A pathway coordinated by DELE1 relays mitochondrial stress to the cytosol von Fessler, Evelyn, Eckl, Eva-Maria, Schmitt, Sabine, Mancilla, Igor Alves, Meyer-Bender, Matthias F., Hanf, Monika, Philippou-Massier, Julia, Krebs, Stefan, Zischka, Hans, Jae, Lucas T.

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DELE1 tracks perturbed protein import and processing in human mitochondria von Fessler, Evelyn, Krumwiede, Luisa, Jae, Lucas T.

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Gene essentiality and synthetic lethality in haploid human cells von Blomen, Vincent A., Májek, Peter, Jae, Lucas T., Bigenzahn, Johannes W., Nieuwenhuis, Joppe, Staring, Jacqueline, Sacco, Roberto, van Diemen, Ferdy R., Olk, Nadine, Stukalov, Alexey, Marceau, Caleb, Janssen, Hans, Carette, Jan E., Bennett, Keiryn L., Colinge, Jacques, Superti-Furga, Giulio, Brummelkamp, Thijn R.

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Identification of CMTM6 and CMTM4 as PD-L1 protein regulators von Mezzadra, Riccardo, Sun, Chong, Jae, Lucas T., Gomez-Eerland, Raquel, de Vries, Evert, Wu, Wei, Logtenberg, Meike E. W., Slagter, Maarten, Rozeman, Elisa A., Hofland, Ingrid, Broeks, Annegien, Horlings, Hugo M., Wessels, Lodewyk F. A., Blank, Christian U., Xiao, Yanling, Heck, Albert J. R., Borst, Jannie, Brummelkamp, Thijn R., Schumacher, Ton N. M.

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SLFN11 can sensitize tumor cells towards IFN-γ-mediated T cell killing von Mezzadra, Riccardo, de Bruijn, Marjolein, Jae, Lucas T, Gomez-Eerland, Raquel, Duursma, Anja, Scheeren, Ferenc A, Brummelkamp, Thijn R, Schumacher, Ton N

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Protocadherin-1 is essential for cell entry by New World hantaviruses von Jangra, Rohit K., Herbert, Andrew S., Li, Rong, Jae, Lucas T., Kleinfelter, Lara M., Slough, Megan M., Barker, Sarah L., Guardado-Calvo, Pablo, Román-Sosa, Gleyder, Dieterle, M. Eugenia, Kuehne, Ana I., Muena, Nicolás A., Wirchnianski, Ariel S., Nyakatura, Elisabeth K., Fels, J. Maximilian, Ng, Melinda, Mittler, Eva, Pan, James, Bharrhan, Sushma, Wec, Anna Z., Lai, Jonathan R., Sidhu, Sachdev S., Tischler, Nicole D., Rey, Félix A., Moffat, Jason, Brummelkamp, Thijn R., Wang, Zhongde, Dye, John M., Chandran, Kartik

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Sensing, signaling and surviving mitochondrial stress von Eckl, Eva-Maria, Ziegemann, Olga, Krumwiede, Luisa, Fessler, Evelyn, Jae, Lucas T.

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BRCA2 deficiency instigates cGAS-mediated inflammatory signaling and confers sensitivity to tumor necrosis factor-alpha-mediated cytotoxicity von Heijink, Anne Margriet, Talens, Francien, Jae, Lucas T., van Gijn, Stephanie E., Fehrmann, Rudolf S. N., Brummelkamp, Thijn R., van Vugt, Marcel A. T. M.

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Lassa virus entry requires a trigger-induced receptor switch von Jae, Lucas T., Raaben, Matthijs, Herbert, Andrew S., Kuehne, Ana I., Wirchnianski, Ariel S., Soh, Timothy K., Stubbs, Sarah H., Janssen, Hans, Damme, Markus, Saftig, Paul, Whelan, Sean P., Dye, John M., Brummelkamp, Thijn R.

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Deciphering the Glycosylome of Dystroglycanopathies Using Haploid Screens for Lassa Virus Entry von Jae, Lucas T., Raaben, Matthijs, Riemersma, Moniek, van Beusekom, Ellen, Blomen, Vincent A., Velds, Arno, Kerkhoven, Ron. M., Carette, Jan E., Topaloglu, Haluk, Meinecke, Peter, Wessels, Marja W., Lefeber, Dirk J., Whelan, Sean P., van Bokhoven, Hans, Brummelkamp, Thijn R.

