Extracellular vesicles as drug delivery systems: Why and how? von Elsharkasy, Omnia M., Nordin, Joel Z., Hagey, Daniel W., de Jong, Olivier G., Schiffelers, Raymond M., Andaloussi, Samir EL, Vader, Pieter

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Identification of scaffold proteins for improved endogenous engineering of extracellular vesicles von Zheng, Wenyi, Rädler, Julia, Sork, Helena, Niu, Zheyu, Roudi, Samantha, Bost, Jeremy P., Görgens, André, Zhao, Ying, Mamand, Doste R., Liang, Xiuming, Wiklander, Oscar P. B., Lehto, Taavi, Gupta, Dhanu, Nordin, Joel Z., EL Andaloussi, Samir

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Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties von Nordin, Joel Z., M.D, Lee, Yi, BSc, Vader, Pieter, PhD, Mäger, Imre, PhD, Johansson, Henrik J., PhD, Heusermann, Wolf, PhD, Wiklander, Oscar P.B., M.D, Hällbrink, Mattias, PhD, Seow, Yiqi, DPhil, Bultema, Jarred J., PhD, Gilthorpe, Jonathan, PhD, Davies, Tim, MSc, Fairchild, Paul J., PhD, Gabrielsson, Susanne, PhD, Meisner-Kober, Nicole C., PhD, Lehtiö, Janne, PhD, Smith, C.I. Edvard, M.D., PhD, Wood, Matthew J.A., M.D., DPhil, Andaloussi, Samir EL, PhD

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Reproducible and scalable purification of extracellular vesicles using combined bind-elute and size exclusion chromatography von Corso, Giulia, Mäger, Imre, Lee, Yi, Görgens, André, Bultema, Jarred, Giebel, Bernd, Wood, Matthew J. A., Nordin, Joel Z., Andaloussi, Samir EL

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Heterogeneity and interplay of the extracellular vesicle small RNA transcriptome and proteome von Sork, Helena, Corso, Giulia, Krjutskov, Kaarel, Johansson, Henrik J., Nordin, Joel Z., Wiklander, Oscar P. B., Lee, Yi Xin Fiona, Westholm, Jakub Orzechowski, Lehtiö, Janne, Wood, Matthew J. A., Mäger, Imre, EL Andaloussi, Samir

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Autoimmune response and its long‐term consequences after exon‐skipping therapy in a Duchenne muscular dystrophy mouse model von Nordin, Joel Z, Aoki, Yoshitsugu

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Systemic exosomal siRNA delivery reduced alpha‐synuclein aggregates in brains of transgenic mice von Cooper, J. Mark, Wiklander, P.B. Oscar, Nordin, Joel Z., Al‐Shawi, Raya, Wood, Matthew J., Vithlani, Mansi, Schapira, Anthony H. V., Simons, J. Paul, El‐Andaloussi, Samir, Alvarez‐Erviti, Lydia

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Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting von Wiklander, Oscar P. B., Nordin, Joel Z., O'Loughlin, Aisling, Gustafsson, Ylva, Corso, Giulia, Mäger, Imre, Vader, Pieter, Lee, Yi, Sork, Helena, Seow, Yiqi, Heldring, Nina, Alvarez-Erviti, Lydia, Smith, CI Edvard, Le Blanc, Katarina, Macchiarini, Paolo, Jungebluth, Philipp, Wood, Matthew J. A., Andaloussi, Samir EL

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Systematic Methodological Evaluation of a Multiplex Bead-Based Flow Cytometry Assay for Detection of Extracellular Vesicle Surface Signatures von Wiklander, Oscar P B, Bostancioglu, R Beklem, Welsh, Joshua A, Zickler, Antje M, Murke, Florian, Corso, Giulia, Felldin, Ulrika, Hagey, Daniel W, Evertsson, Björn, Liang, Xiu-Ming, Gustafsson, Manuela O, Mohammad, Dara K, Wiek, Constanze, Hanenberg, Helmut, Bremer, Michel, Gupta, Dhanu, Björnstedt, Mikael, Giebel, Bernd, Nordin, Joel Z, Jones, Jennifer C, El Andaloussi, Samir, Görgens, André

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Transfection reagents affect Extracellular Vesicle cargo transfer to recipient cells: The importance of appropriate controls in EV research von Nordin, Joel Z.

