The JAK-STAT pathway at 30: Much learned, much more to do von Philips, Rachael L., Wang, Yuxin, Cheon, HyeonJoo, Kanno, Yuka, Gadina, Massimo, Sartorelli, Vittorio, Horvath, Curt M., Darnell, James E., Stark, George R., O’Shea, John J.

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Pulmonary Arterial Enlargement and Acute Exacerbations of COPD von Wells, J. Michael, Washko, George R, Han, MeiLan K, Abbas, Naseer, Nath, Hrudaya, Mamary, A. James, Regan, Elizabeth, Bailey, William C, Martinez, Fernando J, Westfall, Elizabeth, Beaty, Terri H, Curran-Everett, Douglas, Curtis, Jeffrey L, Hokanson, John E, Lynch, David A, Make, Barry J, Crapo, James D, Silverman, Edwin K, Bowler, Russell P, Dransfield, Mark T

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ENGINE von JAMES J. E. PHILIPS

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A Pharmacogenetic versus a Clinical Algorithm for Warfarin Dosing von Kimmel, Stephen E, French, Benjamin, Kasner, Scott E, Johnson, Julie A, Anderson, Jeffrey L, Gage, Brian F, Rosenberg, Yves D, Eby, Charles S, Madigan, Rosemary A, McBane, Robert B, Abdel-Rahman, Sherif Z, Stevens, Scott M, Yale, Steven, Mohler, Emile R, Fang, Margaret C, Shah, Vinay, Horenstein, Richard B, Limdi, Nita A, Muldowney, James A.S, Gujral, Jaspal, Delafontaine, Patrice, Desnick, Robert J, Ortel, Thomas L, Billett, Henny H, Pendleton, Robert C, Geller, Nancy L, Halperin, Jonathan L, Goldhaber, Samuel Z, Caldwell, Michael D, Califf, Robert M, Ellenberg, Jonas H

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Amiodarone, Lidocaine, or Placebo in Out-of-Hospital Cardiac Arrest von Kudenchuk, Peter J, Brown, Siobhan P, Daya, Mohamud, Rea, Thomas, Nichol, Graham, Morrison, Laurie J, Leroux, Brian, Vaillancourt, Christian, Wittwer, Lynn, Callaway, Clifton W, Christenson, James, Egan, Debra, Ornato, Joseph P, Weisfeldt, Myron L, Stiell, Ian G, Idris, Ahamed H, Aufderheide, Tom P, Dunford, James V, Colella, M. Riccardo, Vilke, Gary M, Brienza, Ashley M, Desvigne-Nickens, Patrice, Gray, Pamela C, Gray, Randal, Seals, Norman, Straight, Ron, Dorian, Paul

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Phase 2 Placebo-Controlled Trial of Two Vaccines to Prevent Ebola in Liberia von Kennedy, Stephen B, Bolay, Fatorma, Kieh, Mark, Grandits, Greg, Badio, Moses, Ballou, Ripley, Eckes, Risa, Feinberg, Mark, Follmann, Dean, Grund, Birgit, Gupta, Swati, Hensley, Lisa, Higgs, Elizabeth, Janosko, Krisztina, Johnson, Melvin, Kateh, Francis, Logue, James, Marchand, Jonathan, Monath, Thomas, Nason, Martha, Nyenswah, Tolbert, Roman, François, Stavale, Eric, Wolfson, Julian, Neaton, James D, Lane, H. Clifford

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Antiretroviral Prophylaxis for HIV Prevention in Heterosexual Men and Women von Baeten, Jared M, Donnell, Deborah, Ndase, Patrick, Mugo, Nelly R, Campbell, James D, Wangisi, Jonathan, Tappero, Jordan W, Bukusi, Elizabeth A, Cohen, Craig R, Katabira, Elly, Ronald, Allan, Tumwesigye, Elioda, Were, Edwin, Fife, Kenneth H, Kiarie, James, Farquhar, Carey, John-Stewart, Grace, Kakia, Aloysious, Odoyo, Josephine, Mucunguzi, Akasiima, Nakku-Joloba, Edith, Twesigye, Rogers, Ngure, Kenneth, Apaka, Cosmas, Tamooh, Harrison, Gabona, Fridah, Mujugira, Andrew, Panteleeff, Dana, Thomas, Katherine K, Kidoguchi, Lara, Krows, Meighan, Revall, Jennifer, Morrison, Susan, Haugen, Harald, Emmanuel-Ogier, Mira, Ondrejcek, Lisa, Coombs, Robert W, Frenkel, Lisa, Hendrix, Craig, Bumpus, Namandjé N, Bangsberg, David, Haberer, Jessica E, Stevens, Wendy S, Lingappa, Jairam R, Celum, Connie

