Optimization of a PEGylated Glucuronide-Monomethylauristatin E Linker for Antibody-Drug Conjugates von Burke, Patrick J, Hamilton, Joseph Z, Jeffrey, Scott C, Hunter, Joshua H, Doronina, Svetlana O, Okeley, Nicole M, Miyamoto, Jamie B, Anderson, Martha E, Stone, Ivan J, Ulrich, Michelle L, Simmons, Jessica K, McKinney, Erica E, Senter, Peter D, Lyon, Robert P

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Contribution of Linker Stability to the Activities of Anticancer Immunoconjugates von Alley, Stephen C, Benjamin, Dennis R, Jeffrey, Scott C, Okeley, Nicole M, Meyer, Damon L, Sanderson, Russell J, Senter, Peter D

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Development of orally active inhibitors of protein and cellular fucosylation von Okeley, Nicole M., Alley, Stephen C., Anderson, Martha E., Boursalian, Tamar E., Burke, Patrick J., Emmerton, Kim M., Jeffrey, Scott C., Klussman, Kerry, Law, Che-Leung, Sussman, Django, Toki, Brian E., Westendorf, Lori, Zeng, Weiping, Zhang, Xinqun, Benjamin, Dennis R., Senter, Peter D.

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Metabolic Engineering of Monoclonal Antibody Carbohydrates for Antibody–Drug Conjugation von Okeley, Nicole M, Toki, Brian E, Zhang, Xinqun, Jeffrey, Scott C, Burke, Patrick J, Alley, Stephen C, Senter, Peter D

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Development of Novel Quaternary Ammonium Linkers for Antibody-Drug Conjugates von Burke, Patrick J, Hamilton, Joseph Z, Pires, Thomas A, Setter, Jocelyn R, Hunter, Joshua H, Cochran, Julia H, Waight, Andrew B, Gordon, Kristine A, Toki, Brian E, Emmerton, Kim K, Zeng, Weiping, Stone, Ivan J, Senter, Peter D, Lyon, Robert P, Jeffrey, Scott C

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Glucuronide-Linked Antibody-Tubulysin Conjugates Display Activity in MDR + and Heterogeneous Tumor Models von Burke, Patrick J, Hamilton, Joseph Z, Pires, Thomas A, Lai, Holden W H, Leiske, Christopher I, Emmerton, Kim K, Waight, Andrew B, Senter, Peter D, Lyon, Robert P, Jeffrey, Scott C

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SGN-CD33A: a novel CD33-targeting antibody–drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML von Kung Sutherland, May S., Walter, Roland B., Jeffrey, Scott C., Burke, Patrick J., Yu, Changpu, Kostner, Heather, Stone, Ivan, Ryan, Maureen C., Sussman, Django, Lyon, Robert P., Zeng, Weiping, Harrington, Kimberly H., Klussman, Kerry, Westendorf, Lori, Meyer, David, Bernstein, Irwin D., Senter, Peter D., Benjamin, Dennis R., Drachman, Jonathan G., McEarchern, Julie A.

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A Potent Anti-CD70 Antibody–Drug Conjugate Combining a Dimeric Pyrrolobenzodiazepine Drug with Site-Specific Conjugation Technology von Jeffrey, Scott C, Burke, Patrick J, Lyon, Robert P, Meyer, David W, Sussman, Django, Anderson, Martha, Hunter, Joshua H, Leiske, Chris I, Miyamoto, Jamie B, Nicholas, Nicole D, Okeley, Nicole M, Sanderson, Russell J, Stone, Ivan J, Zeng, Weiping, Gregson, Stephen J, Masterson, Luke, Tiberghien, Arnaud C, Howard, Philip W, Thurston, David E, Law, Che-Leung, Senter, Peter D

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The Methylene Alkoxy Carbamate Self-Immolative Unit: Utilization for the Targeted Delivery of Alcohol-Containing Payloads with Antibody-Drug Conjugates von Kolakowski, Robert V., Haelsig, Karl T., Emmerton, Kim K., Leiske, Chris I., Miyamoto, Jamie B., Cochran, Julia H., Lyon, Robert P., Senter, Peter D., Jeffrey, Scott C.

