Modulation of cellular S1P levels with a novel, potent and specific inhibitor of sphingosine kinase-1 von Schnute, Mark E, McReynolds, Matthew D, Kasten, Tom, Yates, Matthew, Jerome, Gina, Rains, John W, Hall, Troii, Chrencik, Jill, Kraus, Michelle, Cronin, Ciaran N, Saabye, Matthew, Highkin, Maureen K, Broadus, Richard, Ogawa, Shinji, Cukyne, Kristin, Zawadzke, Laura E, Peterkin, Vincent, Iyanar, Kaliapan, Scholten, Jeffrey A, Wendling, Jay, Fujiwara, Hideji, Nemirovskiy, Olga, Wittwer, Arthur J, Nagiec, Marek M

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Discovery of a Potent and Selective Sphingosine Kinase 1 Inhibitor through the Molecular Combination of Chemotype-Distinct Screening Hits von Schnute, Mark E, McReynolds, Matthew D, Carroll, Jeffrey, Chrencik, Jill, Highkin, Maureen K, Iyanar, Kaliapan, Jerome, Gina, Rains, John W, Saabye, Matthew, Scholten, Jeffrey A, Yates, Matthew, Nagiec, Marek M

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Bioactivity-Guided Identification of Botanical Inhibitors of Ketohexokinase von Le, MyPhuong T, Lanaspa, Miguel A, Cicerchi, Christina M, Rana, Jatinder, Scholten, Jeffrey D, Hunter, Brandi L, Rivard, Christopher J, Randolph, R Keith, Johnson, Richard J

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Discovery of N‑(4-Fluoro-3-methoxybenzyl)-6-(2-(((2S,5R)‑5-(hydroxymethyl)-1,4-dioxan-2-yl)methyl)‑2H‑tetrazol-5-yl)-2-methylpyrimidine-4-carboxamide. A Highly Selective and Orally... von Ruminski, Peter G, Massa, Mark, Strohbach, Joseph, Hanau, Cathleen E, Schmidt, Michelle, Scholten, Jeffrey A, Fletcher, Theresa R, Hamper, Bruce C, Carroll, Jeffery N, Shieh, Huey S, Caspers, Nicole, Collins, Brandon, Grapperhaus, Margaret, Palmquist, Katherine E, Collins, Joe, Baldus, John E, Hitchcock, Jeffrey, Kleine, H. Peter, Rogers, Michael D, McDonald, Joseph, Munie, Grace E, Messing, Dean M, Portolan, Silvia, Whiteley, Laurence O, Sunyer, Teresa, Schnute, Mark E

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The cytoprotective benefits of a turmeric, quercetin, and rosemary blend through activation of the oxidative stress pathway von Rajgopal, Arun, Roloff, Samantha, Burns, Charlie, Fast, David, Scholten, Jeffrey

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Traditional chinese medicine ingredients Rosa damascena and Poria cocos promote phagocytosis and a dendritic cell phenotype in THP-1 cells von Roloff, Samantha, Scholten, Jeffrey, Chuang, Jennifer, Hu, Chun, Fast, David

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Echinacea purpurea root extract inhibits TNF release in response to Pam3Csk4 in a phosphatidylinositol-3-kinase dependent manner von Fast, David J., Balles, John A., Scholten, Jeffrey D., Mulder, Timothy, Rana, Jatinder

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Evaluation of selected traditional Chinese medical extracts for bone mineral density maintenance: A mechanistic study von Rebhun, John F., Du, Qin, Hood, Molly, Guo, Hailing, Glynn, Kelly M., Cen, Hao, Scholten, Jeffrey D., Tian, Feng, Gui, Min, Li, Minjie, Zhao, Yongfang

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Immunomodulatory effects of Lippia sidoides extract: induction of IL-10 through cAMP and p38 MAPK-dependent mechanisms von Rajgopal, Arun, Rebhun, John F, Burns, Charlie R, Scholten, Jeffrey D, Balles, John A, Fast, David J

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Inhibition of melanin content by Punicalagins in the super fruit pomegranate (Punica granatum) von Rana, Jatinder, Diwakar, Ganesh, Saito, Lisa, Scholten, Jeffrey D, Mulder, Timothy