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Emerging intracellular receptors for hemorrhagic fever viruses von Jae, Lucas T, Brummelkamp, Thijn R

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NRP2 and CD63 Are Host Factors for Lujo Virus Cell Entry von Raaben, Matthijs, Jae, Lucas T., Herbert, Andrew S., Kuehne, Ana I., Stubbs, Sarah H., Chou, Yi-ying, Blomen, Vincent A., Kirchhausen, Tomas, Dye, John M., Brummelkamp, Thijn R., Whelan, Sean P.

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A Haploid Genetic Screen Identifies Heparan Sulfate Proteoglycans Supporting Rift Valley Fever Virus Infection von Riblett, Amber M, Blomen, Vincent A, Jae, Lucas T, Altamura, Louis A, Doms, Robert W, Brummelkamp, Thijn R, Wojcechowskyj, Jason A

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A mitochondrial iron-responsive pathway regulated by DELE1 von Sekine, Yusuke, Houston, Ryan, Eckl, Eva-Maria, Fessler, Evelyn, Narendra, Derek P., Jae, Lucas T., Sekine, Shiori

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Genetic wiring maps of single-cell protein states reveal an off-switch for GPCR signalling von Brockmann, Markus, Blomen, Vincent A., Nieuwenhuis, Joppe, Stickel, Elmer, Raaben, Matthijs, Bleijerveld, Onno B., Altelaar, A. F. Maarten, Jae, Lucas T., Brummelkamp, Thijn R.

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OMA1 mediates local and global stress responses against protein misfolding in CHCHD10 mitochondrial myopathy von Shammas, Mario K, Huang, Xiaoping, Wu, Beverly P, Fessler, Evelyn, Song, Insung, Randolph, Nicholas P, Li, Yan, Bleck, Christopher Ke, Springer, Danielle A, Fratter, Carl, Barbosa, Ines A, Powers, Andrew F, Quirós, Pedro M, Lopez-Otin, Carlos, Jae, Lucas T, Poulton, Joanna, Narendra, Derek P

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DNA Structure-Specific Cleavage of DNA-Protein Crosslinks by the SPRTN Protease von Reinking, Hannah K., Kang, Hyun-Seo, Götz, Maximilian J., Li, Hao-Yi, Kieser, Anja, Zhao, Shubo, Acampora, Aleida C., Weickert, Pedro, Fessler, Evelyn, Jae, Lucas T., Sattler, Michael, Stingele, Julian

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Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation von Stafford, Che A., Gassauer, Alicia-Marie, de Oliveira Mann, Carina C., Tanzer, Maria C., Fessler, Evelyn, Wefers, Benedikt, Nagl, Dennis, Kuut, Gunnar, Sulek, Karolina, Vasilopoulou, Catherine, Schwojer, Sophia J., Wiest, Andreas, Pfautsch, Marie K., Wurst, Wolfgang, Yabal, Monica, Fröhlich, Thomas, Mann, Matthias, Gisch, Nicolas, Jae, Lucas T., Hornung, Veit

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The histone chaperone ANP32B regulates chromatin incorporation of the atypical human histone variant macroH2A von Mandemaker, Imke K., Fessler, Evelyn, Corujo, David, Kotthoff, Christiane, Wegerer, Andreas, Rouillon, Clément, Buschbeck, Marcus, Jae, Lucas T., Mattiroli, Francesca, Ladurner, Andreas G.

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Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism von Loregger, Anke, Raaben, Matthijs, Nieuwenhuis, Joppe, Tan, Josephine M. E., Jae, Lucas T., van den Hengel, Lisa G., Hendrix, Sebastian, van den Berg, Marlene, Scheij, Saskia, Song, Ji-Ying, Huijbers, Ivo J., Kroese, Lona J., Ottenhoff, Roelof, van Weeghel, Michel, van de Sluis, Bart, Brummelkamp, Thijn, Zelcer, Noam

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