Discovery of Taniborbactam (VNRX-5133): A Broad-Spectrum Serine- and Metallo-β-lactamase Inhibitor for Carbapenem-Resistant Bacterial Infections von Liu, Bin, Trout, Robert E. Lee, Chu, Guo-Hua, McGarry, Daniel, Jackson, Randy W, Hamrick, Jodie C, Daigle, Denis M, Cusick, Susan M, Pozzi, Cecilia, De Luca, Filomena, Benvenuti, Manuela, Mangani, Stefano, Docquier, Jean-Denis, Weiss, William J, Pevear, Daniel C, Xerri, Luigi, Burns, Christopher J

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VNRX-5133 (Taniborbactam), a Broad-Spectrum Inhibitor of Serine- and Metallo-β-Lactamases, Restores Activity of Cefepime in Enterobacterales and Pseudomonas aeruginosa von Hamrick, Jodie C, Docquier, Jean-Denis, Uehara, Tsuyoshi, Myers, Cullen L, Six, David A, Chatwin, Cassandra L, John, Kaitlyn J, Vernacchio, Salvador F, Cusick, Susan M, Trout, Robert E L, Pozzi, Cecilia, De Luca, Filomena, Benvenuti, Manuela, Mangani, Stefano, Liu, Bin, Jackson, Randy W, Moeck, Greg, Xerri, Luigi, Burns, Christopher J, Pevear, Daniel C, Daigle, Denis M

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Discovery of VNRX-7145 (VNRX-5236 Etzadroxil): An Orally Bioavailable β‑Lactamase Inhibitor for Enterobacterales Expressing Ambler Class A, C, and D Enzymes von Trout, Robert E, Zulli, Allison, Mesaros, Eugen, Jackson, Randy W, Boyd, Steven, Liu, Bin, Hamrick, Jodie, Daigle, Denis, Chatwin, Cassandra L, John, Kaitlyn, McLaughlin, Lisa, Cusick, Susan M, Weiss, William J, Pulse, Mark E, Pevear, Daniel C, Moeck, Greg, Xerri, Luigi, Burns, Christopher J

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A mild and selective method for the cleavage of tert-butyl esters von Jackson, Randy W

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The Discovery of Pyrano[3,4-b]indole-Based Allosteric Inhibitors of HCV NS5B Polymerase with In Vivo Activity von LaPorte, Matthew G., Jackson, Randy W., Draper, Tandy L., Gaboury, Janet A., Galie, Kristin, Herbertz, Torsten, Hussey, Alison R., Rippin, Susan R., Benetatos, Christopher A., Chunduru, Srinivas K., Christensen, Joel S., Coburn, Glen A., Rizzo, Christopher J., Rhodes, Gerry, O'Connell, John, Howe, Anita Y. M., Mansour, Tarek S., Collett, Marc S., Pevear, Daniel C., Young, Dorothy C., Gao, Tiejun, Tyrrell , D. Lorne J., Kneteman, Norman M., Burns, Christopher J., Condon, Stephen M.

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The discovery and structure–activity relationships of pyrano[3,4- b]indole-based inhibitors of hepatitis C virus NS5B polymerase von Jackson, Randy W., LaPorte, Matthew G., Herbertz, Torsten, Draper, Tandy L., Gaboury, Janet A., Rippin, Susan R., Patel, Ravi, Chunduru, Srinivas K., Benetatos, Christopher A., Young, Dorothy C., Burns, Christopher J., Condon, Stephen M.

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Total Synthesis of the Antiparasitic Agent Avermectin B1a von White, James D, Bolton, Gary L, Dantanarayana, Anura P, Fox, Christina M. J, Hiner, Roger N, Jackson, Randy W, Sakuma, Kazuhiko, Warrier, Ulhas S

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Total Synthesis of Rutamycin B, a Macrolide Antibiotic from Streptomyces aureofaciens von WHITE, James D., HANSELMANN, Roger, JACKSON, Randy W., PORTER, Warren J., OHBA, Yoshihiro, TILLER, Thomas, WANG, Shan

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Identification of TNF-α inhibitors from a split-Pool library based on a tyrosine-Proline peptidomimetic scaffold von Jackson, Randy W., Tabone, John C., Howbert, J.Jeffry

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Total Synthesis of Rutamycin B, a Macrolide Antibiotic from Streptomyces a ureofaciens von White, James D, Hanselmann, Roger, Jackson, Randy W, Porter, Warren J, Ohba, Yoshihiro, Tiller, Thomas, Wang, Shan

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Benzobicyclooctanes as novel inhibitors of TNF-α signaling von JACKSON, Randy W, GELINAS, Richard, BAUGHMAN, Ted A, COX, Thomas, HOWBERT, J. Jeffry, KUCERA, Kristin A, LATHAM, John A, RAMSDELL, Fred, SINGH, Devinder, DARWISH, Ihab S

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Wind-resistant container systems, anchoring systems, and methods of use von JACKSON RANDY W

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Beta-lactamase inhibitors von Trout, Robert E. Lee, Jackson, Randy W, McGarry, Daniel, Daigle, Denis, Liu, Bin, Pevear, Daniel C, Burns, Christopher J

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BETA-LACTAMASE INHIBITORS von JACKSON, Randy, W, BURNS, Christopher, J, MCGARRY, Daniel, DAIGLE, Denis, PEVEAR, Daniel C, LIU, Bin, HAMRICK, Jodie, TROUT, Robert E. Lee

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WIND-RESISTANT CONTAINER SYSTEMS, ANCHORING SYSTEMS, AND METHODS OF USE von JACKSON RANDY W

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Synthesis of a C-1 epi taxinine intermediate using the type 2 intramolecular Diels-Alder approach von Jackson, Randy W., Shea, Kenneth J.

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Total synthesis of rutamycin B via Suzuki macrocyclization von White, James D., Jackson, Randy W., Hanselmann, Roger

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BETA-LACTAMASE INHIBITORS von DAIGLE, DENIS, TROUT, ROBERT E. LEE, JACKSON, RANDY W, LIU, BIN, PEVEAR, DANIEL C, BURNS, CHRISTOPHER J, HAMRICK, JODIE, MCGARRY, DANIEL

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Penicillin-binding protein inhibitors von Chu, Guo-Hua, Boyd, Steven A, Jackson, Randy W, Yao, Jiangchao, Lucas, Matthew, Daigle, Denis, Hamrick, Jodie, Burns, Christopher J, Mesaros, Eugen F

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BETA-LACTAMASE INHIBITORS von DAIGLE, DENIS, TROUT, ROBERT E. LEE, JACKSON, RANDY W, LIU, BIN, PEVEAR, DANIEL C, BURNS, CHRISTOPHER J, HAMRICK, JODIE, MCGARRY, DANIEL

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