Mechanisms of Jak/STAT signaling in immunity and disease von Villarino, Alejandro V, Kanno, Yuka, Ferdinand, John R, O'Shea, John J

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Macrophage metabolic reprogramming presents a therapeutic target in lupus nephritis von Jing, Chenzhi, Castro-Dopico, Tomas, Richoz, Nathan, Tuong, Zewen K., Ferdinand, John R., Lok, Laurence S. C., Loudon, Kevin W., Banham, Gemma D., Mathews, Rebeccah J., Cader, Zaeem, Fitzpatrick, Susan, Bashant, Kathleen R., Kaplan, Mariana J., Kaser, Arthur, Johnson, Randall S., Murphy, Michael P., Siegel, Richard M., Clatworthy, Menna R.

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A cell atlas of human thymic development defines T cell repertoire formation von Park, Jong-Eun, Botting, Rachel A, Domínguez Conde, Cecilia, Popescu, Dorin-Mirel, Lavaert, Marieke, Kunz, Daniel J, Goh, Issac, Stephenson, Emily, Ragazzini, Roberta, Tuck, Elizabeth, Wilbrey-Clark, Anna, Roberts, Kenny, Kedlian, Veronika R, Ferdinand, John R, He, Xiaoling, Webb, Simone, Maunder, Daniel, Vandamme, Niels, Mahbubani, Krishnaa T, Polanski, Krzysztof, Mamanova, Lira, Bolt, Liam, Crossland, David, de Rita, Fabrizio, Fuller, Andrew, Filby, Andrew, Reynolds, Gary, Dixon, David, Saeb-Parsy, Kourosh, Lisgo, Steven, Henderson, Deborah, Vento-Tormo, Roser, Bayraktar, Omer A, Barker, Roger A, Meyer, Kerstin B, Saeys, Yvan, Bonfanti, Paola, Behjati, Sam, Clatworthy, Menna R, Taghon, Tom, Haniffa, Muzlifah, Teichmann, Sarah A

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GM-CSF Calibrates Macrophage Defense and Wound Healing Programs during Intestinal Infection and Inflammation von Castro-Dopico, Tomas, Fleming, Aaron, Dennison, Thomas W., Ferdinand, John R., Harcourt, Katherine, Stewart, Benjamin J., Cader, Zaeem, Tuong, Zewen K., Jing, Chenzhi, Lok, Laurence S.C., Mathews, Rebeccah J., Portet, Anaïs, Kaser, Arthur, Clare, Simon, Clatworthy, Menna R.

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Gut-educated IgA plasma cells defend the meningeal venous sinuses von Fitzpatrick, Zachary, Frazer, Gordon, Ferro, Ashley, Clare, Simon, Bouladoux, Nicolas, Ferdinand, John, Tuong, Zewen Kelvin, Negro-Demontel, Maria Luciana, Kumar, Nitin, Suchanek, Ondrej, Tajsic, Tamara, Harcourt, Katherine, Scott, Kirsten, Bashford-Rogers, Rachel, Helmy, Adel, Reich, Daniel S., Belkaid, Yasmine, Lawley, Trevor D., McGavern, Dorian B., Clatworthy, Menna R.

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Regional Differences in Human Biliary Tissues and Corresponding In Vitro–Derived Organoids von Rimland, Casey A., Tilson, Samantha G., Morell, Carola M., Tomaz, Rute A., Lu, Wei‐Yu, Adams, Simone E., Georgakopoulos, Nikitas, Otaizo‐Carrasquero, Francisco, Myers, Timothy G., Ferdinand, John R., Gieseck, Richard L., Sampaziotis, Fotios, Tysoe, Olivia C., Ross, Alexander, Kraiczy, Judith M., Wesley, Brandon, Muraro, Daniele, Zilbauer, Matthias, Oniscu, Gabriel C., Hannan, Nicholas R.F., Forbes, Stuart J., Saeb‐Parsy, Kourosh, Wynn, Thomas A., Vallier, Ludovic

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Aldehyde-driven transcriptional stress triggers an anorexic DNA damage response von Mulderrig, Lee, Garaycoechea, Juan I., Tuong, Zewen K., Millington, Christopher L., Dingler, Felix A., Ferdinand, John R., Gaul, Liam, Tadross, John A., Arends, Mark J., O’Rahilly, Stephen, Crossan, Gerry P., Clatworthy, Menna R., Patel, Ketan J.

