MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors von Jessen, Walter J, Miller, Shyra J, Jousma, Edwin, Wu, Jianqiang, Rizvi, Tilat A, Brundage, Meghan E, Eaves, David, Widemann, Brigitte, Kim, Mi-Ok, Dombi, Eva, Sabo, Jessica, Hardiman Dudley, Atira, Niwa-Kawakita, Michiko, Page, Grier P, Giovannini, Marco, Aronow, Bruce J, Cripe, Timothy P, Ratner, Nancy

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Insertional Mutagenesis Identifies a STAT3/Arid1b/β-catenin Pathway Driving Neurofibroma Initiation von Wu, Jianqiang, Keng, Vincent W., Patmore, Deanna M., Kendall, Jed J., Patel, Ami V., Jousma, Edwin, Jessen, Walter J., Choi, Kwangmin, Tschida, Barbara R., Silverstein, Kevin A.T., Fan, Danhua, Schwartz, Eric B., Fuchs, James R., Zou, Yuanshu, Kim, Mi-Ok, Dombi, Eva, Levy, David E., Huang, Gang, Cancelas, Jose A., Stemmer-Rachamimov, Anat O., Spinner, Robert J., Largaespada, David A., Ratner, Nancy

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Prolonged exposure to reduced levels of androgen accelerates prostate cancer progression in Nkx3.1; pten mutant mice von BANACH-PETROSKY, Whitney, JESSEN, Walter J, OUYANG, Xuesong, HUI GAO, RAO, Jayashree, QUINN, John, ARONOW, Bruce J, ABATE-SHEN, Cory

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The SWI/SNF ATPase Brm Is a Gatekeeper of Proliferative Control in Prostate Cancer von HUI SHEN, POWERS, Nathan, ARONOW, Bruce J, ROSSON, Gary, WEISSMAN, Bernard, MUCHARDT, Christian, YANIV, Moshe, KNUDSEN, Karen E, SAINI, Nitin, COMSTOCK, Clay E. S, SHARMA, Ankur, WEAVER, Katherine, REVELO, Monica P, GERALD, William, WILLIAMS, Erin, JESSEN, Walter J

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Gene Expression Analysis Identifies Potential Biomarkers of Neurofibromatosis Type 1 Including Adrenomedullin von HUMMEL, Trent R, JESSEN, Walter J, SCHORRY, Elizabeth K, RATNER, Nancy, MILLER, Shyra J, KLUWE, Lan, MAUTNER, Victor F, WALLACE, Margaret R, LAZARO, Conxi, PAGE, Grier P, WORLEY, Paul F, ARONOW, Bruce J

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Editor's Note: Activator Protein-1 Transcription Factors Are Associated with Progression and Recurrence of Prostate Cancer von Ouyang, Xuesong, Jessen, Walter J, Al-Ahmadie, Hikmat, Serio, Angel M, Lin, Yong, Shih, Weichung-Joseph, Reuter, Victor E, Scardino, Peter T, Shen, Michael M, Aronow, Bruce J, Vickers, Andrew J, Gerald, William L, Abate-Shen, Cory

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Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data von Liu, Xiangdong, Jessen, Walter J, Sivaganesan, Siva, Aronow, Bruce J, Medvedovic, Mario

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PTEN and NF1 Inactivation in Schwann Cells Produces a Severe Phenotype in the Peripheral Nervous System That Promotes the Development and Malignant Progression of Peripheral Nerve... von KENG, Vincent W, RAHRMANN, Eric P, WATSON, Adrienne L, TSCHIDA, Barbara R, MOERTEL, Christopher L, JESSEN, Walter J, RIZVI, Tilat A, COLLINS, Margaret H, RATNER, Nancy, LARGAESPADA, David A

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Ras-Driven Transcriptome Analysis Identifies Aurora Kinase A as a Potential Malignant Peripheral Nerve Sheath Tumor Therapeutic Target von PATEL, Ami V, EAVES, David, MILLER, Shyra J, RATNER, Nancy, JESSEN, Walter J, RIZVI, Tilat A, ECSEDY, Jeffrey A, QIAN, Mark G, ARONOW, Bruce J, PERENTESIS, John P, SERRA, Eduard, CRIPE, Timothy P

