Discovery of Taniborbactam (VNRX-5133): A Broad-Spectrum Serine- and Metallo-β-lactamase Inhibitor for Carbapenem-Resistant Bacterial Infections von Liu, Bin, Trout, Robert E. Lee, Chu, Guo-Hua, McGarry, Daniel, Jackson, Randy W, Hamrick, Jodie C, Daigle, Denis M, Cusick, Susan M, Pozzi, Cecilia, De Luca, Filomena, Benvenuti, Manuela, Mangani, Stefano, Docquier, Jean-Denis, Weiss, William J, Pevear, Daniel C, Xerri, Luigi, Burns, Christopher J

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The discovery and structure–activity relationships of pyrano[3,4- b]indole-based inhibitors of hepatitis C virus NS5B polymerase von Jackson, Randy W., LaPorte, Matthew G., Herbertz, Torsten, Draper, Tandy L., Gaboury, Janet A., Rippin, Susan R., Patel, Ravi, Chunduru, Srinivas K., Benetatos, Christopher A., Young, Dorothy C., Burns, Christopher J., Condon, Stephen M.

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A mild and selective method for the cleavage of tert-butyl esters von Jackson, Randy W

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VNRX-5133 (Taniborbactam), a Broad-Spectrum Inhibitor of Serine- and Metallo-β-Lactamases, Restores Activity of Cefepime in Enterobacterales and Pseudomonas aeruginosa von Hamrick, Jodie C, Docquier, Jean-Denis, Uehara, Tsuyoshi, Myers, Cullen L, Six, David A, Chatwin, Cassandra L, John, Kaitlyn J, Vernacchio, Salvador F, Cusick, Susan M, Trout, Robert E L, Pozzi, Cecilia, De Luca, Filomena, Benvenuti, Manuela, Mangani, Stefano, Liu, Bin, Jackson, Randy W, Moeck, Greg, Xerri, Luigi, Burns, Christopher J, Pevear, Daniel C, Daigle, Denis M

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Identification of TNF-α inhibitors from a split-Pool library based on a tyrosine-Proline peptidomimetic scaffold von Jackson, Randy W., Tabone, John C., Howbert, J.Jeffry

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Discovery of VNRX-7145 (VNRX-5236 Etzadroxil): An Orally Bioavailable β‑Lactamase Inhibitor for Enterobacterales Expressing Ambler Class A, C, and D Enzymes von Trout, Robert E, Zulli, Allison, Mesaros, Eugen, Jackson, Randy W, Boyd, Steven, Liu, Bin, Hamrick, Jodie, Daigle, Denis, Chatwin, Cassandra L, John, Kaitlyn, McLaughlin, Lisa, Cusick, Susan M, Weiss, William J, Pulse, Mark E, Pevear, Daniel C, Moeck, Greg, Xerri, Luigi, Burns, Christopher J

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Total Synthesis of Rutamycin B, a Macrolide Antibiotic from Streptomyces a ureofaciens von White, James D, Hanselmann, Roger, Jackson, Randy W, Porter, Warren J, Ohba, Yoshihiro, Tiller, Thomas, Wang, Shan

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Synthesis of a C-1 epi taxinine intermediate using the type 2 intramolecular Diels-Alder approach von Jackson, Randy W., Shea, Kenneth J.

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The Discovery of Pyrano[3,4-b]indole-Based Allosteric Inhibitors of HCV NS5B Polymerase with In Vivo Activity von LaPorte, Matthew G., Jackson, Randy W., Draper, Tandy L., Gaboury, Janet A., Galie, Kristin, Herbertz, Torsten, Hussey, Alison R., Rippin, Susan R., Benetatos, Christopher A., Chunduru, Srinivas K., Christensen, Joel S., Coburn, Glen A., Rizzo, Christopher J., Rhodes, Gerry, O'Connell, John, Howe, Anita Y. M., Mansour, Tarek S., Collett, Marc S., Pevear, Daniel C., Young, Dorothy C., Gao, Tiejun, Tyrrell , D. Lorne J., Kneteman, Norman M., Burns, Christopher J., Condon, Stephen M.

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Total Synthesis of the Antiparasitic Agent Avermectin B1a von White, James D, Bolton, Gary L, Dantanarayana, Anura P, Fox, Christina M. J, Hiner, Roger N, Jackson, Randy W, Sakuma, Kazuhiko, Warrier, Ulhas S

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Total Synthesis of Rutamycin B, a Macrolide Antibiotic from Streptomyces aureofaciens von WHITE, James D., HANSELMANN, Roger, JACKSON, Randy W., PORTER, Warren J., OHBA, Yoshihiro, TILLER, Thomas, WANG, Shan

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Stereoselective elaboration of the tricyclo[9.3.1.0 3,8]pentadecane ring system. Atropisomeric control of stereochemistry von Jackson, Randy W., Higby, Richard G., Shea, Kenneth J.

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Benzobicyclooctanes as novel inhibitors of TNF-α signaling von JACKSON, Randy W, GELINAS, Richard, BAUGHMAN, Ted A, COX, Thomas, HOWBERT, J. Jeffry, KUCERA, Kristin A, LATHAM, John A, RAMSDELL, Fred, SINGH, Devinder, DARWISH, Ihab S

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Total synthesis of rutamycin B via Suzuki macrocyclization von White, James D., Jackson, Randy W., Hanselmann, Roger

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The chemistry of C-aromatic taxane derivatives atropisomer control of reaction stereochemistry von Jackson, Randy W., Higby, Richard G., Gilman, Jeffrey W., Shea, Kenneth J.

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Wind-resistant container systems, anchoring systems, and methods of use von JACKSON RANDY W

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WIND-RESISTANT CONTAINER SYSTEMS, ANCHORING SYSTEMS, AND METHODS OF USE von JACKSON RANDY W

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Beta-lactamase inhibitors von Trout, Robert E. Lee, Jackson, Randy W, McGarry, Daniel, Daigle, Denis, Liu, Bin, Pevear, Daniel C, Burns, Christopher J

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BETA-LACTAMASE INHIBITORS von JACKSON, Randy, W, BURNS, Christopher, J, MCGARRY, Daniel, DAIGLE, Denis, PEVEAR, Daniel C, LIU, Bin, HAMRICK, Jodie, TROUT, Robert E. Lee

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BETA-LACTAMASE INHIBITORS von DAIGLE, DENIS, TROUT, ROBERT E. LEE, JACKSON, RANDY W, LIU, BIN, PEVEAR, DANIEL C, BURNS, CHRISTOPHER J, HAMRICK, JODIE, MCGARRY, DANIEL

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