Inositol Pyrophosphates Mediate the DNA-PK/ATM-p53 Cell Death Pathway by Regulating CK2 Phosphorylation of Tti1/Tel2 von Rao, Feng, Cha, Jiyoung, Xu, Jing, Xu, Risheng, Vandiver, M. Scott, Tyagi, Richa, Tokhunts, Robert, Koldobskiy, Michael A., Fu, Chenglai, Barrow, Roxanne, Wu, Mingxuan, Fiedler, Dorothea, Barrow, James C., Snyder, Solomon H.

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The Role of Inositol Hexakisphosphate Kinase in the Central Nervous System von Heitmann, Tyler, Barrow, James C

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Inositol pyrophosphates promote tumor growth and metastasis by antagonizing liver kinase B1 von Rao, Feng, Xu, Jing, Fu, Chenglai, Cha, Jiyoung Y., Gadalla, Moataz M., Xu, Risheng, Barrow, James C., Snyder, Solomon H.

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Inositol hexakisphosphate (IP6) generated by IP5K mediates cullin-COP9 signalosome interactions and CRL function von Scherer, Paul C., Ding, Yan, Liu, Zhiqing, Xu, Jing, Mao, Haibin, Barrow, James C., Wei, Ning, Zheng, Ning, Snyder, Solomon H., Rao, Feng

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DNA intercalator BMH-21 inhibits RNA polymerase I independent of DNA damage response von Colis, Laureen, Peltonen, Karita, Sirajuddin, Paul, Liu, Hester, Sanders, Sara, Ernst, Glen, Barrow, James C, Laiho, Marikki

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The IP6K Inhibitor LI-2242 Ameliorates Diet-Induced Obesity, Hyperglycemia, and Hepatic Steatosis in Mice by Improving Cell Metabolism and Insulin Signaling von Mukherjee, Sandip, Chakraborty, Molee, Haubner, Jake, Ernst, Glen, DePasquale, Michael, Carpenter, Danielle, Barrow, James C, Chakraborty, Anutosh

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Inhibition of Catechol- O -methyltransferase Does Not Alter Effort-Related Choice Behavior in a Fixed Ratio/Concurrent Chow Task in Male Mice von DeBrosse, Adrienne C, Wheeler, Abigail M, Barrow, James C, Carr, Gregory V

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TNP [N2-(m-Trifluorobenzyl), N6-(p-nitrobenzyl)purine] ameliorates diet induced obesity and insulin resistance via inhibition of the IP6K1 pathway von Ghoshal, Sarbani, Zhu, Qingzhang, Asteian, Alice, Lin, Hua, Xu, Haifei, Ernst, Glen, Barrow, James C, Xu, Baoji, Cameron, Michael D, Kamenecka, Theodore M, Chakraborty, Anutosh

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The Importance of PK–PD von Barrow, James C., Lindsley, Craig W.

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Classics in Chemical Neuroscience: Diazepam (Valium) von Calcaterra, Nicholas E, Barrow, James C

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A Method for Touchscreen‐Based Oral Self‐Administration of Oxycodone in Mice von Afzal, Anum, Barrow, James C., Carr, Gregory V.

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Synthesis and Evaluation of Heterocyclic Catechol Mimics as Inhibitors of Catechol-O-methyltransferase (COMT) von Harrison, Scott T, Poslusney, Michael S, Mulhearn, James J, Zhao, Zhijian, Kett, Nathan R, Schubert, Jeffrey W, Melamed, Jeffrey Y, Allison, Timothy J, Patel, Sangita B, Sanders, John M, Sharma, Sujata, Smith, Robert F, Hall, Dawn L, Robinson, Ronald G, Sachs, Nancy A, Hutson, Pete H, Wolkenberg, Scott E, Barrow, James C

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Adipocyte-specific deletion of Ip6k1 reduces diet-induced obesity by enhancing AMPK-mediated thermogenesis von Zhu, Qingzhang, Ghoshal, Sarbani, Rodrigues, Ana, Gao, Su, Asterian, Alice, Kamenecka, Theodore M, Barrow, James C, Chakraborty, Anutosh

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Synthesis and characterization of novel isoform-selective IP6K1 inhibitors von Wormald, Michael M., Ernst, Glen, Wei, Huijun, Barrow, James C.

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A Medicinal Chemist’s Perspective on Transitioning from Industry to Academic Drug Discovery von Barrow, James C

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Post-weaning social isolation increases ΔFosB/FosB protein expression in sex-specific patterns in the prelimbic/infralimbic cortex and hippocampus in mice von Noback, Michael, Zhang, Gongliang, White, Noelle, Barrow, James C., Carr, Gregory V.

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Identification and Characterization of a Blood–Brain Barrier Penetrant Inositol Hexakisphosphate Kinase (IP6K) Inhibitor von Heitmann, Tyler, Liao, Gangling, Ernst, Glen, Poslusney, Michael, van Kralingen, Thomas, Li, Ye, Masi, Megan, DePasquale, Michael, Buchler, Ingrid, Wei, Huijun, Carr, Gregory V., Shlevkov, Evgeny, Lu, Mengsi, Jessen, Henning, Barrow, James C.

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Total Syntheses of Vancomycin and Eremomycin Aglycons von Evans, David A., Wood, Michael R., Trotter, B. Wesley, Richardson, Timothy I., Barrow, James C., Katz, Jeffrey L.

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Asymmetric Synthesis of the Squalene Synthase Inhibitor Zaragozic Acid C von Evans, David A, Barrow, James C, Leighton, James L, Robichaud, Albert J, Sefkow, Michael

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Degrading stimuli by reducing image resolution impairs performance in a rodent continuous performance test von DeBrosse, Adrienne C., Li, Ye, Wiseman, Robyn, Ross, Racine, Garrison, Sy’Keria, Hallock, Henry L., Barrow, James C., Martinowich, Keri, Carr, Gregory V.

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