Phase 3 Trial of Transplantation of Human Islets in Type 1 Diabetes Complicated by Severe Hypoglycemia von Hering, Bernhard J, Clarke, William R, Bridges, Nancy D, Eggerman, Thomas L, Alejandro, Rodolfo, Bellin, Melena D, Chaloner, Kathryn, Czarniecki, Christine W, Goldstein, Julia S, Hunsicker, Lawrence G, Kaufman, Dixon B, Korsgren, Olle, Larsen, Christian P, Luo, Xunrong, Markmann, James F, Naji, Ali, Oberholzer, Jose, Posselt, Andrew M, Rickels, Michael R, Ricordi, Camillo, Robien, Mark A, Senior, Peter A, Shapiro, A M James, Stock, Peter G, Turgeon, Nicole A

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Phase 3 trial of human islet‐after‐kidney transplantation in type 1 diabetes von Markmann, James F., Rickels, Michael R., Eggerman, Thomas L., Bridges, Nancy D., Lafontant, David E., Qidwai, Julie, Foster, Eric, Clarke, William R., Kamoun, Malek, Alejandro, Rodolfo, Bellin, Melena D., Chaloner, Kathryn, Czarniecki, Christine W., Goldstein, Julia S., Hering, Bernhard J., Hunsicker, Lawrence G., Kaufman, Dixon B., Korsgren, Olle, Larsen, Christian P., Luo, Xunrong, Naji, Ali, Oberholzer, José, Posselt, Andrew M., Ricordi, Camillo, Senior, Peter A., Shapiro, A. M. James, Stock, Peter G., Turgeon, Nicole A.

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National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities von Ricordi, Camillo, Goldstein, Julia S, Balamurugan, A N, Szot, Gregory L, Kin, Tatsuya, Liu, Chengyang, Czarniecki, Christine W, Barbaro, Barbara, Bridges, Nancy D, Cano, Jose, Clarke, William R, Eggerman, Thomas L, Hunsicker, Lawrence G, Kaufman, Dixon B, Khan, Aisha, Lafontant, David-Erick, Linetsky, Elina, Luo, Xunrong, Markmann, James F, Naji, Ali, Korsgren, Olle, Oberholzer, Jose, Turgeon, Nicole A, Brandhorst, Daniel, Chen, Xiaojuan, Friberg, Andrew S, Lei, Ji, Wang, Ling-Jia, Wilhelm, Joshua J, Willits, Jamie, Zhang, Xiaomin, Hering, Bernhard J, Posselt, Andrew M, Stock, Peter G, Shapiro, A M James, Chen, Xiaojuan

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The caspase inhibitor IDN-6556 (PF3491390) improves marginal mass engraftment after islet transplantation in mice von McCall, Michael, MD, Toso, Christian, MD, PhD, Emamaullee, Juliet, MD, PhD, Pawlick, Rena, BSc, Edgar, Ryan, BSc, Davis, Joy, Maciver, Allison, MD, Kin, Tatsuya, MD, PhD, Arch, Robert, PhD, Shapiro, A.M. James, MD, PhD

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Inhibition of Th17 Cells Regulates Autoimmune Diabetes in NOD Mice von EMAMAULLEE, Juliet A, DAVIS, Joy, MERANI, Shaheed, TOSO, Christian, ELLIOTT, John F, THIESEN, Aducio, SHAPIRO, A. M. James

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Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic islets von Fu, Accalia, van Rooyen, Lara, Evans, Lindsay, Armstrong, Nina, Avizonis, Daina, Kin, Tatsuya, Bird, Gregory H., Reddy, Anita, Chouchani, Edward T., Liesa-Roig, Marc, Walensky, Loren D., Shapiro, A.M. James, Danial, Nika N.

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Beta Cell Death by Cell-free DNA and Outcome After Clinical Islet Transplantation von Gala-Lopez, Boris L, Neiman, Daniel, Kin, Tatsuya, O’Gorman, Doug, Pepper, Andrew R, Malcolm, Andrew J, Pianzin, Sheina, Senior, Peter A, Campbell, Patricia, Glaser, Benjamin, Dor, Yuval, Shemer, Ruth, Shapiro, A.M James

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Improvement in Outcomes of Clinical Islet Transplantation: 1999-2010 von BARTON, Franca B, RICKELS, Michael R, PATTOU, Francois, BERNEY, Thierry, SECCHI, Antonio, MESSINGER, Shari, SENIOR, Peter A, MAFFI, Paola, POSSELT, Andrew, STOCK, Peter G, KAUFMAN, Dixon B, XUNRONG LUO, ALEJANDRO, Rodolfo, KANDEEL, Fouad, CAGLIERO, Enrico, TURGEON, Nicole A, WITKOWSKI, Piotr, NAJI, Ali, O'CONNELL, Philip J, GREENBAUM, Carla, KUDVA, Yogish C, BRAYMAN, Kenneth L, AULL, Meredith J, HERING, Bernhard J, LARSEN, Christian, KAY, Tom W. H, FERNANDEZ, Luis A, VANTYGHEM, Marie-Christine, BELLIN, Melena, SHAPIRO, A. M. James, WEASE, Stephen, NAZIRUDDIN, Bashoo, OBERHOLZER, Jose, ODORICO, Jon S, GARFINKEL, Marc R, LEVY, Marlon