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COVID-19-associated risks and effects in myasthenia gravis (CARE-MG) von Muppidi, Srikanth, Guptill, Jeffrey T, Jacob, Saiju, Li, Yingkai, Farrugia, Maria E, Guidon, Amanda C, Tavee, Jinny O, Kaminski, Henry, Howard, James F, Cutter, Gary, Wiendl, Heinz, Maas, Matthew B, Illa, Isabel, Mantegazza, Renato, Murai, Hiroyuki, Utsugisawa, Kimiaki, Nowak, Richard J, Guidon, Amanda C, Tyagi, Alok, Sousa, Ana Paula, Amato, Anthony A, Pinto, Ashwin, Roy, Bhaskar, Carmichael, Caroline, Dodig, Dubravka, Burke, Georgina, Cutter, Gary R, Kaminski, Henry J, Wiendl, Heinz, Murai, Hiroyuki, Lee, Ikjae, Illa, Isabel, Guptill, Jeffrey, Howard, James F., Caress, James, Pritchard, Jane, Tavee, Jinny O, Vissing, John, Best, Kamla, Utsugisawa, Kimiaki, Ramezani, Mahtab, Maas, Mathew, Farrugia, Maria E, Hehir, Michael K, Kaku, Michelle, Esquivel, Natalia Jiménez, Gallagher, Paul, Maddison, Paul, Ambrose, Philip A, Mantegazza, Renato E, Nowak, Richard J, Do Campo, Rocio Vazquez, Jacob, Saiju, Saba, Sami, Nafissi, Shahriar, Itoyama, Shannon, Muppidi, Srikanth, Viegas, Stuart Viegas, Marshall, Victoria, Li, Yingkai Li

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Blood Pressure in Early Autosomal Dominant Polycystic Kidney Disease von Schrier, Robert W, Abebe, Kaleab Z, Perrone, Ronald D, Torres, Vicente E, Braun, William E, Steinman, Theodore I, Winklhofer, Franz T, Brosnahan, Godela, Czarnecki, Peter G, Hogan, Marie C, Miskulin, Dana C, Rahbari-Oskoui, Frederic F, Grantham, Jared J, Harris, Peter C, Flessner, Michael F, Bae, Kyongtae T, Moore, Charity G, Chapman, Arlene B

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Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders von Tucker-Drob, Elliot M., Yu, Dongmei, Ge, Tian, Derks, Eske M., Keski-Rahkonen, Anna, Kirov, George, Asherson, Philip, Baldursson, Gísli, Bybjerg-Grauholm, Jonas, Churchhouse, Claire, Crosbie, Jennifer, Demontis, Ditte, Grove, Jakob, Martin, Joanna, McGough, James J., Pedersen, Carsten B., Poulsen, Jesper B., Rothenberger, Aribert, Schachar, Russell, Turley, Patrick, Arking, Dan E., Collins, Ryan L., Coon, Hilary, Delorme, Richard, Hope, Sigrun, Nyegaard, Mette, Pinto, Dalila, Qvist, Per, Talkowski, Michael E., Albani, Diego, Alda, Martin, Bass, Nicholas, Bauer, Michael, Cichon, Sven, Clarke, Toni-Kim, Czerski, Piotr M., Fischer, Sascha B., Frank, Josef, Goes, Fernando S., Holland, Dominic, Jones, Lisa A., Joachim, Oedegaard Ketil, Maaser, Anna, Malt, Ulrik F., McMahon, Francis J., Montgomery, Grant W., Myers, Richard M., Nöthen, Markus M., Perry, Amy, Vieta, Eduard, Aschauer, Harald, Bencko, Vladimir, Burghardt, Roland, Carlberg, Laura, Guo, Yiran, Klump, Kelly L., Le Hellard, Stephanie, Monteleone, Alessio Maria, Seitz, Jochen, Treasure, Janet, Wade, Tracey D., Wichmann, H-Erich, Woodside, D. Blake, Grabe, Hans J., Horn, Carsten, Penninx, Brenda WJH, Schulte, Eva C., Smith, Daniel J., Alexander, Madeline, Begemann, Martin, Campion, Dominique, Ehrenreich, Hannelore, Murphy, Kieran C., Riley, Brien, Sham, Pak C., van Os, Jim, Weiser, Mark, Brown, Lawrence W., Cheon, Keun-Ah, Denys, Damiaan, Gilbert, Donald L., Grados, Marco A., Ibanez-Gomez, Laura, King, Robert A., Leventhal, Bennett L., Okun, Michael S., Piras, Federica, Robertson, Mary, Samuels, Jack F., Spalletta, Gianfranco, Stein, Dan J., Stewart, S Evelyn, Storch, Eric A., Stranger, Barbara, Tübing, Jennifer, Visscher, Frank, Wagner, Michael, Santangelo, Susan L., Thornton, Laura M., Neale, Benjamin M.