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Development of Novel Antibody-Camptothecin Conjugates von Lyski, Ryan D, Bou, Lauren B, Lau, Uland Y, Meyer, David W, Cochran, Julia H, Okeley, Nicole M, Emmerton, Kim K, Zapata, Francisco, Simmons, Jessica K, Trueblood, Esther S, Ortiz, David J, Zaval, Margo C, Snead, Katie M, Jin, Steven, Farr, Lauren M, Ryan, Maureen C, Senter, Peter D, Jeffrey, Scott C

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Structure-activity relationships of tubulysin analogues von Courter, Joel R., Hamilton, Joseph Z., Hendrick, Nathaniel R., Zaval, Margo, Waight, Andrew B., Lyon, Robert P., Senter, Peter D., Jeffrey, Scott C., Burke, Patrick J.

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Improving Antibody‐Tubulysin Conjugates through Linker Chemistry and Site‐Specific Conjugation von Hamilton, Joseph Z., Pires, Thomas A., Mitchell, Jamie A., Cochran, Julia H., Emmerton, Kim K., Zaval, Margo, Stone, Ivan J., Anderson, Martha E., Jin, Steven, Waight, Andrew B., Lyon, Robert P., Senter, Peter D., Jeffrey, Scott C., Burke, Patrick J.

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Design, Synthesis, and Biological Evaluation of Antibody−Drug Conjugates Comprised of Potent Camptothecin Analogues von Burke, Patrick J, Senter, Peter D, Meyer, David W, Miyamoto, Jamie B, Anderson, Martha, Toki, Brian E, Manikumar, Govindarajan, Wani, Mansukh C, Kroll, David J, Jeffrey, Scott C

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Development and Properties of β-Glucuronide Linkers for Monoclonal Antibody−Drug Conjugates von Jeffrey, Scott C, Andreyka, Jamie B, Bernhardt, Starr X, Kissler, Kim M, Kline, Toni, Lenox, Joel S, Moser, Ruth F, Nguyen, Minh T, Okeley, Nicole M, Stone, Ivan J, Zhang, Xinqun, Senter, Peter D

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Expanded Utility of the β-Glucuronide Linker: ADCs That Deliver Phenolic Cytotoxic Agents von Jeffrey, Scott C, De Brabander, Jef, Miyamoto, Jamie, Senter, Peter D

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Synthesis of the northern sector (C8–C19) of rapamycin via Chan rearrangement and oxidation of an α-acyloxyacetate von White, James D., Jeffrey, Scott C.

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Design, Synthesis, and in Vitro Evaluation of Dipeptide-Based Antibody Minor Groove Binder Conjugates von Jeffrey, Scott C, Torgov, Michael Y, Andreyka, Jamie B, Boddington, Laura, Cerveny, Charles G, Denny, William A, Gordon, Kristine A, Gustin, Darin, Haugen, Jennifer, Kline, Toni, Nguyen, Minh T, Senter, Peter D

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Minor groove binder antibody conjugates employing a water soluble β-glucuronide linker von Jeffrey, Scott C., Nguyen, Minh T., Moser, Ruth F., Meyer, Damon L., Miyamoto, Jamie B., Senter, Peter D.

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Dipeptide-based highly potent doxorubicin antibody conjugates von Jeffrey, Scott C., Nguyen, Minh T., Andreyka, Jamie B., Meyer, Damon L., Doronina, Svetlana O., Senter, Peter D.

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Novel immunoconjugates comprised of streptonigrin and 17-amino-geldanamycin attached via a dipeptide- p-aminobenzyl-amine linker system von Burke, Patrick J., Toki, Brian E., Meyer, David W., Miyamoto, Jamie B., Kissler, Kim M., Anderson, Martha, Senter, Peter D., Jeffrey, Scott C.

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