Sphingosine-1-phosphate receptor 1 activation in astrocytes contributes to neuropathic pain von Chen, Zhoumou, Doyle, Timothy M., Luongo, Livio, Largent-Milnes, Tally M., Giancotti, Luigino Antonio, Kolar, Grant, Squillace, Silvia, Boccella, Serena, Walker, John K., Pendleton, Alexander, Spiegel, Sarah, Neumann, William L., Vanderah, Todd W., Salvemini, Daniela

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Structural basis of synthetic agonist activation of the nuclear receptor REV-ERB von Murray, Meghan H., Valfort, Aurore Cecile, Koelblen, Thomas, Ronin, Céline, Ciesielski, Fabrice, Chatterjee, Arindam, Veerakanellore, Giri Babu, Elgendy, Bahaa, Walker, John K., Hegazy, Lamees, Burris, Thomas P.

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Predictive Rules of Efflux Inhibition and Avoidance in Pseudomonas aeruginosa von Mehla, Jitender, Malloci, Giuliano, Mansbach, Rachael, Lopez, Cesar A., Tsivkovski, Ruslan, Haynes, Keith, Leus, Inga, Grindstaff, Sally B., Cascella, Robert H., D'Cunha, Napoleon, Herndon, Liam, Hengartner, Nicolas W., Margiotta, Enrico, Atzori, Alessio, Vargiu, Attilio V., Manrique, Pedro D., Walker, John K., Lomovskaya, Olga, Ruggerone, Paolo, Gnanakaran, S., Rybenkov, Valentin V., Zgurskaya, Helen

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A Repurposed Drug Screen Identifies Compounds That Inhibit the Binding of the COVID-19 Spike Protein to ACE2 von Tsegay, Kaleb B., Adeyemi, Christiana M., Gniffke, Edward P., Sather, D. Noah, Walker, John K., Smith, Stephen E. P.

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Predicting permeation of compounds across the outer membrane of P. aeruginosa using molecular descriptors von Manrique, Pedro D., Leus, Inga V., López, César A., Mehla, Jitender, Malloci, Giuliano, Gervasoni, Silvia, Vargiu, Attilio V., Kinthada, Rama K., Herndon, Liam, Hengartner, Nicolas W., Walker, John K., Rybenkov, Valentin V., Ruggerone, Paolo, Zgurskaya, Helen I., Gnanakaran, S.

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Multidrug Efflux Pumps and the Two-Faced Janus of Substrates and Inhibitors von Zgurskaya, Helen I, Walker, John K, Parks, Jerry M, Rybenkov, Valentin V

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Discovery of multidrug efflux pump inhibitors with a novel chemical scaffold von Green, Adam T., Moniruzzaman, Mohammad, Cooper, Connor J., Walker, John K., Smith, Jeremy C., Parks, Jerry M., Zgurskaya, Helen I.

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Structural Bioinformatics-Based Prediction of Exceptional Selectivity of p38 MAP Kinase Inhibitor PH-797804 von Xing, Li, Shieh, Huey S, Selness, Shaun R, Devraj, Rajesh V, Walker, John K, Devadas, Balekudru, Hope, Heidi R, Compton, Robert P, Schindler, John F, Hirsch, Jeffrey L, Benson, Alan G, Kurumbail, Ravi G, Stegeman, Roderick A, Williams, Jennifer M, Broadus, Richard M, Walden, Zara, Monahan, Joseph B

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Identification and structure–activity relationships for a series of N, N-disubstituted 2-aminobenzothiazoles as potent inhibitors of S. aureus von Cao, Feng, Kinthada, Ramakumar, Boehm, Terri, D' Cunha, Napoleon, Leus, Inga V., Orth, Cari, Zgurskaya, Helen I., Walker, John K.

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Inhibition of the C1s Protease and the Classical Complement Pathway by 6-(4-Phenylpiperazin-1-yl)Pyridine-3-Carboximidamide and Chemical Analogs von Xu, Xin, Herdendorf, Timothy J, Duan, Huiquan, Rohlik, Denise L, Roy, Sourav, Zhou, Hinman, Alkhateeb, Haya, Khandelwal, Sanjay, Zhou, Qilong, Li, Ping, Arepally, Gowthami M, Walker, John K, Garcia, Brandon L, Geisbrecht, Brian V

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Discovery and Characterization of Atropisomer PH-797804, a p38 MAP Kinase Inhibitor, as a Clinical Drug Candidate von Xing, Li, Devadas, Balekudru, Devraj, Rajesh V., Selness, Shaun R., Shieh, Huey, Walker, John K., Mao, Michael, Messing, Dean, Samas, Brian, Yang, Jerry Z., Anderson, Gary D., Webb, Elizabeth G., Monahan, Joseph B.