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Spatiotemporal immune zonation of the human kidney von Stewart, Benjamin J, Ferdinand, John R, Young, Matthew D, Mitchell, Thomas J, Loudon, Kevin W, Riding, Alexandra M, Richoz, Nathan, Frazer, Gordon L, Staniforth, Joy U L, Vieira Braga, Felipe A, Botting, Rachel A, Popescu, Dorin-Mirel, Vento-Tormo, Roser, Stephenson, Emily, Cagan, Alex, Farndon, Sarah J, Polanski, Krzysztof, Efremova, Mirjana, Green, Kile, Del Castillo Velasco-Herrera, Martin, Guzzo, Charlotte, Collord, Grace, Mamanova, Lira, Aho, Tevita, Armitage, James N, Riddick, Antony C P, Mushtaq, Imran, Farrell, Stephen, Rampling, Dyanne, Nicholson, James, Filby, Andrew, Burge, Johanna, Lisgo, Steven, Lindsay, Susan, Bajenoff, Marc, Warren, Anne Y, Stewart, Grant D, Sebire, Neil, Coleman, Nicholas, Haniffa, Muzlifah, Teichmann, Sarah A, Behjati, Sam, Clatworthy, Menna R

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Using single-cell technologies to map the human immune system — implications for nephrology von Stewart, Benjamin J., Ferdinand, John R., Clatworthy, Menna R.

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Anti-commensal IgG Drives Intestinal Inflammation and Type 17 Immunity in Ulcerative Colitis von Castro-Dopico, Tomas, Dennison, Thomas W., Ferdinand, John R., Mathews, Rebeccah J., Fleming, Aaron, Clift, Dean, Stewart, Benjamin J., Jing, Chenzhi, Strongili, Konstantina, Labzin, Larisa I., Monk, Edward J.M., Saeb-Parsy, Kourosh, Bryant, Clare E., Clare, Simon, Parkes, Miles, Clatworthy, Menna R.

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Distinct microbial and immune niches of the human colon von James, Kylie R., Gomes, Tomas, Elmentaite, Rasa, Kumar, Nitin, Gulliver, Emily L., King, Hamish W., Stares, Mark D., Bareham, Bethany R., Ferdinand, John R., Petrova, Velislava N., Polański, Krzysztof, Forster, Samuel C., Jarvis, Lorna B., Suchanek, Ondrej, Howlett, Sarah, James, Louisa K., Jones, Joanne L., Meyer, Kerstin B., Clatworthy, Menna R., Saeb-Parsy, Kourosh, Lawley, Trevor D., Teichmann, Sarah A.

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Renal Sodium Gradient Orchestrates a Dynamic Antibacterial Defense Zone von Berry, Miriam R., Mathews, Rebeccah J., Ferdinand, John R., Jing, Chenzhi, Loudon, Kevin W., Wlodek, Elizabeth, Dennison, Thomas W., Kuper, Christoph, Neuhofer, Wolfgang, Clatworthy, Menna R.

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Tissue-resident B cells orchestrate macrophage polarisation and function von Suchanek, Ondrej, Ferdinand, John R., Tuong, Zewen K., Wijeyesinghe, Sathi, Chandra, Anita, Clauder, Ann-Katrin, Almeida, Larissa N., Clare, Simon, Harcourt, Katherine, Ward, Christopher J., Bashford-Rogers, Rachael, Lawley, Trevor, Manz, Rudolf A., Okkenhaug, Klaus, Masopust, David, Clatworthy, Menna R.

