Targeting the ERBB family in cancer: couples therapy von Tebbutt, Niall, Pedersen, Mikkel W., Johns, Terrance G.

Volltext

The epidermal growth factor receptor variant III (EGFRvIII): where wild things are altered von Gan, Hui K., Cvrljevic, Anna N., Johns, Terrance G.

Volltext

Lemming and Vole Cycles: A New Intrinsic Model von Levay, Elizabeth A., Nasser, Helen, Zelko, Matthew D., Penman, Jim, Johns, Terrance G.

Volltext

A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma von Stringer, Brett W., Day, Bryan W., D’Souza, Rochelle C. J., Jamieson, Paul R., Ensbey, Kathleen S., Bruce, Zara C., Lim, Yi Chieh, Goasdoué, Kate, Offenhäuser, Carolin, Akgül, Seçkin, Allan, Suzanne, Robertson, Thomas, Lucas, Peter, Tollesson, Gert, Campbell, Scott, Winter, Craig, Do, Hongdo, Dobrovic, Alexander, Inglis, Po-Ling, Jeffree, Rosalind L., Johns, Terrance G., Boyd, Andrew W.

Volltext

Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma von Inda, Maria-del-Mar, Bonavia, Rudy, Mukasa, Akitake, Narita, Yoshitaka, Sah, Dinah W Y, Vandenberg, Scott, Brennan, Cameron, Johns, Terrance G, Bachoo, Robert, Hadwiger, Philipp, Tan, Pamela, Depinho, Ronald A, Cavenee, Webster, Furnari, Frank

Volltext

ErbB4 in the brain: Focus on high grade glioma von Pitcher, Jamie-Lee, Alexander, Naomi, Miranda, Panimaya Jeffreena, Johns, Terrance G.

Volltext

Placental-Specific sFLT-1 e15a Protein Is Increased in Preeclampsia, Antagonizes Vascular Endothelial Growth Factor Signaling, and Has Antiangiogenic Activity von Palmer, Kirsten R, Kaitu'u-Lino, Tu'uhevaha J, Hastie, Roxanne, Hannan, Natalie J, Ye, Louie, Binder, Natalie, Cannon, Ping, Tuohey, Laura, Johns, Terrance G, Shub, Alexis, Tong, Stephen

Volltext

Anoctamins and Calcium Signalling: An Obstacle to EGFR Targeted Therapy in Glioblastoma? von Dewdney, Brittany, Ursich, Lauren, Fletcher, Emily V, Johns, Terrance G

Volltext

A Pre-Clinical Assessment of the Pan-ERBB Inhibitor Dacomitinib in Pediatric and Adult Brain Tumors von Endersby, Raelene, Whitehouse, Jacqueline, Hii, Hilary, Greenall, Sameer A., Johns, Terrance G., Gottardo, Nicholas G.

Volltext

Antibody-Functionalized Porous Silicon Nanoparticles for Vectorization of Hydrophobic Drugs von Secret, Emilie, Smith, Kevin, Dubljevic, Valentina, Moore, Eli, Macardle, Peter, Delalat, Bahman, Rogers, Mary-Louise, Johns, Terrance G., Durand, Jean-Olivier, Cunin, Frédérique, Voelcker, Nicolas H.

Volltext

Structural Optimization and Pharmacological Evaluation of Inhibitors Targeting Dual-Specificity Tyrosine Phosphorylation-Regulated Kinases (DYRK) and CDC-like kinases (CLK) in Glio... von Zhou, Qingqing, Phoa, Athena F, Abbassi, Ramzi H, Hoque, Monira, Reekie, Tristan A, Font, Josep S, Ryan, Renae M, Stringer, Brett W, Day, Bryan W, Johns, Terrance G, Munoz, Lenka, Kassiou, Michael

Volltext

Clinical Trials in the Brain Tumour Population: Challenges and Strategies for the Future von Gan, Hui Kong, Day, Bryan W., Harrup, Rosemary, Johns, Terrance G., Lwin, Zarnie, Scott, Andrew Mark, Sim, Hao-Wen, Koh, Eng-Siew

