The NDV-3A vaccine protects mice from multidrug resistant Candida auris infection von Singh, Shakti, Uppuluri, Priya, Mamouei, Zeinab, Alqarihi, Abdullah, Elhassan, Hana, French, Samuel, Lockhart, Shawn R, Chiller, Tom, Edwards, Jr, John E, Ibrahim, Ashraf S

Volltext

Th1-Th17 cells mediate protective adaptive immunity against Staphylococcus aureus and Candida albicans infection in mice von Lin, Lin, Ibrahim, Ashraf S, Xu, Xin, Farber, Joshua M, Avanesian, Valentina, Baquir, Beverlie, Fu, Yue, French, Samuel W, Edwards, Jr, John E, Spellberg, Brad

Volltext

GRP78 and Integrins Play Different Roles in Host Cell Invasion during Mucormycosis von Alqarihi, Abdullah, Gebremariam, Teclegiorgis, Gu, Yiyou, Swidergall, Marc, Alkhazraji, Sondus, Soliman, Sameh S. M., Bruno, Vincent M., Edwards, John E. Jr Jr, Filler, Scott G., Uppuluri, Priya, Ibrahim, Ashraf S.

Volltext

NDV-3, a recombinant alum-adjuvanted vaccine for Candida and Staphylococcus aureus , is safe and immunogenic in healthy adults von Schmidt, Clint S, White, C. Jo, Ibrahim, Ashraf S, Filler, Scott G, Fu, Yue, Yeaman, Michael R, Edwards Jr., John E, Hennessey Jr., John P

Volltext

Als3 is a Candida albicans invasin that binds to cadherins and induces endocytosis by host cells von Phan, Quynh T, Myers, Carter L, Fu, Yue, Sheppard, Donald C, Yeaman, Michael R, Welch, William H, Ibrahim, Ashraf S, Edwards, Jr, John E, Filler, Scott G

Volltext

Bicarbonate correction of ketoacidosis alters host-pathogen interactions and alleviates mucormycosis von Gebremariam, Teclegiorgis, Lin, Lin, Liu, Mingfu, Kontoyiannis, Dimitrios P, French, Samuel, Edwards, Jr, John E, Filler, Scott G, Ibrahim, Ashraf S

Volltext

PCR-Based Approach Targeting Mucorales-Specific Gene Family for Diagnosis of Mucormycosis von Baldin, Clara, Soliman, Sameh S M, Jeon, Heewon H, Alkhazraji, Sondus, Gebremariam, Teclegiorgis, Gu, Yiyou, Bruno, Vincent M, Cornely, Oliver A, Leather, Helen L, Sugrue, Michele W, Wingard, John R, Stevens, David A, Edwards, Jr, John E, Ibrahim, Ashraf S

Volltext

Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America von Boucher, Helen W., Talbot, George H., Bradley, John S., Edwards, John E., Gilbert, David, Rice, Louis B., Scheld, Michael, Spellberg, Brad, Bartlett, John

Volltext

high affinity iron permease is a key virulence factor required for Rhizopus oryzae pathogenesis von Ibrahim, Ashraf S, Gebremariam, Teclegiorgis, Lin, Lin, Luo, Guanpingsheng, Husseiny, Mohamed I, Skory, Christopher D, Fu, Yue, French, Samuel W, Edwards, John E. Jr, Spellberg, Brad

Volltext

CotH3 mediates fungal invasion of host cells during mucormycosis von Gebremariam, Teclegiorgis, Liu, Mingfu, Luo, Guanpingsheng, Bruno, Vincent, Phan, Quynh T, Waring, Alan J, Edwards, Jr, John E, Filler, Scott G, Yeaman, Michael R, Ibrahim, Ashraf S

Volltext

The endothelial cell receptor GRP78 is required for mucormycosis pathogenesis in diabetic mice von Liu, Mingfu, Spellberg, Brad, Phan, Quynh T, Fu, Yue, Fu, Yong, Lee, Amy S, Edwards, Jr, John E, Filler, Scott G, Ibrahim, Ashraf S

Volltext

Clinical Practice Guidelines for the Management Candidiasis: 2009 Update by the Infectious Diseases Society of America von Pappas, Peter G., Kauffman, Carol A., Andes, David, Benjamin, Daniel K., Calandra, Thierry F., Edwards, John E., Filler, Scott G., Fisher, John F., Kullberg, Bart-Jan, Zeichner, Luis Ostrosky, Reboli, Annette C., Rex, John H., Walsh, Thomas J., Sobe, Jack D.

