Development of autotaxin inhibitors: A series of zinc binding triazoles von Thomson, Christopher G., Le Grand, Darren, Dowling, Mark, Brocklehurst, Cara E., Chinn, Colin, Elphick, Lucy, Faller, Michael, Freeman, Mark, Furminger, Vikki, Gasser, Cornelia, Hamadi, Ahmed, Hardaker, Elizabeth, Head, Victoria, Hill, Johan C., Janus, Diana I., Pearce, David, Poulaud, Anne-Sophie, Stanley, Emily, Sviridenko, Lilya

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Synthesis of the Marine Sponge Derived β2-Adrenoceptor Agonist S1319 von Fairhurst, Robin A, Janus, Diana, Lawrence, Annabel

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The Identification of Indacaterol as an Ultralong-Acting Inhaled β2-Adrenoceptor Agonist von Baur, François, Beattie, David, Beer, David, Bentley, David, Bradley, Michelle, Bruce, Ian, Charlton, Steven J, Cuenoud, Bernard, Ernst, Roland, Fairhurst, Robin A, Faller, Bernard, Farr, David, Keller, Thomas, Fozard, John R, Fullerton, Joe, Garman, Sheila, Hatto, Julia, Hayden, Claire, He, Handan, Howes, Colin, Janus, Diana, Jiang, Zhengjin, Lewis, Christine, Loeuillet-Ritzler, Frederique, Moser, Heinz, Reilly, John, Steward, Alan, Sykes, David, Tedaldi, Lauren, Trifilieff, Alexandre, Tweed, Morris, Watson, Simon, Wissler, Elke, Wyss, Daniel

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The discovery of potent, orally bioavailable pyrimidine-5-carbonitrile-6-alkyl CXCR2 receptor antagonists von Porter, David W, Bradley, Michelle, Brown, Zarin, Charlton, Steven J, Cox, Brian, Hunt, Peter, Janus, Diana, Lewis, Sarah, Oakley, Paul, O'Connor, Des, Reilly, John, Smith, Nichola, Press, Neil J

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An investigation into the structure-activity relationships associated with the systematic modification of the β(2)-adrenoceptor agonist indacaterol von Beattie, David, Beer, David, Bradley, Michelle E, Bruce, Ian, Charlton, Steven J, Cuenoud, Bernard M, Fairhurst, Robin A, Farr, David, Fozard, John R, Janus, Diana, Rosethorne, Elizabeth M, Sandham, David A, Sykes, David A, Trifilieff, Alexandre, Turner, Katharine L, Wissler, Elke

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An investigation into the structure–activity relationships associated with the systematic modification of the β2-adrenoceptor agonist indacaterol von Beattie, David, Beer, David, Bradley, Michelle E., Bruce, Ian, Charlton, Steven J., Cuenoud, Bernard M., Fairhurst, Robin A., Farr, David, Fozard, John R., Janus, Diana, Rosethorne, Elizabeth M., Sandham, David A., Sykes, David A., Trifilieff, Alexandre, Turner, Katharine L., Wissler, Elke

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The identification of 7-[(R)-2-((1S,2S)-2-benzyloxycyclopentylamino)-1-hydroxyethyl]-4-hydroxybenzothiazolone as an inhaled long-acting β2-adrenoceptor agonist von Arnold, Nicola, Beattie, David, Bradley, Michelle, Brearley, Andrew, Brown, Lyndon, Charlton, Steven J., Fairhurst, Robin A., Farr, David, Fozard, John, Fullerton, Joe, Gosling, Martin, Hatto, Julia, Janus, Diana, Jones, Darryl, Jordan, Lynne, Lewis, Christine, Maas, Janet, McCarthy, Clive, Mercer, Mark, Oakman, Helen, Press, Neil, Profit, Rachel, Schuerch, Friedrich, Sykes, David, Taylor, Roger J., Trifilieff, Alexandre, Tuffnell, Andrew

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A physical properties based approach for the exploration of a 4-hydroxybenzothiazolone series of β2-adrenoceptor agonists as inhaled long-acting bronchodilators von BEATTIE, David, BRADLEY, Michelle, LEWIS, Christine, MCCARTHY, Clive, OAKMAN, Helen, STRINGER, Rowan, TAYLOR, Roger J, TUFFNELL, Andrew, BREARLEY, Andrew, CHARLTON, Steven J, CUENOUD, Bernard M, FAIRHURST, Robin A, GEDECK, Peter, GOSLING, Martin, JANUS, Diana, JONES, Darryl

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Synthesis of the marine sponge derived beta2-adrenoceptor agonist S1319 von Fairhurst, Robin A, Janus, Diana, Lawrence, Annabel

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An investigation into the structure-activity relationships associated with the systematic modification of the [beta]2-adrenoceptor agonist indacaterol von Beattie, David, Beer, David, Bradley, Michelle E, Bruce, Ian, Charlton, Steven J, Cuenoud, Bernard M, Fairhurst, Robin A, Farr, David, Fozard, John R, Janus, Diana, Rosethorne, Elizabeth M, Sandham, David A, Sykes, David A, Trifilieff, Alexandre, Turner, Katharine L, Wissler, Elke

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Synthesis of the Marine Sponge Derived β 2 -Adrenoceptor Agonist S1319 von Fairhurst, Robin A., Janus, Diana, Lawrence, Annabel

