Glycosylation inhibitors in biology and medicine von Jacob, Gary S

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Deactivation of Akt and STAT3 signaling promotes apoptosis, inhibits proliferation, and enhances the sensitivity of hepatocellular carcinoma cells to an anticancer agent, Atiprimod von Choudhari, Sweeta R, Khan, Muhammad A, Harris, Genesis, Picker, Donald, Jacob, Gary S, Block, Timothy, Shailubhai, Kunwar

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A clinically relevant SCID-hu in vivo model of human multiple myeloma von Tassone, Pierfrancesco, Neri, Paola, Carrasco, Daniel R., Burger, Renate, Goldmacher, Victor S., Fram, Robert, Munshi, Vidit, Shammas, Masood A., Catley, Laurence, Jacob, Gary S., Venuta, Salvatore, Anderson, Kenneth C., Munshi, Nikhil C.

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Plecanatide, an Oral Guanylate Cyclase C Agonist Acting Locally in the Gastrointestinal Tract, Is Safe and Well-Tolerated in Single Doses von Shailubhai, Kunwar, Comiskey, Stephen, Foss, John A., Feng, Rong, Barrow, Laura, Comer, Gail M., Jacob, Gary S.

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Mo1316 Structural and Dynamic Features of Plecanatide: Insights From Molecular Dynamics Simulations von Brancale, Andrea, Shailubhai, Kunwar, Ferla, Salvatore, Ricci, Antonio, Bassetto, Marcella, Jacob, Gary S

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Therapeutically targeting guanylate cyclase‐C: computational modeling of plecanatide, a uroguanylin analog von Brancale, Andrea, Shailubhai, Kunwar, Ferla, Salvatore, Ricci, Antonio, Bassetto, Marcella, Jacob, Gary S

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967 Plecanatide, Like Uroguanylin, Activates Guanylate Cyclase-C Signaling in a pH-Dependent Manner in T84 Cells, and in Murine Intestinal Epithelial Cells and Tissues von Patwa, Viren, Joshi, Apoorva, Thadi, Anusha, Eddy, E. Priya, Palejwala, Vaseem A, Jacob, Gary S, Shailubhai, Kunwar

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925g Plecanatide, a Novel Guanylate Cyclase-C (GC-C) Receptor Agonist, is Efficacious and Safe in Patients with Chronic Idiopathic Constipation (CIC): Results from a 951 Patient, 1... von Miner, Philip B, Surowitz, Ron, Fogel, Ron, Koltun, William, Drossman, Douglas A, Camilleri, Michael, Mangel, Allen, Barrow, Laura, Jacob, Gary S, Shailubhai, Kunwar

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Binding of Sialyl Lewis X to E-Selectin As Measured by Fluorescence Polarization von Jacob, Gary S, Kirmaier, Christine, Abbas, S. Zaheer, Howard, Susan C, Steininger, Christina N, Welply, Joseph K, Scudder, Peter

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W1041 SP-304 to Treat GI Disorders - Effects of a Single, Oral-Dose of SP-304 On Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Healthy Volunteers von Shailubhai, Kunwar, Gerson, William A, Talluto, Craig, Jacob, Gary S

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Azaspirane (N-N-diethyl-8,8-dipropyl-2-azaspiro [4.5] decane-2-propanamine) inhibits human multiple myeloma cell growth in the bone marrow milieu in vitro and in vivo von Hamasaki, Makoto, Hideshima, Teru, Tassone, Pierfrancesco, Neri, Paola, Ishitsuka, Kenji, Yasui, Hiroshi, Shiraishi, Norihiko, Raje, Noopur, Kumar, Shaji, Picker, Donald H., Jacob, Gary S., Richardson, Paul G., Munshi, Nikhil C., Anderson, Kenneth C.

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Treatment of chronic hepadnavirus infection in a woodchuck animal model with an inhibitor of protein folding and trafficking von Block, Timothy M, Lu, Xuanyong, Mehta, Anand S, Blumberg, Baruch S, Tennant, Bud, Ebling, Mathew, Korba, Brent, Lansky, David M, Jacob, Gary S, Dwek, Raymond A

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Plecanatide and dolcanatide, novel guanylate cyclase-C agonists, ameliorate gastrointestinal inflammation in experimental models of murine colitis von Shailubhai, Kunwar, Palejwala, Vaseem, Arjunan, Krishna Priya, Saykhedkar, Sayali, Nefsky, Bradley, Foss, John A, Comiskey, Stephen, Jacob, Gary S, Plevy, Scott E

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Virulence of a phosphoribosylaminoimidazole carboxylase-deficient Candida albicans strain in an immunosuppressed murine model of systemic candidiasis von DONOVAN, Matthew, SCHUMUKE, Jon J, FONZI, William A, BONAR, Sheri L, GHEESLING-MULLIS, Karen, JACOB, Gary S, DAVISSON, Vincent Jo, DOTSON, Stanton B

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Inhibition of HIV replication by amino-sugar derivatives von Fleet, George W.J., Karpas, Abraham, Dwek, Raymond A., Fellows, Linda E., Tyms, A.S., Petursson, Sigthor, Namgoong, Sung K., Ramsden, Nigel G., Smith, Paul W., Son, Jong Chan, Wilson, Francis, Witty, David R., Jacob, Gary S., Rademacher, Thomas W.

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Catalase of Neurospora crassa. 1. Induction, purification, and physical properties von Jacob, Gary S, Orme-Johnson, W. H

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Aromatic Cross-Links in Insect Cuticle: Detection by Solid-State $^{13}$C and $^{15}$N NMR von Schaefer, Jacob, Kramer, Karl J., Garbow, Joel R., Jacob, Gary S., Stejskal, Edward O., Hopkins, Theodore L., Speirs, Roy D.

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Multivalent sialyl-LeX: potent inhibitors of E-selectin-mediated cell adhesion; reagent for staining activated endothelial cells von Welply, Joseph K., Abbas, S. Zaheer, Scudder, Peter, Keene, Jeffery L., Broschat, Kay, Casnocha, Susan, Gorka, Chris, Steininger, Christina, Howard, Susan C., Schmuke, Jon J., Graneto, Matthew, Rotsaert, J.M., Manger, Ian D., Jacob, Gary S.

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Purification and Characterization of a Lymph Node Sulfotransferase Responsible for 6-O-Sulfation of the Galactose Residues in 2′-Fucosyllactose and Other Sialyl LewisX-Related Suga... von Shailubhai, Kunwar, Khai Huynh, Q., Boddupalli, Hymavathi, Yu, Hong H., Jacob, Gary S.

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Anti-HIV drug mechanism von JONES, IAN M, JACOB, GARY S

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