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In vivo labeling reveals continuous trafficking of TCF-1+ T cells between tumor and lymphoid tissue von Li, Zhi, Tuong, Zewen K, Dean, Isaac, Willis, Claire, Gaspal, Fabrina, Fiancette, Rémi, Idris, Suaad, Kennedy, Bethany, Ferdinand, John R, Peñalver, Ana, Cabantous, Mia, Murtuza Baker, Syed, Fry, Jeremy W, Carlesso, Gianluca, Hammond, Scott A, Dovedi, Simon J, Hepworth, Matthew R, Clatworthy, Menna R, Withers, David R

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Mapping single-cell transcriptomes in the intra-tumoral and associated territories of kidney cancer von Li, Ruoyan, Ferdinand, John R., Loudon, Kevin W., Bowyer, Georgina S., Laidlaw, Sean, Muyas, Francesc, Mamanova, Lira, Neves, Joana B., Bolt, Liam, Fasouli, Eirini S., Lawson, Andrew R.J., Young, Matthew D., Hooks, Yvette, Oliver, Thomas R.W., Butler, Timothy M., Armitage, James N., Aho, Tev, Riddick, Antony C.P., Gnanapragasam, Vincent, Welsh, Sarah J., Meyer, Kerstin B., Warren, Anne Y., Tran, Maxine G.B., Stewart, Grant D., Cortés-Ciriano, Isidro, Behjati, Sam, Clatworthy, Menna R., Campbell, Peter J., Teichmann, Sarah A., Mitchell, Thomas J.

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Recycling of memory B cells between germinal center and lymph node subcapsular sinus supports affinity maturation to antigenic drift von Zhang, Yang, Garcia-Ibanez, Laura, Ulbricht, Carolin, Lok, Laurence S. C., Pike, Jeremy A., Mueller-Winkler, Jennifer, Dennison, Thomas W., Ferdinand, John R., Burnett, Cameron J. M., Yam-Puc, Juan C., Zhang, Lingling, Alfaro, Raul Maqueda, Takahama, Yousuke, Ohigashi, Izumi, Brown, Geoffrey, Kurosaki, Tomohiro, Tybulewicz, Victor L. J., Rot, Antal, Hauser, Anja E., Clatworthy, Menna R., Toellner, Kai-Michael

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Cytokine absorption during human kidney perfusion reduces delayed graft function–associated inflammatory gene signature von Ferdinand, John R., Hosgood, Sarah A., Moore, Tom, Ferro, Ashley, Ward, Christopher J., Castro‐Dopico, Tomas, Nicholson, Michael L., Clatworthy, Menna R.

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Selective Disruption of Mitochondrial Thiol Redox State in Cells and In Vivo von Booty, Lee M., Gawel, Justyna M., Cvetko, Filip, Caldwell, Stuart T., Hall, Andrew R., Mulvey, John F., James, Andrew M., Hinchy, Elizabeth C., Prime, Tracy A., Arndt, Sabine, Beninca, Cristiane, Bright, Thomas P., Clatworthy, Menna R., Ferdinand, John R., Prag, Hiran A., Logan, Angela, Prudent, Julien, Krieg, Thomas, Hartley, Richard C., Murphy, Michael P.

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HIF1A and NFAT5 coordinate Na+-boosted antibacterial defense via enhanced autophagy and autolysosomal targeting von Neubert, Patrick, Weichselbaum, Andrea, Reitinger, Carmen, Schatz, Valentin, Schröder, Agnes, Ferdinand, John R., Simon, Michaela, Bär, Anna-Lorena, Brochhausen, Christoph, Gerlach, Roman G., Tomiuk, Stefan, Hammer, Karin, Wagner, Stefan, van Zandbergen, Ger, Binger, Katrina J., Müller, Dominik N., Kitada, Kento, Clatworthy, Menna R., Kurts, Christian, Titze, Jens, Abdullah, Zeinab, Jantsch, Jonathan

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Lysis of cold‐storage‐induced microvascular obstructions for ex vivo revitalization of marginal human kidneys von DiRito, Jenna R., Hosgood, Sarah A., Reschke, Melanie, Albert, Claire, Bracaglia, Laura G., Ferdinand, John R., Stewart, Benjamin J., Edwards, Christopher M., Vaish, Anand G., Thiru, Sathia, Mulligan, David C., Haakinson, Danielle J., Clatworthy, Menna R., Saltzman, W. Mark, Pober, Jordan S., Nicholson, Michael L., Tietjen, Gregory T.

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