‘Smart’ insulin-delivery technologies and intrinsic glucose-responsive insulin analogues von Jarosinski, Mark A., Dhayalan, Balamurugan, Rege, Nischay, Chatterjee, Deepak, Weiss, Michael A.

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New Horizons: Next-Generation Insulin Analogues: Structural Principles and Clinical Goals von Jarosinski, Mark A, Chen, Yen-Shan, Varas, Nicolás, Dhayalan, Balamurugan, Chatterjee, Deepak, Weiss, Michael A

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Structural principles of insulin formulation and analog design: A century of innovation von Jarosinski, Mark A., Dhayalan, Balamurugan, Chen, Yen-Shan, Chatterjee, Deepak, Varas, Nicolás, Weiss, Michael A.

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Insertion of a synthetic switch into insulin provides metabolite-dependent regulation of hormone–receptor activation von Chen, Yen-Shan, Gleaton, Jeremy, Yang, Yanwu, Dhayalan, Balamurugan, Phillips, Nelson B., Liu, Yule, Broadwater, Laurie, Jarosinski, Mark A., Chatterjee, Deepak, Lawrence, Michael C., Hattier, Thomas, Michael, M. Dodson, Weiss, Michael A.

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Peptide Model of the Mutant Proinsulin Syndrome. I. Design and Clinical Correlation von Dhayalan, Balamurugan, Glidden, Michael D, Zaykov, Alexander N, Chen, Yen-Shan, Yang, Yanwu, Phillips, Nelson B, Ismail-Beigi, Faramarz, Jarosinski, Mark A, DiMarchi, Richard D, Weiss, Michael A

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β-Secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACE von Vassar, Robert, Bennett, Brian D., Babu-Khan, Safura, Kahn, Steve, Mendiaz, Elizabeth A., Denis, Paul, Teplow, David B., Ross, Sandra, Amarante, Patricia, Loeloff, Richard, Luo, Yi, Fisher, Seth, Fuller, Janis, Edenson, Steven, Lile, Jackson, Jarosinski, Mark A., Biere, Anja Leona, Curran, Eileen, Burgess, Teresa, Louis, Jean-Claude, Collins, Frank, Treanor, James, Rogers, Gary, Citron, Martin

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Proteinase-activated receptor-2 mediates hyperresponsiveness in isolated guinea pig bronchi von Barrios, Victor E., Jarosinski, Mark A., Wright, Clifford D.

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Design of a new peptidomimetic agonist for the melanocortin receptors based on the solution structure of the peptide ligand, Ac-Nle-cyclo[Asp-Pro-DPhe-Arg-Trp-Lys]-NH2 von FOTSCH, Christopher, SMITH, Duncan M, TAMAYO, Nuria A, NING XI, BAUMGARTNER, James W, ADAMS, Jeffrey A, CHEETHAM, Janet, CROGHAN, Michael, DOHERTY, Elizabeth M, HALE, Clarence, JAROSINSKI, Mark A, KELLY, Michael G, NORMAN, Mark H

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Structural and Conformational Requirements for High-Affinity Binding to the SH2 Domain of Grb2 von Ettmayer, Peter, France, Dennis, Gounarides, John, Jarosinski, Mark, Martin, Mary-Sue, Rondeau, Jean-Michel, Sabio, Michael, Topiol, Sid, Weidmann, Beat, Zurini, Mauro, Bair, Kenneth W

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RF04 | PSUN233 Design of an Ultra-Stable Insulin/Glucagon Fusion Protein von Grabowski, Rachel, Ismail-Beigi, Faramarz, Jarosinski, Mark, Phillips, Nelson, Poordian, Shayan, Varas, Nicolas, Weiss, Michael

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Reassessment of an Innovative Insulin Analogue Excludes Protracted Action yet Highlights the Distinction between External and Internal Diselenide Bridges von Dhayalan, Balamurugan, Chen, Yen‐Shan, Phillips, Nelson B., Swain, Mamuni, Rege, Nischay K., Mirsalehi, Ali, Jarosinski, Mark, Ismail‐Beigi, Faramarz, Metanis, Norman, Weiss, Michael A.

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Rational, computer-enabled peptide drug design: principles, methods, applications and future directions von Diller, David J, Swanson, Jon, Bayden, Alexander S, Jarosinski, Mark, Audie, Joseph

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Inhibiting IL-2 Signaling and the Regulatory T-Cell Pathway Using Computationally Designed Novel Peptides von Price-Troska, Tammy, Diller, David, Bayden, Alexander, Jarosinski, Mark, Audies, Joseph, Yang, Zhi-Zhang, Ansell, Stephen M

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Characterization of the Stat5 Protease von Lee, Carolyn, Piazza, Flavia, Brutsaert, Siska, Valens, Jason, Strehlow, Inga, Jarosinski, Mark, Saris, Chris, Schindler, Christian

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Structure of a human DNA repair protein UBA domain that interacts with HIV-1 Vpr von Feigon, Juli, Dieckmann, Thorsten, Withers-Ward, Elizabeth S, Jarosinski, Mark A, Liu, Chuan-Fa, Chen, Irvin S. Y

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Inhibiting IL-2 signaling and the regulatory T-cell pathway using computationally designed peptides von Price-Troska, Tammy, Yang, Zhi-Zhang, Diller, David, Bayden, Alexander, Jarosinski, Mark, Audie, Joseph, Ansell, Stephen M.

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Insertion of a Synthetic Switch Into Insulin Provides Metabolite-Dependent Regulation of Hormone-Receptor Activation von Chen, Yen-Shan, Gleaton, Jeremy, Yang, Yanwu, Dhayalan, Balamurugan, Phillips, Nelson B, Liu, Yule, Broadwater, Laurie, Jarosinski, Mark, Chatterjee, Deepak, Lawrence, Michael C, Hattier, Thomas, Michael, Dodson M, Weiss, Michael Aaron

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Parkinson's Disease-associated α-Synuclein Is More Fibrillogenic than β- and γ-Synuclein and Cannot Cross-seed Its Homologs von Biere, Anja Leona, Wood, Stephen J., Wypych, Jette, Steavenson, Shirley, Jiang, Yijia, Anafi, Dan, Jacobsen, Frederick W., Jarosinski, Mark A., Wu, Gay-May, Louis, Jean-Claude, Martin, Francis, Narhi, Linda O., Citron, Martin

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Solid-Phase Synthesis via 5-Oxazolidinones. Ring-Opening Reactions with Amines and Reaction Monitoring by Single-Bead FT-IR Microspectroscopy von Marti, Roger E, Yan, Bing, Jarosinski, Mark A

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Synthesis, chemical reactivity, and antitumor evaluation of congeners of carmethizole hydrochloride, an experimental acylated vinylogous carbinolamine tumor inhibitor von Jarosinski, Mark A, Reddy, Peech S, Anderson, Wayne K

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