Intranasal vaccination promotes detrimental Th17-mediated immunity against influenza infection von Maroof, Asher, Yorgensen, Yvonne M, Li, Yufeng, Evans, Jay T

Volltext

MPL Adjuvant Contains Competitive Antagonists of Human TLR4 von Wang, Yi-Qi, Bazin-Lee, Hélène, Evans, Jay T, Casella, Carolyn R, Mitchell, Thomas C

Volltext

Immunoregulatory Activity of the Natural Product Laminarin Varies Widely as a Result of Its Physical Properties von Smith, Alyson J, Graves, Bridget, Child, Robert, Rice, Peter J, Ma, Zuchao, Lowman, Douglas W, Ensley, Harry E, Ryter, Kendal T, Evans, Jay T, Williams, David L

Volltext

Design of Trehalose‐Based Amide/Sulfonamide C‐type Lectin Receptor Signaling Compounds von Rasheed, Omer K., Buhl, Cassandra, Evans, Jay T., Ryter, Kendal T.

Volltext

Novel Lipidated Imidazoquinoline TLR7/8 Adjuvants Elicit Influenza-Specific Th1 Immune Responses and Protect Against Heterologous H3N2 Influenza Challenge in Mice von Miller, Shannon M, Cybulski, Van, Whitacre, Margaret, Bess, Laura S, Livesay, Mark T, Walsh, Lois, Burkhart, David, Bazin, Hélène G, Evans, Jay T

Volltext

Development of a TLR7/8 agonist adjuvant formulation to overcome early life hyporesponsiveness to DTaP vaccination von Dowling, David J., Barman, Soumik, Smith, Alyson J., Borriello, Francesco, Chaney, Danielle, Brightman, Spencer E., Melhem, Gandolina, Brook, Byron, Menon, Manisha, Soni, Dheeraj, Schüller, Simone, Siram, Karthik, Nanishi, Etsuro, Bazin, Hélène G., Burkhart, David J., Levy, Ofer, Evans, Jay T.

Volltext

Systematic Evaluation of Regiochemistry and Lipidation of Aryl Trehalose Mincle Agonists von Riel, Asia Marie S, Rungelrath, Viktoria, Elwaie, Tamer A, Rasheed, Omer K, Hicks, Linda, Ettenger, George, You, Dai-Chi, Smith, Mira, Buhl, Cassandra, Abdelwahab, Walid, Miller, Shannon M, Smith, Alyson J, Burkhart, David, Evans, Jay T, Ryter, Kendal T

Volltext

Towards Precision Vaccines: Lessons From the Second International Precision Vaccines Conference von Soni, Dheeraj, Van Haren, Simon D, Idoko, Olubukola T, Evans, Jay T, Diray-Arce, Joann, Dowling, David J, Levy, Ofer

Volltext

Intranasal administration of a synthetic TLR4 agonist INI-2004 significantly reduces allergy symptoms following therapeutic administration in a murine model of allergic sensitizati... von Jackson, Konner J, Buhl, Cassandra, Miller, Shannon M, Khalaf, Juhienah K, Ward, Janine, Sands, Cherrokee, Walsh, Lois, Whitacre, Margaret, Burkhart, David J, Bazin-Lee, Hélène G, Evans, Jay T

Volltext

Evaluation of novel synthetic TLR7/8 agonists as vaccine adjuvants von Smith, Alyson J, Li, Yufeng, Bazin, Hélène G, St-Jean, Julien R, Larocque, Daniel, Evans, Jay T, Baldridge, Jory R

Volltext

Advancing Adjuvants for Mycobacterium tuberculosis Therapeutics von Enriquez, Ana B, Izzo, Angelo, Miller, Shannon M, Stewart, Erica L, Mahon, Robert N, Frank, Daniel J, Evans, Jay T, Rengarajan, Jyothi, Triccas, James A

Volltext

Species-Specific Structural Requirements of Alpha-Branched Trehalose Diester Mincle Agonists von Smith, Alyson J, Miller, Shannon M, Buhl, Cassandra, Child, Robert, Whitacre, Margaret, Schoener, Roman, Ettenger, George, Burkhart, David, Ryter, Kendal, Evans, Jay T

Volltext

Co-Delivery of a Novel Lipidated TLR7/8 Agonist and Hemagglutinin-Based Influenza Antigen Using Silica Nanoparticles Promotes Enhanced Immune Responses von Abdelwahab, Walid M, Auclair, Sarah, Borgogna, Timothy, Siram, Karthik, Riffey, Alexander, Bazin, Hélène G, Cottam, Howard B, Hayashi, Tomoko, Evans, Jay T, Burkhart, David J

Volltext

Selective TRIF-dependent signaling by a synthetic toll-like receptor 4 agonist von Bowen, William S, Minns, Laurie A, Johnson, David A, Mitchell, Thomas C, Hutton, Melinda M, Evans, Jay T

Volltext

Vaccination with Mincle agonist UM-1098 and mycobacterial antigens induces protective Th1 and Th17 responses von Rungelrath, Viktoria, Ahmed, Mushtaq, Hicks, Linda, Miller, Shannon M., Ryter, Kendal T., Montgomery, Kyle, Ettenger, George, Riffey, Alexander, Abdelwahab, Walid M., Khader, Shabaana Abdul, Evans, Jay T.

Volltext

Methylglycol chitosan and a synthetic TLR4 agonist enhance immune responses to influenza vaccine administered sublingually von Spinner, Justin L, Oberoi, Hardeep S, Yorgensen, Yvonne M, Poirier, Danielle S, Burkhart, David J, Plante, Martin, Evans, Jay T

Volltext

Co-Delivery of Novel Synthetic TLR4 and TLR7/8 Ligands Adsorbed to Aluminum Salts Promotes Th1-Mediated Immunity against Poorly Immunogenic SARS-CoV-2 RBD von Siram, Karthik, Lathrop, Stephanie K, Abdelwahab, Walid M, Tee, Rebekah, Davison, Clara J, Partlow, Haley A, Evans, Jay T, Burkhart, David J

Volltext

Using Dual Toll-like Receptor Agonism to Drive Th1-Biased Response in a Squalene- and α-Tocopherol-Containing Emulsion for a More Effective SARS-CoV-2 Vaccine von Short, Kristopher K, Lathrop, Stephanie K, Davison, Clara J, Partlow, Haley A, Kaiser, Johnathan A, Tee, Rebekah D, Lorentz, Elizabeth B, Evans, Jay T, Burkhart, David J

Volltext

A lipidated TLR7/8 adjuvant enhances the efficacy of a vaccine against fentanyl in mice von Miller, Shannon M., Crouse, Bethany, Hicks, Linda, Amin, Hardik, Cole, Shelby, Bazin, Helene G., Burkhart, David J., Pravetoni, Marco, Evans, Jay T.

Volltext

A TLR7/8 agonist increases efficacy of anti-fentanyl vaccines in rodent and porcine models von Crouse, Bethany, Miller, Shannon M., Muelken, Peter, Hicks, Linda, Vigliaturo, Jennifer R., Marker, Cheryl L., Guedes, Alonso G. P., Pentel, Paul R., Evans, Jay T., LeSage, Mark G., Pravetoni, Marco

Volltext