Volltext

Dual Targeting of the Epidermal Growth Factor Receptor Using the Combination of Cetuximab and Erlotinib: Preclinical Evaluation and Results of the Phase II DUX Study in Chemotherap... von WEICKHARDT, Andrew J, PRICE, Tim J, SALEMI, Renato, SCOTT, Andrew M, MARIADASON, John M, TEBBUTT, Niall C, CHONG, Geoff, GEBSKI, Val, PAVLAKIS, Nick, JOHNS, Terrance G, AZAD, Arun, SKRINOS, Effie, FLUCK, Kate, DOBROVIC, Alexander

Volltext

DYRK1A in neurodegeneration and cancer: Molecular basis and clinical implications von Abbassi, Ramzi, Johns, Terrance G, Kassiou, Michael, Munoz, Lenka

Volltext

From signalling pathways to targeted therapies: unravelling glioblastoma’s secrets and harnessing two decades of progress von Dewdney, Brittany, Jenkins, Misty R., Best, Sarah A., Freytag, Saskia, Prasad, Krishneel, Holst, Jeff, Endersby, Raelene, Johns, Terrance G.

Volltext

The dystroglycan receptor maintains glioma stem cells in the vascular niche von Day, Bryan W., Lathia, Justin D., Bruce, Zara C., D’Souza, Rochelle C. J., Baumgartner, Ulrich, Ensbey, Kathleen S., Lim, Yi Chieh, Stringer, Brett W., Akgül, Seçkin, Offenhäuser, Carolin, Li, Yuchen, Jamieson, Paul R., Smith, Fiona M., Jurd, Courtney L. R., Robertson, Thomas, Inglis, Po-Ling, Lwin, Zarnie, Jeffree, Rosalind L., Johns, Terrance G., Bhat, Krishna P. L., Rich, Jeremy N., Campbell, Kevin P., Boyd, Andrew W.

Volltext

Phosphorylation of dedicator of cytokinesis 1 (Dock180) at tyrosine residue Y722 by Src family kinases mediates EGFRvIII-driven glioblastoma tumorigenesis von Feng, Haizhong, Hu, Bo, Jarzynka, Michael J, Li, Yanxin, Keezer, Susan, Johns, Terrance G, Tang, Careen K, Hamilton, Ronald L, Vuori, Kristiina, Nishikawa, Ryo, Sarkaria, Jann N, Fenton, Tim, Cheng, Tao, Furnari, Frank B, Cavenee, Webster K, Cheng, Shi-Yuan

Volltext

Fyn and Src Are Effectors of Oncogenic Epidermal Growth Factor Receptor Signaling in Glioblastoma Patients von LU, Kan V, SHAOJUN ZHU, LEE, Yohan, ZUGEN CHEN, CALDWELL, Jeremy S, YONGMIN XIE, LOO, Joseph A, SELIGSON, David, CHAKRAVARI, Arnab, LEE, Francis Y, WEINMANN, Roberto, CLOUGHESY, Timothy F, CVRLJEVIC, Anna, NELSON, Stanley F, BERGERS, Gabriele, GRAEBER, Thomas, FURNARI, Frank B, JAMES, C. David, CAVENEE, Webster K, JOHNS, Terrance G, MISCHEL, Paul S, HUANG, Tiffany T, SARKARIA, Shawn, AHKAVAN, David, DANG, Julie, DINCA, Eduard B, PLAISIER, Seema B, ODERBERG, Isaac

Volltext

Global phosphoproteomics reveals DYRK1A regulates CDK1 activity in glioblastoma cells von Recasens, Ariadna, Humphrey, Sean J., Ellis, Michael, Hoque, Monira, Abbassi, Ramzi H., Chen, Brianna, Longworth, Mitchell, Needham, Elise J., James, David E., Johns, Terrance G., Day, Bryan W., Kassiou, Michael, Yang, Pengyi, Munoz, Lenka

Volltext

Incomplete target neutralization by the anti-cancer antibody rilotumumab von Greenall, Sameer A., Adams, Timothy E., Johns, Terrance G.

Volltext