Triglyceride Synthesis by DGAT1 Protects Adipocytes from Lipid-Induced ER Stress during Lipolysis von Chitraju, Chandramohan, Mejhert, Niklas, Haas, Joel T., Diaz-Ramirez, L. Grisell, Grueter, Carrie A., Imbriglio, Jason E., Pinto, Shirly, Koliwad, Suneil K., Walther, Tobias C., Farese, Robert V.

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Nucleophilic Ortho Allylation of Aryl and Heteroaryl Sulfoxides von Eberhart, Andrew J, Imbriglio, Jason E, Procter, David J

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Dual Catalyst Control in the Amino Acid-Peptide-Catalyzed Enantioselective Baylis−Hillman Reaction von Imbriglio, Jason E, Vasbinder, Melissa M, Miller, Scott J

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DGAT2 Inhibition Alters Aspects of Triglyceride Metabolism in Rodents but Not in Non-human Primates von McLaren, David G., Han, Seongah, Murphy, Beth Ann, Wilsie, Larissa, Stout, Steven J., Zhou, Haihong, Roddy, Thomas P., Gorski, Judith N., Metzger, Daniel E., Shin, Myung K., Reilly, Dermot F., Zhou, Heather H., Tadin-Strapps, Marija, Bartz, Steven R., Cumiskey, Anne-Marie, Graham, Thomas H., Shen, Dong-Ming, Akinsanya, Karen O., Previs, Stephen F., Imbriglio, Jason E., Pinto, Shirly

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From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9 von Petrilli, Whitney L., Adam, Gregory C., Erdmann, Roman S., Abeywickrema, Pravien, Agnani, Vijayalakshmi, Ai, Xi, Baysarowich, Jen, Byrne, Noel, Caldwell, John P., Chang, Wonsuk, DiNunzio, Edward, Feng, Zhe, Ford, Rachael, Ha, Sookhee, Huang, Yongcheng, Hubbard, Brian, Johnston, Jennifer M., Kavana, Michael, Lisnock, Jean-Marie, Liang, Rui, Lu, Jun, Lu, Zhijian, Meng, Juncai, Orth, Peter, Palyha, Oksana, Parthasarathy, Gopal, Salowe, Scott P., Sharma, Sujata, Shipman, Jennifer, Soisson, Stephen M., Strack, Alison M., Youm, Hyewon, Zhao, Kake, Zink, Deborah L., Zokian, Hratch, Addona, George H., Akinsanya, Karen, Tata, James R., Xiong, Yusheng, Imbriglio, Jason E.

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Synthesis and Chemoselective Reactivity of 3-Aminocyclopentadienones von Rainier, Jon D, Imbriglio, Jason E

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Examining Targeted Protein Degradation from Physiological and Analytical Perspectives: Enabling Translation between Cells and Subjects von Daurio, Natalie A., Zhou, Haihong, Chen, Ying, Sheth, Payal R., Imbriglio, Jason E., McLaren, David G., Tawa, Paul, Rachdaoui, Nadia, Previs, Michael J., Kasumov, Takhar, O’Neil, Jennifer, Previs, Stephen F.

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Informing the Selection of Screening Hit Series with in Silico Absorption, Distribution, Metabolism, Excretion, and Toxicity Profiles von Sanders, John M, Beshore, Douglas C, Culberson, J Christopher, Fells, James I, Imbriglio, Jason E, Gunaydin, Hakan, Haidle, Andrew M, Labroli, Marc, Mattioni, Brian E, Sciammetta, Nunzio, Shipe, William D, Sheridan, Robert P, Suen, Linda M, Verras, Andreas, Walji, Abbas, Joshi, Elizabeth M, Bueters, Tjerk

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From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9 von Petrilli, Whitney L., Adam, Gregory C., Erdmann, Roman S., Abeywickrema, Pravien, Agnani, Vijayalakshmi, Ai, Xi, Baysarowich, Jen, Byrne, Noel, Caldwell, John P., Chang, Wonsuk, DiNunzio, Edward, Feng, Zhe, Ford, Rachael, Ha, Sookhee, Huang, Yongcheng, Hubbard, Brian, Johnston, Jennifer M., Kavana, Michael, Lisnock, Jean-Marie, Liang, Rui, Lu, Jun, Lu, Zhijian, Meng, Juncai, Orth, Peter, Palyha, Oksana, Parthasarathy, Gopal, Salowe, Scott P., Sharma, Sujata, Shipman, Jennifer, Soisson, Stephen M., Strack, AlisonM, Youm, Hyewon, Zhao, Kake, Zink, Deborah L., Zokian, Hratch, Addona, George H., Akinsanya, Karen, Tata, James R., Xiong, Yusheng, Imbriglio, Jason E.