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Quantification of extracellular vesicles in vitro and in vivo using sensitive bioluminescence imaging von Gupta, Dhanu, Liang, Xiuming, Pavlova, Svetlana, Wiklander, Oscar P.B, Corso, Giulia, Zhao, Ying, Saher, Osama, Bost, Jeremy, Zickler, Antje M., Piffko, Andras, Maire, Cecile L., Ricklefs, Franz L., Gustafsson, Oskar, Llorente, Virginia Castilla, Gustafsson, Manuela O., Bostancioglu, R. Beklem, Mamand, Doste R, Hagey, Daniel W., Görgens, André, Nordin, Joel Z., EL Andaloussi, Samir

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Extracellular vesicles transport RNA between cells: Unraveling their dual role in diagnostics and therapeutics von Payandeh, Zahra, Tangruksa, Benyapa, Synnergren, Jane, Heydarkhan-Hagvall, Sepideh, Nordin, Joel Z., Andaloussi, Samir EL, Borén, Jan, Wiseman, John, Bohlooly-Y, Mohammad, Lindfors, Lennart, Valadi, Hadi

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Engineered extracellular vesicle decoy receptor-mediated modulation of the IL6 trans-signalling pathway in muscle von Conceição, Mariana, Forcina, Laura, Wiklander, Oscar P.B., Gupta, Dhanu, Nordin, Joel Z., Vrellaku, Besarte, McClorey, Graham, Mäger, Imre, Gӧrgens, André, Lundin, Per, Musarò, Antonio, Wood, Matthew J.A., Andaloussi, Samir EL, Roberts, Thomas C.

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Extracellular vesicles as the next‐generation modulators of pharmacokinetics and pharmacodynamics of medications and their potential as adjuvant therapeutics von Liu, Jiaqi, Nordin, Joel Z., McLachlan, Andrew J., Chrzanowski, Wojciech

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Systemic exosomal siRNA delivery reduced alpha-synuclein aggregates in brains of transgenic mice von Cooper, J. Mark, Wiklander, P.B. Oscar, Nordin, Joel Z., Al-Shawi, Raya, Wood, Matthew J., Vithlani, Mansi, Schapira, Anthony H. V., Simons, J. Paul, El-Andaloussi, Samir, Alvarez-Erviti, Lydia

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Efficient Peptide-Mediated In Vitro Delivery of Cas9 RNP von Gustafsson, Oskar, Rädler, Julia, Roudi, Samantha, Lehto, Tõnis, Hällbrink, Mattias, Lehto, Taavi, Gupta, Dhanu, Andaloussi, Samir EL, Nordin, Joel Z.

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Extracellular vesicles engineered to bind albumin demonstrate extended circulation time and lymph node accumulation in mouse models von Liang, Xiuming, Niu, Zheyu, Galli, Valentina, Howe, Nathalie, Zhao, Ying, Wiklander, Oscar P. B., Zheng, Wenyi, Wiklander, Rim Jawad, Corso, Giulia, Davies, Christopher, Hean, Justin, Kyriakopoulou, Eleni, Mamand, Doste R., Amin, Risul, Nordin, Joel Z., Gupta, Dhanu, Andaloussi, Samir EL

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Tangential Flow Filtration with or Without Subsequent Bind-Elute Size Exclusion Chromatography for Purification of Extracellular Vesicles von Nordin, Joel Z., Bostancioglu, R. Beklem, Corso, Giulia, EL Andaloussi, Samir

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Exosome-like vesicles released from lipid-induced insulin-resistant muscles modulate gene expression and proliferation of beta recipient cells in mice von Jalabert, Audrey, Vial, Guillaume, Guay, Claudiane, Wiklander, Oscar P. B., Nordin, Joel Z., Aswad, Hala, Forterre, Alexis, Meugnier, Emmanuelle, Pesenti, Sandra, Regazzi, Romano, Danty-Berger, Emmanuelle, Ducreux, Sylvie, Vidal, Hubert, El-Andaloussi, Samir, Rieusset, Jennifer, Rome, Sophie

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Lipidomic Analyses Reveal Specific Alterations of Phosphatidylcholine in Dystrophic Mdx Muscle von Valentine, William J, Mostafa, Sherif A, Tokuoka, Suzumi M, Hamano, Fumie, Inagaki, Natsuko F, Nordin, Joel Z, Motohashi, Norio, Kita, Yoshihiro, Aoki, Yoshitsugu, Shimizu, Takao, Shindou, Hideo

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