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Gearing Up for Stem Cell-derived Beta Cells—Are We Ready? von Shapiro, A.M James

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International Trial of the Edmonton Protocol for Islet Transplantation von Shapiro, A.M. James, Ricordi, Camillo, Hering, Bernhard J, Auchincloss, Hugh, Lindblad, Robert, Robertson, R. Paul, Secchi, Antonio, Brendel, Mathias D, Berney, Thierry, Brennan, Daniel C, Cagliero, Enrico, Alejandro, Rodolfo, Ryan, Edmond A, DiMercurio, Barbara, Morel, Philippe, Polonsky, Kenneth S, Reems, Jo-Anna, Bretzel, Reinhard G, Bertuzzi, Federico, Froud, Tatiana, Kandaswamy, Raja, Sutherland, David E.R, Eisenbarth, George, Segal, Miriam, Preiksaitis, Jutta, Korbutt, Gregory S, Barton, Franca B, Viviano, Lisa, Seyfert-Margolis, Vicki, Bluestone, Jeffrey, Lakey, Jonathan R.T

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Determination of Minimal Hemoglobin Level Necessary for Normothermic Porcine Ex situ Liver Perfusion von Bral, Mariusz, Gala-Lopez, Boris, Thiesen, Aducio, Hatami, Sanaz, Bigam, David L, Freed, Darren M, Shapiro, A.M James

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Five-Year Follow-Up After Clinical Islet Transplantation von RYAN, Edmond A, PATY, Breay W, SENIOR, Peter A, BIGAM, David, ALFADHLI, Eman, KNETEMAN, Norman M, LAKEY, Jonathan R. T, SHAPIRO, A. M

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Islet transplantation in type 1 diabetes: ongoing challenges, refined procedures, and long-term outcome von Shapiro, A M James

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Engraftment Site and Effectiveness of the Pan-Caspase Inhibitor F573 to Improve Engraftment in Mouse and Human Islet Transplantation in Mice von Pepper, Andrew R, Bruni, Antonio, Pawlick, Rena, Wink, John, Rafiei, Yasmin, Gala-Lopez, Boris, Bral, Mariusz, Abualhassan, Nasser, Kin, Tatsuya, Shapiro, A.M James

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Single-Donor Islet Transplantation and Long-term Insulin Independence in Select Patients With Type 1 Diabetes Mellitus von Al-Adra, David P, Gill, Richdeep S, Imes, Sharleen, O’Gorman, Doug, Kin, Tatsuya, Axford, Sara J, Shi, Xinzhe, Senior, Peter A, Shapiro, A.M James

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Intra-abdominal adhesions: Cellular mechanisms and strategies for prevention von Maciver, Allison H, McCall, Michael, James Shapiro, A.M

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Type 1 Diabetes Mellitus: Cellular and Molecular Pathophysiology at A Glance von Saberzadeh-Ardestani, Bahar, Karamzadeh, Razieh, Basiri, Mohsen, Hajizadeh-Saffar, Ensiyeh, Farhadi, Aisan, Shapiro, A M J, Tahamtani, Yaser, Baharvand, Hossein

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Clinical Magnetic Resonance Imaging of Pancreatic Islet Grafts After Iron Nanoparticle Labeling von Toso, C., Vallee, J.‐P., Morel, P., Ris, F., Demuylder‐Mischler, S., Lepetit‐Coiffe, M., Marangon, N., Saudek, F., James Shapiro, A. M., Bosco, D., Berney, T.

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Transplantation of Human Pancreatic Endoderm Cells Reverses Diabetes Post Transplantation in a Prevascularized Subcutaneous Site von Pepper, Andrew R., Pawlick, Rena, Bruni, Antonio, Wink, John, Rafiei, Yasmin, O’Gorman, Doug, Yan-Do, Richard, Gala-Lopez, Boris, Kin, Tatsuya, MacDonald, Patrick E., Shapiro, A.M. James

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E2F1 transcription factor mediates a link between fat and islets to promote β cell proliferation in response to acute insulin resistance von Shirakawa, Jun, Togashi, Yu, Basile, Giorgio, Okuyama, Tomoko, Inoue, Ryota, Fernandez, Megan, Kyohara, Mayu, De Jesus, Dario F., Goto, Nozomi, Zhang, Wei, Tsuno, Takahiro, Kin, Tatsuya, Pan, Hui, Dreyfuss, Jonathan M., Shapiro, A.M. James, Yi, Peng, Terauchi, Yasuo, Kulkarni, Rohit N.

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