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Activator Protein-1 Transcription Factors Are Associated with Progression and Recurrence of Prostate Cancer von XUESONG OUYANG, JESSEN, Walter J, VICKERS, Andrew J, GERALD, William L, ABATE-SHEN, Cory, AL-AHMADIE, Hikmat, SERIO, Angel M, YONG LIN, SHIH, Weichung-Joseph, REUTER, Victor E, SCARDINO, Peter T, SHEN, Michael M, ARONOW, Bruce J

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Therapeutic Potential of HSP90 Inhibition for Neurofibromatosis Type 2 von TANAKA, Karo, ESKIN, Ascia, NELSON, Stanley F, RUBENSTEIN, Allan E, GIOVANNINI, Marco, CHAREYRE, Fabrice, JESSEN, Walter J, MANENT, Jan, NIWA-KAWAKITA, Michiko, RUIHONG CHEN, WHITE, Cory H, VITTE, Jeremie, JAFFER, Zahara M

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Integrative genomic analyses of neurofibromatosis tumours identify SOX9 as a biomarker and survival gene von Miller, Shyra J., Jessen, Walter J., Mehta, Tapan, Hardiman, Atira, Sites, Emily, Kaiser, Sergio, Jegga, Anil G., Li, Hua, Upadhyaya, Meena, Giovannini, Marco, Muir, David, Wallace, Margaret R., Lopez, Eva, Serra, Eduard, Nielsen, G. Petur, Lazaro, Conxi, Stemmer‐Rachamimov, Anat, Page, Grier, Aronow, Bruce J., Ratner, Nancy

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Cxcr3-expressing leukocytes are necessary for neurofibroma formation in mice von Fletcher, Jonathan S, Wu, Jianqiang, Jessen, Walter J, Pundavela, Jay, Miller, Jacob A, Dombi, Eva, Kim, Mi-Ok, Rizvi, Tilat A, Chetal, Kashish, Salomonis, Nathan, Ratner, Nancy

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Cyclin D1 Is a Selective Modifier of Androgen-dependent Signaling and Androgen Receptor Function von Comstock, Clay E.S., Augello, Michael A., Schiewer, Matthew J., Karch, Jason, Burd, Craig J., Ertel, Adam, Knudsen, Erik S., Jessen, Walter J., Aronow, Bruce J., Knudsen, Karen E.

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Targeted Cytosine Methylation for in vivo Detection of Protein-DNA Interactions von Carvin, Christopher D., Dhasarathy, Archana, Friesenhahn, Laurie B., Jessen, Walter J., Kladde, Michael P.

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Active PHO5 chromatin encompasses variable numbers of nucleosomes at individual promoters von Kladde, Michael P, Jessen, Walter J, Hoose, Scott A, Kilgore, Jessica A

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Mapping chromatin structure in vivo using DNA methyltransferases von Jessen, Walter J, Dhasarathy, Archana, Hoose, Scott A, Carvin, Christopher D, Risinger, April L, Kladde, Michael P

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Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer von Kaiser, Sergio, Park, Young-Kyu, Franklin, Jeffrey L, Halberg, Richard B, Yu, Ming, Jessen, Walter J, Freudenberg, Johannes, Chen, Xiaodi, Haigis, Kevin, Jegga, Anil G, Kong, Sue, Sakthivel, Bhuvaneswari, Xu, Huan, Reichling, Timothy, Azhar, Mohammad, Boivin, Gregory P, Roberts, Reade B, Bissahoyo, Anika C, Gonzales, Fausto, Bloom, Greg C, Eschrich, Steven, Carter, Scott L, Aronow, Jeremy E, Kleimeyer, John, Kleimeyer, Michael, Ramaswamy, Vivek, Settle, Stephen H, Boone, Braden, Levy, Shawn, Graff, Jonathan M, Doetschman, Thomas, Groden, Joanna, Dove, William F, Threadgill, David W, Yeatman, Timothy J, Coffey, Jr, Robert J, Aronow, Bruce J

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Abstract B32: Cxcr3-expressing leukocytes are necessary for neurofibroma formation in mice von Fletcher, Jonathan S., Wu, Jianqiang, Jessen, Walter J., Pundavela, Jay, Dombi, Eva, Kim, Mi-Ok, Rizvi, Tilat A., Chetal, Kashish, Salomonis, Nathan, Ratner, Nancy

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Mining PubMed for Biomarker-Disease Associations to Guide Discovery von Jessen, Walter, Landschulz, Katherine, Turi, Thomas, Reams, Rachel

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