The central role of DNA damage in the ageing process von Schumacher, Björn, Pothof, Joris, Vijg, Jan, Hoeijmakers, Jan H. J.

Volltext

The DNA damage response to transcription stress von Lans, Hannes, Hoeijmakers, Jan H. J., Vermeulen, Wim, Marteijn, Jurgen A.

Volltext

Cellular senescence drives age-dependent hepatic steatosis von Ogrodnik, Mikolaj, Miwa, Satomi, Tchkonia, Tamar, Tiniakos, Dina, Wilson, Caroline L., Lahat, Albert, Day, Christoper P., Burt, Alastair, Palmer, Allyson, Anstee, Quentin M., Grellscheid, Sushma Nagaraja, Hoeijmakers, Jan H J., Barnhoorn, Sander, Mann, Derek A., Bird, Thomas G., Vermeij, Wilbert P., Kirkland, James L., Passos, João F., von Zglinicki, Thomas, Jurk, Diana

Volltext

Understanding nucleotide excision repair and its roles in cancer and ageing von Marteijn, Jurgen A., Lans, Hannes, Vermeulen, Wim, Hoeijmakers, Jan H. J.

Volltext

Nuclear Genomic Instability and Aging von Niedernhofer, Laura J, Gurkar, Aditi U, Wang, Yinsheng, Vijg, Jan, Hoeijmakers, Jan H.J, Robbins, Paul D

Volltext

Genome maintenance mechanisms for preventing cancer von Hoeijmakers, Jan H. J

Volltext

A novel pulse-modulated closed-loop artificial pancreas based on intravenous administration of insulin and glucagon von Goede, Simon L., Snels, Victor H., Berghuis, Willem-Jan W. J. H., Bernards, Jan P. C., Wyder, Urs

Volltext

A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis von Robinson, Andria Rasile, Appeldoorn, Esther, Hoeijmakers, Jan H. J, Theil, Arjan F, Raams, Anja, Odijk, Hanny, Kleijer, Wim J, Meinecke, Peter, van Leeuwen, Wibeke, Lalai, Astrid S, Ahmad, Anwaar, Niedernhofer, Laura J, Vijg, Jan, Jaspers, Nicolaas G. J, Garinis, George A, Vermeulen, Wim, van der Horst, Gijsbertus T. J, Oostendorp, Roos

Volltext

Nodal promotes growth and invasion in human gliomas von Lee, C-C, Jan, H-J, Lai, J-H, Ma, H-I, Hueng, D-Y, Gladys Lee, Y-C, Cheng, Y-Y, Liu, L-W, Wei, H-W, Lee, H-M

Volltext

Genome Integrity in Aging: Human Syndromes, Mouse Models, and Therapeutic Options von Vermeij, Wilbert P, Hoeijmakers, Jan H.J, Pothof, Joris

Volltext

Deficiency in the DNA repair protein ERCC1 triggers a link between senescence and apoptosis in human fibroblasts and mouse skin von Kim, Dong Eun, Dollé, Martijn E. T., Vermeij, Wilbert P., Gyenis, Akos, Vogel, Katharina, Hoeijmakers, Jan H. J., Wiley, Christopher D., Davalos, Albert R., Hasty, Paul, Desprez, Pierre‐Yves, Campisi, Judith

Volltext

Age to survive: DNA damage and aging von Schumacher, Björn, Garinis, George A, Hoeijmakers, Jan H.J

Volltext

UV-sensitive syndrome protein UVSSA recruits USP7 to regulate transcription-coupled repair von Schwertman, Petra, Lagarou, Anna, Dekkers, Dick H W, Raams, Anja, van der Hoek, Adriana C, Laffeber, Charlie, Hoeijmakers, Jan H J, Demmers, Jeroen A A, Fousteri, Maria, Vermeulen, Wim, Marteijn, Jurgen A

Volltext

Joint analysis of stressors and ecosystem services to enhance restoration effectiveness von Allan, J. David, McIntyre, Peter B., Smith, Sigrid D. P., Halpern, Benjamin S., Boyer, Gregory L., Buchsbaum, Andy, Burton, G. A., Campbell, Linda M., Chadderton, W. Lindsay, Ciborowski, Jan J. H., Doran, Patrick J., Eder, Tim, Infante, Dana M., Johnson, Lucinda B., Joseph, Christine A., Marino, Adrienne L., Prusevich, Alexander, Read, Jennifer G., Rose, Joan B., Rutherford, Edward S., Sowa, Scott P., Steinman, Alan D.

Volltext

Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forks von Motegi, Akira, Liaw, Hung-Jiun, Lee, Kyoo-Young, Roest, Henk P, Maas, Alex, Wu, Xiaoli, Moinova, Helen, Markowitz, Sanford D, Ding, Hao, Hoeijmakers, Jan H.J, Myung, Kyungjae

Volltext

Base editor repairs mutation found in the premature-ageing syndrome progeria von Vermeij, Wilbert P., Hoeijmakers, Jan H. J.

Volltext

ERCC1-XPF Endonuclease Facilitates DNA Double-Strand Break Repair von Ahmad, Anwaar, Robinson, Andria Rasile, Duensing, Anette, van Drunen, Ellen, Beverloo, H. Berna, Weisberg, David B., Hasty, Paul, Hoeijmakers, Jan H. J., Niedernhofer, Laura J.

Volltext

The small CRL4CSA ubiquitin ligase component DDA1 regulates transcription-coupled repair dynamics von Llerena Schiffmacher, Diana A., Lee, Shun-Hsiao, Kliza, Katarzyna W., Theil, Arjan F., Akita, Masaki, Helfricht, Angela, Bezstarosti, Karel, Gonzalo-Hansen, Camila, van Attikum, Haico, Verlaan-de Vries, Matty, Vertegaal, Alfred C. O., Hoeijmakers, Jan H. J., Marteijn, Jurgen A., Lans, Hannes, Demmers, Jeroen A. A., Vermeulen, Michiel, Sixma, Titia K., Ogi, Tomoo, Vermeulen, Wim, Pines, Alex

Volltext

Rbm3 deficiency leads to transcriptome-wide splicing alterations von Erkelenz, Steffen, Grzonka, Marta, Papadakis, Antonios, Schaal, Heiner, Hoeijmakers, Jan H. J., Gyenis, Ákos

Volltext

DNA damage and transcription stress cause ATP-mediated redesign of metabolism and potentiation of anti-oxidant buffering von Milanese, Chiara, Bombardieri, Cíntia R., Sepe, Sara, Barnhoorn, Sander, Payán-Goméz, César, Caruso, Donatella, Audano, Matteo, Pedretti, Silvia, Vermeij, Wilbert P., Brandt, Renata M. C., Gyenis, Akos, Wamelink, Mirjam M., de Wit, Annelieke S., Janssens, Roel C., Leen, René, van Kuilenburg, André B. P., Mitro, Nico, Hoeijmakers, Jan H. J., Mastroberardino, Pier G.

Volltext