A turquoise fluorescence lifetime-based biosensor for quantitative imaging of intracellular calcium von van der Linden, Franka H., Mahlandt, Eike K., Arts, Janine J. G., Beumer, Joep, Puschhof, Jens, de Man, Saskia M. A., Chertkova, Anna O., Ponsioen, Bas, Clevers, Hans, van Buul, Jaap D., Postma, Marten, Gadella, Theodorus W. J., Goedhart, Joachim

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Opto-RhoGEFs, an optimized optogenetic toolbox to reversibly control Rho GTPase activity on a global to subcellular scale, enabling precise control over vascular endothelial barrie... von Mahlandt, Eike K, Palacios Martínez, Sebastián, Arts, Janine J G, Tol, Simon, van Buul, Jaap D, Goedhart, Joachim

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Neutrophil transendothelial migration hotspots - mechanisms and implications von Grönloh, Max L B, Arts, Janine J G, van Buul, Jaap D

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Visualizing endogenous Rho activity with an improved localization-based, genetically encoded biosensor von Mahlandt, Eike K., Arts, Janine J. G., van der Meer, Werner J., van der Linden, Franka H., Tol, Simon, van Buul, Jaap D., Gadella, Theodorus W. J., Goedhart, Joachim

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Endothelial junctional membrane protrusions serve as hotspots for neutrophil transmigration von Arts, Janine JG, Mahlandt, Eike K, Grönloh, Max LB, Schimmel, Lilian, Noordstra, Ivar, Gordon, Emma, van Steen, Abraham CI, Tol, Simon, Walzog, Barbara, van Rijssel, Jos, Nolte, Martijn A, Postma, Marten, Khuon, Satya, Heddleston, John M, Wait, Eric, Chew, Teng Leong, Winter, Mark, Montanez, Eloi, Goedhart, Joachim, van Buul, Jaap D

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Endothelial transmigration hotspots limit vascular leakage through heterogeneous expression of ICAM‐1 von Grönloh, Max L B, Arts, Janine J G, Palacios Martínez, Sebastián, van der Veen, Amerens A, Kempers, Lanette, van Steen, Abraham C I, Roelofs, Joris J T H, Nolte, Martijn A, Goedhart, Joachim, van Buul, Jaap D

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Endothelial Focal Adhesions Are Functional Obstacles for Leukocytes During Basolateral Crawling von Arts, Janine J G, Mahlandt, Eike K, Schimmel, Lilian, Grönloh, Max L B, van der Niet, Sanne, Klein, Bart J A M, Fernandez-Borja, Mar, van Geemen, Daphne, Huveneers, Stephan, van Rijssel, Jos, Goedhart, Joachim, van Buul, Jaap D

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Leveraging premalignant biology for immune-based cancer prevention von Spira, Avrum, Disis, Mary L., Schiller, John T., Vilar, Eduardo, Rebbeck, Timothy R., Bejar, Rafael, Ideker, Trey, Arts, Janine, Yurgelun, Matthew B., Mesirov, Jill P., Rao, Anjana, Garber, Judy, Jaffee, Elizabeth M., Lippman, Scott M.

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The novel tryptamine derivative JNJ-26854165 induces wild-type p53- and E2F1-mediated apoptosis in acute myeloid and lymphoid leukemias von Kojima, Kensuke, Burks, Jared K, Arts, Janine, Andreeff, Michael

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JNJ-26481585, a Novel “Second-Generation” Oral Histone Deacetylase Inhibitor, Shows Broad-Spectrum Preclinical Antitumoral Activity von Arts, Janine, King, Peter, Mariën, Ann, Floren, Wim, Beliën, Ann, Janssen, Lut, Pilatte, Isabelle, Roux, Bruno, Decrane, Laurence, Gilissen, Ron, Hickson, Ian, Vreys, Veronique, Cox, Eugene, Bol, Kees, Talloen, Willem, Goris, Ilse, Andries, Luc, Du Jardin, Marc, Janicot, Michel, Page, Martin, van Emelen, Kristof, Angibaud, Patrick

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A novel experimental approach for the selective isolation and characterization of human RNase MRP von Derksen, Merel, Mertens, Vicky, Visser, Eline A., Arts, Janine, Vree Egberts, Wilma, Pruijn, Ger J. M.

