Manganese-Induced Neurotoxicity: New Insights Into the Triad of Protein Misfolding, Mitochondrial Impairment, and Neuroinflammation von Harischandra, Dilshan S, Ghaisas, Shivani, Zenitsky, Gary, Jin, Huajun, Kanthasamy, Arthi, Anantharam, Vellareddy, Kanthasamy, Anumantha G

Volltext

Molecular mechanisms underlying protective effects of quercetin against mitochondrial dysfunction and progressive dopaminergic neurodegeneration in cell culture and MitoPark transg... von Ay, Muhammet, Luo, Jie, Langley, Monica, Jin, Huajun, Anantharam, Vellareddy, Kanthasamy, Arthi, Kanthasamy, Anumantha G.

Volltext

Mitochondria-targeted antioxidants for treatment of Parkinson's disease: Preclinical and clinical outcomes von Jin, Huajun, Kanthasamy, Arthi, Ghosh, Anamitra, Anantharam, Vellareddy, Kalyanaraman, Balaraman, Kanthasamy, Anumantha G.

Volltext

Manganese promotes the aggregation and prion-like cell-to-cell exosomal transmission of α-synuclein von Harischandra, Dilshan S, Rokad, Dharmin, Neal, Matthew L, Ghaisas, Shivani, Manne, Sireesha, Sarkar, Souvarish, Panicker, Nikhil, Zenitsky, Gary, Jin, Huajun, Lewis, Mechelle, Huang, Xuemei, Anantharam, Vellareddy, Kanthasamy, Arthi, Kanthasamy, Anumantha G

Volltext

Prokineticin‐2 promotes chemotaxis and alternative A2 reactivity of astrocytes von Neal, Matthew, Luo, Jie, Harischandra, Dilshan S., Gordon, Richard, Sarkar, Souvarish, Jin, Huajun, Anantharam, Vellareddy, Désaubry, Laurent, Kanthasamy, Anumantha, Kanthasamy, Arthi

Volltext

Manganese activates NLRP3 inflammasome signaling and propagates exosomal release of ASC in microglial cells von Sarkar, Souvarish, Rokad, Dharmin, Malovic, Emir, Luo, Jie, Harischandra, Dilshan S, Jin, Huajun, Anantharam, Vellareddy, Huang, Xuemei, Lewis, Mechelle, Kanthasamy, Arthi, Kanthasamy, Anumantha G

Volltext

Organophosphate pesticide chlorpyrifos impairs STAT1 signaling to induce dopaminergic neurotoxicity: Implications for mitochondria mediated oxidative stress signaling events von Singh, Neeraj, Lawana, Vivek, Luo, Jie, Phong, Phang, Abdalla, Ahmed, Palanisamy, Bharathi, Rokad, Dharmin, Sarkar, Souvarish, Jin, Huajun, Anantharam, Vellareddy, Kanthasamy, Anumantha G., Kanthasamy, Arthi

Volltext

Mito-Apocynin Prevents Mitochondrial Dysfunction, Microglial Activation, Oxidative Damage, and Progressive Neurodegeneration in MitoPark Transgenic Mice von Langley, Monica, Ghosh, Anamitra, Charli, Adhithiya, Sarkar, Souvarish, Ay, Muhammet, Luo, Jie, Zielonka, Jacek, Brenza, Timothy, Bennett, Brian, Jin, Huajun, Ghaisas, Shivani, Schlichtmann, Benjamin, Kim, Dongsuk, Anantharam, Vellareddy, Kanthasamy, Arthi, Narasimhan, Balaji, Kalyanaraman, Balaraman, Kanthasamy, Anumantha G

Volltext

Modified CAR T cells targeting membrane-proximal epitope of mesothelin enhances the antitumor function against large solid tumor von Zhang, Zhiwei, Jiang, Duqing, Yang, Huan, He, Zhou, Liu, Xiangzhen, Qin, Wenxia, Li, Linfang, Wang, Chao, Li, Yang, Li, He, Xu, Hai, Jin, Huajun, Qian, Qijun

Volltext

Mechanistic Interplay Between Autophagy and Apoptotic Signaling in Endosulfan-Induced Dopaminergic Neurotoxicity: Relevance to the Adverse Outcome Pathway in Pesticide Neurotoxicit... von Song, Chunjuan, Charli, Adhithiya, Luo, Jie, Riaz, Zainab, Jin, Huajun, Anantharam, Vellareddy, Kanthasamy, Arthi, Kanthasamy, Anumantha G

