Epigenetic silencing of BIM in glucocorticoid poor-responsive pediatric acute lymphoblastic leukemia, and its reversal by histone deacetylase inhibition von Bachmann, Petra S., Piazza, Rocco G., Janes, Mary E., Wong, Nicholas C., Davies, Carwyn, Mogavero, Angela, Bhadri, Vivek A., Szymanska, Barbara, Geninson, Greta, Magistroni, Vera, Cazzaniga, Giovanni, Biondi, Andrea, Miranda-Saavedra, Diego, Göttgens, Berthold, Saffery, Richard, Craig, Jeffrey M., Marshall, Glenn M., Gambacorti-Passerini, Carlo, Pimanda, John E., Lock, Richard B.

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Retinoic Acid Induces Pdx1-Positive Endoderm in Differentiating Mouse Embryonic Stem Cells von MICALLEF, Suzanne J, JANES, Mary E, KNEZEVIC, Kathy, DAVIS, Richard P, ELEFANTY, Andrew G, STANLEY, Edouard G

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A Runx1-Smad6 Rheostat Controls Runx1 Activity during Embryonic Hematopoiesis von Knezevic, Kathy, Bee, Thomas, Wilson, Nicola K., Janes, Mary E., Kinston, Sarah, Polderdijk, Stéphanie, Kolb-Kokocinski, Anja, Ottersbach, Katrin, Pencovich, Niv, Groner, Yoram, de Bruijn, Marella, Göttgens, Berthold, Pimanda, John E.

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Mapping and functional characterisation of a CTCF-dependent insulator element at the 3' border of the murine Scl transcriptional domain von Follows, George A, Ferreira, Rita, Janes, Mary E, Spensberger, Dominik, Cambuli, Francesco, Chaney, Amy F, Kinston, Sarah J, Landry, Josette R, Green, Anthony R, Göttgens, Berthold

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Endoglin expression in blood and endothelium is differentially regulated by modular assembly of the Ets/Gata hemangioblast code von Pimanda, John E., Chan, Wan Y.I., Wilson, Nicola K., Smith, Aileen M., Kinston, Sarah, Knezevic, Kathy, Janes, Mary E., Landry, Josette-Renée, Kolb-Kokocinski, Anja, Frampton, Jonathan, Tannahill, David, Ottersbach, Katrin, Follows, George A., Lacaud, Georges, Kouskoff, Valerie, Göttgens, Berthold

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Pdgfrα and Flk1 are direct target genes of Mixl1 in differentiating embryonic stem cells von Pereira, Lloyd A., Wong, Michael S., Mossman, Anna K., Sourris, Koula, Janes, Mary E., Knezevic, Kathy, Hirst, Claire E., Lim, Sue Mei, Pimanda, John E., Stanley, Edouard G., Elefanty, Andrew G.

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Real-time PCR mapping of DNaseI-hypersensitive sites using a novel ligation-mediated amplification technique von Follows, George A, Janes, Mary E, Vallier, Ludovic, Green, Anthony R, Gottgens, Berthold

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Identifying gene regulatory elements by genomic microarray mapping of DNaseI hypersensitive sites von Follows, George A, Dhami, Pawan, Göttgens, Berthold, Bruce, Alexander W, Campbell, Peter J, Dillon, Shane C, Smith, Aileen M, Koch, Christoph, Donaldson, Ian J, Scott, Mike A, Dunham, Ian, Janes, Mary E, Vetrie, David, Green, Anthony R

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Endocrine cells develop within pancreatic bud-like structures derived from mouse ES cells differentiated in response to BMP4 and retinoic acid von Micallef, Suzanne J., Li, Xueling, Janes, Mary E., Jackson, Steven A., Sutherland, Robyn M., Lew, Andrew M., Harrison, Leonard C., G. Elefanty, Andrew, Stanley, Edouard G.