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Long-chain formoterol analogues: an investigation into the effect of increasing amino-substituent chain length on the β 2-adrenoceptor activity von Alikhani, Vahid, Beer, David, Bentley, David, Bruce, Ian, Cuenoud, Bernard M., Fairhurst, Robin A., Gedeck, Peter, Haberthuer, Sandra, Hayden, Claire, Janus, Diana, Jordan, Lynne, Lewis, Christine, Smithies, Kirsty, Wissler, Elke

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A physical properties based approach for the exploration of a 4-hydroxybenzothiazolone series of β 2-adrenoceptor agonists as inhaled long-acting bronchodilators von Beattie, David, Bradley, Michelle, Brearley, Andrew, Charlton, Steven J., Cuenoud, Bernard M., Fairhurst, Robin A., Gedeck, Peter, Gosling, Martin, Janus, Diana, Jones, Darryl, Lewis, Christine, McCarthy, Clive, Oakman, Helen, Stringer, Rowan, Taylor, Roger J., Tuffnell, Andrew

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The Identification of Indacaterol as an Ultralong-Acting Inhaled β 2 -Adrenoceptor Agonist von Baur, François, Beattie, David, Beer, David, Bentley, David, Bradley, Michelle, Bruce, Ian, Charlton, Steven J., Cuenoud, Bernard, Ernst, Roland, Fairhurst, Robin A., Faller, Bernard, Farr, David, Keller, Thomas, Fozard, John R., Fullerton, Joe, Garman, Sheila, Hatto, Julia, Hayden, Claire, He, Handan, Howes, Colin, Janus, Diana, Jiang, Zhengjin, Lewis, Christine, Loeuillet-Ritzler, Frederique, Moser, Heinz, Reilly, John, Steward, Alan, Sykes, David, Tedaldi, Lauren, Trifilieff, Alexandre, Tweed, Morris, Watson, Simon, Wissler, Elke, Wyss, Daniel

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A physical properties based approach for the exploration of a 4-hydroxybenzothiazolone series of beta2-adrenoceptor agonists as inhaled long-acting bronchodilators von Beattie, David, Bradley, Michelle, Brearley, Andrew, Charlton, Steven J, Cuenoud, Bernard M, Fairhurst, Robin A, Gedeck, Peter, Gosling, Martin, Janus, Diana, Jones, Darryl, Lewis, Christine, McCarthy, Clive, Oakman, Helen, Stringer, Rowan, Taylor, Roger J, Tuffnell, Andrew

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Long-chain formoterol analogues: an investigation into the effect of increasing amino-substituent chain length on the beta2-adrenoceptor activity von Alikhani, Vahid, Beer, David, Bentley, David, Bruce, Ian, Cuenoud, Bernard M, Fairhurst, Robin A, Gedeck, Peter, Haberthuer, Sandra, Hayden, Claire, Janus, Diana, Jordan, Lynne, Lewis, Christine, Smithies, Kirsty, Wissler, Elke

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Long-chain formoterol analogues: an investigation into the effect of increasing amino-substituent chain length on the β2-adrenoceptor activity von ALIKHANI, Vahid, BEER, David, JORDAN, Lynne, LEWIS, Christine, SMITHIES, Kirsty, WISSLER, Elke, BENTLEY, David, BRUCE, Ian, CUENOUD, Bernard M, FAIRHURST, Robin A, GEDECK, Peter, HABERTHUER, Sandra, HAYDEN, Claire, JANUS, Diana

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Design and Synthesis of Thrombin Inhibitors:  Analogues of MD-805 with Reduced Stereogenicity and Improved Potency von Brundish, Derek, Bull, Alice, Donovan, Vera, Fullerton, Joseph D, Garman, Sheila M, Hayler, Judy F, Janus, Diana, Kane, Peter D, McDonnell, Mark, Smith, Garrick P, Wakeford, Robert, Walker, Clive V, Howarth, Graham, Hoyle, William, Allen, Mark C, Ambler, John, Butler, Keith, Talbot, Mark D

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The identification of indacaterol as an ultralong-acting inhaled beta2-adrenoceptor agonist von Baur, François, Beattie, David, Beer, David, Bentley, David, Bradley, Michelle, Bruce, Ian, Charlton, Steven J, Cuenoud, Bernard, Ernst, Roland, Fairhurst, Robin A, Faller, Bernard, Farr, David, Keller, Thomas, Fozard, John R, Fullerton, Joe, Garman, Sheila, Hatto, Julia, Hayden, Claire, He, Handan, Howes, Colin, Janus, Diana, Jiang, Zhengjin, Lewis, Christine, Loeuillet-Ritzler, Frederique, Moser, Heinz, Reilly, John, Steward, Alan, Sykes, David, Tedaldi, Lauren, Trifilieff, Alexandre, Tweed, Morris, Watson, Simon, Wissler, Elke, Wyss, Daniel

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The Discovery of orally available thrombin inhibitors : Studies towards the optimisation of CGH1668 von Ambler, John, Baker, Emma, Brown, Lyndon, Butler, Paul, Farr, Dave, Dunnet, Karen, Grand, Darren Le, Janus, Diana, Jones, Darryl, Menear, Keith, Mercer, Mark, Smith, Garrick, Talbot, Mark, Tweed, Morris

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