Preclinical Evaluation of GS-9160, a Novel Inhibitor of Human Immunodeficiency Virus Type 1 Integrase von JONES, Gregg S, FANG YU, TSIANG, Manuel, ZEYNALZADEGAN, Ameneh, HESSELGESSER, Joseph, XIAOWU CHEN, CHEN, James, HAOLUN JIN, KIM, Choung U, WRIGHT, Matthew, GELEZIUNAS, Romas

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Design, synthesis, and SAR studies of novel and highly active tri-cyclic HIV integrase inhibitors von Jin, Haolun, Cai, Ruby Z., Schacherer, Laura, Jabri, Salman, Tsiang, Manuel, Fardis, Maria, Chen, Xiaowu, Chen, James M., Kim, Choung U.

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Tricyclic HIV integrase inhibitors V. SAR studies on the benzyl moiety von Jin, Haolun, Metobo, Sammy, Jabri, Salman, Mish, Michael, Lansdown, Rachael, Chen, Xiaowu, Tsiang, Manuel, Wright, Matthew, Kim, Choung U.

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Tricyclic HIV integrase inhibitors: Potent and orally bioavailable C5-aza analogs von Jin, Haolun, Wright, Matthew, Pastor, Richard, Mish, Michael, Metobo, Sammy, Jabri, Salman, Lansdown, Rachael, Cai, Ruby, Pyun, Peter, Tsiang, Manuel, Chen, Xiaowu, Kim, Choung U.

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Antiviral Activity of Bictegravir (GS-9883), a Novel Potent HIV-1 Integrase Strand Transfer Inhibitor with an Improved Resistance Profile von Tsiang, Manuel, Jones, Gregg S, Goldsmith, Joshua, Mulato, Andrew, Hansen, Derek, Kan, Elaine, Tsai, Luong, Bam, Rujuta A, Stepan, George, Stray, Kirsten M, Niedziela-Majka, Anita, Yant, Stephen R, Yu, Helen, Kukolj, George, Cihlar, Tomas, Lazerwith, Scott E, White, Kirsten L, Jin, Haolun

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Long Dissociation of Bictegravir from HIV-1 Integrase-DNA Complexes von White, Kirsten L., Osman, Nathan, Cuadra-Foy, Ernesto, Brenner, Bluma G., Shivakumar, Devleena, Campigotto, Federico, Tsiang, Manuel, Morganelli, Philip A., Novikov, Nikolai, Lazerwith, Scott E., Jin, Haolun, Niedziela-Majka, Anita

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Design, synthesis and evaluation of a series of novel fumagillin analogues von FARDIS, Maria, PYUN, Hyung-Jung, TARIO, James, HAOLUN JIN, KIM, Choung U, RUCKMAN, Judy, YUN LIN, GREENS, Louis, HICKED, Brian

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Discovery of 1,6-Naphthyridines as a Novel Class of Potent and Selective Human Cytomegalovirus Inhibitors von Chan, Laval, Jin, Haolun, Stefanac, Tomislav, Lavallée, Jean-François, Falardeau, Guy, Wang, Wei, Bédard, Jean, May, Suzanne, Yuen, Leonard

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Antiviral Properties of a Series of 1,6-Naphthyridine and 7,8-Dihydroisoquinoline Derivatives Exhibiting Potent Activity against Human Cytomegalovirus von Bedard, J, May, S, L'Heureux, L, Stamminger, T, Copsey, A, Drach, J, Huffman, J, Chan, L, Jin, H, Rando, R F

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POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE von HAOLUN, Jin

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Highly regioselective ring opening of quinolinic[2,3]anhydrides under mild conditions von Metobo, Sammy E., Jabri, Salman Y., Aktoudianakis, Evangelos, Evans, Jared, Jin, Haolun, Kim, Choung U.

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Design and evaluation of dihydroisoquinolines as potent and orally bioavailable human cytomegalovirus inhibitors von Chan, Laval, Stefanac, Tomislav, Turcotte, Nathalie, Hu, Zhuhan, Chen, Yanmin, Bédard, Jean, May, Suzanne, Jin, Haolun

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Synthesis of optically active 2′,3′-dideoxy-3′-oxa-4′-thio-ribonucleoside analogues by transposition of a leaving group on chiral oxathiolanes via a reductive-oxidative process... von Wang, Wei, Jin, Haolun, Mansour, Tarek S.

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Tricyclic HIV integrase inhibitors: VI. SAR studies of ‘benzyl flipped’ C3-substituted pyrroloquinolines von Metobo, Sammy, Mish, Michael, Jin, Haolun, Jabri, Salman, Lansdown, Rachael, Chen, Xiaowu, Tsiang, Manuel, Wright, Matthew, Kim, Choung U.

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Total synthesis of a fully protected palytoxin carboxylic acid von Armstrong, Robert W, Beau, Jean Marie, Cheon, Seung Hoon, Christ, William J, Fujioka, Hiromichi, Ham, Won Hun, Hawkins, Lynn D, Jin, Haolun, Kang, Sung Ho

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Oxidative degradation of L-ascorbic acid acetals to 2′,3′-dideoxy-3′-oxaribofuranosides. Synthesis of enantiomerically pure 2′,3′-dideoxy-3′-oxacytidine stereoisomers as potential... von Belleau, Bernard R., Evans, Colleen A., Tse, H.L.Allan, Jin, Haolun, Dixit, Dilip M., Mansour, Tarek S.

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Expeditious preparation of (−)-2′-deoxy-3′-thiacytidine (3TC) von Humber, David C., Jones, Martin F., Payne, Jeremy J., Ramsay, Michael V.J., Zacharie, Boulos, Jin, Haolun, Siddiqui, Arshad, Evans, Colleen A., Tse, H.L.Allan, Mansour, Tarek S.

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Substituted pyrido[1,2-a]pyrrolo[1,2-d]pyrazines for treating viral infections von Jin, Haolun, Pyun, Hyung-Jung, Ji, Mingzhe, Trejo Martin, Teresa Alejandra, Desai, Manoj C

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Catalytic effect of nickel(II) chloride and palladium(II) acetate on chromium(II)-mediated coupling reaction of iodo olefins with aldehydes von Jin, Haolun, Uenishi, Junichi, Christ, William J, Kishi, Yoshito

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Unexpected effects of Lewis acids in the synthesis of optically pure 2′-deoxy-3′-oxacytidine nucleoside analogues von Jin, Haolun, Tse, H.L.Allan, Evans, Colleen A., Mansour, Tarek S., Beels, Christopher M., Ravenscroft, Paul, Humber, David C., Jones, Martin F., Payne, Jeremy J., Ramsay, Michael V.J.

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