Crystallographic Evidence for Preformed Dimers of Erythropoietin Receptor Before Ligand Activation von Livnah, Oded, Stura, Enrico A., Middleton, Steven A., Johnson, Dana L., Jolliffe, Linda K., Wilson, Ian A.

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Small Peptides as Potent Mimetics of the Protein Hormone Erythropoietin von Wrighton, Nicholas C., Farrell, Francis X., Chang, Ray, Kashyap, Arun K., Barbone, Francis P., Mulcahy, Linda S., Johnson, Dana L., Barrett, Ronald W., Jolliffe, Linda K., Dower, William J.

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Functional Mimicry of a Protein Hormone by a Peptide Agonist: The EPO Receptor Complex at 2.8 Å von Livnah, Oded, Stura, Enrico A., Johnson, Dana L., Middleton, Steven A., Mulcahy, Linda S., Wrighton, Nicholas C., Dower, William J., Jolliffe, Linda K., Wilson, Ian A.

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The in vitro and in vivo effects of JNJ-7706621 : A dual inhibitor of cyclin-dependent kinases and aurora kinases von EMANUEL, Stuart, RUGG, Catherine A, JOLLIFFE, Linda, MIDDLETON, Steven A, GRUNINGER, Robert H, RONGHUI LIN, FUENTES-PESQUERA, Angel, CONNOLLY, Peter J, WETTER, Steven K, HOLLISTER, Beth, KRUGER, Walter W, NAPIER, Cheryl

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Synthesis and Identification of [1,3,5]Triazine-pyridine Biheteroaryl as a Novel Series of Potent Cyclin-Dependent Kinase Inhibitors von Kuo, Gee-Hong, DeAngelis, Alan, Emanuel, Stuart, Wang, Aihua, Zhang, Yan, Connolly, Peter J, Chen, Xin, Gruninger, Robert H, Rugg, Catherine, Fuentes-Pesquera, Angel, Middleton, Steven A, Jolliffe, Linda, Murray, William V

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Increased potency of an erythropoietin peptide mimetic through covalent dimerization von Wrighton, Nicholas C, Balasubramanian, Palaniappan, Barbone, Francis P, Kashyap, Arun K, Farrell, Francis X, Jolliffe, Linda K, Barrett, Ronald W, Dower, William J

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Identification of a 13 Amino Acid Peptide Mimetic of Erythropoietin and Description of Amino Acids Critical for the Mimetic Activity of EMP1 von Johnson, Dana L, Farrell, Francis X, Barbone, Francis P, McMahon, Frank J, Tullai, Jennifer, Hoey, Kenway, Livnah, Oded, Wrighton, Nicholas C, Middleton, Steven A, Loughney, Deborah A, Stura, Enrico A, Dower, William J, Mulcahy, Linda S, Wilson, Ian A, Jolliffe, Linda K

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3-Acyl-2,6-diaminopyridines as cyclin-dependent kinase inhibitors: synthesis and biological evaluation von Lin, Ronghui, Lu, Yanhua, Wetter, Steven K., Connolly, Peter J., Turchi, Ignatius J., Murray, William V., Emanuel, Stuart L., Gruninger, Robert H., Fuentes-Pesquera, Angel R., Adams, Mary, Pandey, Niranjan, Moreno-Mazza, Sandra, Middleton, Steven A., Jolliffe, Linda K.

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Arylpiperazine substituted heterocycles as Selective α1a adrenergic antagonists von Khatuya, Haripada, Hutchings, Richard H, Kuo, Gee-Hong, Pulito, Virginia L, Jolliffe, Linda K, Li, Xiaobing, Murray, William V

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Erythropoietin induces changes in gene expression in PC-12 cells von Renzi, Michael J, Farrell, Francis X, Bittner, Anton, Galindo, Jose E, Morton, Mike, Trinh, Heather, Jolliffe, Linda K

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Novel thiophene derivatives for the treatment of benign prostatic hyperplasia von Khatuya, Haripada, Pulito, Virginia L., Jolliffe, Linda K., Li, Xiaobing, Murray, William V.