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() The left-hand panels show the Sybr-green real-time PCR profiles (fluorescence versus cycle number) of 5-fold dilutions of quantified mouse genomic DNA standards for two primer p... von Follows, George A., Janes, Mary E., Vallier, Ludovic, Green, Anthony R., Göttgens, Berthold

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() Nuclei are isolated from cells, and aliquots are digested with a range of DNaseI as detailed in ‘Materials and methods’ section von Follows, George A., Janes, Mary E., Vallier, Ludovic, Green, Anthony R., Göttgens, Berthold

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The upper panel shows a Southern blot DHS map of the human STIL promoter in K562 cells using a 3′ probe (grey box labelled ‘P’) to analyse the BglII-restricted fragment (cut −4 kb... von Follows, George A., Janes, Mary E., Vallier, Ludovic, Green, Anthony R., Göttgens, Berthold

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Eph Receptors in the Immunosuppressive Tumor Microenvironment von Janes, Peter W, Vail, Mary E, Ernst, Matthias, Scott, Andrew M

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Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity von Meng, Bo, Abdullahi, Adam, Ferreira, Isabella A. T. M., Goonawardane, Niluka, Saito, Akatsuki, Kimura, Izumi, Yamasoba, Daichi, Gerber, Pehuén Pereyra, Fatihi, Saman, Rathore, Surabhi, Zepeda, Samantha K., Papa, Guido, Kemp, Steven A., Ikeda, Terumasa, Toyoda, Mako, Tan, Toong Seng, Kuramochi, Jin, Mitsunaga, Shigeki, Ueno, Takamasa, Shirakawa, Kotaro, Takaori-Kondo, Akifumi, Brevini, Teresa, Mallery, Donna L., Charles, Oscar J., Bowen, John E., Joshi, Anshu, Walls, Alexandra C., Jackson, Laurelle, Martin, Darren, Smith, Kenneth G. C., Bradley, John, Briggs, John A. G., Choi, Jinwook, Madissoon, Elo, Meyer, Kerstin B., Mlcochova, Petra, Ceron-Gutierrez, Lourdes, Doffinger, Rainer, Teichmann, Sarah A., Fisher, Andrew J., Pizzuto, Matteo S., de Marco, Anna, Corti, Davide, Hosmillo, Myra, Lee, Joo Hyeon, James, Leo C., Thukral, Lipi, Veesler, David, Sigal, Alex, Sampaziotis, Fotios, Goodfellow, Ian G., Matheson, Nicholas J., Sato, Kei, Gupta, Ravindra K.

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Deciphering the genomic, epigenomic, and transcriptomic landscapes of pre-invasive lung cancer lesions von Teixeira, Vitor H., Pipinikas, Christodoulos P., Pennycuick, Adam, Lee-Six, Henry, Chandrasekharan, Deepak, Beane, Jennifer, Morris, Tiffany J., Karpathakis, Anna, Feber, Andrew, Breeze, Charles E., Ntolios, Paschalis, Hynds, Robert E., Falzon, Mary, Capitanio, Arrigo, Carroll, Bernadette, Durrenberger, Pascal F., Hardavella, Georgia, Brown, James M., Lynch, Andy G., Farmery, Henry, Paul, Dirk S., Chambers, Rachel C., McGranahan, Nicholas, Navani, Neal, Thakrar, Ricky M., Swanton, Charles, Beck, Stephan, George, Phillip Jeremy, Spira, Avrum, Campbell, Peter J., Thirlwell, Christina, Janes, Sam M.

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Efficacy of the mRNA-1273 SARS-CoV-2 Vaccine at Completion of Blinded Phase von El Sahly, Hana M, Baden, Lindsey R, Essink, Brandon, Doblecki-Lewis, Susanne, Martin, Judith M, Anderson, Evan J, Campbell, Thomas B, Clark, Jesse, Jackson, Lisa A, Fichtenbaum, Carl J, Zervos, Marcus, Rankin, Bruce, Eder, Frank, Feldman, Gregory, Kennelly, Christina, Han-Conrad, Laurie, Levin, Michael, Neuzil, Kathleen M, Corey, Lawrence, Gilbert, Peter, Janes, Holly, Follmann, Dean, Marovich, Mary, Polakowski, Laura, Mascola, John R, Ledgerwood, Julie E, Graham, Barney S, August, Allison, Clouting, Heather, Deng, Weiping, Han, Shu, Leav, Brett, Manzo, Deb, Pajon, Rolando, Schödel, Florian, Tomassini, Joanne E, Zhou, Honghong, Miller, Jacqueline

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An activated form of ADAM10 is tumor selective and regulates cancer stem-like cells and tumor growth von Atapattu, Lakmali, Saha, Nayanendu, Chheang, Chanly, Eissman, Moritz F, Xu, Kai, Vail, Mary E, Hii, Linda, Llerena, Carmen, Liu, Zhanqi, Horvay, Katja, Abud, Helen E, Kusebauch, Ulrike, Moritz, Robert L, Ding, Bi-Sen, Cao, Zhongwei, Rafii, Shahin, Ernst, Matthias, Scott, Andrew M, Nikolov, Dimitar B, Lackmann, Martin, Janes, Peter W