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Discovery and Pharmacology of a Novel Class of Diacylglycerol Acyltransferase 2 Inhibitors von Imbriglio, Jason E, Shen, Dong-Ming, Liang, Rui, Marby, Ken, You, Ming, Youm, Hye Won, Feng, Zhe, London, Clare, Xiong, Yusheng, Tata, Jim, Verras, Andreas, Garcia-Calvo, Margarita, Song, Xuelei, Addona, George H, McLaren, Dave G, He, Timothy, Murphy, Beth, Metzger, Dan E, Salituro, Gino, Deckman, Diana, Chen, Qing, Jin, Xiaoling, Stout, Steven J, Wang, Sheng-Ping, Wilsie, Larissa, Palyha, Oksana, Han, Seongah, Hubbard, Brian K, Previs, Stephen F, Pinto, Shirly, Taggart, Andrew

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Amino acid-peptide-catalyzed enantioselective Morita–Baylis–Hillman reactions von Vasbinder, Melissa M., Imbriglio, Jason E., Miller, Scott J.

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A peptide-catalyzed asymmetric Stetter reaction von Mennen, Steven M, Blank, Jarred T, Tran-Dubé, Michelle B, Imbriglio, Jason E, Miller, Scott J

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Informing the Selection of Screening Hit Series with in Silico Absorption, Distribution, Metabolism, Excretion, and Toxicity Profiles: Miniperspective von Sanders, John M, Beshore, Douglas C, Culberson, J. Christopher, Fells, James I, Imbriglio, Jason E, Gunaydin, Hakan, Haidle, Andrew M, Labroli, Marc, Mattioni, Brian E, Sciammetta, Nunzio, Shipe, William D, Sheridan, Robert P, Suen, Linda M, Verras, Andreas, Walji, Abbas, Joshi, Elizabeth M, Bueters, Tjerk

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Identification of DGAT2 Inhibitors Using Mass Spectrometry von Song, Xuelei S., Zhang, Jiaping, Chen, Xun, Palyha, Oksana, Chung, Christine, Sonatore, Lisa M., Wilsie, Larissa, Stout, Steven, McLaren, David G., Taggart, Andrew, Imbriglio, Jason E., Pinto, Shirly, Garcia-Calvo, Margarita, Addona, George H.

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The Synthesis and Chemoselective Reactivity of 3-Aminocyclopentadienones von Rainier, Jon D, Imbriglio, Jason E

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The discovery of high affinity agonists of GPR109a with reduced serum shift and improved ADME properties von Imbriglio, Jason E., DiRocco, Daniel, Bodner, Rena, Raghavan, Subharekha, Chen, Weichun, Marley, Daria, Esser, Craig, Holt, Tom G., Wolff, Michael S., Taggart, Andrew K.P., Waters, M. Gerard, Tata, James R., Colletti, Steven L.

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GPR109a agonists. Part 1: 5-Alkyl and 5-aryl-pyrazole–tetrazoles as agonists of the human orphan G-protein coupled receptor GPR109a von Imbriglio, Jason E., Chang, Sookhee, Liang, Rui, Raghavan, Subharekha, Schmidt, Darby, Smenton, Abby, Tria, Scott, Schrader, Thomas O., Jung, Jae-Kyu, Esser, Craig, Taggart, Andrew K.P., Cheng, Kang, Carballo-Jane, Ester, Gerard Waters, M., Tata, James R., Colletti, Steven L.

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GPR109a agonists. Part 2: Pyrazole-acids as agonists of the human orphan G-protein coupled receptor GPR109a von Imbriglio, Jason E., Chang, Sookhee, Liang, Rui, Raghavan, Subharekha, Schmidt, Darby, Smenton, Abby, Tria, Scott, Schrader, Thomas O., Jung, Jae-Kyu, Esser, Craig, Holt, Tom G., Wolff, Michael S., Taggart, Andrew K.P., Cheng, Kang, Carballo-Jane, Ester, Waters, M. Gerard, Tata, James R., Colletti, Steven L.

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[2+2+1] Cycloadditions of ynol ethers. The synthesis of iron complexes of 3-alkoxycyclopentadienones von Imbriglio, Jason E, Rainier, Jon D

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The synthesis and conformational analysis of amino acid–tetrahydroanthranilic acid hybrids von Imbriglio, Jason E., DiRocco, Daniel, Raghavan, Subharekha, Ball, Richard G., Tsou, Nancy, Mosley, Ralph T., Tata, James R., Colletti, Steven L.

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