Age and sex dimorphisms contribute to the severity of bleomycin-induced lung injury and fibrosis von Redente, Elizabeth F, Jacobsen, Kristen M, Solomon, Joshua J, Lara, Abigail R, Faubel, Sarah, Keith, Rebecca C, Henson, Peter M, Downey, Gregory P, Riches, David W H

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Bortezomib sensitizes human renal cell carcinomas to TRAIL apoptosis through increased activation of caspase-8 in the death-inducing signaling complex von Brooks, Alan D, Jacobsen, Kristen M, Li, Wenqing, Shanker, Anil, Sayers, Thomas J

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Influenza Virus-like Particle-Based Hybrid Vaccine Containing RBD Induces Immunity against Influenza and SARS-CoV-2 Viruses von Bommireddy, Ramireddy, Stone, Shannon, Bhatnagar, Noopur, Kumari, Pratima, Munoz, Luis E, Oh, Judy, Kim, Ki-Hye, Berry, Jameson T L, Jacobsen, Kristen M, Jaafar, Lahcen, Naing, Swe-Htet, Blackerby, Allison N, Gaag, Tori Van der, Wright, Chloe N, Lai, Lilin, Pack, Christopher D, Ramachandiran, Sampath, Suthar, Mehul S, Kang, Sang-Moo, Kumar, Mukesh, Reddy, Shaker J C, Selvaraj, Periasamy

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MerTK inhibition in tumor leukocytes decreases tumor growth and metastasis von Cook, Rebecca S, Jacobsen, Kristen M, Wofford, Anne M, DeRyckere, Deborah, Stanford, Jamie, Prieto, Anne L, Redente, Elizabeth, Sandahl, Melissa, Hunter, Debra M, Strunk, Karen E, Graham, Douglas K, Earp, 3rd, H Shelton

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MERTK inhibition alters the PD-1 axis and promotes anti-leukemia immunity (vol 3, e97941, 2018) von Lee-Sherick, Alisa B., Jacobsen, Kristen M., Henry, Curtis J., Huey, Madeline G., Parker, Rebecca E., Page, Lauren S., Hill, Amanda A., Wang, Xiaodong, Frye, Stephen V., Earp, Shelton, Jordan, Craig T., DeRyckere, Deborah, Graham, Douglas K.

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Mer receptor tyrosine kinase is a novel therapeutic target in pediatric B-cell acute lymphoblastic leukemia von Linger, Rachel M.A., DeRyckere, Deborah, Brandão, Luis, Sawczyn, Kelly K., Jacobsen, Kristen M., Liang, Xiayuan, Keating, Amy K., Graham, Douglas K.

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MERTK inhibition selectively activates a DC – T-cell axis to provide anti-leukemia immunity von Huelse, Justus M., Bhasin, Swati S., Jacobsen, Kristen M., Yim, Juhye, Thomas, Beena E., Branella, Gianna M., Bakhtiari, Mojtaba, Chimenti, Madison L., Baxter, Travon A., Raikar, Sunil S., Wang, Xiaodong, Frye, Stephen V., Henry, Curtis J., Earp, H. Shelton, Bhasin, Manoj, DeRyckere, Deborah, Graham, Douglas K.

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UNC2025, a MERTK Small-Molecule Inhibitor, Is Therapeutically Effective Alone and in Combination with Methotrexate in Leukemia Models von DeRyckere, Deborah, Lee-Sherick, Alisa B, Huey, Madeline G, Hill, Amanda A, Tyner, Jeffrey W, Jacobsen, Kristen M, Page, Lauren S, Kirkpatrick, Gregory G, Eryildiz, Fatma, Montgomery, Stephanie A, Zhang, Weihe, Wang, Xiaodong, Frye, Stephen V, Earp, H Shelton, Graham, Douglas K

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Mer receptor tyrosine kinase is a therapeutic target in pre–B-cell acute lymphoblastic leukemia von Linger, Rachel M.A., Lee-Sherick, Alisa B., DeRyckere, Deborah, Cohen, Rebecca A., Jacobsen, Kristen M., McGranahan, Amy, Brandão, Luis N., Winges, Amanda, Sawczyn, Kelly K., Liang, Xiayuan, Keating, Amy K., Tan, Aik Choon, Earp, H. Shelton, Graham, Douglas K.