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Shared and Unique Determinants of the Erythropoietin (EPO) Receptor Are Important for Binding EPO and EPO Mimetic Peptide von Middleton, Steven A., Barbone, Francis P., Johnson, Dana L., Thurmond, Robin L., You, Yun, McMahon, Frank J., Jin, Renzhe, Livnah, Oded, Tullai, Jennifer, Farrell, Francis X., Goldsmith, Mark A., Wilson, Ian A., Jolliffe, Linda K.

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Phase I trial of a humanized, Fc receptor nonbinding OKT3 antibody, huOKT3γ1(Ala-Ala) in the treatment of acute renal allograft rejection von WOODLE, E. S, DANLIN XU, THISTLETHWAITE, J. R, ZIVIN, R. A, AUGER, J, CHARETTE, J, O'LAUGHLIN, R, PEACE, D, JOLLIFFE, L. K, HAVERTY, T, BLUESTONE, J. A

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Synthesis and Discovery of Macrocyclic Polyoxygenated Bis-7-azaindolylmaleimides as a Novel Series of Potent and Highly Selective Glycogen Synthase Kinase-3β Inhibitors von Kuo, Gee-Hong, Prouty, Catherine, DeAngelis, Alan, Shen, Lan, O'Neill, David J, Shah, Chandra, Connolly, Peter J, Murray, William V, Conway, Bruce R, Cheung, Peter, Westover, Lori, Xu, Jun Z, Look, Richard A, Demarest, Keith T, Emanuel, Stuart, Middleton, Steven A, Jolliffe, Linda, Beavers, Mary Pat, Chen, Xin

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Human recombinant erythropoietin significantly improves tumor oxygenation independent of its effects on hemoglobin von BLACKWELL, Kimberly L, KIRKPATRICK, John P, SNYDER, Stacey A, BROADWATER, Gloria, FARRELL, Francis, JOLLIFFE, Linda, BRIZEL, David M, DEWHIRST, Mark W

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Potential involvement of BMP receptor type IB activation in a synergistic effect of chondrogenic promotion between rhTGF beta 3 and rhGDF5 or rhBMP7 in human mesenchymal stem cells von Xu, Danlin, Gechtman, Ze'ev, Hughes, Anna, Collins, Alexander, Dodds, Robert, Cui, Xiaoling, Jolliffe, Linda, Higgins, Linda, Murphy, Alison, Farrell, Francis

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rHuEPO and Improved Treatment Outcomes: Potential Modes of Action von Blackwell, Kimberly, Gascón, Pere, Sigounas, George, Jolliffe, Linda

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Synthesis and Structure−Activity Relationships of Pyrazine-Pyridine Biheteroaryls as Novel, Potent, and Selective Vascular Endothelial Growth Factor Receptor-2 Inhibitors von Kuo, Gee-Hong, Prouty, Catherine, Wang, Aihua, Emanuel, Stuart, DeAngelis, Alan, Zhang, Yan, Song, Fengbin, Beall, Lawrence, Connolly, Peter J, Karnachi, Prahba, Chen, Xin, Gruninger, Robert H, Sechler, Jan, Fuentes-Pesquera, Angel, Middleton, Steven A, Jolliffe, Linda, Murray, William V

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Synthesis and Discovery of Pyrazine−Pyridine Biheteroaryl as a Novel Series of Potent Vascular Endothelial Growth Factor Receptor-2 Inhibitors von Kuo, Gee-Hong, Wang, Aihua, Emanuel, Stuart, DeAngelis, Alan, Zhang, Rui, Connolly, Peter J, Murray, William V, Gruninger, Robert H, Sechler, Jan, Fuentes-Pesquera, Angel, Johnson, Dana, Middleton, Steven A, Jolliffe, Linda, Chen, Xin

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PHASE I TRIAL OF A HUMANIZED, Fc RECEPTOR NONBINDING OKT3 ANTIBODY, huOKT3??1 (Ala-Ala) IN THE TREATMENT OF ACUTE RENAL ALLOGRAFT REJECTION von Woodle, E. Steve, Xu, Danlin, Zivin, Robert A., Auger, Julie, Charette, Jane, O'Laughlin, Rita, Peace, Donna, Jolliffe, Linda K., Haverty, Thomas, Bluestone, Jeffrey A., Thistlethwaite, J. Richard

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