong, Bolla, Manjeet K, Wang, Qin, Dennis, Joe, Agata, Simona, Ahmed, Shahana, Aittomäki, Kristiina, Arason, Adalgeir, Arver, Brita, Beeghly-Fadiel, Alicia, Bermisheva, Marina, Blomqvist, Carl, Blot, William J, Bogdanova, Natalia V, Brauch, Hiltrud, Brennan, Paul, Broeks, Annegien, Cai, Qiuyin, Cox, Angela, Cross, Simon S, Daly, Mary B, de la Hoya, Miguel, Domchek, Susan M, Dorfling, Cecilia M, Dörk, Thilo, Dumont, Martine, Dworniczak, Bernd, Eilber, Ursula, Ejlertsen, Bent, Frost, Debra, Lalloo, Fiona, Fasching, Peter A, Flyger, Henrik, Friedlander, Michael, Friedman, Eitan, Garber, Judy, García-Closas, Montserrat, Gehrig, Andrea, Damiola, Francesca, Lesueur, Fabienne, Mazoyer, Sylvie, Goldgar, David E, González-Neira, Anna, Haiman, Christopher A, Hamann, Ute, Hansen, Thomas V. O, Hassan, Norhashimah, Hillemanns, Peter, Hollestelle, Antoinette, Ito, Hidemi, John, Esther M, Jones, Michael, Kauppila, Saila, Khan, Sofia, Le Marchand, Loic, Lester, Jenny, Liljegren, Annelie, Lindblom, Annika, Lubinski, Jan, Margolin, Sara, Matsuo, Keitaro, Muir, Kenneth, Nathanson, Katherine L, Neuhausen, Susan L, Nevanlinna, Heli, Newcomb, Polly A, Nussbaum, Robert L, Offit, Kenneth, Olah, Edith, Olopade, Olufunmilayo I, Park-Simon, Tjoung-Won, Peissel, Bernard, Peto, Julian, Rahman, Nazneen, Ramus, Susan J, Rudolph, Anja, Sangrajrang, Suleeporn, Schmidt, Marjanka K, Schmutzler, Rita K, Schürmann, Peter, Seynaeve, Caroline, Sigurdson, Alice, Singer, Christian F, Slager, Susan, Soucy, Penny, Southey, Melissa, Steinemann, Doris, Tchatchou, Sandrine, Teo, Soo H, Teulé, Alex, Toland, Amanda E, Tung, Nadine, van Rensburg, Elizabeth J, Vijai, Joseph, Wang-Gohrke, Shan, Whittemore, Alice S, Yannoukakos, Drakoulis, Pharoah, Paul D. P, Couch, Fergus J, Antoniou, Antonis C

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