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Elexacaftor–Tezacaftor–Ivacaftor for Cystic Fibrosis with a Single Phe508del Allele von Middleton, Peter G, Mall, Marcus A, Dřevínek, Pavel, Lands, Larry C, McKone, Edward F, Polineni, Deepika, Ramsey, Bonnie W, Taylor-Cousar, Jennifer L, Tullis, Elizabeth, Vermeulen, François, Marigowda, Gautham, McKee, Charlotte M, Moskowitz, Samuel M, Nair, Nitin, Savage, Jessica, Simard, Christopher, Tian, Simon, Waltz, David, Xuan, Fengjuan, Rowe, Steven M, Jain, Raksha

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Angiotensin Blockade in Late Autosomal Dominant Polycystic Kidney Disease von Torres, Vicente E, Abebe, Kaleab Z, Chapman, Arlene B, Schrier, Robert W, Braun, William E, Steinman, Theodore I, Winklhofer, Franz T, Brosnahan, Godela, Czarnecki, Peter G, Hogan, Marie C, Miskulin, Dana C, Rahbari-Oskoui, Frederic F, Grantham, Jared J, Harris, Peter C, Flessner, Michael F, Moore, Charity G, Perrone, Ronald D

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Antibody decay, T cell immunity and breakthrough infections following two SARS-CoV-2 vaccine doses in inflammatory bowel disease patients treated with infliximab and vedolizumab von Lin, Simeng, Kennedy, Nicholas A., Saifuddin, Aamir, Sandoval, Diana Muñoz, Reynolds, Catherine J., Seoane, Rocio Castro, Kottoor, Sherine H., Pieper, Franziska P., Lin, Kai-Min, Butler, David K., Chanchlani, Neil, Nice, Rachel, Chee, Desmond, Bewshea, Claire, Janjua, Malik, McDonald, Timothy J., Sebastian, Shaji, Alexander, James L., Constable, Laura, Lee, James C., Murray, Charles D., Hart, Ailsa L., Irving, Peter M., Jones, Gareth-Rhys, Kok, Klaartje B., Lamb, Christopher A., Lees, Charlie W., Altmann, Daniel M., Boyton, Rosemary J., Goodhand, James R., Powell, Nick, Ahmad, Tariq

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Intermediate-term mortality and cardiac transplantation in infants with single-ventricle lesions: Risk factors and their interaction with shunt type von Tweddell, James S., MD, Sleeper, Lynn A., ScD, Ohye, Richard G., MD, Williams, Ismee A., MD, MS, Mahony, Lynn, MD, Pizarro, Christian, MD, Pemberton, Victoria L., RNC, MS, Frommelt, Peter C., MD, Bradley, Scott M., MD, Cnota, James F., MD, Hirsch, Jennifer, MD, MS, Kirshbom, Paul M., MD, Li, Jennifer S., MD, MHS, Pike, Nancy, RN, PhD, Puchalski, Michael, MD, Ravishankar, Chitra, MD, Jacobs, Jeffrey P., MD, Laussen, Peter C., MBBS, McCrindle, Brian W., MD, MPH

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Ageing hallmarks exhibit organ-specific temporal signatures von Schaum, Nicholas, Lehallier, Benoit, Hahn, Oliver, Pálovics, Róbert, Hosseinzadeh, Shayan, Lee, Song E., Sit, Rene, Lee, Davis P., Losada, Patricia Morán, Zardeneta, Macy E., Fehlmann, Tobias, Webber, James T., McGeever, Aaron, Calcuttawala, Kruti, Zhang, Hui, Berdnik, Daniela, Mathur, Vidhu, Tan, Weilun, Zee, Alexander, Tan, Michelle, Pisco, Angela Oliveira, Karkanias, Jim, Neff, Norma F., Keller, Andreas, Darmanis, Spyros, Quake, Stephen R., Wyss-Coray, Tony

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Heparanase inhibition preserves the endothelial glycocalyx in lung grafts and improves lung preservation and transplant outcomes von Noda, Kentaro, Philips, Brian J., Snyder, Mark E., Phillippi, Julie A., Sullivan, Mara, Stolz, Donna B., Ren, Xi, Luketich, James D., Sanchez, Pablo G.