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Novel Pan-ERR Agonists Ameliorate Heart Failure Through Enhancing Cardiac Fatty Acid Metabolism and Mitochondrial Function von Xu, Weiyi, Billon, Cyrielle, Li, Hui, Wilderman, Andrea, Qi, Lei, Graves, Andrea, Rideb, Jernie Rae Dela Cruz, Zhao, Yuanbiao, Hayes, Matthew, Yu, Keyang, Losby, McKenna, Hampton, Carissa S, Adeyemi, Christiana M, Hong, Seok Jae, Nasiotis, Eleni, Fu, Chen, Oh, Tae Gyu, Fan, Weiwei, Downes, Michael, Welch, Ryan D, Evans, Ronald M, Milosavljevic, Aleksandar, Walker, John K, Jensen, Brian C, Pei, Liming, Burris, Thomas, Zhang, Lilei

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Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity von Billon, Cyrielle, Sitaula, Sadichha, Banerjee, Subhashis, Welch, Ryan, Elgendy, Bahaa, Hegazy, Lamees, Oh, Tae Gyu, Kazantzis, Melissa, Chatterjee, Arindam, Chrivia, John, Hayes, Matthew E., Xu, Weiyi, Hamilton, Angelica, Huss, Janice M., Zhang, Lilei, Walker, John K., Downes, Michael, Evans, Ronald M., Burris, Thomas P.

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GPR183-Oxysterol Axis in Spinal Cord Contributes to Neuropathic Pain von Braden, Kathryn, Giancotti, Luigino Antonio, Chen, Zhoumou, DeLeon, Chelsea, Latzo, Nick, Boehn, Terri, D'Cunha, Napoleon, Thompson, Bonne M., Doyle, Timothy M., McDonald, Jeffrey G., Walker, John K., Kolar, Grant R., Arnatt, Christopher Kent, Salvemini, Daniela

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Machine Learning Algorithm Identifies an Antibiotic Vocabulary for Permeating Gram-Negative Bacteria von Mansbach, Rachael A., Leus, Inga A., Mehla, Jitender, Lopez, Cesar A., Walker, John K., Rybenkov, Valentin V., Hengartner, Nicolas W., Zgurskaya, Helen, Gnanakaran, S.

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Identification and Structure–Activity Relationships of Novel Compounds that Potentiate the Activities of Antibiotics in Escherichia coli von Haynes, Keith M, Abdali, Narges, Jhawar, Varsha, Zgurskaya, Helen I, Parks, Jerry M, Green, Adam T, Baudry, Jerome, Rybenkov, Valentin V, Smith, Jeremy C, Walker, John K

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Development and pharmacological evaluation of a new chemical series of potent pan-ERR agonists, identification of SLU-PP-915 von Hampton, Carissa S., Sitaula, Sadichha, Billon, Cyrielle, Haynes, Keith, Avdagic, Amer, Wanninayake, Udayanga, Adeyemi, Christiana M., Chatterjee, Arindam, Griffett, Kristine, Banerjee, Subhashis, Burris, Sheryl L., Schoepke, Emmalie, Boehm, Terri, Bess, Alex, de Vera, Ian Mitchelle S., Burris, Thomas P., Walker, John K.

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Estrogen-Related Receptor Agonism Reverses Mitochondrial Dysfunction and Inflammation in the Aging Kidney von Wang, Xiaoxin X, Myakala, Komuraiah, Libby, Andrew E, Krawczyk, Ewa, Panov, Julia, Jones, Bryce A, Bhasin, Kanchan, Shults, Nataliia, Qi, Yue, Krausz, Kristopher W, Zerfas, Patricia M, Takahashi, Shogo, Daneshpajouhnejad, Parnaz, Titievsky, Avi, Taranenko, Elizaveta, Billon, Cyrielle, Chatterjee, Arindam, Elgendy, Bahaa, Walker, John K, Albanese, Chris, Kopp, Jeffrey B, Rosenberg, Avi Z, Gonzalez, Frank J, Guha, Udayan, Brodsky, Leonid, Burris, Thomas P, Levi, Moshe

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A Selective ERRα/γ Inverse Agonist, SLU-PP-1072, Inhibits the Warburg Effect and Induces Apoptosis in Prostate Cancer Cells von Schoepke, Emmalie, Billon, Cyrielle, Haynes, Keith M, Avdagic, Amer, Sitaula, Sadichha, Sanders, Ryan, Adeyemi, Christiana M, Walker, John K, Burris, Thomas P

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International Union of Basic and Clinical Pharmacology CXIII: Nuclear Receptor Superfamily-Update 2023 von Burris, Thomas P, de Vera, Ian Mitchelle S, Cote, Isabelle, Flaveny, Colin A, Wanninayake, Udayanga S, Chatterjee, Arindam, Walker, John K, Steinauer, Nickolas, Zhang, Jinsong, Coons, Laurel A, Korach, Kenneth S, Cain, Derek W, Hollenberg, Anthony N, Webb, Paul, Forrest, Douglas, Jetten, Anton M, Edwards, Dean P, Grimm, Sandra L, Hartig, Sean, Lange, Carol A, Richer, Jennifer K, Sartorius, Carol A, Tetel, Marc, Billon, Cyrielle, Elgendy, Bahaa, Hegazy, Lamees, Griffett, Kristine, Peinetti, Nahuel, Burnstein, Kerry L, Hughes, Travis S, Sitaula, Sadichha, Stayrook, Keitch R, Culver, Alexander, Murray, Meghan H, Finck, Brian N, Cidlowski, John A

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