Epigenetic Regulation of Intestinal Stem Cells and Disease: A Balancing Act of DNA and Histone Methylation von Lorzadeh, Alireza, Romero-Wolf, Maile, Goel, Ajay, Jadhav, Unmesh

Volltext

Replicational Dilution of H3K27me3 in Mammalian Cells and the Role of Poised Promoters von Jadhav, Unmesh, Manieri, Elisa, Nalapareddy, Kodandaramireddy, Madha, Shariq, Chakrabarti, Shaon, Wucherpfennig, Kai, Barefoot, Megan, Shivdasani, Ramesh A.

Volltext

Acquired Tissue-Specific Promoter Bivalency Is a Basis for PRC2 Necessity in Adult Cells von Jadhav, Unmesh, Nalapareddy, Kodandaramireddy, Saxena, Madhurima, O’Neill, Nicholas K., Pinello, Luca, Yuan, Guo-Cheng, Orkin, Stuart H., Shivdasani, Ramesh A.

Volltext

Extensive Recovery of Embryonic Enhancer and Gene Memory Stored in Hypomethylated Enhancer DNA von Jadhav, Unmesh, Cavazza, Alessia, Banerjee, Kushal K., Xie, Huafeng, O’Neill, Nicholas K., Saenz-Vash, Veronica, Herbert, Zachary, Madha, Shariq, Orkin, Stuart H., Zhai, Huili, Shivdasani, Ramesh A.

Volltext

Creb5 establishes the competence for Prg4 expression in articular cartilage von Zhang, Cheng-Hai, Gao, Yao, Jadhav, Unmesh, Hung, Han-Hwa, Holton, Kristina M., Grodzinsky, Alan J., Shivdasani, Ramesh A., Lassar, Andrew B.

Volltext

Single-Cell Transcript Profiles Reveal Multilineage Priming in Early Progenitors Derived from Lgr5+ Intestinal Stem Cells von Kim, Tae-Hee, Saadatpour, Assieh, Guo, Guoji, Saxena, Madhurima, Cavazza, Alessia, Desai, Niyati, Jadhav, Unmesh, Jiang, Lan, Rivera, Miguel N., Orkin, Stuart H., Yuan, Guo-Cheng, Shivdasani, Ramesh A.

Volltext

Response of neuroblastoma cells to ionizing radiation : Modulation of in vitro invasiveness and angiogenesis of human microvascular endothelial cells von JADHAV, Unmesh, MOHANAM, Sanjeeva

Volltext

Ascl2-Dependent Cell Dedifferentiation Drives Regeneration of Ablated Intestinal Stem Cells von Murata, Kazutaka, Jadhav, Unmesh, Madha, Shariq, van Es, Johan, Dean, Justin, Cavazza, Alessia, Wucherpfennig, Kai, Michor, Franziska, Clevers, Hans, Shivdasani, Ramesh A.

Volltext

Natural Selection, Crypt Fitness, and Pol III Dependency in the Intestine von Jadhav, Unmesh, PhD, Shivdasani, Ramesh A., MD, PhD

Volltext

Dynamic Reorganization of Chromatin Accessibility Signatures during Dedifferentiation of Secretory Precursors into Lgr5+ Intestinal Stem Cells von Jadhav, Unmesh, Saxena, Madhurima, O’Neill, Nicholas K., Saadatpour, Assieh, Yuan, Guo-Cheng, Herbert, Zachary, Murata, Kazutaka, Shivdasani, Ramesh A.

Volltext

Dietary Isothiocyanate Iberin Inhibits Growth and Induces Apoptosis in Human Glioblastoma Cells von Jadhav, Unmesh, Ezhilarasan, Ravesanker, Smith, Steven F., Smith, Mark A., Mohanam, Sanjeeva

Volltext

Dissecting Cell Lineages: From Microscope to Kaleidoscope von Jadhav, Unmesh, Shivdasani, Ramesh A.

Volltext

Crypt density and recruited enhancers underlie intestinal tumour initiation von Gaynor, Liam, Singh, Harshabad, Tie, Guodong, Badarinath, Krithika, Madha, Shariq, Mancini, Andrew, Bhattacharya, Swarnabh, Hoshino, Mikio, de Sauvage, Frederic J, Murata, Kazutaka, Jadhav, Unmesh, Shivdasani, Ramesh A

Volltext

Ornithine aminotransferase supports polyamine synthesis in pancreatic cancer von Lee, Min-Sik, Dennis, Courtney, Naqvi, Insia, Dailey, Lucas, Lorzadeh, Alireza, Ye, George, Zaytouni, Tamara, Adler, Ashley, Hitchcock, Daniel S., Lin, Lin, Hoffman, Megan T., Bhuiyan, Aladdin M., Barth, Jaimie L., Machacek, Miranda E., Mino-Kenudson, Mari, Dougan, Stephanie K., Jadhav, Unmesh, Clish, Clary B., Kalaany, Nada Y.

Volltext

Abstract 2456: Distinct metabolic dependencies in pancreatic cancer von Kalaany, Nada, Lee, Min-Sik, Dennis, Courtney, Lorzadeh, Alireza, Hoffman, Megan, Mino-Kenudson, Mari, Dougan, Stephanie, Jadhav, Unmesh, Clish, Clary

Volltext

Hypogonadotropic hypogonadism in subjects with DAX1 mutations von Jadhav, Unmesh, Harris, Rebecca M., Jameson, J. Larry

Volltext

Abstract PO-028: Pancreatic ductal adenocarcinoma is dependent on an unconventional pathway for polyamine synthesis von Lee, Min-Sik, Naqvi, Insia, Dennis, Courtney, Dailey, Lucas, Lorzadeh, Alireza, Zaytouni, Tamara, Adler, Ashley, Hitchcock, Daniel S., Lin, Lin, Jadhav, Unmesh, Clish, Clary B., Kalaany, Nada Y.

Volltext

Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1 von Tsai, Pei-Yun, Lee, Min-Sik, Jadhav, Unmesh, Naqvi, Insia, Madha, Shariq, Adler, Ashley, Mistry, Meeta, Naumenko, Sergey, Lewis, Caroline A., Hitchcock, Daniel S., Roberts, Frederick R., DelNero, Peter, Hank, Thomas, Honselmann, Kim C., Oyarvide, Vicente Morales, Mino-Kenudson, Mari, Clish, Clary B., Shivdasani, Ramesh A., Kalaany, Nada Y.

Volltext

Transcription factor-dependent 'anti-repressive' mammalian enhancers exclude H3K27me3 from extended genomic domains von Saxena, Madhurima, Roman, Adrianna K San, O'Neill, Nicholas K, Sulahian, Rita, Jadhav, Unmesh, Shivdasani, Ramesh A

Volltext

Steroidogenic Factor-1 (SF-1)-Driven Differentiation of Murine Embryonic Stem (ES) Cells into a Gonadal Lineage von Jadhav, Unmesh, Jameson, J. Larry

Volltext