Purinergic and pyrimidinergic receptors as potential drug targets von Williams, Michael, Jarvis, Michael F

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Analgesic profile of intrathecal P2X(3) antisense oligonucleotide treatment in chronic inflammatory and neuropathic pain states in rats von Honore, Prisca, Kage, Karen, Mikusa, Joseph, Watt, Andrew T, Johnston, Joseph F, Wyatt, Jacqueline R, Faltynek, Connie R, Jarvis, Michael F, Lynch, Kevin

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Systemic and Site-Specific Effects of A-425619, a Selective TRPV1 Receptor Antagonist, on Wide Dynamic Range Neurons in CFA-Treated and Uninjured Rats von McGaraughty, Steve, Chu, Katharine L, Faltynek, Connie R, Jarvis, Michael F

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Therapeutic potential of adenosine kinase inhibitors von Kowaluk, Elizabeth A, Jarvis, Michael F

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P2X Receptor-Mediated Ionic Currents in Dorsal Root Ganglion Neurons von Burgard, Edward C, Niforatos, Wende, van Biesen, Tim, Lynch, Kevin J, Touma, Edward, Metzger, Randy E, Kowaluk, Elizabeth A, Jarvis, Michael F

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Distinct neurochemical mechanisms are activated following administration of different P2X receptor agonists into the hindpaw of a rat von Wismer, Carol T, Faltynek, Connie R, Jarvis, Michael F, McGaraughty, Steve

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ABT-627, an endothelin ETA receptor-selective antagonist, attenuates tactile allodynia in a diabetic rat model of neuropathic pain von JARVIS, M. F, WESSALE, J. L, ZHU, C. Z, LYNCH, J. J, DAYTON, B. D, CALZADILLA, S. V, PADLEY, R. J, OPGENORTH, T. J, KOWALUK, E. A

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A peripherally acting, selective T-type calcium channel blocker, ABT-639, effectively reduces nociceptive and neuropathic pain in rats von Jarvis, Michael F., Scott, Victoria E., McGaraughty, Steve, Chu, Katharine L., Xu, Jun, Niforatos, Wende, Milicic, Ivan, Joshi, Shailen, Zhang, Qingwei, Xia, Zhiren

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Purine and Pyrimidine (P2) Receptors as Drug Targets von Jacobson, Kenneth A, Jarvis, Michael F, Williams, Michael

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The effect of ABT‐702, a novel adenosine kinase inhibitor, on the responses of spinal neurones following carrageenan inflammation and peripheral nerve injury von Suzuki, Rie, Stanfa, Louise C, Kowaluk, Elizabeth A, Williams, Michael, Jarvis, Michael F, Dickenson, Anthony H

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Structure−Activity Relationship Studies on a Series of Novel, Substituted 1-Benzyl-5-phenyltetrazole P2X7 Antagonists von Nelson, Derek W, Gregg, Robert J, Kort, Michael E, Perez-Medrano, Arturo, Voight, Eric A, Wang, Ying, Grayson, George, Namovic, Marian T, Donnelly-Roberts, Diana L, Niforatos, Wende, Honore, Prisca, Jarvis, Michael F, Faltynek, Connie R, Carroll, William A

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A-134974: a novel adenosine kinase inhibitor, relieves tactile allodynia via spinal sites of action in peripheral nerve injured rats von Zhu, Chang Z, Mikusa, Joe, Chu, Katharine L, Cowart, Marlon, Kowaluk, Elizabeth A, Jarvis, Michael F, McGaraughty, Steve

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An adenosine kinase inhibitor attenuates tactile allodynia in a rat model of diabetic neuropathic pain von Lynch, James J, Jarvis, Michael F, Kowaluk, Elizabeth A

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Involvement of the TTX-resistant sodium channel Nav 1.8 in inflammatory and neuropathic, but not post-operative, pain states von Joshi, S.K., Mikusa, Joseph P., Hernandez, Gricelda, Baker, Scott, Shieh, Char-Chang, Neelands, Torben, Zhang, Xu-Feng, Niforatos, Wende, Kage, Karen, Han, Ping, Krafte, Douglas, Faltynek, Connie, Sullivan, James P., Jarvis, Michael F., Honore, Prisca

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Identification of (R)-1-(5-tert-Butyl-2,3-dihydro-1H-inden-1-yl)-3-(1H-indazol-4-yl)urea (ABT-102) as a Potent TRPV1 Antagonist for Pain Management von Gomtsyan, Arthur, Bayburt, Erol K, Schmidt, Robert G, Surowy, Carol S, Honore, Prisca, Marsh, Kennan C, Hannick, Steven M, McDonald, Heath A, Wetter, Jill M, Sullivan, James P, Jarvis, Michael F, Faltynek, Connie R, Lee, Chih-Hung

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Spinal microglial activation in rat models of neuropathic and osteoarthritic pain: An autoradiographic study using [3H]PK11195 von Miller, T.R., Wetter, J.B., Jarvis, M.F., Bitner, R.S.

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A mixed Ca2+ channel blocker, A-1264087, utilizes peripheral and spinal mechanisms to inhibit spinal nociceptive transmission in a rat model of neuropathic pain von Xu, Jun, Chu, Katharine L, Zhu, Chang Z, Niforatos, Wende, Swensen, Andrew, Searle, Xenia, Lee, Lance, Jarvis, Michael F, McGaraughty, Steve

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Novel Transient Receptor Potential Vanilloid 1 Receptor Antagonists for the Treatment of Pain:  Structure−Activity Relationships for Ureas with Quinoline, Isoquinoline, Quinazoline... von Gomtsyan, Arthur, Bayburt, Erol K, Schmidt, Robert G, Zheng, Guo Zhu, Perner, Richard J, Didomenico, Stanley, Koenig, John R, Turner, Sean, Jinkerson, Tammie, Drizin, Irene, Hannick, Steven M, Macri, Bryan S, McDonald, Heath A, Honore, Prisca, Wismer, Carol T, Marsh, Kennan C, Wetter, Jill, Stewart, Kent D, Oie, Tetsuro, Jarvis, Michael F, Surowy, Carol S, Faltynek, Connie R, Lee, Chih-Hung

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A-1048400 is a novel, orally active, state-dependent neuronal calcium channel blocker that produces dose-dependent antinociception without altering hemodynamic function in rats von Scott, Victoria E., Vortherms, Timothy A., Niforatos, Wende, Swensen, Andrew M., Neelands, Torben, Milicic, Ivan, Banfor, Patricia N., King, Andrew, Zhong, Chengmin, Simler, Gricelda, Zhan, Cenchen, Bratcher, Natalie, Boyce-Rustay, Janel M., Zhu, Chang Z., Bhatia, Pramila, Doherty, George, Mack, Helmut, Stewart, Andrew O., Jarvis, Michael F.

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Interleukin-1 alpha beta gene-deficient mice show reduced nociceptive sensitivity in models of inflammatory and neuropathic pain but not post-operative pain von Honore, P, Wade, CL, Zhong, C, Harris, R R, Wu, C, Ghayur, T, Iwakura, Y, Decker, M W, Faltynek, C, Sullivan, J, Jarvis, M F

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