Volltext

Fob1 and Fob2 Proteins Are Virulence Determinants of Rhizopus oryzae via Facilitating Iron Uptake from Ferrioxamine von Liu, Mingfu, Lin, Lin, Gebremariam, Teclegiorgis, Luo, Guanpingsheng, Skory, Christopher D, French, Samuel W, Chou, Tsui-Fen, Edwards, Jr, John E, Ibrahim, Ashraf S

Volltext

An oxindole efflux inhibitor potentiates azoles and impairs virulence in the fungal pathogen Candida auris von Iyer, Kali R., Camara, Kaddy, Daniel-Ivad, Martin, Trilles, Richard, Pimentel-Elardo, Sheila M., Fossen, Jen L., Marchillo, Karen, Liu, Zhongle, Singh, Shakti, Muñoz, José F., Kim, Sang Hu, Porco, John A., Cuomo, Christina A., Williams, Noelle S., Ibrahim, Ashraf S., Edwards, John E., Andes, David R., Nodwell, Justin R., Brown, Lauren E., Whitesell, Luke, Robbins, Nicole, Cowen, Leah E.

Volltext

Trends in Antimicrobial Drug Development: Implications for the Future von Spellberg, Brad, Powers, John H., Brass, Eric P., Miller, Loren G., Edwards, John E.

Volltext

Critical role of Bcr1-dependent adhesins in C. albicans biofilm formation in vitro and in vivo von Nobile, Clarissa J, Andes, David R, Nett, Jeniel E, Smith, Frank J, Yue, Fu, Phan, Quynh-Trang, Edwards, John E, Filler, Scott G, Mitchell, Aaron P

Volltext

The iron chelator deferasirox protects mice from mucormycosis through iron starvation von Ibrahim, Ashraf S, Gebermariam, Teclegiorgis, Fu, Yue, Lin, Lin, Husseiny, Mohamed I, French, Samuel W, Schwartz, Julie, Skory, Christopher D, Edwards, Jr, John E, Spellberg, Brad J

Volltext

the hyphal-associated adhesin and invasin Als3 of Candida albicans mediates iron acquisition from host ferritin von Almeida, Ricardo S, Brunke, Sascha, Albrecht, Antje, Thewes, Sascha, Laue, Michael, Edwards, John E, Filler, Scott G, Hube, Bernhard

Volltext

A Fungal Immunotherapeutic Vaccine (NDV-3A) for Treatment of Recurrent Vulvovaginal Candidiasis-A Phase 2 Randomized, Double-Blind, Placebo-Controlled Trial von Edwards, Jr, John E, Schwartz, Michael M, Schmidt, Clint S, Sobel, Jack D, Nyirjesy, Paul, Schodel, Florian, Marchus, Erica, Lizakowski, Mary, DeMontigny, Elizabeth A, Hoeg, Jesse, Holmberg, Tuomas, Cooke, M Timothy, Hoover, Keila, Edwards, Lance, Jacobs, Mark, Sussman, Steven, Augenbraun, Michael, Drusano, Michael, Yeaman, Michael R, Ibrahim, Ashraf S, Filler, Scott G, Hennessey, Jr, John P

Volltext

Antifungal Vaccine Derived from the Recombinant N Terminus of Als3p Protects Mice against the Bacterium Staphylococcus aureus von Spellberg, Brad, Ibrahim, Ashraf S, Yeaman, Michael R, Lin, Lin, Fu, Yue, Avanesian, Valentina, Bayer, Arnold S, Filler, Scott G, Lipke, Peter, Otoo, Henry, Edwards, John E. Jr

Volltext