Volltext

Mitochondrial stress-induced H4K12 hyperacetylation dysregulates transcription in Parkinson's disease von Huang, Minhong, Jin, Huajun, Anantharam, Vellareddy, Kanthasamy, Arthi, Kanthasamy, Anumantha G

Volltext

Protein kinase Cδ upregulation in microglia drives neuroinflammatory responses and dopaminergic neurodegeneration in experimental models of Parkinson's disease von Gordon, Richard, Singh, Neeraj, Lawana, Vivek, Ghosh, Anamitra, Harischandra, Dilshan S, Jin, Huajun, Hogan, Colleen, Sarkar, Souvarish, Rokad, Dharmin, Panicker, Nikhil, Anantharam, Vellareddy, Kanthasamy, Anumantha G, Kanthasamy, Arthi

Volltext

Prokineticin-2 upregulation during neuronal injury mediates a compensatory protective response against dopaminergic neuronal degeneration von Gordon, Richard, Neal, Matthew L., Luo, Jie, Langley, Monica R., Harischandra, Dilshan S., Panicker, Nikhil, Charli, Adhithiya, Jin, Huajun, Anantharam, Vellareddy, Woodruff, Trent M., Zhou, Qun-Yong, Kanthasamy, Anumantha G., Kanthasamy, Arthi

Volltext

Mechanistic Insights Into Gut Microbiome Dysbiosis-Mediated Neuroimmune Dysregulation and Protein Misfolding and Clearance in the Pathogenesis of Chronic Neurodegenerative Disorder... von Padhi, Piyush, Worth, Carter, Zenitsky, Gary, Jin, Huajun, Sambamurti, Kumar, Anantharam, Vellareddy, Kanthasamy, Arthi, Kanthasamy, Anumantha G

Volltext

Microglial immune regulation by epigenetic reprogramming through histone H3K27 acetylation in neuroinflammation von Huang, Minhong, Malovic, Emir, Ealy, Alyssa, Jin, Huajun, Anantharam, Vellareddy, Kanthasamy, Arthi, Kanthasamy, Anumantha G

Volltext

Nanoneuromedicines for degenerative, inflammatory, and infectious nervous system diseases von Gendelman, Howard E, Anantharam, Vellareddy, PhD, Bronich, Tatiana, Ghaisas, Shivani, Jin, Huajun, PhD, Kanthasamy, Anumantha G., PhD, Liu, Xinming, McMillan, JoEllyn, Mosley, R. Lee, Narasimhan, Balaji, PhD, Mallapragada, Surya K., PhD

Volltext

Nuclear pore and nucleocytoplasmic transport impairment in oxidative stress-induced neurodegeneration: relevance to molecular mechanisms in Pathogenesis of Parkinson's and other re... von Riaz, Zainab, Richardson, Gabriel S, Jin, Huajun, Zenitsky, Gary, Anantharam, Vellareddy, Kanthasamy, Arthi, Kanthasamy, Anumantha G

Volltext

Emerging neurotoxic mechanisms in environmental factors-induced neurodegeneration von Kanthasamy, Anumantha, Jin, Huajun, Anantharam, Vellareddy, Sondarva, Gautam, Rangasamy, Velusamy, Rana, Ajay, Kanthasamy, Arthi

Volltext

MitoPark transgenic mouse model recapitulates the gastrointestinal dysfunction and gut-microbiome changes of Parkinson’s disease von Ghaisas, Shivani, Langley, Monica R., Palanisamy, Bharathi N., Dutta, Somak, Narayanaswamy, Kirthi, Plummer, Paul J., Sarkar, Souvarish, Ay, Muhammet, Jin, Huajun, Anantharam, Vellareddy, Kanthasamy, Arthi, Kanthasamy, Anumantha G.

Volltext

Mito-metformin protects against mitochondrial dysfunction and dopaminergic neuronal degeneration by activating upstream PKD1 signaling in cell culture and MitoPark animal models of... von Ay, Muhammet, Charli, Adhithiya, Langley, Monica, Jang, Ahyoung, Padhi, Piyush, Jin, Huajun, Anantharam, Vellareddy, Kalyanaraman, Balaraman, Kanthasamy, Arthi, Kanthasamy, Anumantha G

Volltext