CYP induction-mediated drug interactions: in vitro assessment and clinical implications von Lin, Jiunn H

Volltext

Drug–drug interaction mediated by inhibition and induction of P-glycoprotein von Lin, Jiunn H

Volltext

Clinical Relevance of P-Glycoprotein in Drug Therapy von Lin, Jiunn H., Yamazaki, Masayo

Volltext

An in-vitro cocktail assay for assessing compound-mediated inhibition of six major cytochrome P450 enzymes von Wang, Jing-Jing, Guo, Jian-Jun, Zhan, Jenny, Bu, Hai-Zhi, Lin, Jiunn H.

Volltext

Complicating factors in safety testing of drug metabolites: Kinetic differences between generated and preformed metabolites von Prueksaritanont, Thomayant, Lin, Jiunn H., Baillie, Thomas A.

Volltext

Preclinical validation of a potent γ-secretase modulator for Alzheimer's disease prevention von Rynearson, Kevin D, Ponnusamy, Moorthi, Prikhodko, Olga, Xie, Yuhuan, Zhang, Can, Nguyen, Phuong, Hug, Brenda, Sawa, Mariko, Becker, Ann, Spencer, Brian, Florio, Jazmin, Mante, Michael, Salehi, Bahar, Arias, Carlos, Galasko, Douglas, Head, Brian P, Johnson, Graham, Lin, Jiunn H, Duddy, Steven K, Rissman, Robert A, Mobley, William C, Thinakaran, Gopal, Tanzi, Rudolph E, Wagner, Steven L

Volltext

Role of P-glycoprotein in pharmacokinetics: Clinical implications von LIN, Jiunn H, YAMAZAKI, Masayo

Volltext

Transporter-mediated drug interactions: clinical implications and in vitro assessment von Lin, Jiunn H

Volltext

Pharmacological and Toxicological Properties of the Potent Oral γ -Secretase Modulator BPN-15606 von Wagner, Steven L, Rynearson, Kevin D, Duddy, Steven K, Zhang, Can, Nguyen, Phuong D, Becker, Ann, Vo, Uyen, Masliah, Deborah, Monte, Louise, Klee, Justin B, Echmalian, Corinne M, Xia, Weiming, Quinti, Luisa, Johnson, Graham, Lin, Jiunn H, Kim, Doo Y, Mobley, William C, Rissman, Robert A, Tanzi, Rudolph E

Volltext

A peptide-doxorubicin 'prodrug' activated by prostate-specific antigen selectively kills prostate tumor cells positive for prostate-specific antigen in vivo von Jones, Raymond E, DeFeo-Jones, Deborah, Garsky, Victor M, Wong, Bradley K, Feng, Dong-Mei, Bolyar, Trina, Haskell, Kathleen, Kiefer, David M, Leander, Karen, McAvoy, Elizabeth, Lumma, Patricia, Wai, Jenny, Senderak, Edith T, Motzel, Sherri L, Keenan, Kevin, Zwieten, Matthew Van, Lin, Jiunn H, Freidinger, Roger, Huff, Joel, Oliff, Allen

Volltext

Interconversion pharmacokinetics of simvastatin and its hydroxy acid in dogs: effects of gemfibrozil von Prueksaritanont, Thomayant, Qiu, Yue, Mu, Lillian, Michel, Kimberly, Brunner, Janice, Richards, Karen M, Lin, Jiunn H

Volltext

Inhibition and induction of cytochrome P450 and the clinical implications von LIN, J. H, LU, A. Y. H

Volltext

Using real‐time quantitative TaqMan RT‐PCR to evaluate the role of dexamethasone in gene regulation of rat P‐glycoproteins mdr1a/1b and cytochrome P450 3A1/2 von Mei, Qin, Richards, Karen, Strong‐Basalyga, Kristie, Fauty, Scott E., Taylor, Anne, Yamazaki, Masayo, Prueksaritanont, Thomayant, Lin, Jiunn H., Hochman, Jerome

Volltext

A Naphthyridine Carboxamide Provides Evidence for Discordant Resistance between Mechanistically Identical Inhibitors of HIV-1 Integrase von Hazuda, Daria J., Anthony, Neville J., Gomez, Robert P., Jolly, Samson M., Wai, John S., Zhuang, Linghang, Fisher, Thorsten E., Embrey, Mark, Guare, James P., Egbertson, Melissa S., Vacca, Joseph P., Huff, Joel R., Felock, Peter J., Witmer, Marc V., Stillmock, Kara A., Danovich, Robert, Grobler, Jay, Miller, Michael D., Espeseth, Amy S., Jin, Lixia, I-Wu Chen, Lin, Jiunn H., Kassahun, Kelem, Ellis, Joan D., Wong, Bradley K., Xu, Wei, Pearson, Paul G., Schleif, William A., Cortese, Riccardo, Emini, Emilio, Summa, Vincenzo, Holloway, M. Katharine, Young, Steven D., Coffin, John M.

Volltext

Interindividual variability in inhibition and induction of cytochrome P450 enzymes von Lin, J H, Lu, A Y

Volltext

Interactions of human P-glycoprotein with simvastatin, simvastatin acid, and atorvastatin von Hochman, Jerome H, Pudvah, Nicole, Qiu, Julia, Yamazaki, Masayo, Tang, Cuyue, Lin, Jiunn H, Prueksaritanont, Thomayant

Volltext

A Prostate-specific Antigen (PSA)-activated Vinblastine Prodrug Selectively Kills PSA-secreting Cells in Vivo von DeFeo-Jones, Deborah, Brady, Stephen F, Feng, Dong-Mei, Wong, Bradly K, Bolyar, Trina, Haskell, Kathleen, Kiefer, David M, Leander, Karen, McAvoy, Elizabeth, Lumma, Patricia, Pawluczyk, Joseph M, Wai, Jenny, Motzel, Sherri L, Keenan, Kevin, Van Zwieten, Matthew, Lin, Jiunn H, Garsky, Victor M, Freidinger, Roger, Oliff, Allen, Jones, Raymond E

Volltext

Screening of drug candidates for their drug–drug interaction potential von Rodrigues, A.David, Lin, Jiunn H

Volltext

Role of pharmacokinetics in the discovery and development of indinavir von Lin, Jiunn H.

Volltext

Dose-dependent pharmacokinetics: Experimental observations and theoretical considerations von Lin, Jiunn H.

Volltext