Global Phosphoproteomic Analysis of Human Skeletal Muscle Reveals a Network of Exercise-Regulated Kinases and AMPK Substrates von Hoffman, Nolan J., Parker, Benjamin L., Chaudhuri, Rima, Fisher-Wellman, Kelsey H., Kleinert, Maximilian, Humphrey, Sean J., Yang, Pengyi, Holliday, Mira, Trefely, Sophie, Fazakerley, Daniel J., Stöckli, Jacqueline, Burchfield, James G., Jensen, Thomas E., Jothi, Raja, Kiens, Bente, Wojtaszewski, Jørgen F.P., Richter, Erik A., James, David E.

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Protein Phosphorylation: A Major Switch Mechanism for Metabolic Regulation von Humphrey, Sean J, James, David E, Mann, Matthias

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A Positive Feedback Loop between Akt and mTORC2 via SIN1 Phosphorylation von Yang, Guang, Murashige, Danielle S., Humphrey, Sean J., James, David E.

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Muscle and adipose tissue insulin resistance: malady without mechanism? von Fazakerley, Daniel J., Krycer, James R., Kearney, Alison L., Hocking, Samantha L., James, David E.

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Drug Screening in Human PSC-Cardiac Organoids Identifies Pro-proliferative Compounds Acting via the Mevalonate Pathway von Mills, Richard J., Parker, Benjamin L., Quaife-Ryan, Gregory A., Voges, Holly K., Needham, Elise J., Bornot, Aurelie, Ding, Mei, Andersson, Henrik, Polla, Magnus, Elliott, David A., Drowley, Lauren, Clausen, Maryam, Plowright, Alleyn T., Barrett, Ian P., Wang, Qing-Dong, James, David E., Porrello, Enzo R., Hudson, James E.

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Illuminating the dark phosphoproteome von Needham, Elise J, Parker, Benjamin L, Burykin, Timur, James, David E, Humphrey, Sean J

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GLUT4 exocytosis von Stöckli, Jacqueline, Fazakerley, Daniel J, James, David E

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The serine/threonine kinase ULK1 is a target of multiple phosphorylation events von Bach, Markus, Larance, Mark, James, David E, Ramm, Georg

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Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2 von Humphrey, Sean J., Yang, Guang, Yang, Pengyi, Fazakerley, Daniel J., Stöckli, Jacqueline, Yang, Jean Y., James, David E.

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Phosphoproteomics reveals rewiring of the insulin signaling network and multi-nodal defects in insulin resistance von Fazakerley, Daniel J., van Gerwen, Julian, Cooke, Kristen C., Duan, Xiaowen, Needham, Elise J., Díaz-Vegas, Alexis, Madsen, Søren, Norris, Dougall M., Shun-Shion, Amber S., Krycer, James R., Burchfield, James G., Yang, Pengyi, Wade, Mark R., Brozinick, Joseph T., James, David E., Humphrey, Sean J.

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Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance von Fazakerley, Daniel J, Chaudhuri, Rima, Yang, Pengyi, Maghzal, Ghassan J, Thomas, Kristen C, Krycer, James R, Humphrey, Sean J, Parker, Benjamin L, Fisher-Wellman, Kelsey H, Meoli, Christopher C, Hoffman, Nolan J, Diskin, Ciana, Burchfield, James G, Cowley, Mark J, Kaplan, Warren, Modrusan, Zora, Kolumam, Ganesh, Yang, Jean Yh, Chen, Daniel L, Samocha-Bonet, Dorit, Greenfield, Jerry R, Hoehn, Kyle L, Stocker, Roland, James, David E

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Lactate production is a prioritized feature of adipocyte metabolism von Krycer, James R., Quek, Lake-Ee, Francis, Deanne, Fazakerley, Daniel J., Elkington, Sarah D., Diaz-Vegas, Alexis, Cooke, Kristen C., Weiss, Fiona C., Duan, Xiaowen, Kurdyukov, Sergey, Zhou, Ping-Xin, Tambar, Uttam K., Hirayama, Akiyoshi, Ikeda, Satsuki, Kamei, Yushi, Soga, Tomoyoshi, Cooney, Gregory J., James, David E.

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Dynamic modelling of the PI3K/MTOR signalling network uncovers biphasic dependence of mTORC1 activity on the mTORC2 subunit SIN1 von Ghomlaghi, Milad, Yang, Guang, Shin, Sung-Young, James, David E, Nguyen, Lan K

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PhosR enables processing and functional analysis of phosphoproteomic data von Kim, Hani Jieun, Kim, Taiyun, Hoffman, Nolan J., Xiao, Di, James, David E., Humphrey, Sean J., Yang, Pengyi

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Defining the protein and lipid constituents of tubular recycling endosomes von Farmer, Trey, Xie, Shuwei, Naslavsky, Naava, Stöckli, Jacqueline, James, David E., Caplan, Steve

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mTORC1 Is a Major Regulatory Node in the FGF21 Signaling Network in Adipocytes von Minard, Annabel Y., Tan, Shi-Xiong, Yang, Pengyi, Fazakerley, Daniel J., Domanova, Westa, Parker, Benjamin L., Humphrey, Sean J., Jothi, Raja, Stöckli, Jacqueline, James, David E.

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The aetiology and molecular landscape of insulin resistance von James, David E., Stöckli, Jacqueline, Birnbaum, Morris J.

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Core functional nodes and sex-specific pathways in human ischaemic and dilated cardiomyopathy von Li, Mengbo, Parker, Benjamin L., Pearson, Evangeline, Hunter, Benjamin, Cao, Jacob, Koay, Yen Chin, Guneratne, Oneka, James, David E., Yang, Jean, Lal, Sean, O’Sullivan, John F.

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Proteome-wide systems genetics identifies UFMylation as a regulator of skeletal muscle function von Molendijk, Jeffrey, Blazev, Ronnie, Mills, Richard J, Ng, Yaan-Kit, Watt, Kevin I, Chau, Daryn, Gregorevic, Paul, Crouch, Peter J, Hilton, James B W, Lisowski, Leszek, Zhang, Peixiang, Reue, Karen, Lusis, Aldons J, Hudson, James E, James, David E, Seldin, Marcus M, Parker, Benjamin L

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Proteomic Analysis of GLUT4 Storage Vesicles Reveals Tumor Suppressor Candidate 5 (TUSC5) as a Novel Regulator of Insulin Action in Adipocytes von Fazakerley, Daniel J., Naghiloo, Sheyda, Chaudhuri, Rima, Koumanov, Françoise, Burchfield, James G., Thomas, Kristen C., Krycer, James R., Prior, Matthew J., Parker, Ben L., Murrow, Beverley A., Stöckli, Jacqueline, Meoli, Christopher C., Holman, Geoffrey D., James, David E.

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