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Neurologic Involvement in Children and Adolescents Hospitalized in the United States for COVID-19 or Multisystem Inflammatory Syndrome von LaRovere, Kerri L, Riggs, Becky J, Poussaint, Tina Y, Young, Cameron C, Newhams, Margaret M, Maamari, Mia, Walker, Tracie C, Singh, Aalok R, Dapul, Heda, Hobbs, Charlotte V, McLaughlin, Gwenn E, Son, Mary Beth F, Maddux, Aline B, Clouser, Katharine N, Rowan, Courtney M, McGuire, John K, Fitzgerald, Julie C, Gertz, Shira J, Shein, Steven L, Munoz, Alvaro Coronado, Thomas, Neal J, Irby, Katherine, Levy, Emily R, Staat, Mary A, Tenforde, Mark W, Feldstein, Leora R, Halasa, Natasha B, Giuliano, John S, Hall, Mark W, Kong, Michele, Carroll, Christopher L, Schuster, Jennifer E, Doymaz, Sule, Loftis, Laura L, Tarquinio, Keiko M, Babbitt, Christopher J, Nofziger, Ryan A, Kleinman, Lawrence C, Keenaghan, Michael A, Cvijanovich, Natalie Z, Spinella, Philip C, Hume, Janet R, Wellnitz, Kari, Mack, Elizabeth H, Michelson, Kelly N, Flori, Heidi R, Patel, Manish M, Randolph, Adrienne G

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Single-cell multi-omics analysis of the immune response in COVID-19 von Stephenson, Emily, Reynolds, Gary, Botting, Rachel A., Calero-Nieto, Fernando J., Morgan, Michael D., Tuong, Zewen Kelvin, Bach, Karsten, Sungnak, Waradon, Worlock, Kaylee B., Yoshida, Masahiro, Kumasaka, Natsuhiko, Kania, Katarzyna, Engelbert, Justin, Olabi, Bayanne, Spegarova, Jarmila Stremenova, Wilson, Nicola K., Mende, Nicole, Jardine, Laura, Gardner, Louis C. S., Goh, Issac, Horsfall, Dave, McGrath, Jim, Webb, Simone, Mather, Michael W., Lindeboom, Rik G. H., Dann, Emma, Huang, Ni, Polanski, Krzysztof, Prigmore, Elena, Gothe, Florian, Scott, Jonathan, Payne, Rebecca P., Baker, Kenneth F., Hanrath, Aidan T., Schim van der Loeff, Ina C. D., Barr, Andrew S., Sanchez-Gonzalez, Amada, Bergamaschi, Laura, Mescia, Federica, Barnes, Josephine L., Kilich, Eliz, de Wilton, Angus, Saigal, Anita, Saleh, Aarash, Janes, Sam M., Smith, Claire M., Gopee, Nusayhah, Wilson, Caroline, Coupland, Paul, Coxhead, Jonathan M., Kiselev, Vladimir Yu, van Dongen, Stijn, Bacardit, Jaume, King, Hamish W., Rostron, Anthony J., Simpson, A. John, Hambleton, Sophie, Laurenti, Elisa, Lyons, Paul A., Meyer, Kerstin B., Nikolić, Marko Z., Duncan, Christopher J. A., Smith, Kenneth G. C., Teichmann, Sarah A., Clatworthy, Menna R., Marioni, John C., Göttgens, Berthold, Haniffa, Muzlifah

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Efficacy Trial of a DNA/rAd5 HIV-1 Preventive Vaccine von Hammer, Scott M, Sobieszczyk, Magdalena E, Janes, Holly, Karuna, Shelly T, Mulligan, Mark J, Grove, Doug, Koblin, Beryl A, Buchbinder, Susan P, Keefer, Michael C, Tomaras, Georgia D, Frahm, Nicole, Hural, John, Anude, Chuka, Graham, Barney S, Enama, Mary E, Adams, Elizabeth, DeJesus, Edwin, Novak, Richard M, Frank, Ian, Bentley, Carter, Ramirez, Shelly, Fu, Rong, Koup, Richard A, Mascola, John R, Nabel, Gary J, Montefiori, David C, Kublin, James, McElrath, M. Juliana, Corey, Lawrence, Gilbert, Peter B

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