Discovery and Characterization of SY-1365, a Selective, Covalent Inhibitor of CDK7 von Hu, Shanhu, Marineau, Jason J, Rajagopal, Nisha, Hamman, Kristin B, Choi, Yoon Jong, Schmidt, Darby R, Ke, Nan, Johannessen, Liv, Bradley, Michael J, Orlando, David A, Alnemy, Sydney R, Ren, Yixuan, Ciblat, Stephane, Winter, Dana K, Kabro, Anzhelika, Sprott, Kevin T, Hodgson, J Graeme, Fritz, Christian C, Carulli, John P, di Tomaso, Emmanuelle, Olson, Eric R

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Gene expression–based discovery of atovaquone as a STAT3 inhibitor and anticancer agent von Xiang, Michael, Kim, Haesook, Ho, Vincent T., Walker, Sarah R., Bar-Natan, Michal, Anahtar, Melodi, Liu, Suhu, Toniolo, Patricia A., Kroll, Yasmin, Jones, Nichole, Giaccone, Zachary T., Heppler, Lisa N., Ye, Darwin Q., Marineau, Jason J., Shaw, Daniel, Bradner, James E., Blonquist, Traci, Neuberg, Donna, Hetz, Claudio, Stone, Richard M., Soiffer, Robert J., Frank, David A.

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Discovery of SY-5609: A Selective, Noncovalent Inhibitor of CDK7 von Marineau, Jason J, Hamman, Kristin B, Hu, Shanhu, Alnemy, Sydney, Mihalich, Janessa, Kabro, Anzhelika, Whitmore, Kenneth Matthew, Winter, Dana K, Roy, Stephanie, Ciblat, Stephane, Ke, Nan, Savinainen, Anneli, Wilsily, Ashraf, Malojcic, Goran, Zahler, Robert, Schmidt, Darby, Bradley, Michael J, Waters, Nigel J, Chuaqui, Claudio

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Genome-wide localization of small molecules von Anders, Lars, Guenther, Matthew G, Qi, Jun, Fan, Zi Peng, Marineau, Jason J, Rahl, Peter B, Lovén, Jakob, Sigova, Alla A, Smith, William B, Lee, Tong Ihn, Bradner, James E, Young, Richard A

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Selective inhibition of CDK7 reveals high-confidence targets and new models for TFIIH function in transcription von Rimel, Jenna K, Poss, Zachary C, Erickson, Benjamin, Maas, Zachary L, Ebmeier, Christopher C, Johnson, Jared L, Decker, Tim-Michael, Yaron, Tomer M, Bradley, Michael J, Hamman, Kristin B, Hu, Shanhu, Malojcic, Goran, Marineau, Jason J, White, Peter W, Brault, Martine, Tao, Limei, DeRoy, Patrick, Clavette, Christian, Nayak, Shraddha, Damon, Leah J, Kaltheuner, Ines H, Bunch, Heeyoun, Cantley, Lewis C, Geyer, Matthias, Iwasa, Janet, Dowell, Robin D, Bentley, David L, Old, William M, Taatjes, Dylan J

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Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors von Yu, Wenyu, Chory, Emma J., Wernimont, Amy K., Tempel, Wolfram, Scopton, Alex, Federation, Alexander, Marineau, Jason J., Qi, Jun, Barsyte-Lovejoy, Dalia, Yi, Joanna, Marcellus, Richard, Iacob, Roxana E., Engen, John R., Griffin, Carly, Aman, Ahmed, Wienholds, Erno, Li, Fengling, Pineda, Javier, Estiu, Guillermina, Shatseva, Tatiana, Hajian, Taraneh, Al-awar, Rima, Dick, John E., Vedadi, Masoud, Brown, Peter J., Arrowsmith, Cheryl H., Bradner, James E., Schapira, Matthieu

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Biased Multicomponent Reactions to Develop Novel Bromodomain Inhibitors von McKeown, Michael R, Shaw, Daniel L, Fu, Harry, Liu, Shuai, Xu, Xiang, Marineau, Jason J, Huang, Yibo, Zhang, Xiaofeng, Buckley, Dennis L, Kadam, Asha, Zhang, Zijuan, Blacklow, Stephen C, Qi, Jun, Zhang, Wei, Bradner, James E

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Structure-Guided DOT1L Probe Optimization by Label-Free Ligand Displacement von Yi, Joanna S, Federation, Alexander J, Qi, Jun, Dhe-Paganon, Sirano, Hadler, Michael, Xu, Xiang, St. Pierre, Roodolph, Varca, Anthony C, Wu, Lei, Marineau, Jason J, Smith, William B, Souza, Amanda, Chory, Emma J, Armstrong, Scott A, Bradner, James E

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7,9-Diaryl-1,6,8-trioxaspiro[4.5]dec-3-en-2-ones: Readily accessible and highly potent anticancer compounds von D’Erasmo, Michael P., Smith, William B., Munoz, Alberto, Mohandas, Poornima, Au, Andrew S., Marineau, Jason J., Quadri, Luis E.N., Bradner, James E., Murelli, Ryan P.