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Synthesis and biological evaluation of substituted benzoxazoles as inhibitors of mPGES-1: Use of a conformation-based hypothesis to facilitate compound design von Walker, Daniel P., Arhancet, Graciela B., Lu, Hwang-Fun, Heasley, Steven E., Metz, Sue, Kablaoui, Natasha M., Franco, Francisco M., Hanau, Cathleen E., Scholten, Jeffrey A., Springer, John R., Fobian, Yvette M., Carter, Jeffrey S., Xing, Li, Yang, Shengtian, Shaffer, Alexander F., Jerome, Gina M., Baratta, Michael T., Moore, William M., Vazquez, Michael L.

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Identification of a botanical inhibitor of intestinal diacylglyceride acyltransferase 1 activity via in vitro screening and a parallel, randomized, blinded, placebo-controlled clin... von Velliquette, Rodney A, Grann, Kerry, Missler, Stephen R, Patterson, Jennifer, Hu, Chun, Gellenbeck, Kevin W, Scholten, Jeffrey D, Randolph, R Keith

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Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis von SCHNUTE, Mark E, O'BRIEN, Patrick M, CARROLL, Jeffery N, PATT, William C, SHIEH, Huey S, COLLINS, Brandon, PAVLOVSKY, Alexander G, PALMQUIST, Katherine E, ASTON, Karl W, HITCHCOCK, Jeffrey, ROGERS, Michael D, MCDONALD, Joseph, NAHRA, Joe, JOHNSON, Adam R, MUNIE, Grace E, WITTWER, Arthur J, MAN, Chiu-Fai, SETTLE, Steven L, NEMIROVSKIY, Olga, VICKERY, Lillian E, AGAWAL, Arun, DYER, Richard D, SUNYER, Teresa, MORRIS, Mark, HOWARD ROARK, W, HANAU, Cathleen E, RUMINSKI, Peter G, SCHOLTEN, Jeffrey A, FLETCHER, Theresa R, HAMPER, Bruce C

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Craniocervical chiropractic procedures - a précis of upper cervical chiropractic von Woodfield, 3rd, H Charles, York, Craig, Rochester, Roderic P, Bales, Scott, Beebe, Mychal, Salminen, Bryan, Scholten, Jeffrey N

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Synergistic Activation of the Nrf2-ARE Oxidative Stress Response Pathway by a Combination of Botanical Extracts von Missler, Stephen R., Rajgopal, Arun, Roloff, Samantha J., Scholten, Jeffrey D., Burns, Charlie R., Patterson, Jennifer A., Pusateri, Donald J., Gellenbeck, Kevin W., Stern, Nate P., Randolph, R. Keith, Lin, Yumei, Chuang, Jennifer, Kazlova, Valentina, Fast, David J.

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Differential Prenyl Pyrophosphate Binding to Mammalian Protein Geranylgeranyltransferase-I and Protein Farnesyltransferase and Its Consequence on the Specificity of Protein Prenyla... von Yokoyama, Kohei, Zimmerman, Karen, Scholten, Jeffrey, Gelb, Michael H.

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Protein prenylation: from discovery to prospects for cancer treatment von Gelb, Michael H, Scholten, Jeffrey D, Sebolt-Leopold, Judith S

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Mutations in the B12-Binding Region of Methionine Synthase:  How the Protein Controls Methylcobalamin Reactivity von Jarrett, Joseph T, Amaratunga, Mohan, Drennan, Catherine L, Scholten, Jeffrey D, Sands, Richard H, Ludwig, Martha L, Matthews, Rowena G

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Ancestry of the 4-chlorobenzoate dehalogenase: analysis of amino acid sequence identities among families of acyl:adenyl ligases, enoyl-CoA hydratases/isomerases, and acyl-CoA thioe... von Babbitt, Patricia C, Kenyon, George L, Martin, Brian M, Charest, Hugues, Slyvestre, Michel, Scholten, Jeffrey D, Chang, Kai Hsuan, Liang, Po Huang, Dunaway-Mariano, Debra

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Inhibition of melanin production by a combination of Siberian larch and pomegranate fruit extracts von Diwakar, Ganesh, Rana, Jatinder, Scholten, Jeffrey D.

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