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Consensus Recommendations for RBC Transfusion Practice in Critically Ill Children From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative von Valentine, Stacey L, Bembea, Melania M, Muszynski, Jennifer A, Cholette, Jill M, Doctor, Allan, Spinella, Phillip C, Steiner, Marie E, Tucci, Marisa, Hassan, Nabil E, Parker, Robert I, Lacroix, Jacques, Argent, Andrew, Carson, Jeffrey L, Remy, Kenneth E, Demaret, Pierre, Emeriaud, Guillaume, Kneyber, Martin C J, Guzzetta, Nina, Hall, Mark W, Macrae, Duncan, Karam, Oliver, Russell, Robert T, Stricker, Paul A, Vogel, Adam M, Tasker, Robert C, Turgeon, Alexis F, Schwartz, Steven M, Willems, Ariane, Josephson, Cassandra D, Luban, Naomi L C, Lehmann, Leslie E, Stanworth, Simon J, Zantek, Nicole D, Bunchman, Timothy E, Cheifetz, Ira M, Fortenberry, James D, Delaney, Meghan, van de Watering, Leo, Robinson, Karen A, Malone, Sara, Steffen, Katherine M, Bateman, Scot T

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Ten simple rules for effective computational research von Osborne, James M, Bernabeu, Miguel O, Bruna, Maria, Calderhead, Ben, Cooper, Jonathan, Dalchau, Neil, Dunn, Sara-Jane, Fletcher, Alexander G, Freeman, Robin, Groen, Derek, Knapp, Bernhard, McInerny, Greg J, Mirams, Gary R, Pitt-Francis, Joe, Sengupta, Biswa, Wright, David W, Yates, Christian A, Gavaghan, David J, Emmott, Stephen, Deane, Charlotte

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Patterns of Kidney Function Decline in Autosomal Dominant Polycystic Kidney Disease: A Post Hoc Analysis From the HALT-PKD Trials von Brosnahan, Godela M., Abebe, Kaleab Z., Moore, Charity G., Rahbari-Oskoui, Frederic F., Bae, Kyongtae T., Grantham, Jared J., Schrier, Robert W., Braun, William E., Chapman, Arlene B., Flessner, Michael F., Harris, Peter C., Hogan, Marie C., Perrone, Ronald D., Miskulin, Dana C., Steinman, Theodore I., Torres, Vicente E., Steinman, Theodore, Wei, Jesse, Czarnecki, Peter, Pedrosa, Ivan, Braun, William, Nurko, Saul, Remer, Erick, Chapman, Arlene, Martin, Diego, Rahbari-Oskoui, Frederic, Mittal, Pardeep, Torres, Vicente, Hogan, Marie C., El-Zoghby, Ziad, Harris, Peter, Glockner, James, King, Bernard, Perrone, Ronald, Halin, Neil, Miskulin, Dana, Schrier, Robert, Brosnahan, Godela, Gitomer, Berenice, Kelleher, Cass, Masoumi, Amirali, Patel, Nayana, Winklhofer, Franz, Grantham, Jared, Yu, Alan, Wang, Connie, Wetzel, Louis, Moore, Charity G., Bost, James E., Bae, Kyongtae, Abebe, Kaleab Z., Miller, J. Philip, Thompson, Paul A., Briggs, Josephine, Flessner, Michael, Meyers, Catherine M., Star, Robert, Shayman, James, Henrich, William, Greene, Tom, Leonard, Mary, McCullough, Peter, Moe, Sharon, Rocco, Michael, Wendler, David

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Whole-genome sequencing of a sporadic primary immunodeficiency cohort von Thaventhiran, James E. D., Lango Allen, Hana, Burren, Oliver S., Rae, William, Greene, Daniel, Staples, Emily, Zhang, Zinan, Farmery, James H. R., Simeoni, Ilenia, Rivers, Elizabeth, Maimaris, Jesmeen, Penkett, Christopher J., Stephens, Jonathan, Deevi, Sri V. V., Sanchis-Juan, Alba, Gleadall, Nicholas S., Thomas, Moira J., Sargur, Ravishankar B., Gordins, Pavels, Baxendale, Helen E., Brown, Matthew, Tuijnenburg, Paul, Worth, Austen, Hanson, Steven, Linger, Rachel J., Buckland, Matthew S., Rayner-Matthews, Paula J., Gilmour, Kimberly C., Samarghitean, Crina, Seneviratne, Suranjith L., Sansom, David M., Lynch, Andy G., Megy, Karyn, Ellinghaus, Eva, Ellinghaus, David, Jorgensen, Silje F., Karlsen, Tom H., Stirrups, Kathleen E., Cutler, Antony J., Kumararatne, Dinakantha S., Chandra, Anita, Edgar, J. David M., Herwadkar, Archana, Cooper, Nichola, Grigoriadou, Sofia, Huissoon, Aarnoud P., Goddard, Sarah, Jolles, Stephen, Schuetz, Catharina, Boschann, Felix, Lyons, Paul A., Hurles, Matthew E., Savic, Sinisa, Burns, Siobhan O., Kuijpers, Taco W., Turro, Ernest, Ouwehand, Willem H., Thrasher, Adrian J., Smith, Kenneth G. C.

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