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Development and Evaluation of a Solid-Supported Cyclobutadieneiron Tricarbonyl Complex for Parallel Synthesis Applications von Marineau, Jason J, Snapper, Marc L

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Corrigendum: Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors von Yu, Wenyu, Chory, Emma J, Wernimont, Amy K, Tempel, Wolfram, Scopton, Alex, Federation, Alexander, Marineau, Jason J, Qi, Jun, Barsyte-lovejoy, Dalia, Yi, Joanna, Marcellus, Richard, Iacob, Roxana E, Engen, John R, Griffin, Carly, Aman, Ahmed, Wienholds, Erno, Li, Fengling, Pineda, Javier, Estiu, Guillermina, Shatseva, Tatiana, Hajian, Taraneh, Al-awar, Rima, Dick, John E, Vedadi, Masoud, Brown, Peter J, Arrowsmith, Cheryl H, Bradner, James E, Schapira, Matthieu

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Abstract 3230: Genome-wide localization of anti-cancer drugs von Anders, Lars, Guenther, Matthew G., Qi, Jun, Fan, Zi Peng, Marineau, Jason J., Rahl, Peter B., Lovén, Jakob, Sigova, Alla A., Smith, William B., Lee, Tong Ihn, Bradner, James E., Young, Richard A.

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Genome-wide determination of drug localization von Anders, Lars, Guenther, Matthew G, Qi, Jun, Fan, Zi Peng, Marineau, Jason J, Rahl, Peter B, Lovén, Jakob, Sigova, Alla A, Smith, William B, Lee, Tong Ihn, Bradner, James E, Young, Richard A

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Genome-wide determination of drug localization von Anders, Lars, Guenther, Matthew G., Qi, Jun, Fan, Zi Peng, Marineau, Jason J., Rahl, Peter B., Lovén, Jakob, Sigova, Alla A., Smith, William B., Lee, Tong Ihn, Bradner, James E., Young, Richard A.

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Biased Multicomponent Reactions to Develop Novel Bromodomain Inhibitors von McKeown, Michael R, Shaw, Daniel L, Fu, Harry, Liu, Shuai, Xu, Xiang, Marineau, Jason J, Huang, Yibo, Zhang, Xiaofeng, Buckley, Dennis L, Kadam, Asha, Zhang, Zijuan, Blacklow, Stephen C, Qi, Jun, Zhang, Wei, Bradner, James E

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Structure-Guided DOT1L Probe Optimization by Label-Free Ligand Displacement von Yi, Joanna S, Federation, Alexander J, Qi, Jun, Dhe-Paganon, Sirano, Hadler, Michael, Xu, Xiang, St. Pierre, Roodolph, Varca, Anthony C, Wu, Lei, Marineau, Jason J, Smith, William B, Souza, Amanda, Chory, Emma J, Armstrong, Scott A, Bradner, James E

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Correction: Corrigendum: Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors von Yu, Wenyu, Chory, Emma J., Wernimont, Amy K., Tempel, Wolfram, Scopton, Alex, Federation, Alexander, Marineau, Jason J., Qi, Jun, Barsyte-Lovejoy, Dalia, Yi, Joanna, Marcellus, Richard, Iacob, Roxana E., Engen, John R., Griffin, Carly, Aman, Ahmed, Wienholds, Erno, Li, Fengling, Pineda, Javier, Estiu, Guillermina, Shatseva, Tatiana, Hajian, Taraneh, Al-awar, Rima, Dick, John E., Vedadi, Masoud, Brown, Peter J., Arrowsmith, Cheryl H., Bradner, James E., Schapira, Matthieu

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INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) von JASON J MARINEAU, ANZHELIKA KABRO, STEPHANE CIBLAT, MICHAEL BRADLEY, CLAUDIO CHUAQUI

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Inhibitors of cyclin-dependent kinase 7 (CDK7) von Schmidt, Darby, Marineau, Jason J, Sprott, Kevin

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INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) von SCHMIDT, Darby, MARINEAU, Jason, J, SPROTT, Kevin

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