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MERTK inhibition alters the PD-1 axis and promotes anti-leukemia immunity von Lee-Sherick, Alisa B, Jacobsen, Kristen M, Henry, Curtis J, Huey, Madeline G, Parker, Rebecca E, Page, Lauren S, Hill, Amanda A, Wang, Xiaodong, Frye, Stephen V, Earp, H Shelton, Jordan, Craig T, DeRyckere, Deborah, Graham, Douglas K

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Antigen Presented by Tumors In vivo Determines the Nature of CD8+ T-Cell Cytotoxicity von SHANKER, Anil, BROOKS, Alan D, JACOBSEN, Kristen M, WINE, John W, WILTROUT, Robert H, YAGITA, Hideo, SAYERS, Thomas J

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Abstract A35: MERTK inhibition induces an anti-leukemia dendritic cell – T cell axis while TYRO3 inhibition protects by a separate mechanism von Huelse, Justus M, Bhasin, Swati S, Jacobsen, Kristen M, Thomas, Beena E, Chimenti, Madison L, Baxter, Travon A, Wang, Xiaodong, Frye, Stephen V, Henry, Curtis J, Earp, H. Shelton, Bhasin, Manoj, DeRyckere, Deborah, Graham, Douglas K

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MERTK inhibition in the leukemia microenvironment promotes a therapeutic immune response to acute lymphoblastic leukemia von Jacobsen, Kristen M, Lee-Sherick, Alisa B., Huey, Madeline G., Page, Lauren S., Zhang, Weihe, Wang, Xiaodong, Fyre, Stephen V., Earp, H. Shelton, Jordan, Craig T., DeRyckere, Deborah, Graham, Douglas K.

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Abstract 3637: Targeted inhibition of MER tyrosine kinase in the tumor microenvironment decreases tumor growth in a mouse model of breast cancer von Jacobsen, Kristen M., DeRyckere, Deborah, Zhang, Weihe, Wang, Xiaodong, Frye, Stephen V., Earp, H. Shelton, Graham, Douglas K.

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Abstract A110: Inhibition of MerTK in tumor infiltrating leukocytes decreases tumor growth in a mouse model of breast cancer von Jacobsen, Kristen M., Cook, Rebecca S., DeRyckere, Deborah, Stanford, Jamie, Hunter, Debra M., Wang, Xiaodong, Frye, Stephen, Graham, Douglas K., Earp, H. Shelton

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Bortezomib sensitizes human renal cell carcinomas to TRAIL apoptosis via increased activation of caspase-8 in the death-inducing signaling complex von Brooks, Alan D., Jacobsen, Kristen M., Li, Wenqing, Shanker, Anil, Sayers, Thomas J.

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Age and sex dimorphisms contribute to the severity of bleomycin-induced lung injury and fibrosis von REDENTE, Elizabeth F, JACOBSEN, Kristen M, SOLOMON, Joshua J, LARA, Abigail R, FAUBEL, Sarah, KEITH, Rebecca C, HENSON, Peter M, DOWNEY, Gregory P, RICHES, David W. H

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Correlating transcription and protein expression profiles of immune biomarkers following lipopolysaccharide exposure in lung epithelial cells von Jacobsen, Daniel E, Montoya, Makaela M, Llewellyn, Trent R, Martinez, Kaitlyn, Wilding, Kristen M, Lenz, Kiersten D, Manore, Carrie A, Kubicek-Sutherland, Jessica Z, Mukundan, Harshini

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Efficacy of the mRNA-1273 SARS-CoV-2 Vaccine at Completion of Blinded Phase von El Sahly, Hana M, Baden, Lindsey R, Essink, Brandon, Doblecki-Lewis, Susanne, Martin, Judith M, Anderson, Evan J, Campbell, Thomas B, Clark, Jesse, Jackson, Lisa A, Fichtenbaum, Carl J, Zervos, Marcus, Rankin, Bruce, Eder, Frank, Feldman, Gregory, Kennelly, Christina, Han-Conrad, Laurie, Levin, Michael, Neuzil, Kathleen M, Corey, Lawrence, Gilbert, Peter, Janes, Holly, Follmann, Dean, Marovich, Mary, Polakowski, Laura, Mascola, John R, Ledgerwood, Julie E, Graham, Barney S, August, Allison, Clouting, Heather, Deng, Weiping, Han, Shu, Leav, Brett, Manzo, Deb, Pajon, Rolando, Schödel, Florian, Tomassini, Joanne E, Zhou, Honghong, Miller, Jacqueline

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Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine von Baden, Lindsey R, El Sahly, Hana M, Essink, Brandon, Kotloff, Karen, Frey, Sharon, Novak, Rick, Diemert, David, Spector, Stephen A, Rouphael, Nadine, Creech, C. Buddy, McGettigan, John, Khetan, Shishir, Segall, Nathan, Solis, Joel, Brosz, Adam, Fierro, Carlos, Schwartz, Howard, Neuzil, Kathleen, Corey, Larry, Gilbert, Peter, Janes, Holly, Follmann, Dean, Marovich, Mary, Mascola, John, Polakowski, Laura, Ledgerwood, Julie, Graham, Barney S, Bennett, Hamilton, Pajon, Rolando, Knightly, Conor, Leav, Brett, Deng, Weiping, Zhou, Honghong, Han, Shu, Ivarsson, Melanie, Miller, Jacqueline, Zaks, Tal

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