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Mdm2 facilitates the association of p53 with the proteasome von Kulikov, Roman, Letienne, Justine, Kaur, Manjit, Grossman, Steven R, Arts, Janine, Blattner, Christine

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Preclinical anti‐myeloma activity of the novel HDAC‐inhibitor JNJ‐26481585 von Stühmer, Thorsten, Arts, Janine, Chatterjee, Manik, Borawski, Johanna, Wolff, André, King, Peter, Einsele, Hermann, Leo, Eugen, Bargou, Ralf C.

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Intercellular adhesion molecule 2 regulates diapedesis hotspots by allowing neutrophil crawling against the direction of flow von Grönloh, Max L B, Tebbens, Merel E, Kotsi, Marianthi, Arts, Janine J G, van Buul, Jaap D

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Primary adhered neutrophils increase JNK1-MARCKSL1-mediated filopodia to promote secondary neutrophil transmigration von Grönloh, Max Laurens Bastiaan, Arts, Janine Johanna Geertruida, Mahlandt, Eike Karin, Nolte, Martijn A., Goedhart, Joachim, van Buul, Jaap Diederik

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Microbiome confounders and quantitative profiling challenge predicted microbial targets in colorectal cancer development von Tito, Raúl Y., Verbandt, Sara, Aguirre Vazquez, Marta, Lahti, Leo, Verspecht, Chloe, Lloréns-Rico, Verónica, Vieira-Silva, Sara, Arts, Janine, Falony, Gwen, Dekker, Evelien, Reumers, Joke, Tejpar, Sabine, Raes, Jeroen

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Microbiome confounders and quantitative profiling challenge predicted microbial targets in colorectal cancer development von Tito, Raúl Y, Verbandt, Sara, Aguirre Vazquez, Marta, Lahti, Leo, Verspecht, Chloe, Lloréns-Rico, Verónica, Vieira-Silva, Sara, Arts, Janine, Falony, Gwen, Dekker, Evelien, Reumers, Joke, Tejpar, Sabine, Raes, Jeroen

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Microbiome confounders and quantitative profiling challengepredicted microbial targets in colorectal cancer development von Tito, Raúl Y, Verbandt, Sara, Aguirre Vazquez, Marta, Lahti, Leo, Verspecht, Chloe, Lloréns-Rico, Verónica, Vieira-Silva, Sara, Arts, Janine, Falony, Gwen, Dekker, Evelien, Reumers, Joke, Tejpar, Sabine, Raes, Jeroen

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Opto-RhoGEFs, an optimized optogenetic toolbox to reversibly control Rho GTPase activity on a global to subcellular scale, enabling precise control over vascular endothelial barrie... von Mahlandt, Eike K, Palacios Martínez, Sebastián, Arts, Janine JG, Tol, Simon, van Buul, Jaap D, Goedhart, Joachim

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Discovery of JNJ-88549968, a Novel, First-in-Class CALRmutxCD3 T-Cell Redirecting Antibody for the Treatment of Myeloproliferative Neoplasms von Kuchnio, Anna, Samakai, Elsie, Hug, Eva, Balmaña, Meritxell, Janssen, Lut, Amorim, Ricardo, Cornelissen, Ivo, Majoros, Andrea, Broux, Michaël, Taneja, Isha, Torti, Vince, Agic, Azra, Moritsch, Stefan, Benedetti, Filippo, Rosebrock, Felix, Packman, Kathryn, Arts, Janine, Patel, Sonal, Lomas, Oliver Christopher, Deyoung, M. Phillip, Zagrijtschuk, Oleh, Elsayed, Yusri, Constantinescu, Stefan, Kralovics, Robert, Philippar, Ulrike

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